Basic Information

Insect: Drosophila neonasuta
Gene Symbol: -
Assembly: GCA_005889595.1
Location: MRUE01000558.1:36449-41224[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00059 0.059 14.2 0.5 1 23 137 159 137 159 0.97

2 15 9.2 9.1e+02 1.0 3.1 1 23 165 188 165 188 0.95

3 15 7.3e-05 0.0072 17.1 1.1 1 23 386 408 386 408 0.98

4 15 0.86 86 4.3 2.3 1 23 414 437 414 437 0.92

5 15 0.26 26 5.9 1.4 1 23 463 486 463 486 0.92

6 15 0.001 0.1 13.4 1.9 3 23 766 786 765 786 0.92

7 15 0.042 4.2 8.4 1.4 1 23 792 815 792 815 0.98

8 15 1.3 1.3e+02 3.7 1.1 2 23 852 873 851 874 0.90

9 15 0.0037 0.37 11.7 0.8 1 23 895 918 895 918 0.97

10 15 0.029 2.9 8.9 0.6 1 23 1106 1129 1106 1129 0.90

11 15 0.00046 0.046 14.6 4.2 1 23 1142 1164 1142 1164 0.98

12 15 0.00017 0.017 15.9 0.0 2 23 1170 1192 1169 1192 0.89

13 15 0.00057 0.057 14.3 3.3 2 23 1199 1223 1198 1223 0.90

14 15 0.082 8.1 7.5 0.1 1 23 1228 1250 1228 1250 0.96

15 15 0.0019 0.19 12.6 0.3 1 23 1256 1279 1256 1279 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00059	0.059	14.2	0.5	1	23	137	159	137	159	0.97
2	15	9.2	9.1e+02	1.0	3.1	1	23	165	188	165	188	0.95
3	15	7.3e-05	0.0072	17.1	1.1	1	23	386	408	386	408	0.98
4	15	0.86	86	4.3	2.3	1	23	414	437	414	437	0.92
5	15	0.26	26	5.9	1.4	1	23	463	486	463	486	0.92
6	15	0.001	0.1	13.4	1.9	3	23	766	786	765	786	0.92
7	15	0.042	4.2	8.4	1.4	1	23	792	815	792	815	0.98
8	15	1.3	1.3e+02	3.7	1.1	2	23	852	873	851	874	0.90
9	15	0.0037	0.37	11.7	0.8	1	23	895	918	895	918	0.97
10	15	0.029	2.9	8.9	0.6	1	23	1106	1129	1106	1129	0.90
11	15	0.00046	0.046	14.6	4.2	1	23	1142	1164	1142	1164	0.98
12	15	0.00017	0.017	15.9	0.0	2	23	1170	1192	1169	1192	0.89
13	15	0.00057	0.057	14.3	3.3	2	23	1199	1223	1198	1223	0.90
14	15	0.082	8.1	7.5	0.1	1	23	1228	1250	1228	1250	0.96
15	15	0.0019	0.19	12.6	0.3	1	23	1256	1279	1256	1279	0.96

