Basic Information

Insect: Drosophila neotestacea
Gene Symbol: -
Assembly: GCA_035044365.1
Location: JAWNMD010000046.1:1736353-1742560[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.069 5.3 7.9 0.4 1 23 521 543 521 543 0.96

2 7 0.33 26 5.7 0.6 2 19 548 565 547 566 0.97

3 7 6.3e-06 0.00048 20.6 0.3 1 23 572 594 572 594 0.99

4 7 0.0032 0.25 12.1 4.2 1 23 604 626 604 626 0.98

5 7 0.00075 0.057 14.1 0.1 2 23 633 654 632 654 0.95

6 7 1.2e-06 8.9e-05 22.9 1.3 1 23 660 682 660 682 0.98

7 7 8.7e-05 0.0067 17.0 3.5 1 23 688 710 688 710 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.069	5.3	7.9	0.4	1	23	521	543	521	543	0.96
2	7	0.33	26	5.7	0.6	2	19	548	565	547	566	0.97
3	7	6.3e-06	0.00048	20.6	0.3	1	23	572	594	572	594	0.99
4	7	0.0032	0.25	12.1	4.2	1	23	604	626	604	626	0.98
5	7	0.00075	0.057	14.1	0.1	2	23	633	654	632	654	0.95
6	7	1.2e-06	8.9e-05	22.9	1.3	1	23	660	682	660	682	0.98
7	7	8.7e-05	0.0067	17.0	3.5	1	23	688	710	688	710	0.98

