Basic Information

Insect: Drosophila nebulosa
Gene Symbol: -
Assembly: GCA_018150735.1
Location: JAECWO010000003.1:21275744-21277756[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.011 0.8 10.3 0.6 3 23 246 267 244 267 0.95

2 8 0.00087 0.063 13.8 0.8 1 23 330 352 330 352 0.97

3 8 0.00027 0.02 15.4 0.6 2 23 360 382 360 382 0.96

4 8 0.037 2.7 8.7 3.1 3 23 391 412 389 412 0.95

5 8 0.06 4.3 8.0 0.5 2 23 421 442 420 442 0.97

6 8 0.073 5.3 7.7 1.9 1 23 451 473 451 474 0.95

7 8 5.7e-06 0.00041 20.6 0.4 1 23 479 501 479 501 0.98

8 8 0.00057 0.042 14.3 5.9 1 23 507 530 507 530 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.011	0.8	10.3	0.6	3	23	246	267	244	267	0.95
2	8	0.00087	0.063	13.8	0.8	1	23	330	352	330	352	0.97
3	8	0.00027	0.02	15.4	0.6	2	23	360	382	360	382	0.96
4	8	0.037	2.7	8.7	3.1	3	23	391	412	389	412	0.95
5	8	0.06	4.3	8.0	0.5	2	23	421	442	420	442	0.97
6	8	0.073	5.3	7.7	1.9	1	23	451	473	451	474	0.95
7	8	5.7e-06	0.00041	20.6	0.4	1	23	479	501	479	501	0.98
8	8	0.00057	0.042	14.3	5.9	1	23	507	530	507	530	0.97

Sequence Information

Coding Sequence: ATGAATGAAATGATATGCCGACTTTGCCTGGAAGAGGGCCAAGCTGGGCTCTGTATATATGAACTGGCTAAGTTCATAGAGGAGCATCTCAACCTCAAATTGGAAGATAACGATGAGGATCTTATAAACCAGATGTTGTGCCAAAGATGCTGGCAACAGATCAAAGATTTTCAGGACTTTTGTCTTATGGTGGGCGAGAGGCAAAGGAACTTTGAAATTAAAGTGGAACAGGATGAGGAACATTTGAGGCCAGAACCAATGGTTGTGTGGAATATGGAAGAAGAGGTGGAAGAGGAGGATTTCAAATATATGTTATGTGAGACTGAAAATGATGCCCTCAACGATGATCAAGGAACAGCAGCAACAGCAATAGCAAAAGCGGAAGAGCAGCCAGAGGAACCTCTGGAAGTGAAGTTAAAAACAAAACGAGGGAAAAGGCGTCAGGAAGAACCAAAAGAGCCTCCTCTACTACGTAGACAAACCAGACAGAGGGATCGAGAAGCAGCAGCAGCCAGACAGCAAACACCTCCGAATTTAGCATCTACTTCAGAAAATAAAGTGGTGAAGCGTTTGAGCATCAAGGAAATGGCGAAAAAGTGGCAGAAGAGCCGAGTAGCCAAAAAGCCAAAGCCTCTTCCGAATTTAGTATCAGCATCTACATCGGAAGATCGTTTGGTAAAACGCTTAAATATCAAAGAAATGGACGAGTTTATAGCCGCCAATGTTCATCTGGATTGCTGTCTCTGTGGGGCATCTGTAAGCGATTTTATTGATCTCAAGCGTCATTTTCGCTCTGCGCACCAGTGTACTGGATATGTGCAATGCTGCAACAATCGTTATAAGAAGCGAACTCTTTATGTGGATCATTTGCATTATCACAAGGACCCTCAATATTTTAGCTGCCAACCATGTCAGAAAACTTTCCTCAATCGCAATAGCCATGATATGCATATGCTCAGATTTCATTCCGAACAGCAGGAGCTAGTGCATCAGTGTGTAATTTGTGAGGCGAAATTTGCCAAGAAATATCTCTTAACAATGCATGCTAAGGTGCACAGGGGATCAGAACGTCCGGAAGAATGCGAAACATGCGGCAAAAGATTTCGCACTAAATTTGAGGTCGGCGCCCATGTGAAACGCATGCATGATTCCGATTTTACTCCAGTTATATGTGACATTTGTGGCACTCATTTTCGTTGCAAGGCCAATTTTCTTATTCACAAAAAGTCTTTGCATCCCGAGGGACCTGTCGAGGAAGTGCAATGCAAATTGTGCGGTCGCTGGCTAAGAGATGAACGAAGTATGCGCAAACACCTAGCCCGTCACGACGATCGAGATGGTGATACGAAATATCGTTGTACCCTGTGTCAGGCGGAAAAATCATCGCGTGTGGCGCTGAGCAGTCACATGAGATATCATCATTCGGATAAGAAGCACAAATGCAATCTGTGTGGCAAGGAGTTCAAGCTACCCAGAGCATTAGCGGAGCACATGGCTACCCACACTGGCGTAGATCTTTATTCGTGTCCATTTTGTCCAAGGACCTTCAAATCACATGCCAATATGCACAATCACAAAAAGAAAATGCATCCCAATGATTGGGTGCGAAAATATTCACAGCCCAGCAACAAATCCAGCGGAAATGTGAATTTGGAAGGTGCAGCTACTACTGATGCAGTGGAAGGAGCAGCTACAGCTGTCATGGAAGAAACAGCTCCATATGACTCTTGTCCTCCTCCCACAACACCGGCAAATTGA
Protein Sequence: MNEMICRLCLEEGQAGLCIYELAKFIEEHLNLKLEDNDEDLINQMLCQRCWQQIKDFQDFCLMVGERQRNFEIKVEQDEEHLRPEPMVVWNMEEEVEEEDFKYMLCETENDALNDDQGTAATAIAKAEEQPEEPLEVKLKTKRGKRRQEEPKEPPLLRRQTRQRDREAAAARQQTPPNLASTSENKVVKRLSIKEMAKKWQKSRVAKKPKPLPNLVSASTSEDRLVKRLNIKEMDEFIAANVHLDCCLCGASVSDFIDLKRHFRSAHQCTGYVQCCNNRYKKRTLYVDHLHYHKDPQYFSCQPCQKTFLNRNSHDMHMLRFHSEQQELVHQCVICEAKFAKKYLLTMHAKVHRGSERPEECETCGKRFRTKFEVGAHVKRMHDSDFTPVICDICGTHFRCKANFLIHKKSLHPEGPVEEVQCKLCGRWLRDERSMRKHLARHDDRDGDTKYRCTLCQAEKSSRVALSSHMRYHHSDKKHKCNLCGKEFKLPRALAEHMATHTGVDLYSCPFCPRTFKSHANMHNHKKKMHPNDWVRKYSQPSNKSSGNVNLEGAATTDAVEGAATAVMEETAPYDSCPPPTTPAN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00503558;
90% Identity: iTF_00604418;
80% Identity: iTF_00604418;