Basic Information

Insect: Drosophila neotestacea
Gene Symbol: -
Assembly: GCA_035044365.1
Location: JAWNMD010000151.1:666606-668864[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.036 2.8 8.8 6.7 3 23 228 248 226 248 0.97

2 12 0.0008 0.061 14.0 4.4 1 23 254 279 254 279 0.95

3 12 4.2e-05 0.0032 18.0 0.9 1 23 286 311 286 311 0.95

4 12 0.0017 0.13 13.0 3.5 1 23 319 341 319 341 0.97

5 12 9.4e-05 0.0072 16.9 1.0 3 23 350 370 348 370 0.98

6 12 0.00016 0.013 16.1 0.2 1 23 376 398 376 398 0.98

7 12 0.43 33 5.4 6.5 1 23 404 427 404 427 0.95

8 12 0.066 5 8.0 8.9 1 23 433 455 433 455 0.95

9 12 0.00011 0.0083 16.7 2.1 1 23 461 483 461 483 0.99

10 12 2.2e-06 0.00017 22.1 0.3 2 23 564 586 563 586 0.96

11 12 0.00022 0.017 15.7 5.0 1 23 592 614 592 614 0.97

12 12 0.0018 0.14 12.9 5.6 1 20 620 639 620 642 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.036	2.8	8.8	6.7	3	23	228	248	226	248	0.97
2	12	0.0008	0.061	14.0	4.4	1	23	254	279	254	279	0.95
3	12	4.2e-05	0.0032	18.0	0.9	1	23	286	311	286	311	0.95
4	12	0.0017	0.13	13.0	3.5	1	23	319	341	319	341	0.97
5	12	9.4e-05	0.0072	16.9	1.0	3	23	350	370	348	370	0.98
6	12	0.00016	0.013	16.1	0.2	1	23	376	398	376	398	0.98
7	12	0.43	33	5.4	6.5	1	23	404	427	404	427	0.95
8	12	0.066	5	8.0	8.9	1	23	433	455	433	455	0.95
9	12	0.00011	0.0083	16.7	2.1	1	23	461	483	461	483	0.99
10	12	2.2e-06	0.00017	22.1	0.3	2	23	564	586	563	586	0.96
11	12	0.00022	0.017	15.7	5.0	1	23	592	614	592	614	0.97
12	12	0.0018	0.14	12.9	5.6	1	20	620	639	620	642	0.95

