Basic Information

Insect: Drosophila neotestacea
Gene Symbol: ken1
Assembly: GCA_035044365.1
Location: JAWNMD010000151.1:675190-677439[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.087 6.6 7.6 7.0 2 23 228 249 227 249 0.96

2 12 6.2e-05 0.0047 17.5 1.2 1 23 255 280 255 280 0.95

3 12 0.00051 0.039 14.6 0.4 3 23 289 312 287 312 0.93

4 12 0.00049 0.038 14.6 5.1 1 23 322 344 322 344 0.97

5 12 0.00038 0.029 15.0 1.8 2 23 352 373 351 373 0.96

6 12 0.0069 0.53 11.0 0.5 1 23 379 401 379 401 0.97

7 12 0.028 2.1 9.1 1.9 1 23 407 430 407 430 0.97

8 12 0.018 1.4 9.7 4.1 1 23 436 458 436 458 0.95

9 12 0.02 1.5 9.6 2.5 2 23 465 486 464 486 0.95

10 12 0.00017 0.013 16.1 0.8 1 23 576 599 576 599 0.96

11 12 0.0092 0.7 10.7 3.1 1 23 605 627 605 627 0.95

12 12 8.8e-05 0.0067 17.0 3.6 3 23 635 655 633 655 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.087	6.6	7.6	7.0	2	23	228	249	227	249	0.96
2	12	6.2e-05	0.0047	17.5	1.2	1	23	255	280	255	280	0.95
3	12	0.00051	0.039	14.6	0.4	3	23	289	312	287	312	0.93
4	12	0.00049	0.038	14.6	5.1	1	23	322	344	322	344	0.97
5	12	0.00038	0.029	15.0	1.8	2	23	352	373	351	373	0.96
6	12	0.0069	0.53	11.0	0.5	1	23	379	401	379	401	0.97
7	12	0.028	2.1	9.1	1.9	1	23	407	430	407	430	0.97
8	12	0.018	1.4	9.7	4.1	1	23	436	458	436	458	0.95
9	12	0.02	1.5	9.6	2.5	2	23	465	486	464	486	0.95
10	12	0.00017	0.013	16.1	0.8	1	23	576	599	576	599	0.96
11	12	0.0092	0.7	10.7	3.1	1	23	605	627	605	627	0.95
12	12	8.8e-05	0.0067	17.0	3.6	3	23	635	655	633	655	0.95

