Basic Information

Insect: Drosophila navojoa
Gene Symbol: -
Assembly: GCA_001654015.2
Location: NW:198500-203703[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.29 16 5.7 5.6 2 23 333 355 332 355 0.96

2 17 0.0059 0.34 10.9 1.6 2 23 398 419 397 419 0.94

3 17 4.7 2.7e+02 1.8 3.0 2 17 430 445 429 456 0.75

4 17 0.021 1.2 9.2 0.3 3 23 489 509 487 509 0.95

5 17 0.0022 0.13 12.3 0.3 1 23 517 540 517 540 0.98

6 17 0.00035 0.02 14.8 0.3 2 23 545 566 544 566 0.97

7 17 0.35 20 5.4 0.0 1 20 574 593 574 595 0.93

8 17 8.2e-05 0.0047 16.8 0.4 1 22 614 635 614 638 0.90

9 17 0.0082 0.47 10.5 1.7 1 21 643 663 643 664 0.94

10 17 0.015 0.87 9.7 0.2 1 23 683 708 683 708 0.96

11 17 0.0084 0.48 10.5 1.6 2 23 724 746 723 746 0.93

12 17 0.00054 0.031 14.2 0.2 2 23 752 774 751 774 0.92

13 17 0.0075 0.43 10.6 0.3 2 23 778 800 777 800 0.96

14 17 1.5e-05 0.00084 19.1 2.1 1 23 806 828 806 828 0.98

15 17 0.0084 0.48 10.5 0.6 1 23 832 855 832 855 0.93

16 17 0.0001 0.0058 16.5 1.0 1 23 861 884 861 884 0.97

17 17 0.00051 0.029 14.3 0.8 1 23 888 916 888 916 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.29	16	5.7	5.6	2	23	333	355	332	355	0.96
2	17	0.0059	0.34	10.9	1.6	2	23	398	419	397	419	0.94
3	17	4.7	2.7e+02	1.8	3.0	2	17	430	445	429	456	0.75
4	17	0.021	1.2	9.2	0.3	3	23	489	509	487	509	0.95
5	17	0.0022	0.13	12.3	0.3	1	23	517	540	517	540	0.98
6	17	0.00035	0.02	14.8	0.3	2	23	545	566	544	566	0.97
7	17	0.35	20	5.4	0.0	1	20	574	593	574	595	0.93
8	17	8.2e-05	0.0047	16.8	0.4	1	22	614	635	614	638	0.90
9	17	0.0082	0.47	10.5	1.7	1	21	643	663	643	664	0.94
10	17	0.015	0.87	9.7	0.2	1	23	683	708	683	708	0.96
11	17	0.0084	0.48	10.5	1.6	2	23	724	746	723	746	0.93
12	17	0.00054	0.031	14.2	0.2	2	23	752	774	751	774	0.92
13	17	0.0075	0.43	10.6	0.3	2	23	778	800	777	800	0.96
14	17	1.5e-05	0.00084	19.1	2.1	1	23	806	828	806	828	0.98
15	17	0.0084	0.48	10.5	0.6	1	23	832	855	832	855	0.93
16	17	0.0001	0.0058	16.5	1.0	1	23	861	884	861	884	0.97
17	17	0.00051	0.029	14.3	0.8	1	23	888	916	888	916	0.89

