Basic Information

Insect: Drosophila navojoa
Gene Symbol: ham
Assembly: GCA_001654015.2
Location: NW:5527-40158[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.49 28 4.9 0.0 2 21 393 412 392 415 0.87

2 9 0.032 1.8 8.6 2.3 1 23 422 445 422 445 0.91

3 9 1.5e-07 8.7e-06 25.4 1.7 1 23 451 474 451 474 0.96

4 9 2.9e-07 1.7e-05 24.5 1.5 1 23 480 502 480 502 0.97

5 9 7.4e-05 0.0042 16.9 3.8 1 23 508 530 508 530 0.97

6 9 0.0048 0.27 11.2 2.0 2 21 538 557 537 558 0.94

7 9 5.7e-09 3.3e-07 29.9 1.3 1 23 1048 1070 1048 1070 0.99

8 9 3e-07 1.7e-05 24.5 0.9 1 23 1076 1099 1076 1099 0.97

9 9 1.3e-05 0.00073 19.4 3.9 1 23 1105 1127 1105 1127 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.49	28	4.9	0.0	2	21	393	412	392	415	0.87
2	9	0.032	1.8	8.6	2.3	1	23	422	445	422	445	0.91
3	9	1.5e-07	8.7e-06	25.4	1.7	1	23	451	474	451	474	0.96
4	9	2.9e-07	1.7e-05	24.5	1.5	1	23	480	502	480	502	0.97
5	9	7.4e-05	0.0042	16.9	3.8	1	23	508	530	508	530	0.97
6	9	0.0048	0.27	11.2	2.0	2	21	538	557	537	558	0.94
7	9	5.7e-09	3.3e-07	29.9	1.3	1	23	1048	1070	1048	1070	0.99
8	9	3e-07	1.7e-05	24.5	0.9	1	23	1076	1099	1076	1099	0.97
9	9	1.3e-05	0.00073	19.4	3.9	1	23	1105	1127	1105	1127	0.98