Sequence Information

Coding Sequence: ATGAACGAGGATACTCCAGCCTCAATACACTCGGTCTGTCGGACTTGTTTATCCAGTCTGCAACTAGGCGACGCTTTCGATCTGTTTATGGTTCCGGGGCTGGCCAAgaaactgtgtgtgtgtacttccCTTTCGGTGGAGCACCAGGATGGATTTCCGAGAAACCTCTGCACCGCCTGCTACAGTCGCCTTAACGATTTGCATGACTTTCAAAAGCAATGCGTGGAATCTGTGGAAAAGTTCAAGGAGTTGTTGTCCACCAATTGCTTCATTATCCGAACAATTGCAGAGGAGGACCCTTCCGCTTTGAATGTATCTGCACACGATGAAGGGGAGCATATCAACTTTGATCCACTGCTGAATACAAAAGTAGAAATTGATAACGAGGAGgatgtttttaaaatgattgaaGACGTCGATAAAGAATCTGAAAATGTAGATAATTTGGAGGATGCATTCAACGACAGCGAGAGCGACTTTAACAATGATGATGCGGACTTCCAAGTAGATAGCAGTGATTCTGATGATGAGATGCCGCTGTCAAGCTTTCAACGTAATCCCAGAGCAGCAAAGACCAAAACCATAAGTAATGAAAAAGGGAAGGACAAAGATGAACCTAAACAAAAACCTAAGCGTAAACGGATTCCAGCAGCTGAGCGGGATCGTCATCGGTTAATTGATTGTCACATTTGTCATCAGAAGTTCAAGAAGGCATTATGTTATGAGGAGCACATGAAACGGCACAATGATCAATTGCCATTTAAGTGTACAGTGAAGAAGTGTCAGAGGGGATTTACGACTTCTACTGGATTGAAACATCATATGGAACATGCACACACAGAACTCTGCGATCAACACCCTTGTACAGTTGAAGGATGCAACGAATCCTTTGCGCAAACTCGCATGCTTACAAAACATATGAGAAAGGTACATAATATTGCGAAACCTGATATTCATCCATGTTCGGAGTGCGAGAAAGTATTCCGTTGTCCAATGGCACTCAAGAAACACATGTATAAACACACTGGAGAGGAGCTGCCGTTCGGATGTACTATCTGCCAGAAACGTTTTCGGGTTAACACAGAACTGCGGGATCATCTTTTGCGCCATGCCGGGATCAGGAACTTTATGTGTCCGTATTGTGGGGTTGGCAGGACAACTAAACAAGAGTTGGACAAGCACATATTAACTCATACGAAGGAAAAGAAATTTTTGTGTGATCAGTGTGATCATACTTCTCACAACAAGCAATGTATGACCAAGCACATTAGGGTGGTGCACATGAAGATCAGGGATCATATGTGCCAGTATTGCCAAAAGTCCTTTTCCAGCGCTTATCACTGCAAGAACCACGAGAAACTGCATACTCGGGATGAGTGTTTCGAGTGCAAAATCTGTGGAAGAAAATTCCTCTTTGAGAGTAGattaacaaaacatttaaGGACTCATGCGAAAAGCGGAAGTAAATCGACTGCGGACGCTGCAGAGACGGAACTTGATCAAGATGAACAGAAGGAATTGATAGAACCTGTAAAAGTACCAGAAGTTCCTGCCAAGCCGAGGGATCCCCGTCGAATTGAGATTGTGGATATTTCTCAATTGGCTGGAACCTCCGTCAATCCCATTCCTTCGGTATCTTTATCATCCTGGTCGCCACAAGAGAACTTCACCAAAAACGAAGGCCAGCTCACTTGTCCGGAATGTGGTCGAGGCTTCAACCACGCTAGTAATATGAGACTTCACATAAAGGTTGTACATGAAAAGGTCAAAGACTATGTGTGTCGCTTCTGTCCCAAGCGCTTTAGCAGATCTCAATATCTCCGGCATCATGAGTATACACATACGGGAGAAAAACCATACGAGTGCAAGGTATGCAAAAAGCACTTTGCTCACGATGGCACATTAAGAAGGCATATGGAATGTCACGACAAACCTCCGAAGGAACACAAAATTCCCAAGGCCATGTTTAAAGATCCTCAGGAGCCTAGACTGAAACTCAACACAGAGCCAATAATGAATTATGAACAGTATCAAGATCCAGATGCAGAGCGGGATGCTGCAACTGCTGAATTGGTGGCCAAACAACTCAGCCGCGATGATAGTGATTCCAAGCCCAAATGGGGTCTAGCCAAAGGTCAGGAGGTTCAAGCGGCAGCCTACAAGCAACTTCAAGCGTTGCGGGacaaaaaacatgaaaagaTTTCCTATGATAGCTTAAAATCTGATATAAGCCAGGATGTTCTCAATAATCATGTATAA
Protein Sequence: MNEDTPASIHSVCRTCLSSLQLGDAFDLFMVPGLAKKLCVCTSLSVEHQDGFPRNLCTACYSRLNDLHDFQKQCVESVEKFKELLSTNCFIIRTIAEEDPSALNVSAHDEGEHINFDPLLNTKVEIDNEEDVFKMIEDVDKESENVDNLEDAFNDSESDFNNDDADFQVDSSDSDDEMPLSSFQRNPRAAKTKTISNEKGKDKDEPKQKPKRKRIPAAERDRHRLIDCHICHQKFKKALCYEEHMKRHNDQLPFKCTVKKCQRGFTTSTGLKHHMEHAHTELCDQHPCTVEGCNESFAQTRMLTKHMRKVHNIAKPDIHPCSECEKVFRCPMALKKHMYKHTGEELPFGCTICQKRFRVNTELRDHLLRHAGIRNFMCPYCGVGRTTKQELDKHILTHTKEKKFLCDQCDHTSHNKQCMTKHIRVVHMKIRDHMCQYCQKSFSSAYHCKNHEKLHTRDECFECKICGRKFLFESRLTKHLRTHAKSGSKSTADAAETELDQDEQKELIEPVKVPEVPAKPRDPRRIEIVDISQLAGTSVNPIPSVSLSSWSPQENFTKNEGQLTCPECGRGFNHASNMRLHIKVVHEKVKDYVCRFCPKRFSRSQYLRHHEYTHTGEKPYECKVCKKHFAHDGTLRRHMECHDKPPKEHKIPKAMFKDPQEPRLKLNTEPIMNYEQYQDPDAERDAATAELVAKQLSRDDSDSKPKWGLAKGQEVQAAAYKQLQALRDKKHEKISYDSLKSDISQDVLNNHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00608624;
90% Identity: iTF_00608624;
80% Identity: -