Basic Information

Insect: Drosophila nebulosa
Gene Symbol: ZNF589
Assembly: GCA_018150735.1
Location: JAECWO010000001.1:15841248-15842909[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0016 0.11 13.0 1.1 3 23 179 199 178 199 0.98

2 12 0.012 0.84 10.2 6.6 3 23 209 229 205 229 0.94

3 12 2.4e-05 0.0017 18.7 4.2 1 23 235 257 235 257 0.98

4 12 1.1e-05 0.00083 19.7 5.8 1 23 263 285 263 285 0.99

5 12 1.9e-05 0.0013 19.0 0.3 1 23 291 313 291 313 0.95

6 12 2.3e-06 0.00016 21.9 2.5 1 23 319 341 319 341 0.98

7 12 1.5e-07 1.1e-05 25.6 1.6 1 23 347 369 347 369 0.99

8 12 2.3e-06 0.00016 21.9 7.7 1 23 375 397 375 397 0.99

9 12 3.6e-06 0.00026 21.3 0.6 1 23 403 425 403 425 0.97

10 12 1.4e-06 0.0001 22.6 1.2 2 23 434 455 433 455 0.98

11 12 0.016 1.2 9.8 1.1 1 23 474 496 474 496 0.98

12 12 1.3e-06 9.6e-05 22.6 4.5 1 23 501 524 501 525 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0016	0.11	13.0	1.1	3	23	179	199	178	199	0.98
2	12	0.012	0.84	10.2	6.6	3	23	209	229	205	229	0.94
3	12	2.4e-05	0.0017	18.7	4.2	1	23	235	257	235	257	0.98
4	12	1.1e-05	0.00083	19.7	5.8	1	23	263	285	263	285	0.99
5	12	1.9e-05	0.0013	19.0	0.3	1	23	291	313	291	313	0.95
6	12	2.3e-06	0.00016	21.9	2.5	1	23	319	341	319	341	0.98
7	12	1.5e-07	1.1e-05	25.6	1.6	1	23	347	369	347	369	0.99
8	12	2.3e-06	0.00016	21.9	7.7	1	23	375	397	375	397	0.99
9	12	3.6e-06	0.00026	21.3	0.6	1	23	403	425	403	425	0.97
10	12	1.4e-06	0.0001	22.6	1.2	2	23	434	455	433	455	0.98
11	12	0.016	1.2	9.8	1.1	1	23	474	496	474	496	0.98
12	12	1.3e-06	9.6e-05	22.6	4.5	1	23	501	524	501	525	0.97

Sequence Information

Coding Sequence: ATGGAAACCACACAACGCTCTCAGCAAGAAAATGAGCCGCATTTTTGTCGTTTGTGTATGGATAGTTCCGTGACGCTGATTGAGATCTTTTCCAAGCTCCAGTCAACGGATCATTGCGATCCCACCCTGGCCGATATGATAAATGACATATTAAAGGAAAAGTGTCATGTGAAGCGGGATACACTGCCTCAGCATATTTGCCATGATTGTGTTTTCGCAGCCGAAAATGCTTTTCATTTTAAACAACGATGCGAACAAAGTTTTAGTCATTTCTCTCGACTCTTGAAAAATAATGGAAAGATGGATACAGAAAACCCAAGCTGTCACTTACAGGTTGAGGAAGGATTCAGCGAAAAAGTAAAGGAGACTGATATATATAGTAACAAGGACATGGTTGCAAGCTATCAGTTTGTAGAGGTGATGTTAAATGAAAAATCAAAGCTAGACGAACTTCCACCGCTTAGGAATATAGCTGATCCCGAGGCAGATATAGATATTCTCAAGGCTGAGGAGCAAGAGATGCAATCTCTGCTCTGTTCGGAGTGCGGGATGACCTTAAAGTCGAAAACCTCCTTTAGCCAGCATATGGGTCGACATAAGAAGGTTGTAGATCGTTGTCATCTCTGCGAAACTTGCGGCAAGGATTTCAAATGCAAGGCGCAGTTAATTATCCATACACGGACCCATACAGGCGAACGTCCGTTTAAGTGTCTCCATTGCGACAAGACTTACTCGCAACGTACCACACTGCGTATGCATTTGGTTACCCATGGCAAGGAGCGACCCTTTAAGTGCCAACAATGTGATAAAACCTTCTATCTACATCGCAATCTAAAAGCTCATCAGCGACGGCACAACGGCTTGCGTCCCTTCCTGTGTCCTAGCTGCCCATTGGCTTTTACCAAGAATGCCAATCTAAAGACCCATCTGCGTCTGCACACAGGCGAAAAGCCCTTTAAATGTTCCAAATGTGATCTGAGTTTCCGACAGAATCAACATTTAATCATTCACCTGCGGGGCCACAATGATGATCGGCCCTACAAGTGCTTGCAATGTGACAAATCCTTTTTTGTCAACGCAAATTTGAAGAAACACATGCGTGTCCATACTGGAGAGAAGCCATTCAAGTGTGAAACCTGTGGCCAGTCATTTTCGCACAATCACCATCTGAAGTCCCACTTGCGCATTCACACGGGCGAACGTCCCTACAAGTGCACGGAGTGCGACAAGCTATTTGCATCAAATCAATCCCTGCAAAAACATCTTATCTGGCACAGGGATAATAAGGATAAGCCCAACAAGTGTCCATATTGCCCGAAGGGATTTGATCAATTCAGAAATCTTAAGTATCATCTTCGCACTCACAAGGCATTAGTTAATGTGGAGTCCGATGGTCTGGAGGAGAAAAAGAAGTCACCTCATAAATGTCCTTATTGTGATGATGGCTTTGAGTTCAAGAGAATACTGGAAAAGCATTTGATTACACATAAGGAGCGACCCTATCAATGTGAACAATGTCCCAAAGGATTCTCCCATCGTCAGACCTTGAAGAAACATATTAGGTCCATACACCATAATATCGAGGGATAA
Protein Sequence: METTQRSQQENEPHFCRLCMDSSVTLIEIFSKLQSTDHCDPTLADMINDILKEKCHVKRDTLPQHICHDCVFAAENAFHFKQRCEQSFSHFSRLLKNNGKMDTENPSCHLQVEEGFSEKVKETDIYSNKDMVASYQFVEVMLNEKSKLDELPPLRNIADPEADIDILKAEEQEMQSLLCSECGMTLKSKTSFSQHMGRHKKVVDRCHLCETCGKDFKCKAQLIIHTRTHTGERPFKCLHCDKTYSQRTTLRMHLVTHGKERPFKCQQCDKTFYLHRNLKAHQRRHNGLRPFLCPSCPLAFTKNANLKTHLRLHTGEKPFKCSKCDLSFRQNQHLIIHLRGHNDDRPYKCLQCDKSFFVNANLKKHMRVHTGEKPFKCETCGQSFSHNHHLKSHLRIHTGERPYKCTECDKLFASNQSLQKHLIWHRDNKDKPNKCPYCPKGFDQFRNLKYHLRTHKALVNVESDGLEEKKKSPHKCPYCDDGFEFKRILEKHLITHKERPYQCEQCPKGFSHRQTLKKHIRSIHHNIEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00604247;
90% Identity: iTF_00604247;
80% Identity: -