Basic Information

Insect: Drosophila neonasuta
Gene Symbol: PRDM13
Assembly: GCA_005889595.1
Location: MRUE01014989.1:53-2233[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00031 0.031 15.1 1.5 2 23 219 240 218 240 0.97

2 12 0.0047 0.46 11.4 3.7 1 23 246 271 246 271 0.94

3 12 1e-05 0.001 19.8 0.5 1 23 278 303 278 303 0.97

4 12 0.0085 0.84 10.6 3.9 1 23 311 333 311 333 0.97

5 12 0.00088 0.087 13.7 0.4 3 23 342 362 340 362 0.98

6 12 0.02 2 9.4 0.1 1 23 368 390 368 390 0.98

7 12 0.0035 0.35 11.8 1.5 1 23 396 419 396 419 0.98

8 12 0.0075 0.74 10.8 3.4 1 23 425 447 425 447 0.95

9 12 0.0015 0.14 13.0 1.0 1 23 453 475 453 475 0.98

10 12 1.9e-05 0.0019 18.9 0.1 3 23 536 557 534 557 0.96

11 12 0.0032 0.32 11.9 5.7 1 23 563 585 563 585 0.98

12 12 0.00016 0.016 16.0 1.9 1 23 591 613 591 613 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00031	0.031	15.1	1.5	2	23	219	240	218	240	0.97
2	12	0.0047	0.46	11.4	3.7	1	23	246	271	246	271	0.94
3	12	1e-05	0.001	19.8	0.5	1	23	278	303	278	303	0.97
4	12	0.0085	0.84	10.6	3.9	1	23	311	333	311	333	0.97
5	12	0.00088	0.087	13.7	0.4	3	23	342	362	340	362	0.98
6	12	0.02	2	9.4	0.1	1	23	368	390	368	390	0.98
7	12	0.0035	0.35	11.8	1.5	1	23	396	419	396	419	0.98
8	12	0.0075	0.74	10.8	3.4	1	23	425	447	425	447	0.95
9	12	0.0015	0.14	13.0	1.0	1	23	453	475	453	475	0.98
10	12	1.9e-05	0.0019	18.9	0.1	3	23	536	557	534	557	0.96
11	12	0.0032	0.32	11.9	5.7	1	23	563	585	563	585	0.98
12	12	0.00016	0.016	16.0	1.9	1	23	591	613	591	613	0.98

Sequence Information

Coding Sequence: ATGACTGAGGAGAAGTTGGGCCTAGCTCAAACTCTTTGTCGTGCGTGCCTAACAAAATTGAGCCAGGATGACGCCTTCGATATCTTTATTGTGCCCGGTTTGGCCAagaaattgtgtgtgtgtacttccATGACAGTGGAACAACAAGATGGATTCCCCACAAACATTTGCACCACTTGCTATAGTCGACTCAACGACTTGCATGATTTTCAGACACAATGCCTAGACTCGGTGGAAAAGTTTCGAGAGATGTTGACTAGCACCTGCATCATAGTTCGCTCAATTccagaaaacaattttaatgtgaTGAATGCAGCTGACCAGGATGCTGAAATCCCTGCCGAGGAGGAAGTCTTTGATCCTTTGCTCAATacgaaaatagaaattgaagaCGAGCAGGATGTGTTCAAAATGATAAAAGATGTTGATAAAGAAACCGTCAAAGAGCAGAATGATTTGAATGACACTTTCAACATCGAAAACAGCGACGAAAATGAAGATGTTGATTTCGAACCAGACACCAGTGACTCCGAATACTCGTTGCCGCTGTCGCGTCtcaaaagtaaagcaaaaggCACAATGAAAGCTAGATCAAGTGATAAACCAAAGAGGAAGCGTTTGCTTCCAGTGGAGCGGGAGCGTCGTCGGTTGATTGAGTGTCACATTTGCACACAAAAGTTTATAAAGATGGCCAACTACGAGGAGCATATGAAACGGCACAGTGATCTACTGCCCCATCAGTGTCCCGTGGAGACGTGTAAGACTGGCTTTACGACCTCCAATGGACTGCGTCATCACATcgaacacacgcacacagaacTCTGCCAAATGTACACTTGCACTGCCAAAGGATGCGACAAGCAATTCCCATTGAAACGATTGCTCACCAGACACATGCGAGTGGAGCACAACATTGCCAAGCCAGACATTCATCCATGCTCGGAGTGTGATAAGCTATTTCGGTGTCCCATGGCGCTCAAGAAGCACATGTACAAACACACAGGCGAGGAGAAGCCTTTTGGCTGTGACATATGCAAGAGACGCTTTGCTGCCAGCACCGAACTGCGAGATCATTTGCTGCGCCATGCGGGGATTAagcgttttgtgtgtgcctaTTGTGGTGTGGGTAAAACTACGAAACAGGAACTGGACAATCACATCTTGACGCACACCAGGGAGAAGAACTTTAAATGCGATCAGTGTGAATATGCCACGCATATCAAACAGTCGCTGACAAAGCACATTCGGGTGGTGCATATGAAAATCAGGAAACATGCCTGTAAGCACTGCGAGAAGACCTTTGGCACTGCCTATGCGCGAAGGATGCACGAGAGATTGCACACGGGAGATAGTTGCTATGAGTGCACGATCTGCAGTCGGATGTTTCTCTTTGAGAAGAATCTGACGAACCATTTGAAGGCGCACGAGAAGCGAGAGAAAAAGGCTGCTGAGAAGGAGGAAAGAAAAAAGGAGCGAGAGAAGAAATTGGGTGCAAGAGTGGAGCGCGTGGATATAGCACTTTTGGCTGGCACTGTTGTCAATCCCATTCCTACAGTTTCAGTGCCAGCGTGGACGGAAGTGGAGAAAAGAGATGGTCAAGTAATATGCCCGGAGTGTGGCAAATCCTTCAATCGCTTGGAGGGCATGAAACTGCATTACAAGGTGGTACATCAAAAGATCAAGGATTATATTTGTCGCTTTTGCCACAGACGTTTTGGGAGACTGCATTATCTGAAGGCTCATGAGAATACGCATACTGGGGAGACGCCTCATAAGTGCGACATCTGTGGCAAGGCATTCAAGGCAGACTCGACTCTCTACACACATAAGCAGTCCCACAACAAACCTCCTAGGCCACCCAAGgcgccaaagcaacaaaaagcatCTCACACAAATAGACAACCATCTCAGCGACCTAAAACCAAACTGAATACGCAGCCTACCAAAGTTCGGGAGGAGTACGAGGATCCAGCTGCAGCACATGCGGCGGCACAAGCTCAATTGATTGCCCATCAGGAAAGTCAGAATGAGATCAAGTTAAAGACGGCTGAAGCGGTTCAGAAGATTCAAACAGCAGCTCAGGAGCAACTTCAGTTGTTGAAGCGCTTGAATGAAAAGATCTCCTATGATAGTTTACCTTTACCAAATAATTGCTTAAGCATTCCCAAGGATCGTGTATGA
Protein Sequence: MTEEKLGLAQTLCRACLTKLSQDDAFDIFIVPGLAKKLCVCTSMTVEQQDGFPTNICTTCYSRLNDLHDFQTQCLDSVEKFREMLTSTCIIVRSIPENNFNVMNAADQDAEIPAEEEVFDPLLNTKIEIEDEQDVFKMIKDVDKETVKEQNDLNDTFNIENSDENEDVDFEPDTSDSEYSLPLSRLKSKAKGTMKARSSDKPKRKRLLPVERERRRLIECHICTQKFIKMANYEEHMKRHSDLLPHQCPVETCKTGFTTSNGLRHHIEHTHTELCQMYTCTAKGCDKQFPLKRLLTRHMRVEHNIAKPDIHPCSECDKLFRCPMALKKHMYKHTGEEKPFGCDICKRRFAASTELRDHLLRHAGIKRFVCAYCGVGKTTKQELDNHILTHTREKNFKCDQCEYATHIKQSLTKHIRVVHMKIRKHACKHCEKTFGTAYARRMHERLHTGDSCYECTICSRMFLFEKNLTNHLKAHEKREKKAAEKEERKKEREKKLGARVERVDIALLAGTVVNPIPTVSVPAWTEVEKRDGQVICPECGKSFNRLEGMKLHYKVVHQKIKDYICRFCHRRFGRLHYLKAHENTHTGETPHKCDICGKAFKADSTLYTHKQSHNKPPRPPKAPKQQKASHTNRQPSQRPKTKLNTQPTKVREEYEDPAAAHAAAQAQLIAHQESQNEIKLKTAEAVQKIQTAAQEQLQLLKRLNEKISYDSLPLPNNCLSIPKDRV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509260;
90% Identity: iTF_00562631; iTF_00553864;
80% Identity: -