Basic Information

Insect: Drosophila neoperkinsi
Gene Symbol: BCL11B
Assembly: GCA_037043555.1
Location: JBAMBG010009422.1:9594-11308[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00034 0.025 15.1 0.3 1 23 216 239 216 239 0.96

2 8 3.5e-05 0.0026 18.1 1.1 2 23 261 283 260 283 0.92

3 8 0.00012 0.009 16.4 0.3 2 23 310 330 310 330 0.97

4 8 1.4e-05 0.001 19.4 0.4 1 23 336 358 336 358 0.98

5 8 8.1e-06 0.00059 20.2 0.9 2 23 365 386 364 386 0.97

6 8 9.2e-08 6.7e-06 26.3 1.0 1 23 392 414 392 414 0.98

7 8 0.039 2.8 8.6 1.1 1 21 420 440 420 444 0.87

8 8 0.018 1.3 9.6 0.1 1 23 494 518 494 518 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00034	0.025	15.1	0.3	1	23	216	239	216	239	0.96
2	8	3.5e-05	0.0026	18.1	1.1	2	23	261	283	260	283	0.92
3	8	0.00012	0.009	16.4	0.3	2	23	310	330	310	330	0.97
4	8	1.4e-05	0.001	19.4	0.4	1	23	336	358	336	358	0.98
5	8	8.1e-06	0.00059	20.2	0.9	2	23	365	386	364	386	0.97
6	8	9.2e-08	6.7e-06	26.3	1.0	1	23	392	414	392	414	0.98
7	8	0.039	2.8	8.6	1.1	1	21	420	440	420	444	0.87
8	8	0.018	1.3	9.6	0.1	1	23	494	518	494	518	0.91

Sequence Information

Coding Sequence: ATGGAAAGTATCGAGGAAGAGATTGAGGCACCAGACCAAGTCAATATAAGCGTAAATGCGCAGACTTGTCGCGTTTGCCTGGAGTCCCACGAAACCACATTATGCCTTCGCGATGAAATTGAGTTTAACGACCTGAACTTAgagctgtggcagctgttggAGAACGTATCCAATGTGAAGTGCAACTGGAACGAACCGAATCTACCCACACAGCTGTGCCAGAGCTGCACGCGTCGACTGATCAGTGCCTATGAGTTTATACGCGACGTCGAAAAGTCCAATGAGACGCTACAGGAATTGTGCAGCCATCTGGAGCGGGAGCAATCAGCTGCTACCGttgtgaatgtggatgtggacgAGTATGAGGAACTAGTTCAAGAGGAAGATCATTTCGTGCAGTTGGATGAATGCGAATCCGTCATTGAACTACatgaggaagaggaggaggaggcggaagTGGAGGCGGAGCTGGTACACTCGGAAGAAACAACATGTGAGGAAAAGCCCCTGCTGAACAATAGCAATGACGAACCGAGCGAACTTGTACAAGAAGACTCAGATGCAGAGATAAGTGTTGAGCCCGATCTTTTGGAAGAGCGACCCTCACAGCTGGGCATGCGATTGGCGCACTCCCAAAActatatgtacaaatgtgcCAGTTGTCCACGGAtctttgctaaaaataaatcgctGGCTCGCCACTTTGCCACCGCACACAGGCAAGCGGCAAATGTTGCTGCCCAGGAGCTGGCCAGggagcacagcagcagcggcgcccTCATCTGCGAGCACTGTCCGCGATTATTCAAGCGCCAGGACACACTGCGTCGTCATCTGATTGCATTCCATCCGGAGGTGGTCGCCGCCAGTGGCGATGCCGACGATGTTGCCAGGAGTGTGCCGCCCAAGCGTGCTGCCAAGCGTCGTGAGTGCCCCCATTGTGGCATTAGCTTTCCCGTCTCCAGCCTAACGATACACATACGACGGCATACCGGTGATAATCCGTACAAGTGCGATGTATGCGACAAAGCATTTCCACGCGGCCAGGATCTGAATCTGCACAAGCGCCAACATACCGGCGAGCGTCCGAGCGAATGCAAAATCTGCGCCAAGAAATTCATTTCGCAAAACAAACTGGCGCGCCACATGCGCCTCCACACGGGCCATCGTCCCTACGCCTGTGACAAGTGCGACAAGAGATTTGTGCAGTCCAACGATCTGAAGATTCACATGCGACGGCACACGGGCGAACGACCCTACGCATGTGGTGTTTGCGACAAGAGTTTTGTGTGCGGCTCCCTCTTGAACATTCATCGCAACCAGAAGCGACACCATGAGACTGGGCGGGAGGGCGTGGATTACCTCGATCCTGTTGATCCCTATGAGAACAGTCGCGTGAACAAGCGACGGGCCGAGGACATTGAACGTATGCGACTCCAGCGGGAGGGCGAATCGATGCCACCCATGTTGCTGCGTCCCTACAACTGTGGCATCTGCGGGGATAACTTTAAGAGTGGCGCCTTGCTCACGATTCATCGCAATAAAATGGCCCACTATGAGATCGGCAAGGTGGACTACGGTGATCCCTACGAGCAGCGatacaagcagcagcaacacctaAGAACAGCGCAAAGCGAGGATTAA
Protein Sequence: MESIEEEIEAPDQVNISVNAQTCRVCLESHETTLCLRDEIEFNDLNLELWQLLENVSNVKCNWNEPNLPTQLCQSCTRRLISAYEFIRDVEKSNETLQELCSHLEREQSAATVVNVDVDEYEELVQEEDHFVQLDECESVIELHEEEEEEAEVEAELVHSEETTCEEKPLLNNSNDEPSELVQEDSDAEISVEPDLLEERPSQLGMRLAHSQNYMYKCASCPRIFAKNKSLARHFATAHRQAANVAAQELAREHSSSGALICEHCPRLFKRQDTLRRHLIAFHPEVVAASGDADDVARSVPPKRAAKRRECPHCGISFPVSSLTIHIRRHTGDNPYKCDVCDKAFPRGQDLNLHKRQHTGERPSECKICAKKFISQNKLARHMRLHTGHRPYACDKCDKRFVQSNDLKIHMRRHTGERPYACGVCDKSFVCGSLLNIHRNQKRHHETGREGVDYLDPVDPYENSRVNKRRAEDIERMRLQREGESMPPMLLRPYNCGICGDNFKSGALLTIHRNKMAHYEIGKVDYGDPYEQRYKQQQHLRTAQSED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01320633;
90% Identity: iTF_00522393;
80% Identity: -