Dnav002419.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila navojoa
Gene Symbol
L
Assembly
GCA_001654015.2
Location
NW:391837-432251[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 9.9e-06 0.00057 19.7 2.9 1 23 324 346 324 346 0.98
2 17 0.34 20 5.4 6.2 1 23 352 374 352 374 0.97
3 17 1.6e-07 9.4e-06 25.3 3.2 1 23 380 402 380 402 0.99
4 17 1.2e-05 0.0007 19.4 0.4 1 23 408 430 408 430 0.99
5 17 0.013 0.77 9.8 0.2 2 23 511 535 510 535 0.93
6 17 0.0003 0.017 15.0 0.2 2 23 563 585 562 585 0.96
7 17 0.06 3.5 7.8 0.7 1 23 662 684 662 684 0.97
8 17 0.027 1.5 8.9 0.0 2 23 692 713 691 713 0.91
9 17 0.02 1.2 9.3 1.2 3 23 724 746 721 746 0.86
10 17 3.2 1.8e+02 2.4 1.0 2 23 782 804 781 804 0.95
11 17 0.0025 0.14 12.1 1.1 1 23 849 872 849 872 0.97
12 17 0.0063 0.36 10.9 1.6 2 23 1051 1073 1050 1073 0.96
13 17 0.11 6.4 6.9 0.1 1 23 1079 1101 1079 1101 0.92
14 17 0.25 14 5.9 0.6 2 23 1109 1130 1108 1130 0.96
15 17 0.3 17 5.6 1.3 1 23 1230 1252 1230 1252 0.94
16 17 0.019 1.1 9.3 0.0 1 23 1262 1284 1262 1284 0.96
17 17 0.00022 0.012 15.5 1.2 1 23 1289 1311 1289 1311 0.97

Sequence Information

Coding Sequence
ATGTCGAGGCGCAAACAGGCCAAGCCGCGCGCCTGCCTTAAACTTGGCGAAAAGGAGGATGAAAACGTTGGCGATGCCGCCAAGGCGGCCAAAGCCTCCGATTTGCTGGAGCCCAAAGAGGAGCTGCTCAGCGCCGATGAGGAGGAGagcgaggaggaggatgatGAGCTAACTGGCGAtgaggaggaggtggaggagggGACGGCTGGCAAGGCAAAACTGATGCAGGCGCGAGTGCCCAATGaatcacagcaacaaaactggcagccagcagctgatgctgcaacagcaacaacagcaacaacaactgcaacaacatctgcaacaactgcaacaacagcaactgcagctgaagtACAACACCCTGGAGACActgagccagaggcagaggagACAACGTCTCTGAACGTGGCCAACGGGCACTGCAAGACAGAgccaacagttgctgctgccgctgAAGATGCCGAGGACGAGCTGGAAGATGATTTGCTTAGCCTGAGCGGCGATGAGGACTACGACGATGATGAGGAATTGCAAAGCCTGGACAGTTTCTATTCGGataTGTACAGCACGCACACATCGTCGAGCTATTCGCCCAGCATCTCCGATGGCACTTTGACGCCCAActcacagctgcagcagccgcagtcgcagcagcagtcgcagtcgcagcagcagtcgcagcaggcCGGCTCGGAGGAGACGGGCGAGGAGTCGGCCAAGGCGAATGGCGATACGGCACAGCAAacggagctggagcaggagctgaacAAACCGAAGCGACCGTCACAtttgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATAGCGAACAAGCTGCGAAAAATCAATAAGGATGCCAAGCTGGCTGcaggacaaggacaaggacatGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCACGGCTCGGCTACCTGAAGCATCACGTACAGaGTCATGCCGAGCATTTGCCTTTCAAGTGCGAGTACTGCGCAAAGCTGTTCAAGCACAAACGCTCCCGAGATCGCCATAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGTGATCATCTGAAGATCCACATGAAGACGCACGACATACAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCAATCCTCGCAGCTGGCGGCAATCCCAATGCGCTCAATTACAGTCCACGCTCCACGGGCTCCGCCTCGATCTCGAGCAATGGGAGCCTGCATAAGCGACGCTACGCCTTGGCGCTGGCCTCCGACAGCAGTCCCAGTCGGCTGGAGTTTCCCAAGCGGGCGCGTGGCCAGCtgacggccacgcccacggcgACAACGATAGCCACGCCGACGCCCAcgccgctgctgcgctgcagctACTGCCCCAAGGCGACGGAGTTCAGCAGCCTCGAGCAGCTCAACGCGCATCTGCAGAGCACacacgagcagcagccgcagccccagcagcagcagcagcagcagcagtcgaaggAGTCGGATGGCCAGACGAATGGCTTCCAGTTGAGCTGCGAATACTGCACGATGAAGTTTGTGAATATCGCTGCGCTGTTCCAGCACATGAGAGTCACGCACTTGGATCGCCTGAGCAGTCCCAATTCCTACTACGAGCACTTCCATCGGCTCGGCTCGCCGCAGTCGAAGCTGAAGTCGGATCTGGCGCCAGCGGAGAAGCCCGAGCAGGAGCTGCCCACCGATctgagcagcaacaagcgcCGCCCGCTGACCTCGCccacgcagcaacagcaacagcagcagcagcagcagcagtcggcgCCAGCTCCTCCGCCGCCTCCTGGCATCTTCTTCTGCAATCAGTGCAACGCCGGCCTGCCGGACTTTGAGAGCTTCCGCAATCATCTGAAGAGCCACATAGCCGAGGGCATGCAGCTGATCTGTCCGCACTGCGGGCTCAGTCTGCCCGAGCAGGGCGAGTACGAGCGCCATGTGGTCGCCCACTTTCTGATCAGCAGCTCCGAGTTCAattgctgcagcgccagctgTGGGAAGTCCTATGCCAAGGCGGAGGAGCTGCATCAGCATCTGCTGGCCGAGCACGTCCAGACGATGCTCAAGTGTGTGCTCTGCTCGGAGCTCTGCGAGAATCGCATGTCCATGCAGCTGCACCTGGCCTGCGCCCACAGCCAGGAGTCGAagctgctgcgctgcagcgCCTGCCTGGAGCTCTTCCGCAACGATGGCGACTTCCACGTGCATGTGAAGACACGCCATCAGCTGGGCAACCAGGCCAGCCTGCCCGGTAATCCACCTGCGCCGGCCAATCCGCTGCAGTGCATGTTCTGCCGCGCCGTCTGCTCCTCGGAGCTGGAgatgcatttccatttggcgGCGCATGCGCGACAATTCCGCTGCCCCAGCTGCCCGGAGACCTTCCATGTGGAGTTCCTGCTGGACAGGCACATGCAGAGCCAGCACGGCGGCATCAAGGACAAGGAGTCGCCCGTGCCGGGCGGCATGGGCAGCTTGTATGTGaatgcgctgctgccgccactggcagcggctgctgctgccgctgccgcagccaaTAAtgccgccaacaacaacaacaacaacaataataatattgattacaATGTCGCCTTCAAGGGTCTCTTTGGGGGCAGCAATCCGCCGGGCAAGTTCTACAACAGCCCGCTCCAGGTGGACACCAAGCAGAGTCCGCATCCTGCTCTCATGTACGGCCTGAGCCAGCGCTACTTGATGGAGATGTACGCCGCCAAGGCCAATTCCCCAGCCGCGGAGCTGCCCACGCCGCAGGCCGTGCAATccgcgacagcagcagcagcagcagcagcagcagcagcagcagcgagcggcagcaacagcagcggcagcaacaacaacaacagctacagctgcggCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCCGAGCTCCATTCGCATCGCAAGCTCGCCCACAATCTGAAGACGGGCGTCAGCCTGCGCTGCGCTTACTGCTCCGGCAACTACaagagccgagccgagctggagcagcacatGAAGAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCCGCCATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAGTCCGGCAAGTGCGCCCACTGcggccagcagctggagcacgTGGCCGCCTTCCGTGCCCATCTGAGCGAGCATGGCAACGACGGCAATCTGCCCATGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCCGAATTCGAGCTGAGTCTGCACGCCAAGTTCCACACCAAGTCGCCCAGTTGCAACAGCCTGCAGGAGCCCGTCTGTGCCCTGTGCCTGGAGCCGCTGCCGGGGGCGGGCGAGACGGCCAAGTTGTGCGACAAGTGCTGCCGCAAGCACAATCTGAATGGCAAGCGCAAGGAGCAGGTGCAGCCTACGGCCATCGCTGGcccagccgccgccgccgccgcatcAACTGGCGCCTATCTGGAGCATCGCTGTAATCTGTGCAAGATGATCTTGCCCCATGCCCAGAAGCTGCAGGAGCATCTCGTCGAGCACACCTTCGCGGGCACCGAGCAGCGTGGCTACAATTGCTACATCTGCTCGGCCGTGTTCACGGCGCCCGCTGGCCTGCTCGCCCACATAGCGGAGCACGGCACACGACCGTACGACTGCAACCTGTGCCCGGAGAAATTCTACTTCCGTGCCGAGCTGGAGCATCATCAGCGAGCGCACGAGCTGCACGCTCAGccggcagcaatggcagcagcagcagccgcagcagcagcagcagcagcaggagcaacacgTCCACCTAAGCAGGAGACGCACAGCTCGACGGCCAGTTCCCCACTAACGCTCAGTCCCAGCCATGTCAAGCAGGAGCTATACGAATCGGATCCGGCGAATTCGCCCAACGACGCGGAGCTGCCTccggcgcagcagcaggaggaggaggagtacaTTGAGGTGGAGCAAATGCCGCAGGAGACGCTGCGAGCTGGCGAACTACTCAGCACCGAGcgttccagcagcagcgcctaa
Protein Sequence
MSRRKQAKPRACLKLGEKEDENVGDAAKAAKASDLLEPKEELLSADEEESEEEDDELTGDEEEVEEGTAGKAKLMQARVPNESQQQNWQPAADAATATTATTTATTSATTATTATAAEVQHPGDTEPEAEETTSLNVANGHCKTEPTVAAAAEDAEDELEDDLLSLSGDEDYDDDEELQSLDSFYSDMYSTHTSSSYSPSISDGTLTPNSQLQQPQSQQQSQSQQQSQQAGSEETGEESAKANGDTAQQTELEQELNKPKRPSHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTATPTATTIATPTPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQPQPQQQQQQQQSKESDGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFHRLGSPQSKLKSDLAPAEKPEQELPTDLSSNKRRPLTSPTQQQQQQQQQQQSAPAPPPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQGEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDGDFHVHVKTRHQLGNQASLPGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVPGGMGSLYVNALLPPLAAAAAAAAAANNAANNNNNNNNNIDYNVAFKGLFGGSNPPGKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPAAELPTPQAVQSATAAAAAAAAAAAASGSNSSGSNNNNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQVQPTAIAGPAAAAAASTGAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPAGLLAHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELHAQPAAMAAAAAAAAAAAAGATRPPKQETHSSTASSPLTLSPSHVKQELYESDPANSPNDAELPPAQQQEEEEYIEVEQMPQETLRAGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
iTF_00502755;
80% Identity
-