Dneb006321.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila nebulosa
Gene Symbol
RREB1
Assembly
GCA_018150735.1
Location
JAECWO010000003.1:6502372-6508598[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.033 2.4 8.8 0.8 1 21 235 255 235 257 0.93
2 12 0.00031 0.022 15.2 0.2 1 23 267 289 267 289 0.98
3 12 0.00056 0.04 14.4 3.1 1 21 295 315 295 316 0.95
4 12 0.67 49 4.7 6.3 2 19 461 478 461 480 0.97
5 12 0.004 0.29 11.7 0.0 1 23 654 676 654 676 0.97
6 12 4.4e-05 0.0032 17.8 2.1 1 23 686 708 686 708 0.99
7 12 0.00077 0.056 13.9 2.0 1 23 714 737 714 737 0.97
8 12 0.0027 0.2 12.2 2.0 1 23 1010 1033 1010 1033 0.95
9 12 8e-05 0.0058 17.0 0.3 2 23 1409 1430 1408 1430 0.97
10 12 0.13 9.7 6.9 6.3 1 23 1436 1459 1436 1459 0.97
11 12 0.0078 0.57 10.8 0.5 3 23 1685 1705 1683 1705 0.96
12 12 0.0012 0.09 13.3 4.8 1 23 1711 1733 1711 1733 0.99

Sequence Information

Coding Sequence
ATGCTGGCAGCAACAGCAACAACAACTACTTCGACAGAAATGGAACGTCAACGCAGAGATTCCACAACCTCAGAATCCTCATTGGAACATCTTGATCTTGGCCGCACACCAAAGAAACTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGACTTACTCTCACTCTCCGAGGATGATGAAGATGGCGAGGAGGAGTCAACAACAGTTGCAGCATCTGTAACAACAACAGTGCAACAGCAACGCCCACGCCATAAACAGCGACGCAACGGCTCTGTTGCCGCCGCTGCCAGCGCCAGCATTGTGATAGACGGCGCTGCCGATGCCAATTCGCTGCGCAAGAAATTCCGCTTGAACCGCAGCAACAGCAGCAGTCTAATGAATGGTGAACTATCCGAATCGGGATTTGTCGATGGCAGTGCACACAGTGGCTATCTGATGGGCAATAGCAATGCCTCCGCTGTTGCTGCCGCTGCCAGTGTTGCTGCTGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCGGGCTCCTCATCACCTCAAGGTCTTTGCATGTCATCGTCCAGTGCTGGCGGCGATGAGCACATGAAATATCTATGCCCCATCTGCGAGGTTGTCTCGGCCACGCCCCACGAGTTTACCAATCACATCCGATGTCATAATTATGCCAATGGCGATACCGAAAATTTCACCTGTCGCATTTGCTCCAAGGTACTATCCTCAGCCTCATCCTTGGATAGGCATGTCCTTGTCCATACGGGTGAGCGACCTTTCAATTGTCGCTACTGCCACCTGACATTCACCACAAATGGCAATATGCATCGTCATATGCAGGAGCAAGTGGAGCTCGAAGATGAGGATGATGAACAAGAAGCAGCTGGAGCCATGACCATGGAGGACACCATGCCGCTAATAAAGCAAAAACGTCGTCTCAAGACGACCATCATCAACAACAACAACAACAACAACAATAACATAATAAAAAACAATGATGATGATGATGATGAAGGAGAAGAAGCCGGCAAGCATGGAGATGACACGGATGGGGATGACAATACAGATGCGGATGATGCTGATGAGGATCGCCGGACAGAAGTGGAAGTGTCCATCACTAGCACACCCGATGTGGCCGCTCTATTGGCTGGAGCCTCGCGATCAGCATCTCCCTCACCACCCCTAATCAGTTGTCCCGTCTGCTGCATGAGCGAATTCGAATCCCTGCCCAGTTTATGCCAACACTTGGATCAGCAACATTCCGATATTTTGGCCAAGTGTCGCGAGTGCGATGTCATCTTTTCCAGCCACAAGCAATTGCAGAAGCATTGCTGTCGCGGCTCAACCGGCTTACCTCCACTCCTCAGAGCGAGTAGCTCCCCCCTGCATGGTGAGGATGAGGATGAGCGGAACGACAATGCGGAGGAGAGGCAAGCCAATCATCATCGTGACAATGGTTGCCATGGCCACGTCGACGACGAAGACGACGACGATGAAGCCGAGGTGGAAAAGGAAGCCGAGGCTGAGGCCAAACAGCGAGACGATTTCTTTCATCATCTGTATCTGAAGAGCAAAACAGAAGCCATGTCCGAGGATAACAATGAGTTAATGGCAGCCACTTCGCCACCATCCCCGATCAAGCATGAGCCGAACGACAGCAAGGATCTGGCTGACATCCAGAGCATTCTCAACATGACCAGCTCCAGTTGCACGTCGAGTTTCCTGCGGAACTTTGAGCAATCCGTGAACACGCCCTGCTCGTCCAGCCAGTACAGTTTGGATGGACGCGATCAGGAGGAGGAGGCACAGGATGCCTTCACTTCTGAGTTTCGTCGCATGAAATTGCGCGGAGAATTCCCGTGCAAGCTCTGTCCAGCGGTGTTTCCCAACTTGCGTGCCCTCAAGGGACACAATCGCGTGCATTTGGGGGCGGTGGGACCCACGGGACCCTTCCGCTGCAACATGTGCCAGTTCTCCGTGTGCGACAAGGCCGCCTTGGTGCGTCACATGCGCACCCACAACGGCGATCGTCCGTACGAGTGTGCCGTCTGCAATTACGCCTTCACCACCAAGGCCAATTGCGAGCGGCATCTGAGGAATCGTCATGGCAAAACCAGTCGCGAGGATGTCAAGCGGGCCATTGTCTACCATCCGGCCGAGGATGCCAGCTGCGGTGAGGGTGAGGGCGGCAAGCTCCGCCTGAATGAGGCCGATGAGAGTTATCGTTCGGCATCGCCGCCACCCCTCGAGGTAGCTGCCACTGCCTCCCAGCTGAAGCACATGTTGATGAGCGAACCCAGCGTCGTCCAGAGTGTGCAGCAGCCGCCACTTAAGATTCAAGTCAAGAGCCTGGATCAATTGGTGGAGAAGTCAACGCCCATAAAGGTCGCTCCATCGCCATCAACAAGTGCTATCGATCTCTCCATGGATGTGCTAGATCTCAGCAAGAAGCCATCGTCGAATGCCACGACCACATTGCCCATTCACTCGCCAGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTGCGTAATCTAATGTTCCAACAATCCTCCGGATTTCCCTTTTTTGGCTTCATGACTCCACCAGCTCCACCGCCAGCGGCGTCCTCTGGCGCAGCAGCAACAGCAGAGAAGCTGCCTCCTCCATCGGCGCAGCAGCAGCAACAAATGAGTCCGTCCAGCAATCGTCTGTCCCTGCCGCCCCTCTCTCTGCCTGGTGGCCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCCAAGCAGAAGCAACGTCGCTATCGCACCGAGCGGCCCTTCGCCTGTGAGCACTGCTCGGCGAGATTCACCTTGCGATCGAACATGGAGCGACACGTGAAGCAGCAGCATCCGCAATTCTATGCCCAGCGCCAGAGGAGTGGCCACCATGTGATGCGTGGTCGTGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATGGACCTGGACTGGTGGCACCCATTTCGGAGCAAGTGAAATATGCCATTTTGGCGCAACAATTGAAGGCTCACAAGAATACGGATTTGCTGCAGCAGGCGCTGGCCCATGGGTCCAGCAGTGTGGCGGCCTCTTCGCATCTGTTGAACTTCAATTATGCTCTGGCCAATGGCAATGGGAATGGGAATGCCAATGGTCACAGTTTGGCCATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCGCAGTGGTGTCAGCAGCACTTGACCTGGACATGGAGAAGAAGAAGAAGCTGCTGGAGGAAGAGGTCGAGGTGGTGGAGGATGAGCAGCAGTCACGCAAAGATTTGCCACAAACCATCGAGACCTTGGCCAGCAATGAGGCGGCCAAGAAGGTGGCCGAAACCATATTGGAGCAGGCCATTAAGGCGGGCAAACCCATGGCCATGCCAGTAGAACCAGTGGAACCAGTGGTCGCTCCCCATCAGCCGCCATCGTCAATGAAATCGATGATTGCTCAAGTTGAATCCGTGGCCAAGTCACTGAAGGATGTGGCCAGCTCACCGTTCAACAAAGATGAATCTCCGCTCTCCGACTTGGTGCCGGTGTCCAAGCTGGTGGACAATGCCACCAGCAATCAGTCGATGCAAAGCTTCACCAGTTACTTTCGTCCCAGCGACGTGGCCAATCACATGGAGCAGAGCGATGAGGAGGGACTCGTTGCCTCCGGCAGTGCCAGCGAGAGCAACAACTCCGGCACCGAGGATGTCACCAGCAGCAGCAGCAGTGGCCAGGAGCCCAAGAAGAAATCAGCCTACAGTCTGGCCCCCAATCGTGTCTCCTGCCCCTACTGCCAACGCATGTTCCCCTGGAGCAGCTCACTCAGGCGTCACATTCTAACCCACACCGGGCAAAAGCCCTTCAAATGCTCCCACTGCCCATTGCTCTTCACCACCAAAAGCAATTGTGATCGCCATCTGTTGAGGAAGCATGGCAATGTCGAGTCGGCCATGTCCGTGTATGTCCCCACCGAGGATGTGAGCGAGCCGATTCCGGTGCCCAAGTCGGTGGAAGAGATCGAATTGGAGGAGCAGCGACGGCGGCAAGAGGCGGAGCGTGAAAAGGCCGAATTGGAGCGCGAACGAGAACGTGAACGCGAAAGGCAATTGGAGCGAGAGCGGGAAAAGGAGCGAGAGCGTGAACGTGAACGGGAACGTGAACATGAGCGAGAATTGGAATTGGAGCGAGAGCAGCAGCTTATGCAACAATTGGCTGCCGCTGCTCAACTAAGTCAGCAAATTGCCGTGGCTGCCTCATCCTCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGCCCTTCAAGTGCCATTTGTGTGAATGTTCGTTTAGCGAGCGTTTGCAGTGCTTGGATCACATCAAACAAATGCATGCCCATGAGTTTGCCCTGCTTCTGGCCAAGGGGGCCATCGAAACGGAAGAGCCCACAGCGAATCCAACAACAGGAGCAACAGCAGCTGCTCACTCCGATGATGAGTCCATGGGCATTGGCAATGGCCGTGGTGCTAGTTCCGGTTCCGGATCGGGTAAATATCCCGATTACAGCAATCGCAAAGTCATATGCGCTTTTTGTGTTCGTCGCTTCTGGTCCACCGAGGACTTGCGCCGTCATATGCGCACGCATTCGGGTGAGAGGCCATTTCAGTGCGAGATTTGTCTGCGCAAGTTCACACTGAAGCACAGCATGTTGCGCCACATGAAGAAGCATAGTGGACGGTCTCATAATGCTGGTGAGATGCAAGGTGGATCCGATTGTTCTGATGATGAGCAAATTATGAACACAACAACAGGAGCAGCAGCAACAACAACTACACCGCCACCCACACCCACCCTGCCTAATAATAATAATAATTCTCATACAAACAACAACAATAACAACAACAACAACAATAATACGAACAACAACAACAATAATAACAAATTGGGACTACGTCTACCGAAACTGCATGAGCTACTGGACAAGGCCAACGAATGGCGGGCCAGTCGTTTGGGCGAGCACAAAGAGAATCTGGGCGAAGCGGCCACGACACCGGGAGCAACTGCATCCGCTGTGGCCGGTTCAACGGATCTCATTGGCAATCTGTTGGGCATTAGCGATCAGGGTATATTGAATAAGTTGCTCTCGTCCGCCGATGAGGCAGCCAAGTTTCTGGGAGTGGACAAGTAA
Protein Sequence
MLAATATTTTSTEMERQRRDSTTSESSLEHLDLGRTPKKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDLLSLSEDDEDGEEESTTVAASVTTTVQQQRPRHKQRRNGSVAAAASASIVIDGAADANSLRKKFRLNRSNSSSLMNGELSESGFVDGSAHSGYLMGNSNASAVAAAASVAAVXXXXXXXXXXXXXXXSGSSSPQGLCMSSSSAGGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMQEQVELEDEDDEQEAAGAMTMEDTMPLIKQKRRLKTTIINNNNNNNNNIIKNNDDDDDEGEEAGKHGDDTDGDDNTDADDADEDRRTEVEVSITSTPDVAALLAGASRSASPSPPLISCPVCCMSEFESLPSLCQHLDQQHSDILAKCRECDVIFSSHKQLQKHCCRGSTGLPPLLRASSSPLHGEDEDERNDNAEERQANHHRDNGCHGHVDDEDDDDEAEVEKEAEAEAKQRDDFFHHLYLKSKTEAMSEDNNELMAATSPPSPIKHEPNDSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCPAVFPNLRALKGHNRVHLGAVGPTGPFRCNMCQFSVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCGEGEGGKLRLNEADESYRSASPPPLEVAATASQLKHMLMSEPSVVQSVQQPPLKIQVKSLDQLVEKSTPIKVAPSPSTSAIDLSMDVLDLSKKPSSNATTTLPIHSPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLRNLMFQQSSGFPFFGFMTPPAPPPAASSGAAATAEKLPPPSAQQQQQMSPSSNRLSLPPLSLPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGPGLVAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAASSHLLNFNYALANGNGNGNANGHSLAIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAVVSAALDLDMEKKKKLLEEEVEVVEDEQQSRKDLPQTIETLASNEAAKKVAETILEQAIKAGKPMAMPVEPVEPVVAPHQPPSSMKSMIAQVESVAKSLKDVASSPFNKDESPLSDLVPVSKLVDNATSNQSMQSFTSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSGQEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAEREKAELERERERERERQLEREREKEREREREREREHERELELEREQQLMQQLAAAAQLSQQIAVAASSSXXXXXXXXXXXXXXXXXXXXXXXXXXLPFKCHLCECSFSERLQCLDHIKQMHAHEFALLLAKGAIETEEPTANPTTGATAAAHSDDESMGIGNGRGASSGSGSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNAGEMQGGSDCSDDEQIMNTTTGAAATTTTPPPTPTLPNNNNNSHTNNNNNNNNNNNTNNNNNNNKLGLRLPKLHELLDKANEWRASRLGEHKENLGEAATTPGATASAVAGSTDLIGNLLGISDQGILNKLLSSADEAAKFLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-