Basic Information

Insect: Drosophila neoperkinsi
Gene Symbol: -
Assembly: GCA_037043555.1
Location: JBAMBG010002444.1:36089-37796[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0001 0.0076 16.7 2.1 1 23 97 119 97 119 0.97

2 11 6.4e-07 4.7e-05 23.6 3.4 1 23 125 148 125 148 0.97

3 11 9.4e-06 0.00069 19.9 0.5 1 23 154 176 154 176 0.97

4 11 0.00014 0.01 16.2 0.5 1 23 182 204 182 205 0.95

5 11 1.6e-06 0.00012 22.4 2.0 1 23 212 234 212 234 0.97

6 11 0.0051 0.37 11.4 0.6 1 23 240 263 240 264 0.96

7 11 0.0018 0.13 12.7 0.2 1 23 269 291 269 291 0.97

8 11 2e-05 0.0014 18.9 2.7 1 23 297 319 297 319 0.98

9 11 8.5e-06 0.00062 20.1 2.6 1 23 325 347 325 347 0.99

10 11 0.0023 0.17 12.5 1.3 1 23 353 378 353 378 0.95

11 11 0.0056 0.41 11.2 0.2 1 19 384 402 384 405 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0001	0.0076	16.7	2.1	1	23	97	119	97	119	0.97
2	11	6.4e-07	4.7e-05	23.6	3.4	1	23	125	148	125	148	0.97
3	11	9.4e-06	0.00069	19.9	0.5	1	23	154	176	154	176	0.97
4	11	0.00014	0.01	16.2	0.5	1	23	182	204	182	205	0.95
5	11	1.6e-06	0.00012	22.4	2.0	1	23	212	234	212	234	0.97
6	11	0.0051	0.37	11.4	0.6	1	23	240	263	240	264	0.96
7	11	0.0018	0.13	12.7	0.2	1	23	269	291	269	291	0.97
8	11	2e-05	0.0014	18.9	2.7	1	23	297	319	297	319	0.98
9	11	8.5e-06	0.00062	20.1	2.6	1	23	325	347	325	347	0.99
10	11	0.0023	0.17	12.5	1.3	1	23	353	378	353	378	0.95
11	11	0.0056	0.41	11.2	0.2	1	19	384	402	384	405	0.95

Sequence Information

Coding Sequence: ATGGTACGCAGCCGTCGCAGCCTCTCCAAAGAGGATGTGGCCTCGGTGCTCACAGACAGTGGCATTTCGCTCTCATCGCCGCCGGCGGCACGCGAATCGTCGCCACAAGCGACAGGCGGCATCAAGCGACGCAAGCGAAGTGTCAACAGTGTACAGGATTTGTTTGCGGCTGATGGGGAGCCAGATGCCCAACCGGATTTCTCCGATGGCGACACGGATGCCGATGCGGATTACGTTCAGCCGGTCGCAAAGAGAGCACGCAAAGCGGACACAGGCAAACGCAAGCAGCACGTGTGCAGTCATTGCTCGAAGGAATTCGGTGGCAGGACAGATCTGCTGCGGCACATGCTCATCCACTCGGACCTGCGGCCGCACAAGTGCAGCGAGTGCGGCAAATGTTATCGCCAGGCCGTCAATCTGAAGAATCACATCACCACCGCCCACGAGCGCAAGAAACAGTTCGCCTGCACCGAGTGTCCCAAATCGTTTGCTCTAAAAGAGCGTCTCAAGCTGCATATGCGTCTGCATTCGGGCGAGAAGCCATATCCATGCTCGCTCTGCGAGAAACGTTTCGCCCGCGGTGGCCAGttgcaacagcacgTGGTATCGCATCACAAGACGAGCATACAGCAATTCAATTGCACACACTGCTCGGCCAGCTTCTCGACGAATGCCAATCTGCGCGTGCACATGGAACGGCACGAACAGGGCATGGAATACAGATGCTTCATATGCGAGAATGAGTTTCCAAACGAATTGGCGCTGCGTACGCACATTAATCAGGAACACCACAAACTGAGGCAATTTGATTGTCAAATATGCCAGAAGACCATCGAAACGGATGAGGATCTGGCGAGCCACCTGAAGAAGCATTCATCGGTTAAGGCGCACGTTTGCGAGGTGTGCAATTCGTATTTCACGCAAAAGTCCCAATACAACGTTCATATGCGAATGCACACGGGAGAGCGACCATATCAGTGTCGGATCTGTCAACAGACGTTTGCTCATTCCAGCGTGCTGAAGCTGCACATACGAAAGCACACCGGCGAGAAGCCGTTTCGCTGCCAGCTGTGTACGGATGAGGTGGCCTTCTCGCAGCTGGCGCATCTCAAGAATCATATGAAGAAGATACACAAACAGCAGAAGCCCTACATGTGTCCAAGCTGCCATGAGTTCTTCAAGATCAAAGTGGAGCTGCAGGCGCATGCCGTACGGAGCACCAAATGTCAGTCAACGGAGGAGCTCAACGATGGAGATCAGACAGCAGATATGCTGACGCTATCCAGCATACGCTTCAACATGGCCGTGGTGCTAAAGAAGATTAGCTCGGCACAGAAGCTGCGTCAGCTCGGCTATGAGAAGCGTTTAATTGACAATGTTATCATTGCCTCACTGAAACTCGCACAGCGTCCGTGCCATGACGATGCGACGCTGACACCTTTGGCCAGGCTCCGTCTGAATGTGGAGGAGTTTCTCAAGTGGATTGTGCCGGCGCAAACCATGCAAAAGTTTCGAGAGGAACTGCTCTCGATCGATACGATACTCGATAAGATTGCGACCAACTACATGAATCAAAAATAG
Protein Sequence: MVRSRRSLSKEDVASVLTDSGISLSSPPAARESSPQATGGIKRRKRSVNSVQDLFAADGEPDAQPDFSDGDTDADADYVQPVAKRARKADTGKRKQHVCSHCSKEFGGRTDLLRHMLIHSDLRPHKCSECGKCYRQAVNLKNHITTAHERKKQFACTECPKSFALKERLKLHMRLHSGEKPYPCSLCEKRFARGGQLQQHVVSHHKTSIQQFNCTHCSASFSTNANLRVHMERHEQGMEYRCFICENEFPNELALRTHINQEHHKLRQFDCQICQKTIETDEDLASHLKKHSSVKAHVCEVCNSYFTQKSQYNVHMRMHTGERPYQCRICQQTFAHSSVLKLHIRKHTGEKPFRCQLCTDEVAFSQLAHLKNHMKKIHKQQKPYMCPSCHEFFKIKVELQAHAVRSTKCQSTEELNDGDQTADMLTLSSIRFNMAVVLKKISSAQKLRQLGYEKRLIDNVIIASLKLAQRPCHDDATLTPLARLRLNVEEFLKWIVPAQTMQKFREELLSIDTILDKIATNYMNQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324297;
90% Identity: iTF_00574209;
80% Identity: iTF_00498290;