Basic Information

Insect: Drosophila neonasuta
Gene Symbol: pita
Assembly: GCA_005889595.1
Location: MRUE01004569.1:9782-12139[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0008 0.079 13.8 1.5 1 23 252 274 252 274 0.96

2 10 2.9e-06 0.00028 21.5 3.2 1 23 280 302 280 302 0.93

3 10 3.9e-06 0.00039 21.1 1.1 1 23 308 330 308 330 0.99

4 10 0.0012 0.12 13.2 0.2 1 23 336 358 336 358 0.97

5 10 5.2e-05 0.0052 17.5 2.1 1 23 364 386 364 386 0.93

6 10 0.0002 0.02 15.7 0.1 1 23 392 414 392 414 0.97

7 10 0.00043 0.043 14.6 6.5 1 23 420 442 420 442 0.98

8 10 5 5e+02 1.9 4.3 1 23 450 472 450 472 0.95

9 10 0.061 6 7.9 2.2 2 23 478 499 477 499 0.95

10 10 2.4e-05 0.0024 18.6 0.5 1 23 505 528 505 528 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0008	0.079	13.8	1.5	1	23	252	274	252	274	0.96
2	10	2.9e-06	0.00028	21.5	3.2	1	23	280	302	280	302	0.93
3	10	3.9e-06	0.00039	21.1	1.1	1	23	308	330	308	330	0.99
4	10	0.0012	0.12	13.2	0.2	1	23	336	358	336	358	0.97
5	10	5.2e-05	0.0052	17.5	2.1	1	23	364	386	364	386	0.93
6	10	0.0002	0.02	15.7	0.1	1	23	392	414	392	414	0.97
7	10	0.00043	0.043	14.6	6.5	1	23	420	442	420	442	0.98
8	10	5	5e+02	1.9	4.3	1	23	450	472	450	472	0.95
9	10	0.061	6	7.9	2.2	2	23	478	499	477	499	0.95
10	10	2.4e-05	0.0024	18.6	0.5	1	23	505	528	505	528	0.95

