Dneo014588.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila neotestacea
Gene Symbol
hang
Assembly
GCA_035044365.1
Location
JAWNMD010000535.1:251118-264510[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.36 28 5.6 1.0 3 23 453 474 452 474 0.93
2 18 0.26 20 6.1 3.5 3 22 581 600 579 600 0.89
3 18 0.00078 0.059 14.0 3.3 1 22 709 730 709 732 0.90
4 18 0.089 6.8 7.5 0.1 2 21 744 763 743 764 0.93
5 18 0.0009 0.069 13.8 0.2 2 23 909 931 908 931 0.95
6 18 0.0026 0.2 12.4 0.1 1 23 939 962 939 962 0.96
7 18 2.1e-05 0.0016 19.0 0.1 2 23 1048 1069 1047 1069 0.97
8 18 0.00037 0.028 15.0 2.9 2 23 1190 1212 1189 1212 0.97
9 18 0.029 2.2 9.1 0.2 2 23 1221 1243 1220 1243 0.95
10 18 0.0001 0.0077 16.8 0.4 1 23 1256 1279 1256 1279 0.97
11 18 0.00016 0.012 16.2 1.1 1 23 1334 1356 1334 1356 0.99
12 18 0.0025 0.19 12.4 0.9 1 23 1364 1387 1364 1387 0.96
13 18 0.088 6.7 7.6 0.4 2 19 1395 1412 1395 1413 0.94
14 18 9.3e-05 0.0071 16.9 0.4 3 23 1518 1538 1517 1538 0.98
15 18 0.0065 0.5 11.1 0.1 1 23 1573 1595 1573 1595 0.97
16 18 0.00077 0.059 14.0 0.6 2 23 1683 1705 1682 1705 0.93
17 18 0.0083 0.63 10.8 0.3 3 23 1761 1781 1761 1781 0.98
18 18 8.7e-05 0.0067 17.0 2.1 1 23 2167 2189 2167 2189 0.99

Sequence Information

Coding Sequence
ATGATCACACCATTGGATCAGCTGTCAGTGTATATTTGCCATGCTTGCATCAGCTATTTGAACTCTTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCCCAATCGAAGCAACGTCAATGGCTGGACACGGACAGAACCAAACAGCAGACACTATTGGGCTATTTGGATTTGAATCGAGCCGAGAATGGCAGCATCGTTgaccaacaactacaacagcagcagcaatccgAGTTGAAAATCGATACGGCAACGTCTGCAGCTGAGAAGACATCGGCCTCCAACATTTTGGATGGCATACCCTCGCTGAAGAAGCGCAAATCGTTAACAGTCTATGTGAGTCCCAAGCAACAGCttcaacagcaccaacaacaacagcttcaacagcaacatcagcagcaacaacagcatctaTTGCAATCGGCAACGGAGCCACAGCAAACATTGCAGAATCTTTTATTGCAGGTGCCCTCAACGGCAGCAATGGCAACGATATcatcacaacagcaacagcagcagcagcaacaacgcaaatatcagcagcagcaacaacgtggcaagcagcagcaacaacagcaacaacatcaccatcatcatcaacagcaacaacaacaacaacagtcacaaCATCACTATCATCATTCACAGCAGCGACATAGACGCATTCGTCAGCCACGACGACAACAGGTGCAACaggcagcaactgttgttcAGCGTTTGCCCAAATTTAAGCCAAAAGTATATTTGCCACTTGACATTGCAGTGCCACCGCTGCCACCAATGGTGTTGCCAACGCTAACGCcaagtgttgctgttgctgctgctagtgctgctgctgctgctggtggtggtgttgctgAGGCAGCTGCAACATTGCCAACGTTGCCATTGCAACCAATTGATTTCAGCCAGTTTAAGAATTCAAATCAGAGTCAGAGATATGGCAGCGTCTTGCCACCGCCGACACCAGTTGCAACAATGACCAGCAACattgatgctgctgcttctgcatCTGCGTCTGTCACTGCAACCTCAGtcactgcaactgcaactgcaaccgcAACTGCTGCAGTCACGACTCCGCTTCTAATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCATTGGATGACACCGACGATGACTTTCAGATGAAGTGCATTGACGAGTCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGGCCTCCGACTATGATTATACGGCGCAACATGGTGTGACGGCGGCTGTGGCAGCAGCATCGCTGCCGGCAAGCGCTGTGGCAAATGTGGCAGCCGCAGGAGACTCCAAGGTGGCAAGTTGTCGTGCCTGCAGTCTACAGTTCTCGACCCGAGCAAATGCCCGACGACATGAACGGAATTTACATCCGAATCTGTTTCAATTATCGACAGACTCACCAAATAATACGCCAATCACAAAACCAACTCCGGCACTAGCCGCTGCACTCGAAATTCAACGTGCTGccgcggcggcagcagcaacagcggaGGCAACGAAAGCAGCTGCCGGTGGCAATATTTCGACACAAAAGTATCGTCAGGTGGTAATGAATACGTTCATCAAGTGTGAAAACGGTGGCTATGACTATGACAATCCGGAGCAATATCAGCAATTGTTGAGTCGCGACAAAGTCGAGTTCATACAGGAAAATAACGAATTTTTGGAACAATATCAGACGATGACATGTCGGTGTTGCAACAAGTTCTTTAGCACCTATAAGAATTTTATGGCACATGTGCGTAAAAAGTATCCATTGTTGCCACGTAATTTGTGCTTCAATTGCCTCAAGATGAACGATTCGAAGGCGTTGTTTATATCGCATCTGAAGAAACGCAATTGTATTAACTTGTATCGTGTGTTGAACGCATTGCGTCTTAAGCAACCAAATTTTGCACATGCCACAGCATCCGGTGTGGTTGCAACAAccgagcagcagcaacagttggtgGTAACAGCACATGagacaacagcagctggaacaacaacaacaacagcaacatcatcatcaacaacaacaacagagcgTCCAGAAAAGTTGCGTGCCAAAGAGTTGCTAGTGAATAAACTATATGAATGTAAACTATGTCCAAAGGGATTTCGAACAAAGCACGAATTTCGCACCCATGTCTATGATAAACATGCGGATGTCCAGCGCAAGGATAACAATTCCATACAGTGTAGTTTCTGTGGTTTGGATTTTGCTGATCCCGTGGATCGACGACGTCATTACAATAATATGGATTGCATTGTCCGTTTACGTTGCATGACCTGTGATGCCAAATTGGAGACACATCAGCGATTCCTTGATCATGTCTATCAGGATCATTTGGGCGGTGTGAGCAGTGACAATGcatcgacaacagcaacagccaatAGTGGCATTGATCATTCCCCACCAACAAGCAAACGGAGTCTTCTCGGTGCCCTTGGCATTGGTGTCAATCAATGTCAATCCTCCAATGATGAATCCCACAGTAGCAGcaccaataataataacaacacatCAACACCATTAACCTCAACACCAAAACtatcaacatcagcagcagctgcagctgcagcggcagcTGGAGCAAgcggaggtggtggtggtggtgctgctgcaaCAAGTGGAGGTTCCAATCGTGGGGATGCCCCTAAATCGCAGTATTTCTCACGAATGCCACAGGTTTGCCCCATTTGTGGGCAACagtacaacaactacaacaacgtGTTGCGTCATATGGAATCGAAGCATCCAAATAAATTGCCCGAAACATATAAATGTGTTCGATGCGGCTTGGGCTATCCAAGGATCTCATATCTGCGCGAGCATATGATCAATGTTCATGGCGTGGACAAGAATCGTCATTCGGGCGGCTTTGAATACATTGTGAATGCGGATGCGGTTAAATTGGCCGATGGCAGTACTCCAAATGTCTATACCGGACGATATGATTATGTGATGAAGGATTTGATGTCCATAACAAATGGTGGGACACTCgatgatgatgaggaggaaGGCGGCAGCATTGCCAAAAAGATGCGACTGGATgacagcagtaacaacagcagcattaaCACAAGCATCGCCAATCAGCAAAAGGAGTGTCCCATTTGTAATGCCGTGTTTAGCAATAATATTGGTTTATCAAATCATATGCGATCACATTACACGGCCTCAtcgacagcaacaaatgcagcATTGGCAGCTGCAAATCGAATGACTCCAAAATCGTtgacaataacagcaacaccGCCACTTGAGTTgtcaacaactgcaacagcagcagcagcaacaacgtcgGCAACAACATGTTCTTCCTCCACAAGCAGCACAGCAGcggcaactacaacaactgcagcggcaacggcaacagcaagtGCTTCAACATCGACGACAACCGGAGCAggaacagctgcaacaacgaTTACCAAAGTGCCACCGGCAATGGTTAATCAAACACCACAGGAACAAGCCGTATTCCGTCGAAGTTTAGATCAAGCCGCTGATCGTCGCTTTCGTCGGATGCGTTGTCGCATTTGTCAGCGCAGATTTAGCTCAAAGAAATCATATCGTTATCACATGTTGACCGATCATCAGGTGCAAAATGTTCAGtttatcaaatgcaaattgtgtaATGCTGAATTTGCATACGAGAAGGGACTGAAGGTGCATCTGTTTAAGGTGCATGGACGTGTCATTAAAGATGAGATGATtatcaaacaatttgaatgTGATATCTGTTCGACTGTCTACAGCTCCCAGATGGAGTTGCAACAACACAAGCGCAGTGTACACAAATCCCAATTGGGCAGCAGCACAGATTCTGCAATGAAATCATCAAtgaaatcatcatcattattatcatctaCATTTACCGCTAACGCTACCGCTACCTCTTCTCTTGACCTGGCCGAAACATCCGGCAGTGCATCGATGGCTGTGTTGCCACTTTATTGGTATCAGTGCAAGTATTGTCCATCCAATTTCAATACAAACAAGAAACTTGCCATTCACATCAATTCGCATGATGAGTTCGACTCCAATGATTATTCCTGCAAGGATTGCGGCAATGTCTACAGCGGACGTAAAAGTCTCTGGGTGCATCGGTATAAAAAGCATCCGCAGGTTCCGGATCCGGCGGAGTGCACTCTGTGCCGTAAGATGTTCTTTGATCGCCAGATGCTGGAGAATCATACGCCTACCTGCAATCGCAAACCCATTACGGCAACGGGTGCACATCAACaggatcaacaacaacagcaccagcagcaacaacagcatcaacagttgcagctgcaacatcagCGTGGAATTTTTAAGCACAAAACGggcgatgatgacgatgaggatgaggatgatgagcaacagcagcagcagcagcaacacttgcTGTTGGATGGTGGCGTCGGCAATGTGGCCAGTGATGGCAGCAATGCTGATAGCAACACTATTGCAGTTGCAAACACAATTAGTACAAGCAGCTTAAAGATACGCATACCAGAGGTGGCATGCACCATTTGTGGGGCACGTTTCACCGATCAAGAGATGTTCAGCAAGCACATCCAAAAGCATGAACAAGAATTGTATGTCGACAATCCATTGGCCGCCATGTTCGATGATGGTCCAGCGGATGCTGGACAATTTCAGGTGGAGCGACAAAATGAGAATGGGGAATATGCATGCGATTTGTGTGCCAAGACATTTCCCCAAGTGATTGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCTCATCATCGACGGCGAAGCGACAATgctgaacaacaacatcaacaacagcagcaacaacaacagcaattcgATGTTGCATCTACGCGAATTGCATGCGGTGGGTCTGATGCccaatcagcaacaacatcagaagcagcagcagcagcaacaacaacagcaacagcaatcgaacagcagcaacaacaacagcaacagctcgTCGACCAGCAAATCGTTGAAACGTAAACGTGAATTGAAATGTGAATATTGCGCCTCAACATtcattagcaacaacaatctgcGTCGCCACATGTACGAGTTGCACAAACATGAGGTTAGCAATCTTCCCGAACCGCCAATAATTGAAGTAGATGAACCATTGTGTTGTCGCCGTTGCGGTgatattaagtttaaaactaaagaattGTGGATTGAACACAAATTGGCCGATGCCAAAGTGGTTCGTCCATTTTGTCCATTCCAATGGGGCTGTGATCTTTGTGGCGAGTATTTGTCACGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGAGGTGATTGTGCCAGTTGCCACCGCCCAAAAAACGATAGCAACTACCAagaacacaacagcaacaactcaaGCCACAAGcacagcagcggcagcggcagcggcaacaacgaaggcaggaacagcagcagcagcagcagcaactgtaacaacatcgacaacaactgcaactgcaacaacagctaaagcGTTAAAAGTCAAACAATTGGCGGAAGAGAGTGAGGAGGTAAAattaaagcaggaagaagaGAATGAAAGTGATATGGATGATGATAGTGACAgcgatgataatgatgatgaggatgatgatgacgatgatgatgaggatagCACAAGTGCTGATGATGAGGATGGCGATGATGATGTCGAGGATGAAGATgacgatgaagatgatgaagGTGAAGGTGAAGATGTTgttgcacagcagcagcagcaacagcagcagcaccacaacaacaacagcaatgctATTgacaacgatgatgatgatgatctgATTGAAGAGGTTATTGATGAGATTGATGATGTTGAGGAAGATGACGATGTAAATGTTAATGaacaacatgttgttgttgccacatcaaacaacaacaatagcaaagtGAACTTTGTCAAGTTGAATGGCAATGGTGGCAAGAAGGCAAAGGTGCAACATGTCGTGCATAGCTCTGACGATGAtgaagaagatgatgatgaagatgtgGATgacgaagatgatgatgatgataatgatgtggAAGAAGTGGAAATGGCTGACGAGGTGGAGGAAGTAATGGGTGATGTAATGACCATTGATGATATTATTGAAGAAGACGATgatgacgatgatgatgatgatgatgatgacgacaacaacgacgataACGATGtggatgatgacgatgatgttgatgatgatgttgaagaagaggaggaggaagaagtTATGGATGAAGATGATGTTGGCAATGATCGAAATCGTATTGATGATGATCGTGTCAACACCATTGGCGATGgtacatcatcatcatcatcatccgaGAGtgagtcaacaacaacaacgacaacgaattCGCATTCAACTGGTGAGCGAcgtaaaaaaacaaagaaatcaaatgtAGATTCATCAGCAACACATGGCGTTGCGACTGATCAGTCTAATTCCAGTTATACCTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTGCTGCAGACACACATTAAAAGTCATTTTCTTAATGGGCCAGCGGCGggcagcaaaagcagaagcagcgccagcagcagtagcaatgccagcagcagcaacaacattaacagcaacagcagtagcagtagAGGCAGCAccagccgcaacaacaacaataataataataacaagaataacaaaaatatattgaaaaccaaaaagtCCAGCTTGTTGGTGGAGGCAACAAccacaccaacagcaacagcgacaacaacaacaacagcggctacaacgacgacgacgacaacgccAACAGCGACTGCTGCAGAGGCAGAGGATGCAGCAAGCTTGAACTGA
Protein Sequence
MITPLDQLSVYICHACISYLNSWQSFKNRCLSSQSKQRQWLDTDRTKQQTLLGYLDLNRAENGSIVDQQLQQQQQSELKIDTATSAAEKTSASNILDGIPSLKKRKSLTVYVSPKQQLQQHQQQQLQQQHQQQQQHLLQSATEPQQTLQNLLLQVPSTAAMATISSQQQQQQQQQRKYQQQQQRGKQQQQQQQHHHHHQQQQQQQQSQHHYHHSQQRHRRIRQPRRQQVQQAATVVQRLPKFKPKVYLPLDIAVPPLPPMVLPTLTPSVAVAAASAAAAAGGGVAEAAATLPTLPLQPIDFSQFKNSNQSQRYGSVLPPPTPVATMTSNIDAAASASASVTATSVTATATATATAAVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMASDYDYTAQHGVTAAVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLSRDKVEFIQENNEFLEQYQTMTCRCCNKFFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFAHATASGVVATTEQQQQLVVTAHETTAAGTTTTTATSSSTTTTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTTATANSGIDHSPPTSKRSLLGALGIGVNQCQSSNDESHSSSTNNNNNTSTPLTSTPKLSTSAAAAAAAAAGASGGGGGGAAATSGGSNRGDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEGGSIAKKMRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTATNAALAAANRMTPKSLTITATPPLELSTTATAAAATTSATTCSSSTSSTAAATTTTAAATATASASTSTTTGAGTAATTITKVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRVIKDEMIIKQFECDICSTVYSSQMELQQHKRSVHKSQLGSSTDSAMKSSMKSSSLLSSTFTANATATSSLDLAETSGSASMAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQHQQQQQHQQLQLQHQRGIFKHKTGDDDDEDEDDEQQQQQQQHLLLDGGVGNVASDGSNADSNTIAVANTISTSSLKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATMLNNNINNSSNNNSNSMLHLRELHAVGLMPNQQQHQKQQQQQQQQQQQSNSSNNNSNSSSTSKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPIIEVDEPLCCRRCGDIKFKTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEEVIVPVATAQKTIATTKNTTATTQATSTAAAAAAATTKAGTAAAAAATVTTSTTTATATTAKALKVKQLAEESEEVKLKQEEENESDMDDDSDSDDNDDEDDDDDDDEDSTSADDEDGDDDVEDEDDDEDDEGEGEDVVAQQQQQQQQHHNNNSNAIDNDDDDDLIEEVIDEIDDVEEDDDVNVNEQHVVVATSNNNNSKVNFVKLNGNGGKKAKVQHVVHSSDDDEEDDDEDVDDEDDDDDNDVEEVEMADEVEEVMGDVMTIDDIIEEDDDDDDDDDDDDDNNDDNDVDDDDDVDDDVEEEEEEEVMDEDDVGNDRNRIDDDRVNTIGDGTSSSSSSESESTTTTTTNSHSTGERRKKTKKSNVDSSATHGVATDQSNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPAAGSKSRSSASSSSNASSSNNINSNSSSSRGSTSRNNNNNNNNKNNKNILKTKKSSLLVEATTTPTATATTTTTAATTTTTTTPTATAAEAEDAASLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
iTF_00608595;
80% Identity
-