Dnen006946.1
Basic Information
- Insect
- Drosophila neonasuta
- Gene Symbol
- hang
- Assembly
- GCA_005889595.1
- Location
- MRUE01037045.1:1-7272[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.19 19 6.3 1.0 3 23 366 387 365 387 0.93 2 15 0.25 24 6.0 3.2 3 22 494 513 492 513 0.89 3 15 0.00042 0.041 14.7 3.1 1 22 582 603 582 605 0.90 4 15 0.048 4.8 8.2 0.1 2 21 617 636 616 637 0.93 5 15 0.00048 0.048 14.5 0.2 2 23 785 807 784 807 0.95 6 15 0.0014 0.14 13.1 0.1 1 23 815 838 815 838 0.96 7 15 1.1e-05 0.0011 19.6 0.1 2 23 924 945 923 945 0.97 8 15 0.0002 0.02 15.7 2.9 2 23 1038 1060 1037 1060 0.97 9 15 0.016 1.6 9.7 0.2 2 23 1069 1091 1068 1091 0.95 10 15 0.00067 0.066 14.1 0.4 1 23 1104 1127 1104 1127 0.97 11 15 8.7e-05 0.0086 16.8 1.1 1 23 1175 1197 1175 1197 0.99 12 15 0.0013 0.13 13.1 0.9 1 23 1205 1228 1205 1228 0.96 13 15 0.19 18 6.4 0.3 2 19 1236 1253 1235 1254 0.93 14 15 5e-05 0.005 17.6 0.4 3 23 1349 1369 1348 1369 0.98 15 15 0.0035 0.35 11.8 0.1 1 23 1404 1426 1404 1426 0.97
Sequence Information
- Coding Sequence
- AATTTCTACGTATTTTTGCAGATCACATCAACGGATCGTTTATCGCTGCACATTTGCCACGCCTGCATCAGCTACTTGAACTCGTGGCAAAGCTTCAAAAATCGCTGCCTCAGTTCACAGACGAAGCAACGCCAATGGCTGGACACGGAtcgcagcaaacagcagacgCTACTGGGCTATTTGGATTTAAATCGGGCCGAGAATGGCAACGTCTcagttgagcagcagcaacatcagcaagcTGGCGAATTGAAAAGCGATTCAGCTGCGGAGAAGGCGTCTGCAAACATTTTGGATGGCATACCATCGCTGAAGAAGCGCAAATCGTTAACAGTCTATCAACGTTTGTCCAAATTGAAGCCGAAAGTCTATTTACCGTTGGATATTGCAGTGCCGCCATTGCCACCGATACCGATACCGATGACCATATCGATACCACCGCTGCCGATAACAACGCCCGTGTTATCGTCATCAACTGTTGCAACTACTGCATCAACTGCTGGTGTTGAGGTAGCAGCAACATTGCCGttaccattgccattgccactgtCGTCGCTGCCCCTTGATTTCAGCCAGTGTAAGAATCCGTCTCAGAAATTGAGCAGCAGCCTCGCTGTGCCaacaacgtcgtcgtcgtcctcaaCGTCGCTGCCacagccgctgccgctgccatcgtcgtcgtcagttGCCAGCAATGTTGTCGCTGCGTCTGCCacaagcacaacagcaacagcggccgtcacgacggcgacgacgacgccgctgCTGATGCCGGTAACGCTGCAGAGCGCCGCCCAGCAACTGCGCTTTTTCCGGCGCTATTCCTATAATCCGCTGCCCGCCGTGCCCATCAAGGATGAGCCGCTGGACGATACGGACGATGACTATCAGATGAAGTGCATTGACGAGTCCGACGACATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCGCTAATGACCTCCGACTATGATTATACGGCGCAGCACGGCGTGACGGCGGCCGTGGCGGCGGCATCGCTGCCAGCGAGCGCCGTGGCTAATGTGGCAGCCGCCGGTGACTCGAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACACGGGCAAATGCGCGCCGGCACGAACGCAATCTGCATCCGAATCTGTTCCAGCTGTCGACCGACTCGCCGAACAATACGCCAATCACAAAGCCAACGCCAGCGCTTGCGGCCGCACTGGAAATCCAAcgtgccgctgccgcagcggcggcaacggcGGAGGCAACAAAGGCGGCAGCCGGTGGCAATATATCGACGCAAAAGTATCGCCAGGTGGTGATGAACACGTTCATCAAGTGCGAGAACGGTGGCTATGACTACGACAATCCAGAGCAGTATCAGCAGCTGTTGACGCGCGACAAAGTGGAGTTCATACAGGAGAACAATGAGTTCCTCGAGCAGTACCAGACGATGACGTGTCGCTGTTGCAACAAATACTTTAGCACGTACAAGAACTTTATGGCGCATGTGCGCAAAAAGTATCCGCTTTTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGATTCGAAGGCGTTGTTCATATCGCATCTGAAGAAACGCAACTGCATCAATTTGTATCGTGTGCTCAATGCGTTGCGCGTGAAGCAACCGAATTTTGCGCATGCCAATGCCTCAGAGAAACTGAGAGCCAAGGAGCTACTGGTGAATAAGCTCTACGTGTGCAAACTGTGTCCAAAGGGTTTTCGCACCAAGCACGAGTTTCGCACCCATGTGTATGACAAGCATGCGGATGTGCAGCGCAAGGACAACAATTCGATACAGTGCAGCTTCTGTGGCCTCGACTTTGCCGATCCCGTCGACCGGCGGCGTCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACCTGTGATGCCAAACTGGAGACGCATCAGCGTTTCCTCGACCATGTCTATCAGGATCATTTGGGCGGCGTGAGCAGCGACAATGCATCGACAGCGACACAATCCGGCTTGGATCATTCGCCCGGCAAGCGGAGTTTACTCGGCGCCCTCGGTATTGGTGTCAGTCAATCGTCGTCCAACGATGAATcccgcggcagcagcagcaccatcaacaacaacaacaatgtgaataacaacagcagtcaCAACAATAcgaatgctgctgcttcctcCTTGACTTCGACGCCAGCGAAATCCGTTTCCAATGCAGCGGGTGGCTCCAGCTCTGCTAATCGCAacagcggtggcggtggcagcagcgcTGGCGGAGATTCAGCGCCCAAATCGCAGTATTTCTCACGCATGCCGCAAGTTTGTCCGATCTGCGGACAACagtacaacaactacaacaatgtgCTGCGTCACATGGAGTCAAAGCATCCCAACAAGCTGCCCGAGACGTACAAGTGTGTGCGCTGCGGTCTGGGCTATCCACGCATCTCGTATCTGCGCGAGCACATGATCAATGTGCATGGCGTGGACAAGAATCGTCATTCCGGCGGCTTTGAGTACATCGTAAATGCGGATGCCGTCAAGTTGGCCGATGGCAGCACACCGAATGTGTATACGGGACGCTACGATTATGTGATGAAGGATTTGATGTCCATAACAAATGGTGGGACACTCGATGATGACGAGGAGGAAACCGGAAGTCTGGCCAAGAAGATACGTCTcgatgacagcagcaacaacagcagcatcaacacaAGCATTGCCAACCAGCAGAAGGAGTGCCCCATCTGCAATGCGGTGTTCAGCAACAATATTGGCCTCTCGAATCACATGCGTTCGCATTACACCGCCTCCTCGACGGCGACCAATGCAGCGTTGGCTGCCGCCAATCGCATGACACCCAAATCGCTGACGATAACAGCAACGCCACCGTTGGAAGCAACAGCCGCTGCAAGCACCACCGCATCGCCAGCAGCAGTAACTACAAGTGGAGCAGGTGCAACATCGACGCCAACCGGGGGCAAAGTGCCACCGGCGATGGTGCATCAGACGCCGCAGGAACAGGCCGTGTTTCGTCGCAGTTTAGATCAGGCGGCCGATCGTCGCTTTCGCCGGATGCGTTGTCGCATCTGTCAGCGGCGCTTCAGCTCAAAGAAATCGTATCGCTATCACATGCTGACCGATCATCAGGTGCAAAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCCGAATTCGCCTACGAGAAGGGACTGAAGGTGCATCTGTTTAAGGTGCACGGACGTGCGATCAAGGATGAGATGATTGTCAAGGAATTCGAATGCAATGTCTGCTCCACCGTTTACAGTtcggagctggagctgcagcagcacaaacGTAGCGTCCACAAGTCATCGACTTCGTCCACGAACACAACGAAATcgtcgacaacaacagccacaaccaTCACAGCGCTGAACACATCAAATTCAGCGTCGGCTGTCGATTTGGGTGCGGCAGACACATCGACGGTGCTGCCGCTGTATTGGTATCAATGCAAGTACTGTCCATCCAATTTCAATACCAACAAGAAGCTGGCAATTCACATCAATTCGCACGACGAGTTCGACTCGAATGATTATTCGTGCAAGGACTGCGGCAATGTGTACAGCGGTCGCAAGAGCCTCTGGGTTCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGTGGAGTGCACGCTGTGTCGCAAGATGTTCTTCGATCGCCAGATGCTGGACAATCACACGCCCACCTGCAATCGCAAACCCATCACGGCAACCGGCGCCCATCAGCAGgatggccaacagcagcagcacagagaacaacagcaacagcaacgcggCATCTTTAAGCACAAAACgggcgacgacgatgacgaggatgaggacgatgatcagctgctgttgctcgacGATGCTCCTGgcacgccagcaacagcagccgcagcagcaacatcagctgcaacagcagccggcgATGGCAATGCTACATCGATGGCGGGCATCAAGATACGCATACCGGAGGTGGCATGCACCATTTGTGGGGCACGCTTCACAGACCAGGAGATGTTCAGCAAGCACATACAGAAGCACGAACAGGAATTGTACGTCGACAATCCGTTGGCGGCAATGTTCGACGATGGTCCCGCCGATGCGGGACAATTTCAGGTGGAGCGTCAGAACGAGAACGGGGAATACGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGGTGAGCTTTTTGGGCTTGTGCAGCGAGGTGAAAAATCTGAGAATAAAAATCATCTTCAAAACGAAAATCCTGTTGagtaaactataa
- Protein Sequence
- NFYVFLQITSTDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLDTDRSKQQTLLGYLDLNRAENGNVSVEQQQHQQAGELKSDSAAEKASANILDGIPSLKKRKSLTVYQRLSKLKPKVYLPLDIAVPPLPPIPIPMTISIPPLPITTPVLSSSTVATTASTAGVEVAATLPLPLPLPLSSLPLDFSQCKNPSQKLSSSLAVPTTSSSSSTSLPQPLPLPSSSSVASNVVAASATSTTATAAVTTATTTPLLMPVTLQSAAQQLRFFRRYSYNPLPAVPIKDEPLDDTDDDYQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAAVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRVKQPNFAHANASEKLRAKELLVNKLYVCKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTATQSGLDHSPGKRSLLGALGIGVSQSSSNDESRGSSSTINNNNNVNNNSSHNNTNAAASSLTSTPAKSVSNAAGGSSSANRNSGGGGSSAGGDSAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEETGSLAKKIRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTATNAALAAANRMTPKSLTITATPPLEATAAASTTASPAAVTTSGAGATSTPTGGKVPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKEFECNVCSTVYSSELELQQHKRSVHKSSTSSTNTTKSSTTTATTITALNTSNSASAVDLGAADTSTVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPVECTLCRKMFFDRQMLDNHTPTCNRKPITATGAHQQDGQQQQHREQQQQQRGIFKHKTGDDDDEDEDDDQLLLLDDAPGTPATAAAAATSAATAAGDGNATSMAGIKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQVSFLGLCSEVKNLRIKIIFKTKILLSKL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -