Basic Information

Insect: Drosophila neocordata
Gene Symbol: ham
Assembly: GCA_018903615.1
Location: JAEIGI010000005.1:8106900-8133246[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.015 1.3 9.8 0.0 2 21 211 230 210 233 0.87

2 9 0.0014 0.11 13.0 0.4 1 23 240 263 240 263 0.92

3 9 1.3e-07 1.1e-05 25.7 1.8 1 23 269 292 269 292 0.96

4 9 8.3e-07 6.8e-05 23.2 1.6 1 23 298 320 298 320 0.97

5 9 5.4e-05 0.0044 17.5 3.6 1 23 326 348 326 348 0.97

6 9 0.00038 0.031 14.8 1.1 2 21 356 375 355 376 0.94

7 9 4.9e-09 4e-07 30.2 1.3 1 23 823 845 823 845 0.99

8 9 4e-07 3.2e-05 24.2 0.9 1 23 851 874 851 874 0.97

9 9 4.5e-05 0.0037 17.7 6.6 1 23 880 902 880 902 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.015	1.3	9.8	0.0	2	21	211	230	210	233	0.87
2	9	0.0014	0.11	13.0	0.4	1	23	240	263	240	263	0.92
3	9	1.3e-07	1.1e-05	25.7	1.8	1	23	269	292	269	292	0.96
4	9	8.3e-07	6.8e-05	23.2	1.6	1	23	298	320	298	320	0.97
5	9	5.4e-05	0.0044	17.5	3.6	1	23	326	348	326	348	0.97
6	9	0.00038	0.031	14.8	1.1	2	21	356	375	355	376	0.94
7	9	4.9e-09	4e-07	30.2	1.3	1	23	823	845	823	845	0.99
8	9	4e-07	3.2e-05	24.2	0.9	1	23	851	874	851	874	0.97
9	9	4.5e-05	0.0037	17.7	6.6	1	23	880	902	880	902	0.98