Sequence Information

Coding Sequence: ATGCACAACGGGAATATGAGCATTATCATGTTAAcgtatttttttgaatttgaatttcaggTTAACAAAGGCGATGGCATGCCCGGTTACATTTGTTTGGATTGTCGTTTGCTCTTTGAGCACAGTTATCGCTTCAAACAGATGTGTAAGAAAGCCGAAACACTCTTGCGCCAATATCCACTTACGGGGACGTGGCCAAAGGCGCTGGATAAACCTCGAGCTCCGATGGTGGGCGCCAAGCGTGAAGCGCCAACTGAAATGCAACCGAAAAAACTGCTCAATACGATGGgcaataaagcaaacaacgTTACCATTGAAAATGTACAGATATTGAAAACTGCCACGCTTCGCGGCATTGCTCAGCGCGCCGCAGCTGGACCGCCCAAGCTACTCAACGTAGCTGCCGCCAGCTCAGCTGAACCAGCTGTTCCACCACGCGCCGCAATCAAGCGATCGTATCAGGTGAAGGTGGAGAATAGCCAGGAACTTTCCATGGACGATGTGCACAATTTGATCGCTGATATTGAAGGTCAATTGGATATGGACAAAACGGCAACATGTTCGCCAGGTAAATCGCCGATGCGACTGCTCAACAAGATTACCGAGGAGCCTGTGGAACCACGCATAGCACCGCCGCAGATAAAGCATTATGACGATGGTAATGTGGCATTGGTTACCGCTGTGCTCGATCCCAATGAgctcgatgctgctgctgatcccaCGAAGAATGCCGAGCGTGTGGCCACCAATGTGTTTCCCTGCACGCATTGTCATCGCTCGTTCCCACTGCAGCAGCTACTTGACATTCACATAGCAAATCATAAACGCGAACGCAGTTTCAAGTGCCCCGACTGCGATAAGAGCTTCTTTTCCAAATATGATTTAAAGAAACACAGCTTTCTGCACACCGGCGAACGCCCTTATAAGTGCGCCATCTGTAATTCCACCTTCAATCGGCGTGCGCTGCTCAATCGCCAtgaacgcacacacaccgaTGTGCCCAAGTACATTTGCGTCTACTGCGAGCTGCCCTTCATTTCGCGCGAAGAGATGGAGAAACATACACTAAAGCACACAAAGTATCGTCCCTTCCAGTGTGACTTCTGCCAAAAATCATTTAGTTTCAAGCAATCGCTGGAGCGTCATGAGGTTTTGCACAGCACAAATTTGCCGTTCCCATGTCAATATTGCAGTCGCGGCTTTGTAACCGCTGGCAGATTGGCCAGTCATCTAAGAGCGCATGCTGGAAGACGTTCGTATCCCTGCAAGTACTGCAGGAAATCATTCCTGTTGTCGCACCATCTGTCGCGTCATATGCGAATGCATGACCTGGCCTCGACTACCACGTTCACCTGCTGCATTTGCAAGGAGTCGCACAATTCGTTTGCTAGTTTGCTCAAGCACTCATCGATCCATGCTAAGGAGTCGTTGATGTGTGCGCTGTGCAAGTCGAAATGCAGCAGTGAACACGAATTGGAATCGCATATGATGGCGCATAGACATAGCGATCGATTTGCGTGTGAATTTTGTGACTACATTTTCATCACGTACTCTGAACTGAAGAAGCACATTGATAAGGATCATGTGTTGGACATGGTGCCGTATCAGAATGTGGCCGACAAAGAAGTGAAGGAAGAGTCGGAGCTAATTGAAGAATTGCTGGCCGAAGAGCCATCAAATGAGTCTGTTGATAATGAATCAACATCGCCACCCAAGGCAAAAGTACGTAAATTGAGTGAAGAACCAAAACCGAAAGTGAAGGAAGAAGAGCTAGCAGATCAATCGGAGCAGGCATCGACCTCGACGCAGCGAGCCAGGAAATCGGGAAGCACTAGGAGCAGTGTGGGTGCCTCCGTTTCCCCCGAAGGCAAGTCCACAACACGCAAGCCACGAGCTGTCAAGACAAACAAAGCAGTCGCCAAAACAGAGGTGATTGAGGAGCCTGCTAATAAGTTGGGCAACAAGCTAAGGATTGGCAAAGTGACAAAGAAGTAA
Protein Sequence: MHNGNMSIIMLTYFFEFEFQVNKGDGMPGYICLDCRLLFEHSYRFKQMCKKAETLLRQYPLTGTWPKALDKPRAPMVGAKREAPTEMQPKKLLNTMGNKANNVTIENVQILKTATLRGIAQRAAAGPPKLLNVAAASSAEPAVPPRAAIKRSYQVKVENSQELSMDDVHNLIADIEGQLDMDKTATCSPGKSPMRLLNKITEEPVEPRIAPPQIKHYDDGNVALVTAVLDPNELDAAADPTKNAERVATNVFPCTHCHRSFPLQQLLDIHIANHKRERSFKCPDCDKSFFSKYDLKKHSFLHTGERPYKCAICNSTFNRRALLNRHERTHTDVPKYICVYCELPFISREEMEKHTLKHTKYRPFQCDFCQKSFSFKQSLERHEVLHSTNLPFPCQYCSRGFVTAGRLASHLRAHAGRRSYPCKYCRKSFLLSHHLSRHMRMHDLASTTTFTCCICKESHNSFASLLKHSSIHAKESLMCALCKSKCSSEHELESHMMAHRHSDRFACEFCDYIFITYSELKKHIDKDHVLDMVPYQNVADKEVKEESELIEELLAEEPSNESVDNESTSPPKAKVRKLSEEPKPKVKEEELADQSEQASTSTQRARKSGSTRSSVGASVSPEGKSTTRKPRAVKTNKAVAKTEVIEEPANKLGNKLRIGKVTKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509269;
90% Identity: iTF_00562643;
80% Identity: -