Sequence Information

Coding Sequence: ATGGCGAGCAAGCGATTGAAAATAGATGACATGGTTGTGGATTACAAATTTGCTTGTCGCTGTTGCCTTAAATCGGAGGCGGAGTTCTTCAAGCTGGACGCTCTAACCGAGTCTAGTTTAATAGACGACAATAATGGGAACTCCACAAAAATACCTCTTATACGTTTGTTATTATTCTGCATTCGAACCGAAAATCTGCCTGAGCTGCCGCAATATATTTGTGCTGATTGCAGTAAGAGTTTGCAAATTGCCTACTTTTTCATACAAAACGCTCAAAAGGCTCATGAAATTCTCTGTCGCAAATTGTGCCCTGGCAAGATAACGAAGGCGACAACGCGATTCAATGGTCAACCACCCCTAGAGCTGCATCGCGGGGACAATGTGAAGCACTTAAAGTCTTCTGTTCGCCACGAGTGCAAAATCTGTGGCGCCATTACTAGTAATCGTCTGGAACTCAAACAACATATTAGCATGCATTCAGaGCAAACGCGCCATTCATGCAAGTTGTGCAAATTCGTGACATTTAAGCAGCGACTGCTTCCCGAGCATTACAGGAAAGCGCATGGCTTAACGGCTGCTCAAATAGATCAGCAGTTGAAAATGCGCAAATCCTTGCAGGCGGCTATGTACGCTACAAATGCGACGACATCAAGGCAAGCGAGGGAAAATGATGATGCACAAGTGAAAGTGTGTACACTGGAGGACATGGAGTTACTGATTCCCACTGTGCTGACGCCCGAAGACTTCTCGCAGCCTCAACTGGACGCTGATCAACTACGTGATATTGAACAACAGCTAGGGAACTCTTTGGATGCGAATGATTCCGCCGTCTTGCCAGTTGATGGTCCTACGGGTGGCAACTCGAATATGAGCATTGGGGCGGAGTTTCTTGTCATGCCTGATGGCTCGTTGAAGCAAGTCCATGGTGGTGCTGGGGTTGTCTTCGAGTACATCGATGACAGCAAAACCCCACAGCAAATAACGGCAAATGTCACGACAAACGCAAGTTTGCATAACTTACTGGATGACTCCAAGTCGGATGTGATATACAGTGCAAGGGATATTGAAATAAACCATCCAGTCGGAGATTCATTGCCACAAATCACTGTGAAACCAAAACTTCGACCAGGTCCAGGATCGACGAGTGTAATGAAGCACAAGTGTAATCTGTGTCCCAAAGTATTTCCCACAATTGCACGCCTTAAATCTCATCAATTAACACATAGTCATTTACCCAAGTTTTATTGTGATCAGTGCTCTTATCACTCGCTGCGCAGCTCCGATCTCATTAAGCACTATACAGAGGAGCATAAATCTTCCATTGGCGATAGTAAAATTCACGTTGAGAAATCCTTGCAGTCGCTGTCGACGGACAAAAGTCGTATCTACTCTTGCGACATGTGTTTGTTTGAGACACCAAGTAGTGCTCATTTAAGATCACACTATAGTGATAAGCACATGATACAGCCAAGTGACATCCAACTGCGTCCCAGCTGGTCAAACGACACCAAGGATAAGGGATGCAGCCCGTCGCATTTGCCTCTTGGTATCACATATCCATCAACATTCACTGAATCAGCAATTGAATCATCGGCAACAACTGAGTCGACTGGAACTACAACGGCGACAACGCTACAGGATCTACAACCTGCTCAGCCGACAACGACAGCTGTGGTTACGCCTGCTGGCGATATAAACGTGGTTGTGGATGCCACCTCATTATTCTATGATGGTGgcgcagcaacatcaacagcgacaactacaagtacaacaacatcaacagaaCCAACTGAGAATGTCTCTGCAGCATTTGAAGTATTCCCGGAGCAATCTTTATCCAAATCCATAAGGACAACACCGAGGAAAGTCGATTTAAGTGGCATTCTGCCTGCTGTCAGTGTTTCTACTACTGCTGGTGGTGGCAATATTGGTGTAGTTACCACAGCAAATCCAAACAATTCTATTTTTGGAGACATGCAAGACTTCATTGACAATACCGACGTCGCCGCCATTTGCACTATACCAGCCGACGATATGCCGGTCGTTGATGGCGACGATATTGTTattgataacaataatatGAGTTTGGATTTCGATGCCGAGAATTTGTTTGATGACTTCGAGGAAGATGTTGAAGTGGGTgaagatgaggatgaggatgaggatgatcCCGAGAATGAGGATGAGAATGAAAACAATGACGCGGCTGCCGATCAAAACTTGCTACTTAccagtgatgatgatgatgtcgatgACTTTGATGACGAGCAATCCAAGCATCTACAGAAACCGTATTGTATCTATTGCAACAAAAAGTTTACCAGCCAATACAAGTTTGAGAATCATATGTTTGTACATCGCGGACTGGCGCCATATCGATGTGAACTCTGCACCAATCTGTACAATATGAAGCGTCTGCTCATACGTCACTACAAAACTGTGCATAAGCGGATGCCGACGAGGGATATGGTTCAGGCCAAGGGCGACAAAGTAACAGTGGAACGCACAGCGATCGAGAAGCTGCACGTCGGTGTGGATAAGCCTCCGATACTGATGTGTGCCAAGTGTCCTTTTGAATGCGAAGTGGAGGGTGAGATGCGAAAACATCTCAATGCTCATCATGGCATTAACGATGGCGTCTCAGTACATGCCAACGAAGTGTTTATCATACGCaAACTACCTTTTGAGTGTCCACGCTGTATTCGCTCGTTTGCGGCAAAACGCACGTTGACTCGCCATTTGCAGCGAAGTCACTTAGTAGACACAATCATTGAGATGCAGGCGCCTCAATGGACAACCAGttcagcagcaataacaacaaccactatGACGTCTACAACCGCCTTGCCGAAGAATGCACAACACAACATAGTGATAAACAGTGACACAGGAATTGAAACGGATAATGAGGATATTGACAGTAAATCATTGACCTCAACACCAACGTCTGGATTCGCAACAATTACCACAACAGCTGACACAAATGATGCTACcgatgataaacaaaaaacaactacaGAATCTTCGCCTTTAACTTCAACCTCCCAGATAACGTCCGAATCACCGACATCACcgttaacaacaacatcaacagcactCGAAAAAACACCGACAACATCAACACTTTTTCCAACGCCCACGCCATTTGATTTTGATCTGGACTTCATAGAAAATGGTGCGCatggcaacaacgacaactttaATGTATTGCCCATCACAGGACAATTGCTAAACGGCACGGATAAACTACTTACAGCAGCATTGGAGCCGTCACCAGTTAAAGATCTTCGTTCCAGGTTACCCCAAACTccaatttttgtgtgtaaacAATGCAATCAGACATTTGACGAATTGAGTAAAATGTTGCAGCATGAATTGGAGCAACATTCCAGCGGCATTGTGTCGCCGCGTAACGTCTATCAGCATCAGTGTAAAGTCTGCAACACAACATATCGAACAGTGACGCTCTTAAATTATCACATGAAAAGGCACGCACCACGCAAGATTCCTTGTAAGCAGTGTCCCAAAGAGTTCACAACGAGTGCAGAGCTAGAGCAACACGTGGATGCCGAGCATCGGACAAACACGGCCTTGAAATGTGGCATCGATGGTTGCGAAAAGACTTTTAATTACAAGCATCATCTTAAGCGACACCAAACAGCTTCCCATACTCCTGTACAATACATATGTCCCGAGTGCGGACGCGATATGTTAACCAGTCTTCTTTTAAGAAACcacataaaaatgcataagGGAACACATTCCTACAAGTGTCCAAAGTGCGTTCGGACTTATATGCGACCCGGACCCTTTCAAAGACATGCACTGCGTGAACATAAATGGCATCTTACTGAGGAtgagttaaataaaatgtatagcGTGAATGAATCCACACCTCCGATAAAAATTCGCGAACGAAGGTCGCATGATGTTGAAAACGATACGTCTGATTAA
Protein Sequence: MASKRLKIDDMVVDYKFACRCCLKSEAEFFKLDALTESSLIDDNNGNSTKIPLIRLLLFCIRTENLPELPQYICADCSKSLQIAYFFIQNAQKAHEILCRKLCPGKITKATTRFNGQPPLELHRGDNVKHLKSSVRHECKICGAITSNRLELKQHISMHSEQTRHSCKLCKFVTFKQRLLPEHYRKAHGLTAAQIDQQLKMRKSLQAAMYATNATTSRQARENDDAQVKVCTLEDMELLIPTVLTPEDFSQPQLDADQLRDIEQQLGNSLDANDSAVLPVDGPTGGNSNMSIGAEFLVMPDGSLKQVHGGAGVVFEYIDDSKTPQQITANVTTNASLHNLLDDSKSDVIYSARDIEINHPVGDSLPQITVKPKLRPGPGSTSVMKHKCNLCPKVFPTIARLKSHQLTHSHLPKFYCDQCSYHSLRSSDLIKHYTEEHKSSIGDSKIHVEKSLQSLSTDKSRIYSCDMCLFETPSSAHLRSHYSDKHMIQPSDIQLRPSWSNDTKDKGCSPSHLPLGITYPSTFTESAIESSATTESTGTTTATTLQDLQPAQPTTTAVVTPAGDINVVVDATSLFYDGGAATSTATTTSTTTSTEPTENVSAAFEVFPEQSLSKSIRTTPRKVDLSGILPAVSVSTTAGGGNIGVVTTANPNNSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNMSLDFDAENLFDDFEEDVEVGEDEDEDEDDPENEDENENNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVTVERTAIEKLHVGVDKPPILMCAKCPFECEVEGEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQWTTSSAAITTTTMTSTTALPKNAQHNIVINSDTGIETDNEDIDSKSLTSTPTSGFATITTTADTNDATDDKQKTTTESSPLTSTSQITSESPTSPLTTTSTALEKTPTTSTLFPTPTPFDFDLDFIENGAHGNNDNFNVLPITGQLLNGTDKLLTAALEPSPVKDLRSRLPQTPIFVCKQCNQTFDELSKMLQHELEQHSSGIVSPRNVYQHQCKVCNTTYRTVTLLNYHMKRHAPRKIPCKQCPKEFTTSAELEQHVDAEHRTNTALKCGIDGCEKTFNYKHHLKRHQTASHTPVQYICPECGRDMLTSLLLRNHIKMHKGTHSYKCPKCVRTYMRPGPFQRHALREHKWHLTEDELNKMYSVNESTPPIKIRERRSHDVENDTSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00553910;
90% Identity: iTF_00553910;
80% Identity: -