Sequence Information

Coding Sequence: ATGGAGCAATTATTGCAGGAAATGGCACGCCTGCGCGAACCTGCCTTTCATTTGGATATTCGTGGCAATGGCGTTTTTGCCAAGGTAGATCTAAATCGTTCAACACGCTTTGGACCATTTCCCGTCACACTATGCCAACAGCCCAGCAATCCAAATTTCGCATGGAAGGTCCACGCCAGTGCCTTAAGCGGCTGGCTAGAACCCTCACCCGATGTGGTTGCCTGGTTAAAAAAAATACGCGCCGTTCAGGATGAGGAAATTGAAGAGGCTAATTTACGAAGTTTTATAATGGGTGGTTATCTGTGGTACGAAACGAATCGTTTTATAGATGCTGGCAGTGAAATTGTTATCGATGGTGGACCGAAATCCCCCTACGAAATCAATGACAATTGCATAGGAGCTGCAGCAGCAGCGGCTGCAGCCGCCGTATTGGCCGCTGCAGGAGCAGGAGGCAGTGGAGCTGGTGCCAATGCCACCATTGTCAATAGTTCATTACCCAGCGATGATCGGAGCGATCGTGATAACGGTTCCCTTAATGCCGGCGACGAATTTACCAAAGATAGAAAAAACTCATCGCTAATCAGTCAAAGTGATAGTGATTTCATAGACGACGAATACGGTTTCGATATACGCTGTGAGGTCTGTGATAAAGTCTATACGGATTTAGGACGTTTGGACGATCATCTGGTCGGTGCACATCATTTCAAACAAGGTGAATTTTCCTGTGAACTTTGCTCTCAGCGTTTCAGTCATCGTCCATTGCTGATCAAGCATGGAGCTATAGCGCATAATAATATACGAAAATATTCCTGCGAGAATTGCACCAAGGTATTTTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTACCACGTCGGAGCTCGCTGTCATCCGTGCCCGGAGTGCGGTAAAACATTTGGCACCTCATCGGGCTTAAAGCAACATCAGCATATTCATTCATCGGTAAAGCCCTTTGCCTGCGAGGTCTGCTATAAGGCGTACACCCAATTCTCAAATCTGTGTCGCCATAAGCGCATGCATGCTAACTGCCGAATGCAGATCAAGTGCTCCAAGTGCGGACAGAGCTTTAGTACGGTCACTTCGTTGTCCAAGCATAAGAAATTCTGTGATTCCACGGGCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAAGCCTACCGCCCAGTTCAACACAGCCTTCGGGCGACTCTTCCGGTGAATCGACATCAGCTGCTGCTGCAGCAGCCGTCGCTGCCATGACTACGCCGCCGAATCCTTTTCTCATGTTCCGCGCTGGACCACCCTTTTTTCCCGGCTTTCCTCCATATGGACTTTTTCCGCAAAGTCCTTTGCCGGGTGCCAATTTTCCATTGTTCTTTCCAAAGCCTCCGATGGAGATGGGTTGTGGCATGCCGCCTCTAAGTTCACCTACTGCTGCAGCGTTTCGTCAGCAATTGCAGTTTGGATTGAAAATGGAAAATCGAGAGAAGACCCAAGAGCAACTCAAGGACGATGAACGGGAATCAAAGTCAGATGTAAGGTCACTTAAATCGGAACCCATGCTGCAGGTATCCGAAGAGGAGGAGGAAGACTATAATAACGAAGAAGAGTCTAAAGGTGAGAGTAAAGAGCTCGAAAAGAAGGTAAAATCGGAAAATGCATCGGAGCAACAGGGTGAAGATGATCGGAAATCTATTGATATTGTAAGCACACCACCTCCAGCAGAATCCATCCTGGAATCAACTAAAACATCAACAGCAACGGAACTTCCTTTGGATCTTTCCCTTAGCAGCAAACGTCGGAGCACTATAGCCTCACCGTCTACCAGTATGCTTTTTAGTCGCACATCCACCCCGGATTTGGGTATTGAAGCGGATGATGAGGTTGCAGAGTCCGAGCCGCCGGCAAAACTCCACAAGTCGCACAGTTCTGGAGAGAGCTCGACATCACGACAGTCCTACAAGGGGAGTAGTCCCACGCCAAGTGCTTCGCCAGGACCCACACCGTCGCCATCACCGCCCACAAGTACGGGTGGAGAGATGAGTAGTATGTCGGATAGCGGGACCCATGCTTCTGGCCTCCCATCTGCAATGGTTAACTCGGCCATGGCCTGTCCTACGGGCATACATCCATTGTTGCTCGAGGAGATTTATAGATCGCGCTCCATGGCTAGATTTCCACCACGTCCGTTTCCTTTTTTAGGCCCAGCGGGCGGACGGCAAAACATTGAGACAAAAACATCTCAATCAGGCAACAACAACATCATTAAGTATCCGCAATTGCCGTTTCCGCCCGAACCCTATTTTGATGATGTACCAATGGACAATGGCCTAACGCCACCAACCGATGGGTTTCCTCCACACTTGAACCGTTGTGTCAAGCTCAAGGATCGTTATACATGCAAGTTTTGCGGCAAAGTTTTTCCCCGATCGGCAAATCTCACTCGTCATCTGCGCACTCATACCGGCGAGCAACCGTATTCCTGCAAATATTGTGATCGCGCGTTCAGCATCTCTTCGAATCTACAGCGCCATGTTCGCAATATTCATAACAAGGAGCGTCCCTTTCGCTGCCATCTCTGTGATCGCTGCTTTGGCCAGCAAACAAACCTCGATCGGCATTTGAAGAAACACGAAACTGATGGCGGTTCCGGAGTCCAAGCCGGTTTCGGGGATTCACGTAGCTCGGCTGAGGCGGAATCTGAATGTTATTTTGATGAAATTCGCACATTCATGAATCGTGTCTATACGCCAACAAGTTTGGGTGGCGTCGATGGGGATACCGAGGAGTATGCGGGTAGTGATGATCAGATATCGGTATCGACACGTCGATCGAGTCAGAGTCAGAGTCAGACTCAGATTCCGGCTCAGTCTCAAGCAGAGGCTCAATCTCAAGCTCCAAAGTCTTTTCGGCTCCATCCACGCATGGAACAAATTTATCGTCATGTCGGTTCTCTTAGCTGGTGCTGGTGA
Protein Sequence: MEQLLQEMARLREPAFHLDIRGNGVFAKVDLNRSTRFGPFPVTLCQQPSNPNFAWKVHASALSGWLEPSPDVVAWLKKIRAVQDEEIEEANLRSFIMGGYLWYETNRFIDAGSEIVIDGGPKSPYEINDNCIGAAAAAAAAAVLAAAGAGGSGAGANATIVNSSLPSDDRSDRDNGSLNAGDEFTKDRKNSSLISQSDSDFIDDEYGFDIRCEVCDKVYTDLGRLDDHLVGAHHFKQGEFSCELCSQRFSHRPLLIKHGAIAHNNIRKYSCENCTKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCYKAYTQFSNLCRHKRMHANCRMQIKCSKCGQSFSTVTSLSKHKKFCDSTGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPPSSTQPSGDSSGESTSAAAAAAVAAMTTPPNPFLMFRAGPPFFPGFPPYGLFPQSPLPGANFPLFFPKPPMEMGCGMPPLSSPTAAAFRQQLQFGLKMENREKTQEQLKDDERESKSDVRSLKSEPMLQVSEEEEEDYNNEEESKGESKELEKKVKSENASEQQGEDDRKSIDIVSTPPPAESILESTKTSTATELPLDLSLSSKRRSTIASPSTSMLFSRTSTPDLGIEADDEVAESEPPAKLHKSHSSGESSTSRQSYKGSSPTPSASPGPTPSPSPPTSTGGEMSSMSDSGTHASGLPSAMVNSAMACPTGIHPLLLEEIYRSRSMARFPPRPFPFLGPAGGRQNIETKTSQSGNNNIIKYPQLPFPPEPYFDDVPMDNGLTPPTDGFPPHLNRCVKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYSCKYCDRAFSISSNLQRHVRNIHNKERPFRCHLCDRCFGQQTNLDRHLKKHETDGGSGVQAGFGDSRSSAEAESECYFDEIRTFMNRVYTPTSLGGVDGDTEEYAGSDDQISVSTRRSSQSQSQTQIPAQSQAEAQSQAPKSFRLHPRMEQIYRHVGSLSWCW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600473;
90% Identity: iTF_00577940;
80% Identity: -