Basic Information

Insect: Drosophila nebulosa
Gene Symbol: -
Assembly: GCA_018150735.1
Location: JAECWO010000031.1:23650269-23655207[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 7.1e-05 0.0052 17.2 0.8 1 23 157 179 157 179 0.97

2 14 0.00014 0.01 16.3 3.5 1 23 377 399 377 399 0.98

3 14 2.3 1.7e+02 3.0 3.8 1 23 405 428 405 428 0.94

4 14 0.051 3.7 8.2 0.4 1 23 444 467 444 467 0.92

5 14 0.0011 0.081 13.4 1.9 3 23 747 767 746 767 0.92

6 14 0.045 3.3 8.4 1.4 1 23 773 796 773 796 0.98

7 14 0.35 25 5.6 0.4 2 20 836 855 836 857 0.94

8 14 0.004 0.29 11.7 0.8 1 23 876 899 876 899 0.97

9 14 0.0018 0.13 12.8 0.2 1 23 1110 1133 1110 1133 0.90

10 14 0.068 4.9 7.8 6.1 1 23 1145 1167 1145 1167 0.98

11 14 0.00024 0.018 15.5 3.7 1 23 1172 1195 1172 1195 0.97

12 14 0.0022 0.16 12.5 4.0 1 23 1206 1231 1206 1231 0.95

13 14 0.00011 0.0081 16.6 0.3 1 23 1236 1258 1236 1258 0.97

14 14 4.9e-05 0.0035 17.7 0.3 1 23 1265 1288 1265 1288 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	7.1e-05	0.0052	17.2	0.8	1	23	157	179	157	179	0.97
2	14	0.00014	0.01	16.3	3.5	1	23	377	399	377	399	0.98
3	14	2.3	1.7e+02	3.0	3.8	1	23	405	428	405	428	0.94
4	14	0.051	3.7	8.2	0.4	1	23	444	467	444	467	0.92
5	14	0.0011	0.081	13.4	1.9	3	23	747	767	746	767	0.92
6	14	0.045	3.3	8.4	1.4	1	23	773	796	773	796	0.98
7	14	0.35	25	5.6	0.4	2	20	836	855	836	857	0.94
8	14	0.004	0.29	11.7	0.8	1	23	876	899	876	899	0.97
9	14	0.0018	0.13	12.8	0.2	1	23	1110	1133	1110	1133	0.90
10	14	0.068	4.9	7.8	6.1	1	23	1145	1167	1145	1167	0.98
11	14	0.00024	0.018	15.5	3.7	1	23	1172	1195	1172	1195	0.97
12	14	0.0022	0.16	12.5	4.0	1	23	1206	1231	1206	1231	0.95
13	14	0.00011	0.0081	16.6	0.3	1	23	1236	1258	1236	1258	0.97
14	14	4.9e-05	0.0035	17.7	0.3	1	23	1265	1288	1265	1288	0.97

