Dneo011319.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila neocordata
Gene Symbol
-
Assembly
GCA_018903615.1
Location
JAEIGI010000001.1:10619747-10622954[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 2.3 1.9e+02 2.9 3.4 3 23 269 290 267 290 0.92
2 8 0.0012 0.1 13.2 4.8 1 23 644 666 644 666 0.97
3 8 0.00054 0.044 14.3 0.2 1 23 672 694 672 694 0.98
4 8 0.00051 0.042 14.4 0.9 1 23 700 722 700 722 0.98
5 8 4.2e-07 3.4e-05 24.1 0.2 1 23 728 750 728 750 0.99
6 8 2.8e-05 0.0023 18.4 0.3 3 23 758 778 756 778 0.98
7 8 2.6e-06 0.00021 21.6 0.6 2 23 785 806 784 806 0.97
8 8 5.3e-05 0.0044 17.5 1.2 1 23 812 835 812 835 0.97

Sequence Information

Coding Sequence
ATGACAAGTGTGTCCGTGGCAAAGCAACAACAAAGAAAAGCCACAGCGAACGTGAATGAAGAAGACANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGGAGGATTCTGAATTGGAATTGGATATGGACGAAGATGAAGATGATGAGGAAGATGATGAAGAAGAGGATCTGGTATTGCAAATTGATAGTGAAGATGAGGCCGAATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGAACAAGCCCCCATTCACGCCGTCGCCGCTCCAGTCGTCAAACGTAAACCTCGTGGCCGTCCGCCCATGCGCCGAAACTCTTCTAGCTCCACTTGCTCCACCTCCACAGTAACTTCGGATTCCACCATTTCGTCTACCTCTTCAGCAAGTGCTGTAGCTGGCCAAATTTTGGCCGATGAAAAATCACATTGCTTGATTTACAGTTGCTCGCGCTGCGCAGGACACTATGAGGATGGATTCAAACTTTCTCAACATTTTCAACGGGATCATTCTCCTCATGCTCATTCCCCCTCATTTGCAGTCAGCAAAAAAACTAAAGGCAAGAAAAAATTTGAGAAAAATGAACCGGAATTAAATCCATTGCCAGTGACTGCTCAACGAGCATGTGCCAAATTGCTTGTGCAAGGGGAATCTCTGCTCCACTTGTGCCTCTCCTGCAATTCACAGTTTGTGGAACAGAAACATCTGAGCCAGCATCTCAATGAACAACATGGCTACTTTAAGATTGTAGTTCCCAAGGAGGAGCCGGTGGAGTTGCCACCAATGGCCATGGTGACTATTCCTAGGGCTATTCAGGCAGAGCAGCAGCTTCAGCAGGAGTTGGAATTACCCATACCCGCCGCACCAGAAACACCACCACCCGAACAGGATGGGAAGGATCAGCAGCAGGTTGAAGTTGTTGGTGATAATGGCTCTAGCAATGACAAACATGATCTCGAAATATTGGATTCTACGGTGGCCAAGATAACTGAAGCCCCAAAAAGTCCCAAAGTCAATAAGATGATTATTAAACTGCCAACGGGCAAAAAACGTGGCAGGAAGCGCACCAGAAAAGAGGACGATGACGAACCGAAAGTGAAGAAAAAACAGCGAAGCCAGGAAGATCAAACAAAAGATCAAGTTGACCAGCCGGAGGCAAAACAGAACAAACGCAAACCGGCAGCTAAACCCAAGGAGCAGTTAAAAAAGTCGGACGTGGAACCGGCAAAGACTAAAGAGTTGGATAACGAAAAGCAGCCAAAAGAGGATGACACAAATAAAAAGCAGGAAATAAATGAACAGCGTGGCAAAGTCAAGAAACTGCCAAAAAAGAAGGCACAACCAATTGAATCGACTGAGAAAGAGTCGGAGAAGAAGGCACAAGCAATTGAATCGACTGAAAAAGAGTCGGAAAATCCAGTGGAGAAAGAGAAACCGGATGATAAAGTGGAGAAGCAAGAACAATTACCAAAAGAGGACACCACCACAGGGGTAGGCAAACGTAAACGCACCAGAAAGACATCTGCTGTCACACAAGTTACAAACTCGGATGAATCCAAGGAGATCAAAGAGGAGACAGAAGAGGAACCCATTGAGCAACGACGCGTGCGTAAAACTCGTCAGCCGGTGGACTATGTTGATATTAAGGATGAAGAAGACGATGAGGAAGAGGAGGACGATGAGGATGAGGTGGAACCAACTTTATCAAACAACAGTTCCGCGACAGATAGCACCGCCATAGTGAAACGTGAATCTCTTGAAGAATCGTACCGTAATGGTGGTCACACCATTCACACATGCAACTTTTGCGGCAAAACATTTCAACGTTTCTCCCGCATGCAGGATCATTTGCGTCTCCATACGGGTGAGAAGCCCTATGTTTGTGGTCAATGCGGTCGAGCCTTTCGCTTGAAAATGCGCCTGGCCGAGCATCAATTGCGCCATCGAACCGAAAAAGCATTCAAATGTGAAATATGTTCAATGCCATTGGCCACCAAACAGGATCTTTCATTGCATATGCGTCATCATAAGAACGATCGCCGCTACAAGTGTGAGAGATGCGGCAAAGGTTTCGTCCGTAGTTCAGATCTATCCATCCATGTGCGCATACATACCGGAGAGAAGCCATTTGGCTGTGATCTATGTGGCAAGGCATTTCGGGCACGCCAAAATCTTGTTGTGCATCGTCGAACCCATTTGGGTGACAAGCCCATACAGTGTGAATTGTGTGACAAGCGATTCGCTAGAAAGATCGATATGCGTGTCCATATGCGAAGACATACTGGTGAAAAACCGTACAATTGCGAGTCGTGCCAGCGTGGCTACTCATCACGGGTTAATCTTCAACGTCACCAGCAAAAGGAACATAAGTCTGGCTCCTCCTCCACCACCTCCTCTTCAAAGAAAAAGCCAGTAGATCCAGAATTCGAGCCAACAACAGTAAAAGCGACTGCCTCAGTGGATGCGACGCTTCCGATACGTCGGCCCAGACGTGAGAAACTTCAACAAAAGATAGCCGCCCAAGAAAAGCTACTAAATGAACTCAAGCGGAGCTTGAGTGCCTTGCCTGAAATAGCCGAGGAATCTGCATCATCATCACCATCACCGGCACCACAAGCAAATAAATTGGATCTTGTCCAATTGCCAGCTGATGCCGGAGCCGGCTGTGGCAACCAATCGACAATCAGTCAAGTGTCGGTAACAGTTTCTATGCAGATGGCCAATCCAAAAGCAGTTCAAGACGATGAAGATGAAGAAACCACACCCGAGAAGGAGAACGCTTTGTTGTCCAGCAGTGCGCCGGCTGTTGACAAGACAAAGACCAATCGTAAAATAACAAGCTATTTTACAGTTGTTGGCCAACAGGCAACGGAATTATAA
Protein Sequence
MTSVSVAKQQQRKATANVNEEDXXXXXXXXXXXXXXXXXXEDSELELDMDEDEDDEEDDEEEDLVLQIDSEDEAEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEQAPIHAVAAPVVKRKPRGRPPMRRNSSSSTCSTSTVTSDSTISSTSSASAVAGQILADEKSHCLIYSCSRCAGHYEDGFKLSQHFQRDHSPHAHSPSFAVSKKTKGKKKFEKNEPELNPLPVTAQRACAKLLVQGESLLHLCLSCNSQFVEQKHLSQHLNEQHGYFKIVVPKEEPVELPPMAMVTIPRAIQAEQQLQQELELPIPAAPETPPPEQDGKDQQQVEVVGDNGSSNDKHDLEILDSTVAKITEAPKSPKVNKMIIKLPTGKKRGRKRTRKEDDDEPKVKKKQRSQEDQTKDQVDQPEAKQNKRKPAAKPKEQLKKSDVEPAKTKELDNEKQPKEDDTNKKQEINEQRGKVKKLPKKKAQPIESTEKESEKKAQAIESTEKESENPVEKEKPDDKVEKQEQLPKEDTTTGVGKRKRTRKTSAVTQVTNSDESKEIKEETEEEPIEQRRVRKTRQPVDYVDIKDEEDDEEEEDDEDEVEPTLSNNSSATDSTAIVKRESLEESYRNGGHTIHTCNFCGKTFQRFSRMQDHLRLHTGEKPYVCGQCGRAFRLKMRLAEHQLRHRTEKAFKCEICSMPLATKQDLSLHMRHHKNDRRYKCERCGKGFVRSSDLSIHVRIHTGEKPFGCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKIDMRVHMRRHTGEKPYNCESCQRGYSSRVNLQRHQQKEHKSGSSSTTSSSKKKPVDPEFEPTTVKATASVDATLPIRRPRREKLQQKIAAQEKLLNELKRSLSALPEIAEESASSSPSPAPQANKLDLVQLPADAGAGCGNQSTISQVSVTVSMQMANPKAVQDDEDEETTPEKENALLSSSAPAVDKTKTNRKITSYFTVVGQQATEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00577987;
90% Identity
-
80% Identity
-