Dneo000823.1
Basic Information
- Insect
- Drosophila neocordata
- Gene Symbol
- su(Hw)
- Assembly
- GCA_018903615.1
- Location
- JAEIGI010000004.1:2302047-2305271[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00058 0.047 14.2 2.2 1 20 226 245 226 247 0.94 2 12 2.4e-06 0.0002 21.7 0.4 3 23 298 319 296 319 0.93 3 12 1.3 1e+02 3.7 0.1 1 23 325 347 325 347 0.88 4 12 4.7e-07 3.9e-05 24.0 2.4 1 21 354 374 354 375 0.95 5 12 5.4e-06 0.00044 20.6 1.0 2 23 387 408 386 408 0.96 6 12 9.1e-05 0.0074 16.8 5.3 1 23 419 441 419 441 0.99 7 12 7e-05 0.0057 17.1 0.9 1 23 447 469 447 469 0.97 8 12 8.1e-06 0.00066 20.1 0.7 1 23 475 497 475 497 0.98 9 12 1.8e-06 0.00014 22.2 2.2 1 23 503 525 503 525 0.97 10 12 2e-05 0.0016 18.9 0.5 1 23 529 551 529 551 0.96 11 12 3.6e-05 0.0029 18.0 0.2 1 21 559 579 559 583 0.92 12 12 6.7e-06 0.00054 20.3 0.4 3 23 603 624 601 624 0.97
Sequence Information
- Coding Sequence
- ATGAGTGCCTCCAAGGAGGGCAAAAGGGCGGATAAGGAGACTGTTGTGAAAATCGTGGCCATTGATCAAGATTCCTCGGCTAAGGAAAGCAACAAACGACCTGTCACACGTATGAAATTATTGAACGATGTGACTGGTGCCGGCACTCTAACCAGTGTTAAGACGGAAAAGCGTGGAGGTGCTCGGATCAAAATACTAAACGATGACCCCATCTCTCCGCAAAGGGCAGAAAAACGAACAAGCTGTGGTAAAAAGACAGTCAGTCCCCCTTCTGCACCTGGCTCAACTGTAAAGATTCTTAACGATAAGCGTTTCTCTTCGCCAATTTCCTCAATGGAGACGGTAAAGATAAAGGCAACTACTAGTAAAAAAAAGAAAACGGACCATTATGTCCTTGAATCAGTTAAAAATGAGAACAGCAAAGTTGCCCCGGATGTTACTGCAAAAGTAGTGGTCCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACCCAAATTACTGGTGGTCGCAATACAACAGCCAATCAGAACGGCATTAAAGAAATTGTGGAACATGTCTGCGGCAAATGTTACAAGACATTCCGTCGCGTCAAGAGTTTGAAGAAACATTTGGAATTCTGTCGATATGACAGTGGCTATCATCTACGCAAGGCGGATATGTTAAAGAATCTGGAGAAAATTGAAAAGGATGCGGTAGTCATGGAGAAGAAGGACATCTGTTTCTGTTGCAATGAGAGCTACGATACTTTCCACTTGGGCCACATCAACTGCCCTGATTGTCCGAAGTCTTTTAAGACGCAAACTAGCTACGAGCGTCACATTTTTATCACCCATTCGGAATTTAACACCTTCCCCTGTTCCATTTGCAATGCTAATTTACGCAGTGCCGCCCTACAGAAGCTGCACGAAGAGCAGCACAAGAATCGTGGAAAACCATACGCATGTAAAATTTGTGGCAAAGACTTCACAAGGTCCTATCATTTAAAACGTCATCAAAAATACTCTTCATGCTCGGCCAACGAGACCGACACTATGAGCTGCAAGGTGTGTGATCGAGTCTTCTATCGCCTAGACAACCTACGTTCCCATTTAAAGCAACATCTAGGTACACAAGTGGTAAAAAAACCAGAATACATGTGTCATGTATGTAAAAATTGCTTCTACAGTTTGTCCACGCTCAACATTCACATACGCACCCATACGGGCGAGAAACCCTTCGATTGTGATTTGTGCGATAAGAAATTCTCTGCCTTGGTAGCTCTTAAAAAACATCGACGCTATCACACTGGCGAGAAACCCTACAGCTGTACAGTGTGCAATCAATCTTTTGCCGTTAAGGAAGTCCTTAATCGTCACATGAAACGTCACACGGGCGAACGCCCGCACAAGTGCAACGAGTGCGGTAAAAGCTTCATTCAGGCCACTCAATTGCGTACTCATTCCAAGGTTCATTTGCGTCCATACGCCTGTGATTTGTGCGATGAAAAGTTTAAAACGGAGAAGCAATTGGAACGGCATGTCAAGGATCACTCACGTCAGAGGCGGGCCGCTTTCTCCTGCTCTGAATGTAAACGAAACTTCCGTAATGCTGATTTGCTCAAAGAGCATATGGACGCTGGCGATCATACACCCAAGCCTCAACGCGCAAAGCGCTCGAACACCAAAATAACTGGACGCACTGATTGCGCCATTTGTGACAAGAACTTTGATAGCACTGACACATTGCGGAAACATATACGCACTGTTCACGAGTGTGATCCAGATGATATATTTGGGGTTGATCCACCATCAGCGAAACGTAGCAAAAATGTTGGCAAATCCAACGAACTGGTAGACGATGGGGAAACTGGAGACGGATTAGCTCAAAACACTTCGGCCGGCTCACTTATTTCCAGTCAAACTGATGGCAATGGTGTGGTGGTACGTGAGTTTCTTGTGGATGAGGGTGATGGCACCGCCCAGACAATTATGCTCGAAAATGAGACTTATACCATATTGCCACTTGAAGGAGAAATTGACGGTGGTAGCGTACCAGTGGCAACGGGTAAAAAGTCCAAATCAGAATCAAAGAAAAAGCAACTTCAAGTTTCGCCTGTAGTTAAGAAGGAGCAACGCAAATCATTAGCCGCCAGTTTGGCTGAGGCCATTGCTGATAACGTAGACGAAGAGGACTTTACCGGTGAAGTACTAACCGAAGAAGATGTGAAACTTAAAGAAAATGTGGCCAAATTGATTGATATGCTGGTGGATCCACCCATTCTAAAGAAATATGGCTGGCCCAACACTTCCGAGGAGACAGTGCTCTGCAAGGTGATTGAGAATTGTGGCCACGATCTGACCAAAAGTGGGGATAACTATGCGGAAATGGAATATGGAACACGTATGCGTGAATATTGCAAATTGCTATTCACTGTCGTTATACACAATGACTCCATTAAATCCTTGCTCAATAATTTTCCCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAACCATCAATAAAAAGGAGTAG
- Protein Sequence
- MSASKEGKRADKETVVKIVAIDQDSSAKESNKRPVTRMKLLNDVTGAGTLTSVKTEKRGGARIKILNDDPISPQRAEKRTSCGKKTVSPPSAPGSTVKILNDKRFSSPISSMETVKIKATTSKKKKTDHYVLESVKNENSKVAPDVTAKVVVQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTQITGGRNTTANQNGIKEIVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCNESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNTFPCSICNANLRSAALQKLHEEQHKNRGKPYACKICGKDFTRSYHLKRHQKYSSCSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKVHLRPYACDLCDEKFKTEKQLERHVKDHSRQRRAAFSCSECKRNFRNADLLKEHMDAGDHTPKPQRAKRSNTKITGRTDCAICDKNFDSTDTLRKHIRTVHECDPDDIFGVDPPSAKRSKNVGKSNELVDDGETGDGLAQNTSAGSLISSQTDGNGVVVREFLVDEGDGTAQTIMLENETYTILPLEGEIDGGSVPVATGKKSKSESKKKQLQVSPVVKKEQRKSLAASLAEAIADNVDEEDFTGEVLTEEDVKLKENVAKLIDMLVDPPILKKYGWPNTSEETVLCKVIENCGHDLTKSGDNYAEMEYGTRMREYCKLLFTVVIHNDSIKSLLNNFPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTINKKE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00600464;
- 90% Identity
- iTF_00577932;
- 80% Identity
- -