Sequence Information

Coding Sequence: ATGCCAATGCCAGGTCAAATAGATAGAAAGAACAACGAAACGTCGAAAGCGGAGCACCAGTTCATCAAGTCCAATGTGAATTACGAATACGTTTGTCGCTGCTGTCTCAAATCGGACGCGGAATTTGTTCGACTGGATACGCTGATGGTGACGAGGAATTTAGAAGGAAATGATGAGTCGGATAAGATTCCCTTACTAAGGTGCCTGCTTTTTTGCATACGCTCAGAAAATACCCCCGACTTGCCTCAATTAATCTGCACTGAATGTAGCAAGAGTTTGCAGATCACTTACTATTTCCTCCAAAATGCTTTTCGTGCCCATGAGATCCTTTGTCGTAAACTGTGCACAGATAAGCCTTCACATTCACGTTTTGGAGAGCTGCTGAATGGCAATCTTCGACATGAGACGGCGCCACCAATAGTCGCTCAAGACAGCAAGTCGAGATCGCATAAGTCAGGCCCCGTTCGCCATGAATGCAAAATATGCGGCACCGTGGTATACAATCGTATGGAACTTAAGCAGCATATACGCCTGCACAGAGATACAATCGTTCAGAATTGCTCGATGTGCATTTTTAGCACTGTTAAGCAGCGCCATTTGGTACAACATTATGTGGATGCTCACAATCTGACAACGGCGCAGGCGGAGGAGCGCATCAACTTGGATAATATCATTACAGAGCACAGTGACAACATGAAACTCCAAGAGGGCGCCAAAGTGTGTACTTTGGAAGATATTGAAATGCTGATACCCACTGTGCTGACACCAGAGGACTATGCTCAGCCAAAAAGTGAATACAATATTGGACAGCAATTGGGCACGAGTAAAGAATTTAGTGGGAACAATGTAAGCATTGGCACTGAATTTCTTGTAATGCCTGATGGATCACTTCAACAAATAAATGGCAGTGGAGTCCTTTTTGAATACATCGATGATAGCAAGAGTAATGTTGCTCCCACGAGCAATTTAAATTTACAAAGTCTTCTGGGCAGCGACAACATTTCCATCGATCCCATGGATATAGATATTAACGAGCTTATTGTGGAAGATACCCTTCCGCAAATAAAAGTCAAGCCAAGGTCAGCAAATATTGGGTCATCTGCATCTGGCTGTCCTGCTACCTTTAAGCATAAGTGCAAACTTTGTACGAAATCTTTTGCCACTTTGGCGCGCTTAAAATCTCATCAATTAACGCACTCTAATCTACCCAAATTTCATTGCGATCAGTGTAACTTCTTTACGCTGCGTAGTTCTGATCTCGCCTCTCACCATAGGGATGTGCATATGAAACTGGATGGGGAGGTTCCTGCTGTAGAAGAGTCGCGGACCTTTTCATGTGACTTATGCTTGTTTGAGACCAGGAATCCAAGCCAGCTGCGCGAACATTACACTGGAGATCACATGATTCGGCCTTCGGAGGTGCAGTTGCGTCCGAATTGGACTGCTGAGATGGAACCGATGGTGACCACGGCAGCTCTTACCTCTGAACTGACCCAAGATCATAGACAAGACACCGATATTCCATATCCGGTGGCTGTACAACCAATGCTTCCAGATATTGCCAAAGATATTATTATGCAGCCGCCGCAGGCGAAAACAACAGCAACAGTAACTCCAATGGGCGATATTAGTGTGGTTGTTGATGCCACACCATTGTTTTTCCCAAATGGCCCACAAACAGCTGTAACTACTTCCGCAACACAAGCTTCCCCAATTCCACCTATAGTTGAAAGCAACTGCAACAAGAACAACAACAACACATTTTCAGCATTTCCAGAAATCTCGGCCAGCGACAGCCTTGTGGCAACATCTGAGTCAACAATTCCACCGATACCAAACCAAAATTTGCCATCGACATCAGCAAACTCATTGATATTTGGGGATATGCAAGATTTTATCGATAATACAGACGTGGCTGCCATATGCACCATACCGGCGGATGGAATGCCCGTTGTCGATGGCGATGATATTGTCATTGATAACAATAATATAAGTTTAGACTTTGATGCGGAAAATCTCTTCGGGGAATTCGAAGAGGAAGATGAGGACGCAGTGGTTAACGAGAACGACGATGCGGAAGAGGAGGCGGGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAGTCGAAACATCTGCAGAAACCATATTGTATATACTGCAACAAAAAGTTTACCAGCCAATACAAATTCGAGAATCATATGTTTGTCCATAGGGGTCTGGCTCCCTATCGTTGTGAATTGTGTACGAATCTCTACAATATGAAACGTCTACTCATCCGGCATTACAAGACCGTACATAAAAAGATGCCCACTCGCGATATGGTCCAAGCAAAGGGCGACAAGATTTCAGTGGCTCGTTCAAATAAGGAGATAATTCATGTCGATGTGGTTAGAAATCCAATGCTTATGTGCGCCAAGTGTCCATTTGAATGTGGGATGGATACGGAGATGAAAAAGCATTTAAATGCTCACCATGGTATAAATGATGGTGTTTCCGTACACGCAAATGAGGTATTCATTATACGCAAATTACCATTTGAGTGTCCCCGTTGTATTCGTTCGTTTGCTGCAAAACGAACATTAACACGTCATTTACAACGTAGTCATCTGGTGGACACCATAATTGAGGTAACAAATCCAGCACCCACAACAACAACAACAGTGGCCGAAACAGTGTCAGCGAGCAATGCCGAAGACACTGGAAATAAGCTAGCTGCTGCTGCTGCTCCATCGCTGGCTGCTGAAGAAATTGGTGTCGGCGAATGCGAAATCGAAATGCCCGAAAAAAATGGGACAGCTGAAAGTGAAGCCGCGGCAGTTGTTGATAATGAGAATGCGACAGCTACATCTAGTACGTCTTCCACTTCTACAGCAAAAACAACAACAACTACTGCGGGGCATGCAGCTTCACCAACAGTGACCACAGCTTCATCATCTTCTACAATTTATACTACACCCACACACTTTGATTTCGACTACGATTTTATCGGTGAAACCACCTCCACGCCCAATGGCAGCACCAACAACCCAAACACAAACACCACAAGCAACACCACCACAAATACCACCACTACCAATACCAATAACAACAACAATAGTACCGCAGATGGTTACACAGGTGCAGACACAGTGCTTCCCAGTCATGTTCTCAATGGCAGCGACAAACTATTAACTGCAGTCACAATGGAGCCATCCCCCATTAAGGATGGAAGAACAAGGCTTCCACGCACCCCAATTTATGTGTGCAAATTGTGCAATAAGACATTCGATGAACTGGGTAAACTTGTGAAGCATGAAGCGGAGCTGCATTCGGGCAAGGAACCGCGTCGCACTGTCTTTCAGCACAAGTGTTCTACTTGTAACTCAACATTTCGTACCCTGACATTGCTTAAGTTTCACATGAAGAGGCACTTAATTCGCAGATTTCAGTGCAATCGATGTTCAAAGTGTTTTATCAAAAAGACGGAATTAGACCGACACATATTAATTAAGCACGCGGAAAAGCATGACAGTAAAGAGAAAGCCTTCAGATGCTCATTGGATGGGTGTACCAAGACGTTTAATTATAAACATCACATGGTTCGTCATCAAAATGCAGTGCATCTGAAGGTCCGTCATATATGCAATGTTTGTGGTCAGGATTTGGGATCAAGTTTTAACCTACGAGCTCATATGCGCGTCCACAGTGGCAATGGACAGTCGTACAAGTGTCCCAATTGTGAAAAAACATACGTGCGACGCGGACCCCTTCGCCAACATGCTCGACAGGCCCATCAAGTTGAGCTAACTGACAGTGACTGGGCAAGAATGTTATGCAATAATGTTCGCTCCAACAATTTGCATATAAAAAAGGCTTTCTCGCGTAAAAAGGAATCCTCAGCAAAAATACAAAAAGACAATTAA
Protein Sequence: MPMPGQIDRKNNETSKAEHQFIKSNVNYEYVCRCCLKSDAEFVRLDTLMVTRNLEGNDESDKIPLLRCLLFCIRSENTPDLPQLICTECSKSLQITYYFLQNAFRAHEILCRKLCTDKPSHSRFGELLNGNLRHETAPPIVAQDSKSRSHKSGPVRHECKICGTVVYNRMELKQHIRLHRDTIVQNCSMCIFSTVKQRHLVQHYVDAHNLTTAQAEERINLDNIITEHSDNMKLQEGAKVCTLEDIEMLIPTVLTPEDYAQPKSEYNIGQQLGTSKEFSGNNVSIGTEFLVMPDGSLQQINGSGVLFEYIDDSKSNVAPTSNLNLQSLLGSDNISIDPMDIDINELIVEDTLPQIKVKPRSANIGSSASGCPATFKHKCKLCTKSFATLARLKSHQLTHSNLPKFHCDQCNFFTLRSSDLASHHRDVHMKLDGEVPAVEESRTFSCDLCLFETRNPSQLREHYTGDHMIRPSEVQLRPNWTAEMEPMVTTAALTSELTQDHRQDTDIPYPVAVQPMLPDIAKDIIMQPPQAKTTATVTPMGDISVVVDATPLFFPNGPQTAVTTSATQASPIPPIVESNCNKNNNNTFSAFPEISASDSLVATSESTIPPIPNQNLPSTSANSLIFGDMQDFIDNTDVAAICTIPADGMPVVDGDDIVIDNNNISLDFDAENLFGEFEEEDEDAVVNENDDAEEEAGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKKMPTRDMVQAKGDKISVARSNKEIIHVDVVRNPMLMCAKCPFECGMDTEMKKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKRTLTRHLQRSHLVDTIIEVTNPAPTTTTTVAETVSASNAEDTGNKLAAAAAPSLAAEEIGVGECEIEMPEKNGTAESEAAAVVDNENATATSSTSSTSTAKTTTTTAGHAASPTVTTASSSSTIYTTPTHFDFDYDFIGETTSTPNGSTNNPNTNTTSNTTTNTTTTNTNNNNNSTADGYTGADTVLPSHVLNGSDKLLTAVTMEPSPIKDGRTRLPRTPIYVCKLCNKTFDELGKLVKHEAELHSGKEPRRTVFQHKCSTCNSTFRTLTLLKFHMKRHLIRRFQCNRCSKCFIKKTELDRHILIKHAEKHDSKEKAFRCSLDGCTKTFNYKHHMVRHQNAVHLKVRHICNVCGQDLGSSFNLRAHMRVHSGNGQSYKCPNCEKTYVRRGPLRQHARQAHQVELTDSDWARMLCNNVRSNNLHIKKAFSRKKESSAKIQKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00604298;
90% Identity: iTF_00604298;
80% Identity: -