Basic Information

Insect: Drosophila nebulosa
Gene Symbol: -
Assembly: GCA_018150735.1
Location: JAECWO010000003.1:6195907-6198070[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.11 8 7.1 0.5 3 23 314 335 313 335 0.92

2 10 0.0002 0.015 15.8 0.5 6 23 344 361 344 361 0.99

3 10 9.1e-06 0.00066 20.0 0.3 1 23 367 390 367 390 0.98

4 10 2.5e-05 0.0018 18.6 0.7 1 23 402 424 402 424 0.97

5 10 5.4e-05 0.0039 17.6 3.0 1 23 431 454 431 454 0.96

6 10 1.3e-05 0.00092 19.5 1.8 1 23 460 482 460 482 0.96

7 10 0.16 11 6.7 1.0 2 23 491 512 490 512 0.96

8 10 6.1e-05 0.0045 17.4 2.9 3 23 519 540 517 540 0.95

9 10 1.9e-07 1.4e-05 25.3 0.7 2 23 547 568 546 568 0.97

10 10 0.00019 0.014 15.8 4.4 1 23 574 597 574 597 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.11	8	7.1	0.5	3	23	314	335	313	335	0.92
2	10	0.0002	0.015	15.8	0.5	6	23	344	361	344	361	0.99
3	10	9.1e-06	0.00066	20.0	0.3	1	23	367	390	367	390	0.98
4	10	2.5e-05	0.0018	18.6	0.7	1	23	402	424	402	424	0.97
5	10	5.4e-05	0.0039	17.6	3.0	1	23	431	454	431	454	0.96
6	10	1.3e-05	0.00092	19.5	1.8	1	23	460	482	460	482	0.96
7	10	0.16	11	6.7	1.0	2	23	491	512	490	512	0.96
8	10	6.1e-05	0.0045	17.4	2.9	3	23	519	540	517	540	0.95
9	10	1.9e-07	1.4e-05	25.3	0.7	2	23	547	568	546	568	0.97
10	10	0.00019	0.014	15.8	4.4	1	23	574	597	574	597	0.96

Sequence Information

Coding Sequence: ATGATATGTCGTTTGTGCTTGCGGAGCATAAATGCCAACACTGCCGTTTTCTTATTTGAGACCAACGAAACACTGGCCGAAACTAGGCTGGTCAAGATGATAGCTAAATTTCTTCAGCTGGAGATTATGCCGGATGACAGCGTCTCAACTAGCGTTTGTACTGTATGCTGCGAGCATTTGGAGGACTTCAATAGTTTTTGGCAGCTTGTGGAACAAAAGCAGGGAACCTTAAAAAAGGAATTTCTTACTGTGGATGTAGACTGTGGGATCATGAAATGGTCGTCAGGCGTTGGCGAAATGGATGTGGTGGATGTTAATGCTGATGAATTACCTGTGGTAAGTGTAAATATGGATGAAGATGAGAAGCCGCTGCCACTGGATATGCACAACCTAAGTCTGCTGGGCAGTGTTTTGGATGTAAATGTCGATGGGCAGGACGAGGAGCTGGAGGAAGAGATGCCACCAGTGTTAATAAAAAAACAAAAGCCTGACTATAATTCTGATGATAACGAAAACGAGGAAGAGGATGAGGATGAAGATGATGAAGATGAGAAGCCCATGCTTGAGGCTAGCGAAAGTGAATTTGGTGAAGCAGATATAGCAGATGCAGAACCACTAGGAGATGATTCCTCCGATGATGAGCCTCTGGTAAAACTGGTTATGCAGTCCAACAATCAAAAACCCAAACGAAAATATACCAAGAACAAGCGACATTTAAGTCTTGCCATGGAATTGAAAGATTTGCTTGATGAAGATTGCTCCAGCAAATTATTGTCCCACCGTCGCCGCAAGGGAGCCCAACAAAGTCGTCGGGACAGCCCAACTGAGACACAGGAGACCGAACTGCAAGCGGCATTGGAACGCAAACCGAAAGGCTGCTCTAGGGCACAGCTGACCAAACGATATGAGGAGGTCATTGCTAGTTATATGAGTGCCAATTGTGATCTCTGCGATTTCAGTGGCAAATTCCTATCCGAATTAAAAACGCATTTCCAGGAGGTGCATCAACGGGAGTTTTATATAAAATGCTGCAATAAGATATTCACAAGAGCCTCTAAGCTGATGGATCACATACGAAAGCATGTCAATCCTAAACTATTTACCTGTTCGATTTGCAACAAATCACTCAATTCGCAGGATTATCTGGCCACACACATTGAGACCGTGCACAATAAAGTGGATCAAATTGGCAAAGTTTTAAAATTCCCCTGTCCCAAATGTGAGCGCACCTTTAGCAGCGAGCGCCGTTTGACCAATCATTTGGCCAAACATGATACGGATCAATTGGAGCACAGTTGCGACATATGCCAAAAGAGCTTCGCCAATGTCCATCGCCTACGCCGTCACATTCAATCCATACACGAAGATCTGCATCCACACGTTTGTGATATATGTGGCAAGAAATTTAAATTCAAACCATCATTCGAGCGCCATCTGCTCGAGCATCAGGGTGTTGTTGCACCTGCCATGGAGTGCACCATTTGTGGGGTTTGGCTGAAAAATGAGCATAGTTTGCGTCTACATCGTTTCACCCATGACAGCACCGATACCATTTGTCCACATTGCTCGAAAACCTGTACATCGCGTACAGCATTGCGTGCCCATATTAAATATGCCCATAAATTGACCACAAATCTCCAGTGCACATATTGTGAGAAAAGTTTCAAACAACAGCGAAACTTGGAGGAGCATATGGCCATCCATACGGGTCTCCAGCTATATAATTGCCCGCACTGCCCCAAGGAATGCCGCTCGCGCTCCAATATGTATGTCCATATTAAGCAAAGGCATGCGGATGAATGGCTTAAAGCCAAAATGGCGCGTTCCCATAATCCGCAATTCAAGCCGCATACCCAAAGCTGA
Protein Sequence: MICRLCLRSINANTAVFLFETNETLAETRLVKMIAKFLQLEIMPDDSVSTSVCTVCCEHLEDFNSFWQLVEQKQGTLKKEFLTVDVDCGIMKWSSGVGEMDVVDVNADELPVVSVNMDEDEKPLPLDMHNLSLLGSVLDVNVDGQDEELEEEMPPVLIKKQKPDYNSDDNENEEEDEDEDDEDEKPMLEASESEFGEADIADAEPLGDDSSDDEPLVKLVMQSNNQKPKRKYTKNKRHLSLAMELKDLLDEDCSSKLLSHRRRKGAQQSRRDSPTETQETELQAALERKPKGCSRAQLTKRYEEVIASYMSANCDLCDFSGKFLSELKTHFQEVHQREFYIKCCNKIFTRASKLMDHIRKHVNPKLFTCSICNKSLNSQDYLATHIETVHNKVDQIGKVLKFPCPKCERTFSSERRLTNHLAKHDTDQLEHSCDICQKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECTICGVWLKNEHSLRLHRFTHDSTDTICPHCSKTCTSRTALRAHIKYAHKLTTNLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPHTQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00591271;
90% Identity: iTF_00556000;
80% Identity: -