Basic Information

Insect: Drosophila nasuta
Gene Symbol: -
Assembly: GCA_017165715.1
Location: Scf:4320-7684[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00014 0.0085 16.1 0.4 1 23 154 176 154 176 0.98

2 7 0.035 2.2 8.5 0.3 1 20 182 201 182 202 0.95

3 7 0.42 27 5.1 3.2 2 23 502 524 501 524 0.92

4 7 5.4e-06 0.00034 20.5 1.2 1 23 619 641 619 641 0.98

5 7 8.3e-07 5.3e-05 23.1 3.6 1 23 647 669 647 669 0.98

6 7 0.00012 0.0075 16.3 1.7 1 23 675 697 675 697 0.98

7 7 0.00023 0.015 15.4 0.1 1 21 703 723 703 724 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00014	0.0085	16.1	0.4	1	23	154	176	154	176	0.98
2	7	0.035	2.2	8.5	0.3	1	20	182	201	182	202	0.95
3	7	0.42	27	5.1	3.2	2	23	502	524	501	524	0.92
4	7	5.4e-06	0.00034	20.5	1.2	1	23	619	641	619	641	0.98
5	7	8.3e-07	5.3e-05	23.1	3.6	1	23	647	669	647	669	0.98
6	7	0.00012	0.0075	16.3	1.7	1	23	675	697	675	697	0.98
7	7	0.00023	0.015	15.4	0.1	1	21	703	723	703	724	0.96

Sequence Information

Coding Sequence: ATGCCGGAGGAAACAGTGATTGTCAAGGAGGAAATTGATATAGATGATACAAAAATAAAATTGGAGTTTAATGATGAAGAGCCGCCCCCGCTAAAATTGCTGCAAGGTGGCGGGCTATTAGAGATAATTGAAGAGCGGCCCAATATGATAACCGTGCCAGTTCACGACTACAAGTCCGAGGACGAACTCAAGTTCATTGCCAGTCTAGCCGCGATCGATGAGCAGCAGACGTTATTTATGACGCCAGCTTGCAAATCGAATGAAGCTCAAGTTTTTAGGGAATGCGAATGCAAAATATGCACGTTTATATGCAAAAATCATTTAGCATTGGGTTCGCATCACATCAACCATCAACTGAATCGACATTTCTGCAGAAATGGATGTGACTTTTGGTGTAATACGCTGGAAGAAATGTTGGACCATGAATATCGCCAACATCCGGTCGGGTTCACTTCCCAATTCAGCTGCAGAATATGTGAGAAGAAGTCTTCTACGGCCGTCAGCCTGTCAAGTCATATGGCCACACACTGCTATGAGCGGCGCTTTGTTTGTGCCATTTGTCGCTATCATTATGCGTCATTCGAGGAGTTGCAAGTTCATCGTCAATGCAGCAAAGCAGCGTGTGGTCGCATCGTCTATGCGGACAGGCAAGATAATATTGGGGAGCTGGTGTTAGTTAATAAACTAAATAATGCAGTGCCGTCGGAGCTTTGTAATGTGCAGATTAAAGAGGAGCCACTTAATGCGGCAGAAGAGCAACTTTTAAAAGTCAAAGATATCATTAAAACGGAACCAAAGGATGACCAAGTGGAGCAATTAAAAGCCGGCCAGGATGTCAGCTGGTCAAGTGCTAGTTTAATGGAAAAACTTCGGAGTAAATTGCGTTTGCCGGCGATAAAAAAAGCGGATGTGAAAGTTGAGACAGCTCACTCGTCTTCAAACACAAAATTTGATAAATTTAACCAAATATCTGAGCCCGTGGCCAAACGACCTAATATTCTAAAACCGGCCAGAAATAATCAACAAGCACCAAATGGCATTTCAACTGTTGCGCCCAACGTATTAAAAGTGCTACCCAACAATTGCATGCTCTTCAAATTACCGGCGAATACGAAAATAGTAAAGATTTCAAACACGACGCACAACAGTAGTACCATCTCTGAAGGGGGAAACAAGATAACCTCGTTGCCACTTACTCCACCAGCGATTACTCCCCCAGTGTCTTCCACTAATCGCAATGCGTATTTCAGTGATCTAAGTTCGTTTGAATCAACGCCCGAATCTCAGAAAATTATTGAAGACATCAAGAATCAAATACGGAATATAGAACAGACCTGTCCACTGCCAGGCAGTGTGCTTCATGTCCCAAAACACTTCATTAGCTGCATGACGCCGCAGCCAACGAACCAACCAGTGGAGGTGCTTAGTTTACCACTGACAAAGAACAGCAATGCAACTGTGCGAGAGATGCGTATTGCACATCCCACATATCGTTTTAGCTGGCAGTGTCCATATTGCGCCCTCTGTTATGAACTATATTCGGCATTTTGTAAACACTTGTCGTTTACCCACAATGTTCAGCAGTCGAACATGGACGATATAATTGTCCAGGTCAAGGCCAGCAAGATTTCGATTGCAGAAATTTCCAATCTGCCAAAGAAAGCAGAGCCGTCTCCATTAACTCCTGTTGCTGAAGCTGCTACAAGTGATCAGAAAGTTGTAACAGATGCAACTTACAAACTAGCGACAATTCCAGCTGATACAGCGTCCTCAACAACACCAGCGACTCCATTGTCACCTGCTTCAGGAGCTAGTCAACCAAAGCGAAATACATCTGTAATTCGGCCTGCACAGTATCAGTGTGAGGATTGCTCAAAATGCTTTACCACAGTGGGTGCTTTACGCATTCATAAGATGATACACACGGGAGAGCTGCCCCACAAATGTAATTACTGCGACAAACGCTTTCGCACACCTGGCCAAGTGCGTGTACATCAACGCAGACATACGGGCGAGAAGCCTTTCAAGTGCAAGATTTGTGCGCTGGCGTTCACACATCGTGAGACGCTCATCTCGCATCTGTCGCGTCACATTGGCATGAAGCGCTACAAGTGCTACGGTTGTGACAAGAACTTTGTTGTGGTTAGTGGATTGCGTGCACATCGTCGTCTACGGCCGGACACTTGTGGCAAGGTGAAGTTCACGGCGCGTGCACACGGACCGCGAGTTCGAGTCATAAGAGGTGAAGTTTTCTTTGAGTCCCACCCAGAACACAATGGTTATTTACGCAGCGAGGACCCTATAAATATTCTGTCTGAAAGAAACCATGTTGACATGGAACCAGATGTATCATCCAATGTTGTTAGTTAG
Protein Sequence: MPEETVIVKEEIDIDDTKIKLEFNDEEPPPLKLLQGGGLLEIIEERPNMITVPVHDYKSEDELKFIASLAAIDEQQTLFMTPACKSNEAQVFRECECKICTFICKNHLALGSHHINHQLNRHFCRNGCDFWCNTLEEMLDHEYRQHPVGFTSQFSCRICEKKSSTAVSLSSHMATHCYERRFVCAICRYHYASFEELQVHRQCSKAACGRIVYADRQDNIGELVLVNKLNNAVPSELCNVQIKEEPLNAAEEQLLKVKDIIKTEPKDDQVEQLKAGQDVSWSSASLMEKLRSKLRLPAIKKADVKVETAHSSSNTKFDKFNQISEPVAKRPNILKPARNNQQAPNGISTVAPNVLKVLPNNCMLFKLPANTKIVKISNTTHNSSTISEGGNKITSLPLTPPAITPPVSSTNRNAYFSDLSSFESTPESQKIIEDIKNQIRNIEQTCPLPGSVLHVPKHFISCMTPQPTNQPVEVLSLPLTKNSNATVREMRIAHPTYRFSWQCPYCALCYELYSAFCKHLSFTHNVQQSNMDDIIVQVKASKISIAEISNLPKKAEPSPLTPVAEAATSDQKVVTDATYKLATIPADTASSTTPATPLSPASGASQPKRNTSVIRPAQYQCEDCSKCFTTVGALRIHKMIHTGELPHKCNYCDKRFRTPGQVRVHQRRHTGEKPFKCKICALAFTHRETLISHLSRHIGMKRYKCYGCDKNFVVVSGLRAHRRLRPDTCGKVKFTARAHGPRVRVIRGEVFFESHPEHNGYLRSEDPINILSERNHVDMEPDVSSNVVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00562703;
90% Identity: iTF_00556749;
80% Identity: -