Basic Information

Insect: Drosophila neocordata
Gene Symbol: kipf
Assembly: GCA_018903615.1
Location: JAEIGI010000026.1:839641-843070[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0011 0.093 13.3 4.1 1 21 168 188 168 191 0.95

2 18 2.6e-06 0.00021 21.6 1.7 1 23 197 219 197 219 0.99

3 18 6e-06 0.00049 20.5 1.4 1 23 225 247 225 247 0.99

4 18 8.3 6.8e+02 1.2 6.3 1 23 260 283 260 283 0.93

5 18 0.00045 0.037 14.6 1.9 1 23 356 378 356 378 0.98

6 18 0.0024 0.2 12.3 0.2 1 23 383 408 383 408 0.95

7 18 5.9e-07 4.8e-05 23.7 2.4 1 23 414 436 414 436 0.99

8 18 2e-06 0.00016 22.0 4.0 1 23 442 465 442 465 0.96

9 18 9.5e-05 0.0078 16.7 3.4 3 23 523 543 522 543 0.94

10 18 2.6e-07 2.1e-05 24.8 2.3 1 23 546 568 546 569 0.95

11 18 0.022 1.8 9.3 3.2 1 23 601 624 601 624 0.96

12 18 5.6e-07 4.6e-05 23.7 4.4 1 23 673 695 673 695 0.98

13 18 6.9e-05 0.0056 17.2 0.7 2 23 700 721 699 721 0.96

14 18 2.1e-05 0.0017 18.8 3.5 1 23 726 748 726 748 0.98

15 18 0.0015 0.13 12.9 2.0 1 23 782 805 782 805 0.95

16 18 0.00013 0.011 16.3 2.0 2 21 892 911 892 913 0.94

17 18 0.00015 0.012 16.1 2.9 1 23 919 941 919 941 0.98

18 18 0.0078 0.64 10.7 2.6 1 23 946 969 946 969 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0011	0.093	13.3	4.1	1	21	168	188	168	191	0.95
2	18	2.6e-06	0.00021	21.6	1.7	1	23	197	219	197	219	0.99
3	18	6e-06	0.00049	20.5	1.4	1	23	225	247	225	247	0.99
4	18	8.3	6.8e+02	1.2	6.3	1	23	260	283	260	283	0.93
5	18	0.00045	0.037	14.6	1.9	1	23	356	378	356	378	0.98
6	18	0.0024	0.2	12.3	0.2	1	23	383	408	383	408	0.95
7	18	5.9e-07	4.8e-05	23.7	2.4	1	23	414	436	414	436	0.99
8	18	2e-06	0.00016	22.0	4.0	1	23	442	465	442	465	0.96
9	18	9.5e-05	0.0078	16.7	3.4	3	23	523	543	522	543	0.94
10	18	2.6e-07	2.1e-05	24.8	2.3	1	23	546	568	546	569	0.95
11	18	0.022	1.8	9.3	3.2	1	23	601	624	601	624	0.96
12	18	5.6e-07	4.6e-05	23.7	4.4	1	23	673	695	673	695	0.98
13	18	6.9e-05	0.0056	17.2	0.7	2	23	700	721	699	721	0.96
14	18	2.1e-05	0.0017	18.8	3.5	1	23	726	748	726	748	0.98
15	18	0.0015	0.13	12.9	2.0	1	23	782	805	782	805	0.95
16	18	0.00013	0.011	16.3	2.0	2	21	892	911	892	913	0.94
17	18	0.00015	0.012	16.1	2.9	1	23	919	941	919	941	0.98
18	18	0.0078	0.64	10.7	2.6	1	23	946	969	946	969	0.92

