Basic Information

Insect: Drosophila neotestacea
Gene Symbol: -
Assembly: GCA_035044365.1
Location: JAWNMD010000757.1:2292584-2294858[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1.7e-05 0.0013 19.2 2.6 1 23 352 374 352 374 0.97

2 7 3.8e-05 0.0029 18.2 0.4 1 23 380 403 380 403 0.98

3 7 0.02 1.6 9.6 1.2 1 23 409 432 409 432 0.87

4 7 3.8e-05 0.0029 18.2 1.4 1 23 469 491 469 491 0.97

5 7 6.6e-05 0.005 17.4 1.1 1 23 497 519 497 519 0.98

6 7 2.4e-05 0.0019 18.8 0.7 1 23 525 547 525 547 0.98

7 7 0.0006 0.046 14.4 2.7 1 22 553 574 553 577 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1.7e-05	0.0013	19.2	2.6	1	23	352	374	352	374	0.97
2	7	3.8e-05	0.0029	18.2	0.4	1	23	380	403	380	403	0.98
3	7	0.02	1.6	9.6	1.2	1	23	409	432	409	432	0.87
4	7	3.8e-05	0.0029	18.2	1.4	1	23	469	491	469	491	0.97
5	7	6.6e-05	0.005	17.4	1.1	1	23	497	519	497	519	0.98
6	7	2.4e-05	0.0019	18.8	0.7	1	23	525	547	525	547	0.98
7	7	0.0006	0.046	14.4	2.7	1	22	553	574	553	577	0.91

Sequence Information

Coding Sequence: atgaaAGGACGACATCCAGGGggattacaatttcaaatgggATTGTGTTCGAAGAGAACGCTGAGACCAGGCGCAGTGCCCTGCATCAATAAGAATGATATGAGTGAAGCTGAACGGGAGAAATCGGAAAAGCGCAAGAATCAAAAGTTGGTTGCCGAACTGCTCGAGGAAGCGGAAGCACGAGAAGCAGCCGAGGCCAGTGGAGCAATTACAATTGCTCCAGACTTTGTCCGAAATACAGGCATTGTCTCTGTACCCGATTTTGTTAGCGCCACCGGAAATGCCTTCGTTCCATTTacagagaaagaagaagagccTACAGAGAAAGACCCTTTGGCTGATGAACAGGTGGAGACTGACAAGTCTACAAAGagcataaaaaaacaaaattgtcgCACGTGCTCTCGACCCTTTGTGGTTGATGAAAAGGCCAAGGATCTCGCCAACGAAGAAAACGCTGTGGTGTTATATCACATTGAAGTTATTACCGGAATTTGGATCTCATGCAAAGAAGAAATTGCACGATTCATGTGCTCCACTTGTGTTGACAACTTGCGCACAGCGATTGAGTTCCGAGAAACCTGCATACGAACAGAGCTTCAGCTTACAATTGGCGGTGATGATGAACAACCAGATGATATCAAAGAGAACGACATGGAACTTGACGACAAGGATGATCATTCGTTTAATGATGATATAAAAGAGGAGGAGTTTATATCAGTATTTCCGGCAGATGGAGAAAATGGACAAACAACAGTTGAATCCTTATCAAGATCAATGAATAAGAAAACGGGACAGGTATTACATCCAGCAGCAGTGGATCCAAATAGCCTTGCATTAGGAGCACAGATCTATGAGGATCTTTTGAATGAATATCGTGGAAAGGATAAACAACCGCGTCCCAGACAGAAAATGGCAGAAAGTCCAAAGACCCAGCAAGTCCAAAGACAACGAAAACAAAGACCTCGGGAGCCAGCGCCCAAACGTACAAAACGGTCGAGAGAGGAAAAAAATCGAATACGACGTGAACATATCAGAGCCTTGCCCCTGAATCATGTATGCGATCAGTGCGGTGCATCCTTTCGGGTGAAATGCAATCTGACAATACATATGCTGCGTCATTCGCGCACCAAGAATTATACATGTCCCGAATGTCCTAAGCAATTTTACGACGCCTATATGAGAAACATGCATATCCGTGTGCGTCACAGAGGGGAGCTCCCATTTGCCTGCAATTATTGTAAGAAAGCGTATAGTTCATCCAACATGCGTTATTTGCACGAAAAGAATGTTCATGGAGCATCTCCACGCATTCACAGGAATGTAAATAAGTTGAACCAAAGGATTGAACTCAGAGCAGAAAATCAGTCGCAAGCGAATAAACAGCCAAGGGAAAATGTTCGCCACTCTTGCATGTACTGCGATAAAAGCTATGCTACAAAGTACGCGCTCAACGGACATATTAATCAGCATTTGGGCCTTAATCCCTTCAAATGCAAGGTCTGCGGTATGAGTTTTCCAAGTCCTCAATCGAAAAAGAAGCACGAGATGAGGCACGATAGTAAACGTCCCTTCGAGTGTGACATTTGCCTCAAAGGATTCTACACACGCAGCAAGCTGAAAGAGCATGAAAGGATTCACACTGGTGAACGTCCTTACAGATGTGACATTTGCGATGCCTTTTTCCGATACAAGTTCAACCTATATTCGCATCAGTTTAGTAAAATGCATAAGGAAAATCTTCAAAAGGCGCAAACGGATCCAATTGTCGAGGATTCAAGTTAA
Protein Sequence: MKGRHPGGLQFQMGLCSKRTLRPGAVPCINKNDMSEAEREKSEKRKNQKLVAELLEEAEAREAAEASGAITIAPDFVRNTGIVSVPDFVSATGNAFVPFTEKEEEPTEKDPLADEQVETDKSTKSIKKQNCRTCSRPFVVDEKAKDLANEENAVVLYHIEVITGIWISCKEEIARFMCSTCVDNLRTAIEFRETCIRTELQLTIGGDDEQPDDIKENDMELDDKDDHSFNDDIKEEEFISVFPADGENGQTTVESLSRSMNKKTGQVLHPAAVDPNSLALGAQIYEDLLNEYRGKDKQPRPRQKMAESPKTQQVQRQRKQRPREPAPKRTKRSREEKNRIRREHIRALPLNHVCDQCGASFRVKCNLTIHMLRHSRTKNYTCPECPKQFYDAYMRNMHIRVRHRGELPFACNYCKKAYSSSNMRYLHEKNVHGASPRIHRNVNKLNQRIELRAENQSQANKQPRENVRHSCMYCDKSYATKYALNGHINQHLGLNPFKCKVCGMSFPSPQSKKKHEMRHDSKRPFECDICLKGFYTRSKLKEHERIHTGERPYRCDICDAFFRYKFNLYSHQFSKMHKENLQKAQTDPIVEDSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00608725;
90% Identity: iTF_00608725;
80% Identity: -