Sequence Information

Coding Sequence: ATGGATGAGGAGGGGACTCCAGCCTCCATACACACAGTATGTCGCACTTGTTTAACAAACTTGGAAAATGCTGCAGTTTTTGACCTGTTCATTATTCCGGGCCTGGCCAAGAAACTGTGTGTATGCACCTCCCTCTCAGTGGAGCACCAGGATGGATTTCCGAGAAATCTCTGCACCACCTGCTATAGCCGCCTTGACGATTTGCATGACTTTCAAAAGCAATGCGTGGAATCTGTGGAAAAGTTCAAGGAGTTGGTGGTCAAGAACAACTTTTCAATTCAGACAAATCCTCTGGATAACTTTGACATGTTAAATGTTCCCCCTCAGGATGCAGAGATTCCCGATCCACTACTAAGCAGCAAAATAGAAATTGAGAATGAGCAAGATGTGTTTAAGATGTTGGAAGATGTTGACAAGGAAGTCGAGCAAGTAGAGAATGAGGACGATGAAGATAaaagcgacaacgacaatgaaGATATGGACTTCTTACTAGATAGCAGCGATTCCGATGATGAGATGCCGCTGTCACGCCTACAAAGTaatacaagaacaacaaggaCAAAGACCAAAAATAATGACAAAGAGCAGGAATCGTCGGAATCGGATGATGAGGACGAGACTAAGTCAAAACCGAAACGTAAGCGAATTCCAGCAGCTGAGCGACATTTGCACCGCATCCTTGAATGTCACATTTGTCATCAGAAGTTCAAGAAGGAAATTCGCTTTGAGGAGCACATGAAACACCACAATGATCAATTGCCATTTCAGTGTACAGTTGAGATCTGTAAGAAGGGCTTTACAACTGCTGCAGGACTGCGTCATCATATGGATCATGCCCACCCAGAACTCTGTAatcttataccctgtacagtCGAGGGATGCGATGAATCATTCCCTCGAACTCGCATGCTCACACACCACTTAAAGAAggttcataaaatattaaagcctGAGATCCGTAGTCATTCGTGTACCGAATGCGACAAAGTTTTCCGTTGTCCAACGGCGCTCAagaaacatatgtataagcaCACTGGTGAGGAGCCTCCAATATCATGTAACATCTGCCAGAAACGCTTTCACATTAACAGCGAACTTCGAGATCATCTCTTACGGCATGCTGGCGTCAAGAATCATGTGTGTCCCTACTGTGGAGTGGGCAAGACAACGCGTCAGGAGTGGAACAAACACATATTAACGCACACCAGAGAGAAGCAGTTCCAGTGTCGTCAATGCGATCATGCCTCCCACAACAAACAGGCTCTGGCCAATCATGTCAAGGTGGTCCACATGAAAATCAAGAACTTTGCCTGTCAATATTGTGGCAAGACCTTTGGCAAGTCGCATGCCTGCAAGATCCACGAGAGACTTCACACTGGAGAGAACTGTTGCGTATGTAAGATCTGTGGCAAGATCTTCCTCTTCGAGAAGAGATTGACCAAGCATTTGCAGCTTCATGAGAAGCGCGACGTACCGCCGCCTTCAACAGCTGATAAACCCCAAGTTGATGAACAGAGCACTTCCAATGTGAGCCAGGAGCAAAGTCATCTGACAGAGCCGGTAGATGTAAAGCTCTTGCCCGCGGTTCCTCCCAAGCCCAAGAACTCCCATCGTGTGGAGCGTGTGGATATATCTCAGCTTGCAGGAACATCTGTTAATCCGATATCATCTGTTTCGGTTCCATCCTGGTCGCCACAGGTCAACTTTACCAAGAAGGAAGGCCAGCATATTTGTCCAGGTTGTGGACGCGGTTTCAATCACATTGGCAACATGAAACTCCACTATAAAGTTATACACGAAAAGATTAAGGACTTTGCTTGCCGCTTCTGCCCTAAACGTTTTGGCAAGGCTCAATATCTGCGGCATCATGAGTATACACACACGGGGGAAAGGCCATACGGCTGTAAAATATGCGATAAGCATTTTAATCATGAGTCCTCATTAAGGAAGCATACGATCGCCCACAACAGACCTCCAAAAGTGCCAAAGGCTCCAAAACCTCCGCCCAAGACAAAAGAGCAgaggccaaaaataaaactgaataagCAACCAGCAATAAATTTCGAACAGTTTAAAGATCCAGCTGCAGAAAGAGCAGCTGCAACGGCTGCTCTAATCGCCCAACAGCGGGACGAAATTGAGGCCAAGCGCAAGGCGGAAGCTAAAGCTCGGGAAATTCAAGAAGCAGCGTGTGAGCAGCTCCAGAaattacagcagcaacagactTCCTATGATAGCTTCGCTGATTGA
Protein Sequence: MDEEGTPASIHTVCRTCLTNLENAAVFDLFIIPGLAKKLCVCTSLSVEHQDGFPRNLCTTCYSRLDDLHDFQKQCVESVEKFKELVVKNNFSIQTNPLDNFDMLNVPPQDAEIPDPLLSSKIEIENEQDVFKMLEDVDKEVEQVENEDDEDKSDNDNEDMDFLLDSSDSDDEMPLSRLQSNTRTTRTKTKNNDKEQESSESDDEDETKSKPKRKRIPAAERHLHRILECHICHQKFKKEIRFEEHMKHHNDQLPFQCTVEICKKGFTTAAGLRHHMDHAHPELCNLIPCTVEGCDESFPRTRMLTHHLKKVHKILKPEIRSHSCTECDKVFRCPTALKKHMYKHTGEEPPISCNICQKRFHINSELRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHASHNKQALANHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCVCKICGKIFLFEKRLTKHLQLHEKRDVPPPSTADKPQVDEQSTSNVSQEQSHLTEPVDVKLLPAVPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKVIHEKIKDFACRFCPKRFGKAQYLRHHEYTHTGERPYGCKICDKHFNHESSLRKHTIAHNRPPKVPKAPKPPPKTKEQRPKIKLNKQPAINFEQFKDPAAERAAATAALIAQQRDEIEAKRKAEAKAREIQEAACEQLQKLQQQQTSYDSFAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507084;
90% Identity: iTF_00608666; iTF_00583892;
80% Identity: -