Sequence Information

Coding Sequence: atggccagcagcagcaacacaataacaaatgcaagcaacaacaacacattgcTGCCATCTCTATTTgccggcaacagcaacaacagcagcaataacacaacagcaacaacagttgccgcCAAAGATATGGACGGACTGATTGCCATCAATGATAGCGCATTATCGCAACAAATCGAATTTATACTACAAGATGCTCCCATGGAGCAGGATGATGaagagcagcaacatcatcagctgCAGCTTAAtatgacagcagcagcagcagcagcaacaacgacggCGACGTCAAAGCTCGATAACCACCCACcgataacagcaacaacaaatgcaacaataacgacaacaacaaccaacagcgCTTCcccatacaacaacaacaaccatctcaacaataataataataataataacaacaacattagcagcaacaacaacaacaatagtttgAGTGTTGTTGAGGatcatcagcaactgttgctgcaacaacatcgcgcccagcagcaacaacatcatctgCTTAATGGACGCCGCATCATCATACAATCAACATCAGGCCAACttaccagcaacaacaccactGTTTTATCCGCCAGCGACATTAAAGAGGAACAACAGGAATTCGATGATGAACCacaggaggaggaagaggaagaggatcCCGAGTTGAATGATGAGAATTTACAGGATATTGAAGAGGAGGCGCAGGCAGCCGAAGCTGATGAAGAGCCTGAAACGGCGGCACATTTGCAACaccatcatcaacatcatcatcatcatgcacagcagcaacaccatcatcatcaacagcagcagcaacagcaacatcttaaccagcaacaacaacatctgcaAACGCAGGTGAAACTCGAATTGGATGATCTGCcggatgaggatgatgaagaggaggaggatgatgatgaacaTATGACGCAGccaacgcaacaacaacaacaacagctagaGACacttcaacaacaattggaGTACTCGACAACGGCACAACAGTTGGTGTTGCCAGCTGGTAGCATTGTGAGCACAACAACACGTGCATTGGCTGTGCCCGTGTCGGAGGCAGCATTGGTGCAACTGCAACGTCGTCCCGTCTACATAAGCAATGCCACAATGAGCAGTTTGGCGGGTGCAACATATGTGCGTatgccagcagcagctgttatCAGTCGCAGTCCGATGACGGTGTTGAATGTGGTGCAACAAACGGGTGGATCGACAGCACAGTTGATATTGCAAGCGGCAAcgacggcagcagcagcaacaacaacgacacaaCAGCAAGCacccacagcagcagcagtagcagcagcagctgcaacaacaaccacaacagcaacgccGTCCCCCAGCaatgagcaacagcagcagcaacaacttgcaGCAATTGCACTcgcccagcagcagcaacaacaacagcagcagcagcagcaacaacagcaacaggctcagcagcaacagcaggcacaacagcagcaacaacagcaacaacatcatcagtCCATTAAACCAGCGCCTGCCACAAGCACTgtggcaacatcaacaaccaGTTACCAGTGCATGGAATGTGTCGAAAAATTCGATTCAAAGGAACTTTTTGACATTCATCGCAGTGGACACGCGAACAACATGAAATGCGCCATCTGCAACATGGTGTTGAAATCATTGAAAAACTATGAGAAACATTGTTTACGTTGCAAACCCTACGAATGCCAGATTTGTGGTCGTGTTGTACGCTTTCGTCCCAATTTCATAAAACATATGCGCGTGCATACGGGTCAACAATCGGAGAGGCATAAATACAAGTGCGAGGTGTGCCACAAGGAGTTTATGAGCTTTGAATACTTCAAGGTCCACAAGAAGATCCACAATGAGAATGTCAATCTAACGTGTGAAATATGTGGCAAGGTCTTTAGTGCACTTGCCTCGCTCCGTGGACACTCCAAGCTGCATTCGGGCGTCAAGTTGCACAAATGTGATGTTTGTGGCAAAGGATTTGGTCAGcgttataatttgaaaattcatgcgcgcacacacacaggagACTTTCCCTTTGAGTGTAAGGTGTGTAAAAAGAAGTTGCACACACAATCCTCGTTGCAGACGCATATGCAGGTGCATTTACGTGATCAACccaaaggcagcaacaacaacaacagcagcagcggcagcagcagcaacgccgcaagcagcagcagtaacaacaacaccagcaacaatagtaataataatgttaatgttgCAACGAGCGCTGTTAAAATCGAACCTGATTTGGACAGACCAAGCACAAgtctgcaacagcaacagttgcagcaacaacatcatcagcagcaccAACACCATGAAATGGATGTGGATGATCTGTCGGGTTTGAGTGACGAAGAGCATGATGTTGCCGCTGTCCATAACTCGACCAATAATAATCGTTTAACCACCGGCGAGGATTCCTCAAATGAATCCTTATCGAATGCCTCGCTTCAGCAGCCGCTTTCCTCCTCAGCCAGCTCATCGCactcgcagcagcagcaacaacaacaatatattgtTTCGACGCCCACGCGcacaattgttattaaaaactacatgcaaccgcagcagcagcaacaacaatcaacagatgcaacaacagcaaatggtGCTGCTGGAAATGGCAATTGTTCGAGTGTGCTGCACACACAGGTCATCCAAAGCGGTGCAGGCACCAGCAATGGCCATCACATCATTAACAACACCTCCactagcagcagcagcagcagcaacaacagcaatcacaacagcagcagcagcggcaacagcatgTTAAACAACGGCAATAGTTgtacaaacagcaacagcaatacaaacagcagcatcatcagtaacaacaacaacaccggcAGCAGCAATGCTGCAGTGCCAGCAACAGCGAATGCCAACAGCAATCTCGCCCAGCAACTGTTGCGTAAAACGCCCATCATTCATTCAACGGGCACACTCAGCTCGGCGCTGGCGAGTGTTGTCCAACAGACGAGCGTTGGATCGCCGGCACAATCGCCATCATCTTCATCGCAATCGTGTTCCTCCACAGTGCTGGTGTCCAAGGCGACGGGTGTGCCTCTTTCCATAGCCTCATCCGCAGCATTGGGCGGCTCCACAATAATACGCAGTACGCGTaatcatcaacagcaacatccacagcagcagcagcaacaacagcagcaacaggcgcAAAGCAATCAGCgaggaggagcaggaggaggaggaggaggacaACAACAGCGTAATAACCACCGAAACCACCACCGACGTCGTCATTTGGCGGATAtggacgacgatgatgatgatgacgatgatgatgaggatgagacGAGTTTACAATTGCGAGCTGCCACAAAtggacatcatcatcagcatcaacatcaacatcagcagcagcagcagcaacagcaacaatcgcaTCAATTGAATCATAATCATAGCCACAATCATCATAATAATCATCACAATCATCAGAATCATAATCATCAGCATCataatcacaatcacaatcatcATCACAGTCATagtcacaatcacaatcatcataatcattttgatgatgatgatgacgatgagaAATCATCACCGTCCCTGGCAACAGCCGCTATCATCAAAGTTGAACCGAATCTCTATTCATCCGGCTCTGGCGATAATTCCAATGATATGTTCATTAAAGAGGAGGTCATGTTTGAAGATTCCGCCGCACCGCATTCACCACAATCGCCGCCAAGTTCGAAATTTCGTATATCGAATTTTGATAGCGATCTAGTCGATGATCATGTCGATTTGAATCATTCTCTGCCACCATATGGTAATCTATTTGAGCCACATTCAATACGGGATAGCATACCCGTCCAACTATATccggatgatgatgatgattttcGTTTGGATCATAGTTCATTGGGTGGCCTACACAATACATCGTCATCGACAACCGATGgtgatttcattaaaaaggAATGGGTCTATGGCAGCGGTACGAGCAGTTATGCCATGAATGGAAAATTCGATGATGATAGCGATGCTCTCTGCGATGCCGCcaatttcatttacaattgA
Protein Sequence: MASSSNTITNASNNNTLLPSLFAGNSNNSSNNTTATTVAAKDMDGLIAINDSALSQQIEFILQDAPMEQDDEEQQHHQLQLNMTAAAAAATTTATSKLDNHPPITATTNATITTTTTNSASPYNNNNHLNNNNNNNNNNISSNNNNNSLSVVEDHQQLLLQQHRAQQQQHHLLNGRRIIIQSTSGQLTSNNTTVLSASDIKEEQQEFDDEPQEEEEEEDPELNDENLQDIEEEAQAAEADEEPETAAHLQHHHQHHHHHAQQQHHHHQQQQQQQHLNQQQQHLQTQVKLELDDLPDEDDEEEEDDDEHMTQPTQQQQQQLETLQQQLEYSTTAQQLVLPAGSIVSTTTRALAVPVSEAALVQLQRRPVYISNATMSSLAGATYVRMPAAAVISRSPMTVLNVVQQTGGSTAQLILQAATTAAAATTTTQQQAPTAAAVAAAAATTTTTATPSPSNEQQQQQQLAAIALAQQQQQQQQQQQQQQQQAQQQQQAQQQQQQQQHHQSIKPAPATSTVATSTTSYQCMECVEKFDSKELFDIHRSGHANNMKCAICNMVLKSLKNYEKHCLRCKPYECQICGRVVRFRPNFIKHMRVHTGQQSERHKYKCEVCHKEFMSFEYFKVHKKIHNENVNLTCEICGKVFSALASLRGHSKLHSGVKLHKCDVCGKGFGQRYNLKIHARTHTGDFPFECKVCKKKLHTQSSLQTHMQVHLRDQPKGSNNNNSSSGSSSNAASSSSNNNTSNNSNNNVNVATSAVKIEPDLDRPSTSLQQQQLQQQHHQQHQHHEMDVDDLSGLSDEEHDVAAVHNSTNNNRLTTGEDSSNESLSNASLQQPLSSSASSSHSQQQQQQQYIVSTPTRTIVIKNYMQPQQQQQQSTDATTANGAAGNGNCSSVLHTQVIQSGAGTSNGHHIINNTSTSSSSSSNNSNHNSSSSGNSMLNNGNSCTNSNSNTNSSIISNNNNTGSSNAAVPATANANSNLAQQLLRKTPIIHSTGTLSSALASVVQQTSVGSPAQSPSSSSQSCSSTVLVSKATGVPLSIASSAALGGSTIIRSTRNHQQQHPQQQQQQQQQQAQSNQRGGAGGGGGGQQQRNNHRNHHRRRHLADMDDDDDDDDDDEDETSLQLRAATNGHHHQHQHQHQQQQQQQQQSHQLNHNHSHNHHNNHHNHQNHNHQHHNHNHNHHHSHSHNHNHHNHFDDDDDDEKSSPSLATAAIIKVEPNLYSSGSGDNSNDMFIKEEVMFEDSAAPHSPQSPPSSKFRISNFDSDLVDDHVDLNHSLPPYGNLFEPHSIRDSIPVQLYPDDDDDFRLDHSSLGGLHNTSSSTTDGDFIKKEWVYGSGTSSYAMNGKFDDDSDALCDAANFIYN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00586270;
90% Identity: iTF_00584046;
80% Identity: -