Sequence Information

Coding Sequence: ATGACGTCTCTGCTTGAGATTATAATGCGATCCAAAGCGATTGCTAGAAAATTCAGTCAAGGCTCTAACGGCGACGACTACGATCCGAGCGTCGTGCgccaccatcatcatcatcatcatcatttggATCTCAGCAGTGGAGCGCCGCCCTTTGGTCCGCTGCCGCCGGCGCACTTGACCTCCAGCCAGGCTCGGCCCGAGGAGACGTTCGGTCGCCATCTGCCGCCAACGATATCCCCGCCCCCTGCGGCGCTGCTTCAGCAGCCCTCGCAgtcggcgtcgcagtcgcagtcccttcagcagcagccatcgctgccgccgccgccgcatttagcattgcatttgcagcaacagcgattGCAACGCTCGCCGCCCGCTTCAGTCTCTGCCTCGATCTCTGCctccggctctggctccggctccggctccggttCTGGTTCCGGCTCTGGTTCCGCCAGCGGCACCAACATGGAGCACCTCTTCAGCGACAAGACGCAGGAGTTTCTAATGCAGATGGCGCGCCTGCGCGACCCCTTTTGTGATATGGACATTCGTGATAATGGCGTCTATGCCAAGACCGATTTACCACGCGACTCCCGCTACGGACCCTTTCCCATGCACCTGTGCCAGCAGCCCAGCGATCGCCACTTGGCCTGGGAGgtAATTGCCGGACCGCTATTCCACGGCTGGCTGGAGCCCTCGGCGGATGTGGCCACATGGCTAAAAAAGATACGCAACGCCCAGAGCGATGAGGCTGAAGAGGCTAATTTAAGGAATTTCGTTGTCGATCGCTGTcTGTGGTACGAAACGAAACGGGATATTAGTGCAGGCGCTGAAATCGTGGTCGATCCCCGCTCCCGCACGCCCTACGACATCAGCGAGAGCCTGCGGAAtggcagcatcagctgcagcagcagtggcagcagcagcgcggcagcagtggcagcaactgcagcagccgcagccgccgccgctgccgcagcagccgccatgGCAGCcgctagcaacaacaacaacaacatcaacaataacaataacaacaacaatagcgatGATCGCAGCGATCGTGATAACGgCTTTTACAGCGGCGACGAATTTGCGAAGGATAAGAAAAACATATCGATAAACAGTCAGGTCGATAACGATTTCACAGACGACGAGAACGGTTTCGATATACGCTGTGAGGTCTGTGATAATGTCTATACGGATTTAGAACGCCTGGACGATCATCTGGTGGGCGCGCATCACTTTAAACGTGGAGAATTCGCCTGTGAGTTGTGCTCCCAACATTTCTGCCATCGTCCGTTGCTGATCAAACACGGAGCGATCGCCCATAATAACATAAGGAAATATTCCTGCGAGAATTGTTCCAAGGTATTCTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCATCCGTGTCCGGAGTGCGGTAAAACATTCGCCACATCGTCCGGGCTaaagcagcaccagcacatCCACTCCTCGGTCAAGCCGTTCGCCTGCGAGGTCTGCTTCAAGGCCTACACGCAGTTCTCCAACCTCTGCCGGCACAAGCGCATGCACGCCGACTGTCGCATGCAGATCAAGTGCCAGAAGTGCAAGACGAGCTTCAGCACGGTCACCTCGCTCTCCAAGCACAAGAAGTTCTGCGACAGCTCCGACAGCTTTCGCAGCGGGCCACAGAGTCGCCTGGAGCATcatcagcaccagcaccggcagcagcagcagcagcagcaccaccaccaccagcaccagcaccaccaacaccaccagcagccACCTGGTGCGCATCAGCGactcgctgccgccgccgccgctgccgcagccagcagcaacagcagcgacacaGCCGCCATGGCCACGCCTCCGAATCACATGTTCACGATGCATCCCACGCACTCGTTCTTTCCGGGCTTTCCGCCGTACGCGCTGCCCAACTTCTTTACGAACTGCCGGCcccagccgctgctgccgcacaTGTTTCCCGGACCGCATCTGGGCGAGATGGGGCGCGGCCTGGTGCCGCCGCTGGTCTCGCCGAACGCTGccttccagcagcagctgcaggcggcgATGAGCCTCAAGTCGGAGTCGCCGCGCCTCAAACGCGAGTCCAGCACGCCGGAGCGCAAGCATCCCATCAAGACCGAGCTGCAGCCCAgcgaggatgaggaggaggagcaggaggagtcCAATGCCTATGAGCGCCTGGACTCGAGCAAGGAGTCGAAGAAGCCAATGGCCGAGTCAAAGCCGGAAGCTAGCGGAAGTGAGCAGCCAGCACAAGGCGAGGATCGGGAGCAGGCCCAAGATAATGATAACGACAATGagaatgacaatgacaatgacaatgagaatgagaatgataaTGACATTGACAATGATAGGAAATCTATTGACATAATGAGCACACCACCGCCCGCTGAAACGGAGGcgccggagccggagcaggatAAGAGCGGTGTGGATCTGCTGCCACTGGATCTGTCCGTCAGCCGCAAGCGGCGCAGCTCACTGTGCACGGCCAGCACGCCCGTGCCGCTGGCCATGTCGCTGTCCAGTCGCACGTCCACGCCCGCGCTGGAGATCGCGGAGCCGCCCGTCAAGCTGATGAAGCACAGCTCGGGCGAATCGTCCACCTCGCACCAGTCCTTCAAGGGTAGCAGTCCCACGCCCAGTGTCAGCGCCTCGCCCGGACccacgccctcgccctcgccgcCCATCAGCACGGGCGGCGAGCTGAGCAGCATGTCCGAGAGTGCGGCGTCCGCCGCCGCCGTGGGCGCTGCctcggcggcggctgcggcggccTCGGTGATGGCCTGCCCGCGGCAGCTGCAtccccagctgctgctcgaggaGTTCTATCGCTCGCGCTTCAATACGCCACCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGCCACTCAAATCGCCGGCTGCTggcatcagcagcggcagcagctcgcGTCATCTGCCGTTTCCGCCCGAGCACAATTTCCACGAGGCTCTGCGAGCCGCCGGCctggccgccgccgctgccaatgcctgcagcagcggcgccagcGTCGTCGCCGCCAACGGCGGCAAGCTCAAGGACCGCTACACCTGCAAGTTCTGCGGCAAGGTCTTTCCGCGCTCCGCCAATCTCACCCGGCACCTGCGCACCCACACCGGCGAGCAGCCGTACACGTGCAAGTACTGCGATCGCGCCTTCAGCATCTCCTCGAATCTGCAGCGGCACGTGCGCAACATCCACAACAAGGAGCGGCCGTTCCGCTGTGAGATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCATCTGAAGAAGCATGAGGCGGATGCGGCCGGCTTCGAGTACAACGACTCGCCCAGCTCGAATGAGGCTGGCGATCGGGAGGAGGCCTGCTTCGATGACATTCGTTCGTTCATGAAGCGCGTCTATACGCCCACCAGTCTGGGCGGGGCGGATGGGGACACCGAGGAGTATGCGGGCAGCGATGATCAGTTGTCCGTGTCGACGCGTCACTCCGTTAGCTTTGACAaggagctgctggccaatggcaacaacaacaacaccaacaacaacaataacaacaacaacaacagcagtagcaccaacagcagcagcagcagcaacaacaacaacaacagcagcagcagcaatccgACTGGTCTGGGCGAAACGATCGCCGTGAGCACTTAA
Protein Sequence: MTSLLEIIMRSKAIARKFSQGSNGDDYDPSVVRHHHHHHHHLDLSSGAPPFGPLPPAHLTSSQARPEETFGRHLPPTISPPPAALLQQPSQSASQSQSLQQQPSLPPPPHLALHLQQQRLQRSPPASVSASISASGSGSGSGSGSGSGSGSASGTNMEHLFSDKTQEFLMQMARLRDPFCDMDIRDNGVYAKTDLPRDSRYGPFPMHLCQQPSDRHLAWEVIAGPLFHGWLEPSADVATWLKKIRNAQSDEAEEANLRNFVVDRCLWYETKRDISAGAEIVVDPRSRTPYDISESLRNGSISCSSSGSSSAAAVAATAAAAAAAAAAAAAMAAASNNNNNINNNNNNNNSDDRSDRDNGFYSGDEFAKDKKNISINSQVDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFACELCSQHFCHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCQKCKTSFSTVTSLSKHKKFCDSSDSFRSGPQSRLEHHQHQHRQQQQQQHHHHQHQHHQHHQQPPGAHQRLAAAAAAAAASSNSSDTAAMATPPNHMFTMHPTHSFFPGFPPYALPNFFTNCRPQPLLPHMFPGPHLGEMGRGLVPPLVSPNAAFQQQLQAAMSLKSESPRLKRESSTPERKHPIKTELQPSEDEEEEQEESNAYERLDSSKESKKPMAESKPEASGSEQPAQGEDREQAQDNDNDNENDNDNDNENENDNDIDNDRKSIDIMSTPPPAETEAPEPEQDKSGVDLLPLDLSVSRKRRSSLCTASTPVPLAMSLSSRTSTPALEIAEPPVKLMKHSSGESSTSHQSFKGSSPTPSVSASPGPTPSPSPPISTGGELSSMSESAASAAAVGAASAAAAAASVMACPRQLHPQLLLEEFYRSRFNTPPFHFLGQMGGRPGFEPLKSPAAGISSGSSSRHLPFPPEHNFHEALRAAGLAAAAANACSSGASVVAANGGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCEMCDRCFGQQTNLDRHLKKHEADAAGFEYNDSPSSNEAGDREEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRHSVSFDKELLANGNNNNTNNNNNNNNNSSSTNSSSSSNNNNNSSSSNPTGLGETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00568407;
90% Identity: iTF_00540519;
80% Identity: -