Dneo011015.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila neotestacea
Gene Symbol
-
Assembly
GCA_035044365.1
Location
JAWNMD010000273.1:5314684-5318064[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.12 9.2 7.1 1.4 1 21 235 255 235 256 0.94
2 7 0.0047 0.36 11.6 4.1 1 23 262 285 262 285 0.96
3 7 0.00051 0.039 14.6 1.6 2 23 292 314 292 314 0.97
4 7 0.021 1.6 9.5 3.8 1 23 358 380 358 380 0.99
5 7 0.029 2.2 9.1 0.7 1 23 388 410 388 410 0.97
6 7 0.0075 0.58 10.9 0.2 1 23 415 437 415 437 0.95
7 7 0.00033 0.025 15.2 2.6 1 23 492 514 492 514 0.98

Sequence Information

Coding Sequence
ATGAACAGTCAACTTAATCCGAGCACCTACcgcaaattcaataatttgctAAGCAGCGGCGCTGTTACCGTTACCGGTCCCGGCCAGCCGCGCATATTGAAAACTACACGCCTTGCAACATCCGGAGGCGGTGGTAATCTGTCTGCAGCatcccagcagcagcagcaacaacagcagcagaataCCATGGATTCGGATGCTGGGGCACGTTGTTACATTTGCGATGAACTCTTGCTGTCAAATCAAACGCAGTCACCATTGACGGAAATGTGCACCTCGCACACATCCACGAAGTTTCCGAATAAGTTGGCCCAACTTGTAGGCGAAGCATTCTTGGTGATTGTCTGCAATGAGGATTTCGTATGCTCACGGTGTACCAACCTGGTCAACTACTATGATCGCCTGGAGAATGATGTGGAGCGTGTAAAGTCCAATTTGCTCAATTTGTTGAACAAAAAGTATGGTATCAATGAGGACAGCGGTGGCAGCCACTCGGATGCAGCAAGTCCTCcgcttaaaatgcaaaaaatgtcCGGCATTGCCGCAAATCGTTCGTTGGAAGAGGCAGGAGGAGCTGGCGGAGATGTGAGGCAACGGAAACTCGCTCAGCAAGCAACCCCAGGTTCGCAAGGTTTGAAGGTATCGTCTCCCCAAGGAGGCATTGTTGGCACACAACAGGTGCAACGGAAGGCAACCAAGATTTACAAGTGCACATCGTGCGATTACAAGACCTCGGATATGCGTTTGTTTAATACACATTATGAGACATGCAAACAGCAGACTTTCCAGTGCAAGACCTGTCGCAAGATCTTCCCTCACTTTGGCGCCATGAAGCATCATATGGTCAGGGACCACAATACTGCTATGGATAACACATGTGCCATGTGTCACATTAATTTTGTGAATGAGAATAGCTTGAGAAAGCATATGGAAACGAATCATGCAACAAATGTATTGGTTActagcacaacaacaattcctgctgctgctgctccggttacagctgcagctgctgctgccgctgctgctgctggagtGACAGAGTCAGTTACTGTCACTGGCTCGGCTTTATATACATGCAATCACTGTCAATTCAAGTCGACGGACAAGGGTGTCTTTGATGAGCACATGCGCAAGCATGTCACCAACAAACCGAAACCATTCAAATGTCGCTTGTGCTCGCAACGATTTGAGACACGCGAAGCTGCAACTGTGCACGCCAAGCAACATCAGACTAACTACTTCAAGTGTGGCCAATGTGCGATGAGTTTCCCCAAACGTGAGTTGCTTGTGAAGCACGCTGAACTCCATCAGTCCGAGAAGCTGGCAGCTGCTGGCGGTGGCAGTCAGAATTTGAATACCCAGAAGCTACTGCAGGAGACCATTGATGAGGCACTCAGCGATAGTGTGCCCGCCCAGGCAGGCACTACTGTGGTGACTTCGGCTGCTGAGGCAGAGAATAACATACGCTTCTTCTCGTGCAGCATCTGCTCGTTGACATTCATCCAAGAGACGTACTACAATCACCATATGGAAACTCACAGACGTGACAAGAAGAACGCCGCAGCTGGAGGAGGTGCTGGTGGAACCACAGCTCTCAATTCTGCAGCTACAGCGCTGCTCAGCGATGAGCCGGGAGATTCTGGTGTGGGCGTAAAGGAAGAGTCTAATGAGCAAAATGCCGAGGCAGATATTGAGAGTCTCTTTGAGAAATTGCATTCGGAGAAGAACGACAGCGAGAAGAAGAATGAAATGGTCATCACACAGGAGGGGAGTGGTGGCATTACTTTTAACATAACCATACCACAAGTTGATGCCACTGGCGATCAGGCCGAGAAGAATTCACCCAATTCCCAAGCTCCAGTTTCGGTTAGCATTGATATGCCAGTATTGGATCAGGCCGAAGAAGAGGAATCACAATCCCAgggcagcagcgacaacaaatcTGGTGAGGCAAAGTCCAATGCTGCACCCGTTTCCATGCCCAGTCTGGATGATGACAATGAGGCAGCTGCCGCAAATGCAGCAGACGCAACTGATGGCAATGCAGCCAGCAGCAAGACAAGCGGGAAATCCAATACCAAGGCAGCCCAAGCAGCAGCCAAGGAGAAGGCCAAAGAAGCTGCCGCAGAAGCAGCCGAGGCTGAAGGCGACGCGGTTAAACATGAGTCCGAGGAGACAACAGCTGAACAGGCAGCTGAATCAGCTGCTGCCGAGGAAGCTGCTGAAGccgaagcagcagcagccgctggGGAAGGAGAAGCATCCGAAGGAGCTGGCGGAGAACAACAAGTCGCCATGGAATTGGATGAGGCCATGCAGGCTCAAGTCGATGGTGGACAAATCAAGTTTATTGTCAATGAGAACGGACATCTGTTGCAGCTCGATAATCACATCCTGACAGATGCCGATGGCAATCAGATTATAGTGCAAGATCCTGAGCAAATACAGCAGTTGCTCCAAAGTGTTGGTGTGTTGCAGTCGGGCGAGGGACTCGAGGGCGAGACTCTTCAAATGATGACCGATGGCAGTGGCCAGATGGTGTTGGTACATGGCGATAACAATGAACAGCAGCTGATCGATGCTTCACTGCTCAATTCCGAGGGTCAAATCATAATACAACAGGGCCAGGATGGTGAAGAGGGTCCACATGTTATCAGCGAGGATGGAACTCGCATACCCGTGTCAGTATCATACACGGAGGATGGCCAACCCATTGTGCAAGTGCAGCAACAAGTGCTGGAGGCGGCCCAGGCCAGTGCCGAGGAGAAGGAGGCGGCAGCCCAAGCTGAGGAAGCTGGTGAGGGCACACAAACATCGGAAGCTGTTACAGTGACAACTGCAGCCACATCCGTTACCACAAGCACGGCCAGCAGTAGCTCTGGTGGCACAGCCGGATTCTTTGCGCTTGAAGAATTCGCCGAGACGAAAGCCGACTAG
Protein Sequence
MNSQLNPSTYRKFNNLLSSGAVTVTGPGQPRILKTTRLATSGGGGNLSAASQQQQQQQQQNTMDSDAGARCYICDELLLSNQTQSPLTEMCTSHTSTKFPNKLAQLVGEAFLVIVCNEDFVCSRCTNLVNYYDRLENDVERVKSNLLNLLNKKYGINEDSGGSHSDAASPPLKMQKMSGIAANRSLEEAGGAGGDVRQRKLAQQATPGSQGLKVSSPQGGIVGTQQVQRKATKIYKCTSCDYKTSDMRLFNTHYETCKQQTFQCKTCRKIFPHFGAMKHHMVRDHNTAMDNTCAMCHINFVNENSLRKHMETNHATNVLVTSTTTIPAAAAPVTAAAAAAAAAAGVTESVTVTGSALYTCNHCQFKSTDKGVFDEHMRKHVTNKPKPFKCRLCSQRFETREAATVHAKQHQTNYFKCGQCAMSFPKRELLVKHAELHQSEKLAAAGGGSQNLNTQKLLQETIDEALSDSVPAQAGTTVVTSAAEAENNIRFFSCSICSLTFIQETYYNHHMETHRRDKKNAAAGGGAGGTTALNSAATALLSDEPGDSGVGVKEESNEQNAEADIESLFEKLHSEKNDSEKKNEMVITQEGSGGITFNITIPQVDATGDQAEKNSPNSQAPVSVSIDMPVLDQAEEEESQSQGSSDNKSGEAKSNAAPVSMPSLDDDNEAAAANAADATDGNAASSKTSGKSNTKAAQAAAKEKAKEAAAEAAEAEGDAVKHESEETTAEQAAESAAAEEAAEAEAAAAAGEGEASEGAGGEQQVAMELDEAMQAQVDGGQIKFIVNENGHLLQLDNHILTDADGNQIIVQDPEQIQQLLQSVGVLQSGEGLEGETLQMMTDGSGQMVLVHGDNNEQQLIDASLLNSEGQIIIQQGQDGEEGPHVISEDGTRIPVSVSYTEDGQPIVQVQQQVLEAAQASAEEKEAAAQAEEAGEGTQTSEAVTVTTAATSVTTSTASSSSGGTAGFFALEEFAETKAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00471226;
90% Identity
iTF_00584053;
80% Identity
-