Dnen004297.1
Basic Information
- Insect
- Drosophila neonasuta
- Gene Symbol
- -
- Assembly
- GCA_005889595.1
- Location
- MRUE01003862.1:247-6296[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.051 5 8.1 0.2 1 23 991 1014 991 1014 0.94 2 13 5.7 5.6e+02 1.7 0.2 1 23 1175 1197 1175 1197 0.91 3 13 0.00013 0.013 16.3 2.7 2 23 1200 1221 1200 1221 0.97 4 13 4.9e-05 0.0049 17.6 0.2 3 23 1229 1249 1227 1249 0.98 5 13 4.1e-07 4e-05 24.2 4.1 2 23 1256 1277 1255 1277 0.97 6 13 3.6 3.6e+02 2.3 0.4 5 23 1290 1308 1287 1308 0.95 7 13 0.96 95 4.1 5.4 3 23 1315 1336 1313 1336 0.93 8 13 0.1 10 7.2 0.2 2 23 1347 1367 1346 1367 0.96 9 13 3.9e-05 0.0039 17.9 0.4 1 19 1373 1391 1373 1395 0.95 10 13 1.8e-05 0.0018 19.0 1.4 1 23 1403 1425 1403 1425 0.98 11 13 7.3e-05 0.0073 17.1 7.6 1 23 1431 1453 1431 1454 0.96 12 13 0.00018 0.018 15.9 6.1 1 23 1459 1481 1459 1481 0.98 13 13 0.02 2 9.4 8.2 1 23 1487 1509 1487 1510 0.95
Sequence Information
- Coding Sequence
- atggtgGACAACAGCGTGCAGTGTCCCGCTGCAGCACAGCACCAGCATCACTTCCTGGCCACGCAGCCCGCACATTTtgcgcatcagcagcagcaacagcagtcacCTATGAAGTACACGTATGCAACCACCACGCTGCCACCGCCCCCACCACCGCTACAGCTTTTTGCACAGCAGCCGACAACGTCACAGTCGCATCAGAAGCCACCGCCCGCTTATGGCGCCGCCATCACACCACCGAGTGGGAAGCACAGCAAAACCCACACGGAGATCTTTCTGAATCctccgccaccaccaccgccacagTCCGCAACGATGCCGTCTTCATCGTCGAGCTCCTGCGCCTCCTCCAGACTGCAACATccacaacagcatcaacatcaacaccagCAATCACTTCAAATTGGGAATAGCAGTATTGTGGCTATCAACTGCTCCAGCGTCGCATCGAACCTAATGGCAACATCGTCCAGTGGACGAGGCAGCAGTCGCCAATCGACCAATTCGCCATTTGGTGCACTGCTTAATGCAGCAGCGCAAGCTGCCAGCTCATCGCCCGCCTCCTCCAGCGCTTCGGTGCTGCGTTACGCTGAATCGCCGGTTGCTCACTATTTGGAACGAGAGAATGGTGATTTTATTGTGCAGGAGACGCCCAAACACATTGTCGAATGCGTCGAGAAAGATGACGGCGAGTTTTCAGTAATTGAGAGGATATATCAGTCGCCACCCAGCGTCTTGCACAtacacgatgatgatgaagaagagGAGGATCAGAGCTGGGCAAACAGCGAGGATGACGACGTCAAGGTGGCGCATAATCATGTCGAGGATGGCGACGATGAACGTGAGGACAGTCGCAGCCGAGTTGGTGGCATtaaaacgacaacgagaaagtcacgcaaaacaaaaaccggcAACAGAATCCACAAACGTGCGTCTAAACATCAGTTGGCTGCCGAAGAGGAGGAAGAGTTCATGAGCGTCGGCAGCAGTGAGAACGAAgagctggaggaggaggatcagcagcatcaccatcaccaccaTCATCAGCAATCGCCATCTTCAGCTGCTGCGCAGGTGGCTTTATCTTCGCCTCCGCAGCTTTGCACGGCCCCATCGACTAGCAGCGGAACCTCTTCAGGGTCCTCCGGCATTGTCAATTCTACATCCAGTGGCACCGTAAAGTCCAAAAAGAATCGTGTTACTGTGCTAAGCGATGTGCCGCTCAATATGAACGAATATTTGGATCTAGTAGGCAATATTGTGGCTTCAAGTCGCATCGGTGCCTCGCGTCCATTTGTCGCTGTTGCGCCCCTCCCGCTGGTCAAGGTGGAAAAGGAGGAGCCGCTGGATGACTACGACAGTCCGCCGCCAATGAAAGTTGAGGTGGAGCCAACGATGCTGTTGCCGCAACGTTTCTCGGCACCGGCACAGCAGCGTGGTCCCAAAAACATATCAAAAACATCGGCGGAATTGGTACAGATCAAGAGCGAGACTGTGGAACAACCATCTACATCGAGTGGTGGCAGCATCTTAGAGAAACATCTGACCACCAGCTACAGTGGGCAACAATCACGCAAACACTCCGCAGTCAACGATGACGATGCACGCGTCCTTCTCGAGTTTGCCAACTCAAAACAGTTGCCCTTAGCGAGTGGCAGCAATCCCACCACATTCGTGGTGAATGCAGCAAGCTTTGCGTCGGCCGGATCTGTGTTTGCCAGCAAcacgcagcagccgcagcagaaGCCCGGTGAAGAATACATACTGCCTGATGACAACAAAGTGGAAGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTTTGCCTCCTCcactcaacagcagcagcaacaacaacatcaacagcatcacCAGCAACCGCATCATCAACACGCAGCTGCGACAGTGCAGGCAGCGCATTCGACATTGCAGCAGACACAGCCGccaaattttaatgatttcaaCTTTTTGTACCACCAAaatgcaacaccaacaacggCAGCGACTTCCTCCAGCTTTGTACCCTTTGgtctgcagcaacagcaacatcagcagccacCACATGGTTCCAGTGATGCGACCAATGCAGCAACGCTTGCCTCATCCTCCAGTAACTCATCAGCAATGGATCACGACTCGTCCATGAATGCATCGTTCCGCGTGGCCAAAACACAATCATCGCTAAATGGCTGGTatcaaccacagcagcaacaacaacaggcgcatcatcatcatcaccagcagcagcaacaacagcagcaaccacagccaaCAACATCTCAAAATGTGGAGCAGTCaagcaattttattgctgcttTGGCGGCTGTCGATTGTTGCAGTGTGGCGATGGACAGTGATGCGAGTGATGCAAAGTATTTGGATCTGGACACATGTAAGCGGGAACAGTtaagcaatagcaacagtcACTTGCCCTCTGCCTCAGCATCCACATCGACAACATCATCTTCATTTGCGGCTGCTGCCACAGAGAGCAGCCTTGTTGGTGGATTGGGTTTGAATATACGCACGGATGAGAAGATGCCTGCGAAAGGAGAAATTTCCGAACAGGAGAGCAATTGCGACATTGAGAACTCTTGGAGTCAATCGATGTATGGTGACATATCACAGCGGTACTTTAGAAGCCAATTTGCGGATGGTTACAATCAACAGCTGACCGATTGGCGTCAGGACTTTTATCCTGCGCAGGATCTCagtggccaacaacagcagcgtgaACAGAAAAGATTTGATTTCAATGCGGTGGCATCCGAGTATGCGCAGCCGGATGAGCTGGACGCTTCCTCGAGCTCGGCACGAAGTAATCATTTGCTGGATGCACAGCCCTCTACCTCGACGTCATCATCGGCTTTGCTGGCTGGTCCACCAATAGCCTCGACATCTAGAGCTGCCGCCGAGGCAGAGGCAGTTGCAGCCGCCCTGCAGCGGAAGGGTCAACGTCGCAAGATCTACAGATGTCCACACTGTGTGGCAATCTTCGAGAAGCTCAAGGAACGCAACGCCCATATGATTGGAGAGCACAACTATGTCCGGCAGAACCGTCGACTCATCTGCACTCAGGCCATGGTCAATGGTGCTATGCTGGCACAGCCCCAGGCTGAACACCAAGAGcaagcccagcagcagcaactgttgctgcagccaGGTGGCAGCGATGCTCTTCACGAAGATTCGAAGGATGGTATTGTAAAGATTAAGCAGGAGCACTGTCAGGACAAACCTGATTCAACTGACCAGCAGATGCTTGATCAATTGGAAATGCCCGATGTTAAAGATGCCGGTCTATTAGGTGTTAATAGTGAGAACGCTCGCGATGCAGACGTAAAGCCTTCCACGACCGTAACAGATCTGAAGCCGACTATGCCACCGCTGAGTATGACAACACCAGCTGCCAAATTGGCAGCTATTTATCGCATGCTTATTTCCTACAATGAGTCGAAGCTTGGGCAGGACCATCATAACCTCAGCGAGCTGGAACAAAAGGCCATGGAGAAATCCATATTTCTATGCTACGTGTGCCGCACCGACTTCCCCTCGGTGAAGCTGTACGATGCCCACTTAACTGAGCATCCCGCCGAATGCTTTACGTGTGGGAAAAAATTCTATCGTTGGAAGAATTTCTCACTGCATCTGAAGCGCCATCTGGGCTGGAAGGAATTCGGTTGCTATGTCTGCGATAAGAAATTTGTGGTGCGCAGTGCTCTTGTGGAGCATATGCGCATGCATACCGGCCAAACTCCCTTGAAGTGCAAAATATGCGGCAAAAAGTTCAAACGTTATTCCAACTTGACTCAACATCGAAAGCGTCATACCAAAATGACAGTAAGGAAAAAGGAATATGTGTGTCATTGTGGCGAGGTCTTGCCATCAAAGGCACGCTTCTTGTGGCATAAAGAAACGCACGACTTGAAACCAAAATGCTGTCCGTATTGCTGTGATCGTTTTGTGCACGCCAATTCATTGCGTCGTCACATTCGGCTAGCCCATTCAGACAAATTTGATTATGCTGAGCCCATGGAATGCCCCAtgtgcaaacaaatatttgcgaaAACGTCCATTAAGGCACACATGGCAACGCACTCAACGGATCCACAATACGATTGCGCCATCTGCAATAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCACGCCAATCGCACTGCCAAGCCGTTCAAGTGCGAGCACTGCCCCAAGGCCTTTGTACGCGAACTGGACTTTAAAAATCACATGAATGCGCACAAACAGATCAAGCCCTACACATGTGAGTATTGTGGTTGTAAGTTCATACGGAAATACAATTATATGAGGCATCGGCGAGAGCATCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAGACTTTCCATAGGCACTACTATTTGATAGAGCATCGACGAATTCACACGGGTGAGCGTCCTTTCCATTGCACCATCTGCGGTAAAAGCTCCACAACGAAGACCAATCACAATAAGCATCTGAAGATACATCATTCGCGAGATCCCTTTACCGTGGAGGTCTAA
- Protein Sequence
- MVDNSVQCPAAAQHQHHFLATQPAHFAHQQQQQQSPMKYTYATTTLPPPPPPLQLFAQQPTTSQSHQKPPPAYGAAITPPSGKHSKTHTEIFLNPPPPPPPQSATMPSSSSSSCASSRLQHPQQHQHQHQQSLQIGNSSIVAINCSSVASNLMATSSSGRGSSRQSTNSPFGALLNAAAQAASSSPASSSASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEDQSWANSEDDDVKVAHNHVEDGDDEREDSRSRVGGIKTTTRKSRKTKTGNRIHKRASKHQLAAEEEEEFMSVGSSENEELEEEDQQHHHHHHHQQSPSSAAAQVALSSPPQLCTAPSTSSGTSSGSSGIVNSTSSGTVKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGASRPFVAVAPLPLVKVEKEEPLDDYDSPPPMKVEVEPTMLLPQRFSAPAQQRGPKNISKTSAELVQIKSETVEQPSTSSGGSILEKHLTTSYSGQQSRKHSAVNDDDARVLLEFANSKQLPLASGSNPTTFVVNAASFASAGSVFASNTQQPQQKPGEEYILPDDNKVEVDEIVISSSSSFASSTQQQQQQQHQQHHQQPHHQHAAATVQAAHSTLQQTQPPNFNDFNFLYHQNATPTTAATSSSFVPFGLQQQQHQQPPHGSSDATNAATLASSSSNSSAMDHDSSMNASFRVAKTQSSLNGWYQPQQQQQQAHHHHHQQQQQQQQPQPTTSQNVEQSSNFIAALAAVDCCSVAMDSDASDAKYLDLDTCKREQLSNSNSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRSQFADGYNQQLTDWRQDFYPAQDLSGQQQQREQKRFDFNAVASEYAQPDELDASSSSARSNHLLDAQPSTSTSSSALLAGPPIASTSRAAAEAEAVAAALQRKGQRRKIYRCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQAMVNGAMLAQPQAEHQEQAQQQQLLLQPGGSDALHEDSKDGIVKIKQEHCQDKPDSTDQQMLDQLEMPDVKDAGLLGVNSENARDADVKPSTTVTDLKPTMPPLSMTTPAAKLAAIYRMLISYNESKLGQDHHNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEHCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKTFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -