Basic Information

Insect: Drosophila nasuta
Gene Symbol: -
Assembly: GCA_017165715.1
Location: Scf:15447-21801[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00035 0.022 14.8 0.1 1 23 170 193 170 193 0.96

2 14 0.0014 0.089 12.9 3.1 2 23 242 264 238 264 0.89

3 14 0.053 3.4 7.9 0.8 1 23 353 376 353 376 0.92

4 14 0.35 22 5.4 5.6 2 23 425 447 424 448 0.95

5 14 0.0028 0.18 12.0 0.5 1 23 513 536 513 536 0.88

6 14 6.4 4.1e+02 1.4 0.0 2 13 555 566 554 571 0.81

7 14 0.00059 0.037 14.1 3.3 2 23 587 609 587 609 0.96

8 14 0.0013 0.081 13.0 0.0 1 23 706 729 706 729 0.95

9 14 9.2e-05 0.0058 16.6 0.2 1 23 790 813 790 813 0.92

10 14 0.00099 0.063 13.4 2.2 2 23 863 885 862 885 0.97

11 14 0.0016 0.1 12.8 2.0 1 23 978 1001 978 1001 0.92

12 14 0.045 2.8 8.2 1.5 1 21 1053 1073 1053 1074 0.95

13 14 0.96 61 4.0 0.1 2 23 1128 1152 1127 1152 0.81

14 14 1.4 89 3.5 1.1 1 19 1170 1190 1170 1194 0.62

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00035	0.022	14.8	0.1	1	23	170	193	170	193	0.96
2	14	0.0014	0.089	12.9	3.1	2	23	242	264	238	264	0.89
3	14	0.053	3.4	7.9	0.8	1	23	353	376	353	376	0.92
4	14	0.35	22	5.4	5.6	2	23	425	447	424	448	0.95
5	14	0.0028	0.18	12.0	0.5	1	23	513	536	513	536	0.88
6	14	6.4	4.1e+02	1.4	0.0	2	13	555	566	554	571	0.81
7	14	0.00059	0.037	14.1	3.3	2	23	587	609	587	609	0.96
8	14	0.0013	0.081	13.0	0.0	1	23	706	729	706	729	0.95
9	14	9.2e-05	0.0058	16.6	0.2	1	23	790	813	790	813	0.92
10	14	0.00099	0.063	13.4	2.2	2	23	863	885	862	885	0.97
11	14	0.0016	0.1	12.8	2.0	1	23	978	1001	978	1001	0.92
12	14	0.045	2.8	8.2	1.5	1	21	1053	1073	1053	1074	0.95
13	14	0.96	61	4.0	0.1	2	23	1128	1152	1127	1152	0.81
14	14	1.4	89	3.5	1.1	1	19	1170	1190	1170	1194	0.62

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACATCGATGTTTTCGGCTGATTTTGAGGAGGGCGACGATGTGATTGATAATTATAATCATGGTAACAACGCAGACGAGTTTATTGGTGAAGAAGAGGAGGAGGAGCAGGAGGCTGATATCGATGAGATGGACGACGACAGGGAAGTGGAGCAGGAGAGGGAGGAGAGAAGGCGAAAGCAGAAGGGAAATGAGCCTGATGATGATGCGATATTTGATTTCGAATTGGAACCCATTATTAGCATTGCTGAACCGGAGTTGGAGCCACCTGTGCGACGCGAAACTGTCGCCTTGGCGCCTCCAATGGCAACCGCTGGGCCACCGGTGCGTGGCGTACACCGTCAGTCGCTTCCCGCATCGTTTGGTTCCTCGTTAATGCCACGAGGAGGGTCTGTGGTGGCAGCAACACCCCCAACGCGTCCAACAACATCGCAGATCAATGCAACCGATGAGAATGGCGTACCCATTAATTATGAATTGGGTGTCATTTACATTTGTCCCGCATGCGGGGCGGAGTATCGACAGCAGGACATGTGGAAGCGACACATGAACCAGATGCATCAGTATAACACGCGTAAGGGTCTCAATTTTGTGGCCATTGATAAGCTGTATCACCGGTGCCTGGAGTGCAACAAGCGAATTGCGATGCATAGTCGAGAGAATCTCTTGAAACACAAGTTTACACATTTGCCGTATCGCTGCACCAAGTGTTTCATCTGCAAGCGAGAGTACAAATATAGGCAGGACCTGATGGTACATCTGCGCATGGTTCACTGCGACGAGGTGGTGACTATGATGCGTGATGGTGACACTAGTGCGGGGCGTAAGACACGTGTGCGCGAGCCACGCACCGAGCAACCAAGAGCGGCGAGCTACGACGATGACGACGTTAAGCATGAGGAGCCGGTGGAGACAGAGGCAGATGCTATTGTTGTTGGAGAAGAGGTGGAGGAAAAGAGAAAGCACAGTATTCCAGCGGCAACTATCAATGGGAGCAGTGTGAGCAGTGCTGCTGAAATTTGCGAGGATTACATACACTATATGTGTCCTGACTGTGGCAACGATTGCGACACTCACGCACAGTGGAGTCAGCACATTGAGTTCGTTCATGATTATGTCAGCAGACGAGGCCTCAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTAGAGTGCAAGCAGTTTGTCATACCGAACACAATCAAGAGTTTGCGAGCTCACAAGTTTAGCCACTTATCACAACCTAATTGGATGCGCTGCAAATTGTGCTATAAAGGCTACACTGAGCACCACGAGCTGGTGACACATCTGCTCAAGCAGCATCACTTGGAGACATTAATGCCCGACGCCGAGGAAACGGATGAGCCCCTGTGCAATATCAGTGGCGGCGAAGTGGATGGCGAAGATAAAACTGCAACTGGCAATGATTGCGAGGAGGAATTGATAGCACATTGGGACGAAGCACCACGTCGCGGCGGACGCATCAGCAGCGACGACATGTACGAGCCACACATCGACTATTTGTGTCCACAGTGCGGTCGTGAGTTCATCGAGAAGAAACACTGGCGAACACATGTCGTCCAAGTGCATGGCATGAACGATCTGACCAAGTTGAACTTTGAGGTGATTAACGATCGTCAGCTGAAGTGCACAGAATGCGAGAAAATTATAACGAATGCATATGGTATACAGAATGCGCAGCAGCACCGCATTACCCACTTGCCATACAAGGCCTATGCTCGCTGTCGAAAGTGCCATAAATCGTACACGGATCGCAAGGGTTTGGTCAAGCATTTGGCCACATATCATCGTGTTGGCTACGAGCCACGTAAAGCGGCTGCTGGAGCAGTGCCCAGTAAGGTGCAGACGCCGCGAAAACAAATTGTCACTGTGGGAAATGAAACCTATGAGATCATCTACTTGGATGAAGAACAATCGTCGCCGGGCAATAATAACGTTAACGAGGAGAATGATTTTGGCGAACAGATGCAGGCAGATGATGATGACTACGCCATCAGTAGTACTAATTATAGTACCACCAGCAGTCGTCAACTATCGTCAACTCTCACGCCCTCTCACTGTCATAATCCCAATCGTTACAAGTGCGTTGATTGCGGCTCGCTATTTCCAACGCAGGCTGCGCTCAAGGAGCATATTAGCGAGGAGCATGATTTTATGGATATGCATTATAGTGCCAAAAAGTTCGACAACCCCGAACTGACTGATGAGACAGCTCCGGTTTCGGCTTCAGCTTCCGTTCAAGTGGCAACAATAAAAACGTCTTCAGGTGTTAAGAAGTCATCACAATTAAATCCATCTGGTTCTTCGACCATTGAACAAAACTATATATTCCTGTGCCCATCATGTGGCAAGGCCTACAAGACGCAGTTCGAGTGGCGTCGCCACATAAACGATGCTCACAATTTCGACAAACGTCAATACTTAAATATGCGCCAATTGGACAAGTATCGTTATCAGTGCAGTCAGTGTAAGGATATTGTGAGCAGCTCGAAGCTAAAGGGCCTACAGGATCACCACTTTCGCCATCTGCCCTATCGCCTGTATCTGAAGTGTCTCGTCTGCGGCACTTGCTACAATCACAAGCCCAACATCGCAGCTCATCTGCGTACGCGTCACAACATCTACGAACGCGATACACCATGGCGTGAATTACAGCCGAAGCCGCAGTACAACTATGTGATAATGAAAGACAAGGATAAAGAGAAAGAAAAGGAAGGTGGTCGAGGGATTTCCTCTAAGTCATCGTCGCCGACACCTGCCAGTAGCAGTAGCTGTAATGCAGGGCGTTCTCTAAAGCCGCAGCCAGGCGTATTGCCCACTCGACCCGCTGGACTGAATACGCTGGAGGATAGCATTTCATATCACAATGCTGTGGACTTGGATTTCATTACATACTATTGTCCTAAGTGCAATAAGAACTTTGACTCACATGCGTTCTGGCGCAAACACATTGTTGAACAGCACAATTACAACAGCCGTCAGGGCCTCAATTTTCGTCAGATCGATATTCATCATTATTTGTGCCTGGAATGCTACAAGCGTGTTACAGTCACCCACACCAAGGGTGCCATTGGTCAGTTGCAGTCGCATAAGTTCCGGCATCTGCCCTATCGATCCTTTAAGTGCCTGACCTGCAATGGTGAATTTGTGCGAAAGCAAATGTTCTTCAAACATCTGAATCGTGACACAAATCGCTGCGACAACAAGCCTTTGAGTGCCCAGGAGACGGACGATGATGGTGTAGAGCCTACCGAGAGTTTGGTTAGCGGCGGTGGCGATGATTGTTTAGTACCAGCTACTGCTAGTGCTTTAAGTGAAGTTGATCCCGCTGCTTATCGCCTGATATGTCCTCAATGCGGTGATAACTTTAAGACAACCAGCAAAGCACTATGGCGCGAACACATAAACATCTATCATGGCCTGGGCAAGCGAGAGCAGCTGCATATGCGCAAGATCGGCGAGGATCTCTATCGCTGCACAGACTGTGACGAGCAATTACAATCAAAACATTTGTGGATGCTGCAGGAACATCGCTTTCGCCATTTGCCCTATGCTCCCTACATTCGGTGCCAGGTGTGCGAAAAGCAGAAAGATGAACTGGGTCTTGGGACTGCTGCAGCTGGTCTGCACAGTATGATTGAGTTACAGCAACACATTCGCGAGAAGCACCCCGACTTGGCTGAGGGTGATGATCGAATAGAATCGCTGTTAGACGACGATGACGATGACGACCATCAACATACGAACGATGAGACGACAGGCAATGGACGATATATGCCGCTACCGCCGCATTTATTGGACGACGATGTGGATGATGTGGAATTTGAAGATCAGTATCTACTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDDVIDNYNHGNNADEFIGEEEEEEQEADIDEMDDDREVEQEREERRRKQKGNEPDDDAIFDFELEPIISIAEPELEPPVRRETVALAPPMATAGPPVRGVHRQSLPASFGSSLMPRGGSVVAATPPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCFICKREYKYRQDLMVHLRMVHCDEVVTMMRDGDTSAGRKTRVREPRTEQPRAASYDDDDVKHEEPVETEADAIVVGEEVEEKRKHSIPAATINGSSVSSAAEICEDYIHYMCPDCGNDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKSLRAHKFSHLSQPNWMRCKLCYKGYTEHHELVTHLLKQHHLETLMPDAEETDEPLCNISGGEVDGEDKTATGNDCEEELIAHWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLTKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKAAAGAVPSKVQTPRKQIVTVGNETYEIIYLDEEQSSPGNNNVNEENDFGEQMQADDDDYAISSTNYSTTSSRQLSSTLTPSHCHNPNRYKCVDCGSLFPTQAALKEHISEEHDFMDMHYSAKKFDNPELTDETAPVSASASVQVATIKTSSGVKKSSQLNPSGSSTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKRQYLNMRQLDKYRYQCSQCKDIVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWRELQPKPQYNYVIMKDKDKEKEKEGGRGISSKSSSPTPASSSSCNAGRSLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSAQETDDDGVEPTESLVSGGGDDCLVPATASALSEVDPAAYRLICPQCGDNFKTTSKALWREHINIYHGLGKREQLHMRKIGEDLYRCTDCDEQLQSKHLWMLQEHRFRHLPYAPYIRCQVCEKQKDELGLGTAAAGLHSMIELQQHIREKHPDLAEGDDRIESLLDDDDDDDHQHTNDETTGNGRYMPLPPHLLDDDVDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00556790;
90% Identity: iTF_00556790;
80% Identity: iTF_00556790;