Basic Information

Insect: Drosophila neotestacea
Gene Symbol: grau
Assembly: GCA_035044365.1
Location: JAWNMD010000155.1:1959149-1961280[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.025 1.9 9.3 1.1 6 23 288 305 288 305 0.98

2 9 5.3e-05 0.0041 17.7 2.9 1 23 311 334 311 334 0.93

3 9 0.00016 0.013 16.1 2.3 1 23 342 364 342 364 0.97

4 9 0.00052 0.04 14.6 0.0 2 23 370 392 369 392 0.96

5 9 0.31 23 5.9 0.2 2 23 398 419 397 419 0.95

6 9 3 2.3e+02 2.7 3.9 2 23 428 449 427 449 0.90

7 9 0.00029 0.022 15.4 0.2 2 23 457 479 456 479 0.96

8 9 2e-05 0.0015 19.1 0.4 3 23 487 507 486 507 0.98

9 9 0.00064 0.049 14.3 8.5 1 23 513 536 513 536 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.025	1.9	9.3	1.1	6	23	288	305	288	305	0.98
2	9	5.3e-05	0.0041	17.7	2.9	1	23	311	334	311	334	0.93
3	9	0.00016	0.013	16.1	2.3	1	23	342	364	342	364	0.97
4	9	0.00052	0.04	14.6	0.0	2	23	370	392	369	392	0.96
5	9	0.31	23	5.9	0.2	2	23	398	419	397	419	0.95
6	9	3	2.3e+02	2.7	3.9	2	23	428	449	427	449	0.90
7	9	0.00029	0.022	15.4	0.2	2	23	457	479	456	479	0.96
8	9	2e-05	0.0015	19.1	0.4	3	23	487	507	486	507	0.98
9	9	0.00064	0.049	14.3	8.5	1	23	513	536	513	536	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTCTGTGCCTAAACAGCGCCAACGACACCATACAGCTTTTCGAGGGCGTTGGCTTGTCCCTAAACGTTGCTACAGTGTTGGCCAAATATTTCTGGTTCCAGCCAAAAAACGATGATCCAATATCGACGGAAATTTGTGTGGCCTGCTGGACACGCGTTAGCGACTTTAACGAGTTCTATTGTAGCGTTGAGAAGGCACATCGCTTGCTCACTGAACGTTTCTCCCTGAAAGGCGGCGAGCAGCAGGAGAAAAGTTTCACTGGAGGTGCACAGAAGCAGGAGCAAGAGCAACTGGATAAGGAACAGTTGGAGGCATCAAAAGAGATTCTGGAAAGCAGCGGGCATGAAAGCGATCAGGACCAGGACGATGATAATGTTATGGAGGCTTTCTATGCCAGCGAGGATGAAACAGCTGCATCCTTTAGCAATGAACAGTTCCTCAATGATGTGCTGGCCCAGCAAGAAGATGAGGAACCTCCCAACGAGCGGGAGGAGCTCATTGTCAAGCAGGAAATCGGAGTTATAGAGGTTCAAGAACGTCGAGAGACACGTGCCACACGTGCCAAAAGCAAAGCGAATCAATTGCTTGCTTCTAAGTCTCCTCCAGCTGAAAAGCCCACACCTGCCAAGCGCAGGGTAAGATCAAAGTCTGAAAAGCCCGACGCCAGTGTCGAAGAAGGAACAAAGAACAAACGTTATGTGGATTATAAGAAATCCATGTGGGAAATTGATGAGAAGATAGCACAACATATGCGTCTCACCTGTAGCATTTGCCACGAGGGTCAGGAGACGTTCCTGTTGCTTTGCAAGCACATGCAGCAAGTGCATCATCGTAAGGGTTACGCTGTGTGTTGCAACAAGAAGTTCTACAAGCGATCCTTTCTGACCGATCACATAGATCGTCATGCCAATCCTGAGAAATTTAAATGCAATCTCTGTGGCAGAACCTTTGCGGATAAGCAATGTCTGCGGAATCATGAGCTTCTGAAGCATCAGCCGGATGAGGAAAAAACATTCATGTGTGAGCACTGTCCTAAGCGATATACCAAACAGTATTTATTGGATCAGCATAGGATTATACACAAGGAGCGGAATGTGCCCTGCGATATCTGCGACAGGCGTTTTCCCAACATTTCCATGCTCGGTACGCATGTGAAAATGGTCCATGGCAATTATGGCACAATGTGCGATATATGTGCCCAGGTGATAAGAGGACACGCTGCCTTTCAACGCCATCAGCTGGAGCACGCAGGGATTACAGAGCCCAAGGTTCAGTGTGACATTTGTGGATCGTGGCACAAGAACAAATACAGCTTAAAGAAGCACGTGAGTCGACACAATGGGAACTCGGAGGAGAGCACCTGCAACATTTGTGGCAAGATATCGCCAAATCGCAGTGCCATGTTGAGTCATCAACGATATGTGCATACTGCGGATCGTGTTCATGGCTGCAGTGTGTGCAACAAGAAGTTTAAAAAAGCCATCAATCTAAAAGAGCACATGGCTATTCATACGGGTGAAGTGCTCTACAAGTGTCCACATTGTCCCAAGACTTTCAACTCGAATGCCAATCAACATTCTCATAGGAAGAAGTGCCATCCCAAGGAGTTTGAAGAGGCACGTAAGGCGCGTCTACAGAATCGCATGGCACCGTCTGGAGGTGAAAGTAAAGCCAAGGCTAACATGATTACAATAACCACACCTGGTGACACCGATGGCGAAGTGGAGACGCATAACATTCTGGTAACAACGACGGAACAAAGCGACGAGGAGGATTTCAAAGGCGAGGACATTGAGTTTATGCTCACACTCAGTCCACAGCCAACGGAATAG
Protein Sequence: MICRLCLNSANDTIQLFEGVGLSLNVATVLAKYFWFQPKNDDPISTEICVACWTRVSDFNEFYCSVEKAHRLLTERFSLKGGEQQEKSFTGGAQKQEQEQLDKEQLEASKEILESSGHESDQDQDDDNVMEAFYASEDETAASFSNEQFLNDVLAQQEDEEPPNEREELIVKQEIGVIEVQERRETRATRAKSKANQLLASKSPPAEKPTPAKRRVRSKSEKPDASVEEGTKNKRYVDYKKSMWEIDEKIAQHMRLTCSICHEGQETFLLLCKHMQQVHHRKGYAVCCNKKFYKRSFLTDHIDRHANPEKFKCNLCGRTFADKQCLRNHELLKHQPDEEKTFMCEHCPKRYTKQYLLDQHRIIHKERNVPCDICDRRFPNISMLGTHVKMVHGNYGTMCDICAQVIRGHAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVSRHNGNSEESTCNICGKISPNRSAMLSHQRYVHTADRVHGCSVCNKKFKKAINLKEHMAIHTGEVLYKCPHCPKTFNSNANQHSHRKKCHPKEFEEARKARLQNRMAPSGGESKAKANMITITTPGDTDGEVETHNILVTTTEQSDEEDFKGEDIEFMLTLSPQPTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602095;
90% Identity: iTF_00608704;
80% Identity: -