Sequence Information

Coding Sequence: ATGTCGGAAAatccaaaagcaaacaacgaAAATGGACCTAGCTGCCTGCATTGCAGCGTGCACAGTTCAAAGCAGCAATATCAAGAAATTTTTGATGAAGTGGGCGTCGAAATCGAGCTCGCTGATCTTCTGgcaaaatatttccaaatcGTTGTCAAGCCCGATGCCCATAAATCGCAATTGCTGTGCCAAGAATGTGTAAACACGCTAATACGCTTCTTTGACATAGacgagctgcagcggcagcaggatgCCGCcaatgcagaaaaaaagaCTGCCAAGCCGCAGGAGGATTTACCACCAAGTGCTACTAAAAAGGTAGAGAAATCCGCTAAAAAGGTGACGCCGACGTCGCCAAAGACAAAGAGCGTTGCTTCTCCAGTCAAGAATTTGCCAAAACCCGAAGCAACTTCTCCAATTGCCGTGGCTACAACTGCAGCAAAAGCCTCTAATAAAATCTTAACAGTTCTGCCCAATCGTTTGCCCGATAAGCCCAAGGAGATTGTTACACGAAGTGCCAAAACCAAGGCTGGCGCGGCAGATCAGGAACAAATCAGCGCGCTTATACGTGACATTCTGGATGATGAAGAGCCGCAGGCCGATGATAAATTGACCGAGGCAGCACCCACAGTTGGGCAGCTGGAAAAGCAAACTGGCAAAAAGCAGAGACAGCAGGAGACAGTGGAAGAGCAGCTGGGACAGCTGGAGGAAGAGGACAACAATGATGAGCTGGAGTTTCTGCTGGAGCAAGATGATAACTCCTCCGATGCGGACGTGCGCCATTTCAAAGTTGAGCGCAAGGTCAAACGCGCCGCTTCACGTTCCTTGTCCCAATCGCAGTCGCAAAATGAAAGTCAAAGCGAGGATGAATCATTTAAAGTGGAGccctttaattttgttttaattaaagaatCTGACAACATTGGCGATCTGCATGAATATCTATCGACCGTGGTCAAGACCTGCTTTGAGACCTTGCAATTCGATTGGGCCACTGTCTGCCGTCATTGTTCGCTGAAATGCAGCAAATATGAAACTCTGCTCAGTCACATGCAGAAAAGTCATGAGCTGGCCGATGAGCGCTACAGTTGTCCCATTGAAGGCTGCACGGCGGAGGTGCAAGGACGCAAATATCTGGCCATGCATCTGGTGGTGCTGCATGCACCTGTGGCAGAAATCCCAATTTATGGCAAGTGTCCCGAGTGTAATATGACCTTCTCcaatatattgcaatataataaacacTCTTGCGCACACGTCATTAAAAAGCGTCGAGGCATGCGCTTATACTGTGAGATGTGTGGCCTGGAGTTTCCCTCGTGGAAGCGCTTTAATTTCCacaatcaatttcatttggagCGTCACAGACCGCGCGCTTGCTTCGTTTGCAATTTCGCAGACAACAACATCGATGAGCTCTTCCGCCATTTGTATTATGCCCACGAACCGGAGGGCACACTCTTTTGTGATCTTTGTGATCGCAACTTTCGTGATGCTGCCGTCTTTATGGAGCACAACAAATCGCATGCGAATGTCAGCAGCACCACCTACAGCTGCTCGGAGTGCAGCGCCAACTTTGAGACACGAGGACGTCTCAACGGTCATCTGCGCTCCGTTCATGGCAGCGTCATCAGCTGCGAGCTGTGCAGCCGCGAGTTTGCCACAGAGGCGACCTACAATCTGCATATGAAGACGCATTTGATCATCGAGCGTCAGGTGCACGTGTGCAGCGGCTGTGGACTGCTCAGCGATAGTAAAGTGAAGCTGCAGGCTCATGTGGAGGCGGAGGAATCGGCCTGCATTGGCTTGGAGACCTATGCGGAACTGTTGCGCAATGCCTACGTCTGTGAATATTGCTCGGCATACTTTAAGCAGAAGAGCGATCTGCGTGCGCATCGCGATTCGGGCGTGCATAAAGACGGACTCTTCATATGCCATCCGTGTGACAAGGCCTTTTCCGACATGAAACTCTATCGCCATCATTTGCGCAACTTTCAGCAACAGCGCTCAGATGTATTGCATCGCAAGCTAGAGATATGCATCTACTATATGTGCGATTATGAGGATTGCGCTGAGGCCTACATTAACTGGAACTCGCTGTACACACACAAGCGACGCTCGCACGATGCCATTGCGAGAAATGAGCCGCTGGTCAAGGAGAACGAATGGATCTGCCAGTTCTGCCATAAGCAATATAGATCCAAAATGTCGCTTTCGGTGCATGTGGCGCGAAGTCATAATAATAATAATGTCGTTTGTCCTCTGTGCAAGGCCTCCTATAAGGATAACGATGCTCTGACTAAACATCACGCCTACTGGCATGAGCCCATGGAATGCAGTTTGTGCCTGAAAGTGGTTAAAAATCGTCGCAATTACGACACCCACATGAATGTGGTGCATTCGAATAATAAACGCTACTCGTGCAGCGTCTGCCAGAAGGGCTTCTATCATAAGAGCGAAATGGAGGCGCATCAGCGGCTGCATAACCAATCGTATAGCTGCGACCAGTGCAGCTTCGTCACACGGAACAAGAAGTCGCTGTCGGTGCATGTGCTGGGCCAGCATTTCAAGCGTTTTGCCTTCGAGTGCAAGGCGTGCAACAAACGGTTCGGACGTCGCCAGGGCCTATCGAATCACATGCAGCGTGTGCATGGCTCACGTTATACGTGTCGCGACTTCTATGATGGTGGATGCAGCAAATCGTTTAGCTCGACGACGCAACTGAAGTTGCATGTGCGTAAGGTGCACAATGGCAGCATTTTCCTAGAGGATGATACAATGAAGGGTGACGAACTGGatgagctggaggagcaggagcacgagcaggagcagcagcaggagcaggagcaggagcagcagcaagaggaacaggaggaggaggagcaggagcaggagctggagcaggaggaggagcagaagAAAGTAAACAGCGATGGTCCGTCGTCTTCGAAGAAACGCTGCATACGCATCAATGCGAATACGCAAATCGAGTTTATTGGCAACTCAATGGAGACTAAGGAAACGGAGCTGTTTGAGGAGTTGCACGAGCCCAAGTCGAAtaagaggcagaggcaaaaatAA
Protein Sequence: MSENPKANNENGPSCLHCSVHSSKQQYQEIFDEVGVEIELADLLAKYFQIVVKPDAHKSQLLCQECVNTLIRFFDIDELQRQQDAANAEKKTAKPQEDLPPSATKKVEKSAKKVTPTSPKTKSVASPVKNLPKPEATSPIAVATTAAKASNKILTVLPNRLPDKPKEIVTRSAKTKAGAADQEQISALIRDILDDEEPQADDKLTEAAPTVGQLEKQTGKKQRQQETVEEQLGQLEEEDNNDELEFLLEQDDNSSDADVRHFKVERKVKRAASRSLSQSQSQNESQSEDESFKVEPFNFVLIKESDNIGDLHEYLSTVVKTCFETLQFDWATVCRHCSLKCSKYETLLSHMQKSHELADERYSCPIEGCTAEVQGRKYLAMHLVVLHAPVAEIPIYGKCPECNMTFSNILQYNKHSCAHVIKKRRGMRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCNFADNNIDELFRHLYYAHEPEGTLFCDLCDRNFRDAAVFMEHNKSHANVSSTTYSCSECSANFETRGRLNGHLRSVHGSVISCELCSREFATEATYNLHMKTHLIIERQVHVCSGCGLLSDSKVKLQAHVEAEESACIGLETYAELLRNAYVCEYCSAYFKQKSDLRAHRDSGVHKDGLFICHPCDKAFSDMKLYRHHLRNFQQQRSDVLHRKLEICIYYMCDYEDCAEAYINWNSLYTHKRRSHDAIARNEPLVKENEWICQFCHKQYRSKMSLSVHVARSHNNNNVVCPLCKASYKDNDALTKHHAYWHEPMECSLCLKVVKNRRNYDTHMNVVHSNNKRYSCSVCQKGFYHKSEMEAHQRLHNQSYSCDQCSFVTRNKKSLSVHVLGQHFKRFAFECKACNKRFGRRQGLSNHMQRVHGSRYTCRDFYDGGCSKSFSSTTQLKLHVRKVHNGSIFLEDDTMKGDELDELEEQEHEQEQQQEQEQEQQQEEQEEEEQEQELEQEEEQKKVNSDGPSSSKKRCIRINANTQIEFIGNSMETKETELFEELHEPKSNKRQRQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551740;
90% Identity: iTF_00549700;
80% Identity: -