Sequence Information

Coding Sequence: ATGATTATGGAAAATGTGTGTCGCGTTTGTAGGGATGGCTCGGTTACCTTAGTAGAAATATTCACCGCAGTGCAGAATGGAGATGACGAAGGCGAGGAACAAGAAAAGAATTTAGCTTATGTCCTTAGTCAGTGTGCCAACTGTCAGGTTACGCGGGATGACTTACTTCCAAAACAAATATGCTTGTCTTGTGTTCTAGCAGCTCAAAATGCATTCCGATTCAAGAAAACATGCGAGCAGAGCTATCAACACTTTTGTCAACTCCTGGAGATGGGAAAGCAAAACCAGCGCAAAGAACCACAGGAAAGCCGGCGATTCAACGATAATGATGTGCTGATGGATGGTGGGCTTCATGTCATCGATGTGAGCTGCATCAAAGTAGAGCCTTTTGTCGAGCTTCAGGAGAATATATGGCCAATTAACAACCTTACTGTGGATAATGCGTCAATAACTATTCCTTCCAGTGAAGATCAGGACAACAGAACTAACGAGGTATTCCCCCATGTCTGTCAATACTGCACTAAAGGATTTCGAGGATCCTACGAGCTCAACAATCACATTCGTTGTCGTCACACAGGAGAGCGTCCTTTTAAATGCCCCCATTGCCCAAAGGACTTTTCTGTACGAATATACTTAAGGAATCATCTTCGCATTCACACGGGAGAGCGTCCATACAAATGCCCACATTGCCCTAATGCTTTTACCCTGTCCAACACCCTGAAAGCACACATTCGAAAACATGGTGATGGCCGAAATCGTTTTTTTTCCCGAAAATTGTTTAGATGCGACTGCTGTGCAGCGTCTTTTCGGAAGCACTATAGCCTCCGCATGCACAAGCAACTAAAGCATCGCAACAATGACACAATTGCCAAAACCATTGGAAAAGTCAGTGAAAAGCGCAATCACTCATCAATCCAACGTTCCAAGGCAAACGCCAAATTACAAAGTATCGTATTTCAAGAAAGTCCTGTGGAAATTAAGAAAGAACCATTTGAAGAGGTTACGGATGTTCCCCCCGTGGCTGTCCCTGTTGAATCAAATCAACAAGTTGATGATCCTAATAAATATTACTGTGCGATTTGCGACTTGAAGTTTCAATACAGATACGCTTTTTCCAACCATATGCGCTATCATACGAAGCGACCCTTTGCATGTCCTGATCCAAATTGCTCACAGGCCTTTCAAACGGAAATCAATCTCAGACAGCACCAAATGCGTTTTCATGCCTCCGATTGGCCATTTCAGTGCAAAGAGTGTCCCAAGGGTTTCTATACTAATTACAAGTTAAAGCTACATATGCGGTCTCACACTGGAGAACGTCCTTATGAATGTCCACATTGTCCACAAAAATTTACCCAAAAGCATAACTTAAATCGCCATGTTGCTAGAAGACATTCTCAGGCCGCTCCACTAGAAACAACTTCAACGGATGGACAAACTAGTGATAACTACAATATGACCGATGTGGAACCCCGCATAGTGATTAAAACGGAATTTGTAGAGCAAAATGGACCCCATGAATTCCATGAAGAGCAAATTTTACCAGATCAAGATGACAAAAACATGTGTCACATATGCGGAAAACATTTCTCAGACACGTTCAGTCTAAATCGTCATGTTAGTGGACACACAGGCTTTCAGTGTCCGCACTGTCCAAAGTCTTACACACAAAGTAATAATTTAAGAGCTCACATCCTCGGTCACCATGACAAGGACCTTAACAAGCCAGCAAATTCTGGAAGGCAAAGATCAAAGCAGGGAACATTTGTACAGTCTAAGAAACATAAAGAAAAGATTAGTTATCGTTGTAAATGGTGTCCAATTGCTTTCCGAGAACATCATAAAATGGTGCTCCATATGCAACAGAAACACAAAAAACGTTTAGAGCAGATTTCCATCGAAGAAGAACAGCCAGAAGCGAATAGCCAAAAGGATCCGATTGAATGTGCTATTGATAACATAGAAGCGGTGCCACCGGAAAAGGAAATCTCCATACCAAACGATTCGACAAAAGTTCATAAATGTAGTGTATGTGGAAAGTCTTTCACGCGGAGATTTAGTTTTATCCAGCACATCCGTACACATAAGCCTCCCTTAAACTGTACTTTGTGCCCCAAACAGTTTAACTTTTATGCTCAGCTAAGAATTCACATGCGTCTGCACACAGGCGGAAGGTTTCAATGTGCCCACTGTTCCAACTCTTATTCCCGAAAAGATAATTTAGTAAAACATATGAGCAAACATAAAATTGAAGAGCCACATAAACAAAGTGCAGATATTAACGATATGGATCAAGTTGAAGATGAGATTGTAGATGGATCTGGTGGACAGACGAGTACCCTTTATGACTGCCTACTGTGTTCCAAATCATTTCGCTATGACTATAACCTAAGGTTGCATAAGCTCATGAAACATGGCATAAACGAGAAAGCAAATGATGTAGAAAATCTAAATATGAGCTTAAGCGAATTGGAACAAGAAACGAACTTAAAATTGCGAAATAGACCTGGAGCTGGTGCATACGAAGAGCTGGAATTCGAGGACAGTGATGTTGAAAGGCGTGACATCAATAAAAAAATGGCCATTGCAAATGCGAACCTAATAATTGGTGAACAAATGCCATTCCTACAAGATCAATTGGGTAACACAGGCGGTAGCCTGGCTAAAGGAAATGTTTGCCCGTATTGCTATAAGCGCTACGTCCGGAAAGAGAGCCTAACTATTCATATGAGATGTCACACTGGTGAACGACCGTACAAATGTTCTTATTGCGATTTAAGCTTCAGTTCAAATGGCGCTTGCAAAAGACATCTTCGAGGACATACTGGAGACCTTTTTCGTTGCGATAAGTGCCCAAAAGTATATATGACTCGATCTGAATTGCGATTTCATAAATCAAGGAAACATAATGTCTCCAGAGAGGAGCCAATAGTATTAACAAAAAATTTAATTGTACGTTTAGAACGCATTAAATTACCAGCTAATGTTAAGATAGAACCGTTAGATACTTTAGCTTAA
Protein Sequence: MIMENVCRVCRDGSVTLVEIFTAVQNGDDEGEEQEKNLAYVLSQCANCQVTRDDLLPKQICLSCVLAAQNAFRFKKTCEQSYQHFCQLLEMGKQNQRKEPQESRRFNDNDVLMDGGLHVIDVSCIKVEPFVELQENIWPINNLTVDNASITIPSSEDQDNRTNEVFPHVCQYCTKGFRGSYELNNHIRCRHTGERPFKCPHCPKDFSVRIYLRNHLRIHTGERPYKCPHCPNAFTLSNTLKAHIRKHGDGRNRFFSRKLFRCDCCAASFRKHYSLRMHKQLKHRNNDTIAKTIGKVSEKRNHSSIQRSKANAKLQSIVFQESPVEIKKEPFEEVTDVPPVAVPVESNQQVDDPNKYYCAICDLKFQYRYAFSNHMRYHTKRPFACPDPNCSQAFQTEINLRQHQMRFHASDWPFQCKECPKGFYTNYKLKLHMRSHTGERPYECPHCPQKFTQKHNLNRHVARRHSQAAPLETTSTDGQTSDNYNMTDVEPRIVIKTEFVEQNGPHEFHEEQILPDQDDKNMCHICGKHFSDTFSLNRHVSGHTGFQCPHCPKSYTQSNNLRAHILGHHDKDLNKPANSGRQRSKQGTFVQSKKHKEKISYRCKWCPIAFREHHKMVLHMQQKHKKRLEQISIEEEQPEANSQKDPIECAIDNIEAVPPEKEISIPNDSTKVHKCSVCGKSFTRRFSFIQHIRTHKPPLNCTLCPKQFNFYAQLRIHMRLHTGGRFQCAHCSNSYSRKDNLVKHMSKHKIEEPHKQSADINDMDQVEDEIVDGSGGQTSTLYDCLLCSKSFRYDYNLRLHKLMKHGINEKANDVENLNMSLSELEQETNLKLRNRPGAGAYEELEFEDSDVERRDINKKMAIANANLIIGEQMPFLQDQLGNTGGSLAKGNVCPYCYKRYVRKESLTIHMRCHTGERPYKCSYCDLSFSSNGACKRHLRGHTGDLFRCDKCPKVYMTRSELRFHKSRKHNVSREEPIVLTKNLIVRLERIKLPANVKIEPLDTLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -