Basic Information

Insect: Drosophila nasuta
Gene Symbol: -
Assembly: GCA_017165715.1
Location: Scf:23645-26048[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.5e-05 0.00093 19.1 1.2 2 23 199 220 198 220 0.97

2 6 2.4e-06 0.00015 21.6 0.2 1 23 226 251 226 251 0.97

3 6 0.00095 0.06 13.5 0.1 1 23 258 283 258 283 0.90

4 6 1.5e-05 0.00097 19.1 1.9 1 20 292 311 292 314 0.92

5 6 0.00012 0.0076 16.3 3.7 1 23 322 345 322 345 0.97

6 6 0.00037 0.023 14.7 0.8 2 23 352 374 351 374 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.5e-05	0.00093	19.1	1.2	2	23	199	220	198	220	0.97
2	6	2.4e-06	0.00015	21.6	0.2	1	23	226	251	226	251	0.97
3	6	0.00095	0.06	13.5	0.1	1	23	258	283	258	283	0.90
4	6	1.5e-05	0.00097	19.1	1.9	1	20	292	311	292	314	0.92
5	6	0.00012	0.0076	16.3	3.7	1	23	322	345	322	345	0.97
6	6	0.00037	0.023	14.7	0.8	2	23	352	374	351	374	0.95

Sequence Information

Coding Sequence: ATGTTTAAATCAGAACGAAATTCAAGCGCGTGCCGCGCACTTGCAGATACAACTACAACTACAAACATAATTGAACCTACCTCTGCCTGTAATTCCTTGAGCAGAATGTCACTATGTCGTGCTTGCCTCGTGCTGCTTGGCAGCCAAGATGTGTCCTACGATTTGTGCCGTGAAAAAGATTTAGCTGTCAAGTTCTTGGGTTGCATGGGAAACCGAGCGAAAGGATTCCCTCAGGCTCTGCTGGACAGCAGCTTGAGCTGCAATGTTGTGCTGCAGTGCATCTGTGAGTGCTGTTATCAGTTAGTGCAAAAATTCCATGATTTCCAATGCATGTGCGAGGAATCCCAGCGAAACTTTGACAAAATTATGCTACAAGTGAATGCCAAGGATGTGGAGGAAATTCAGGAAAATACTATTGTTGAAACGTCGCTGGAGTCCCCTAAGAATGTGGAAGAAATTGCTCAGATTCAATCATCGCTGGTCATCGAAGAAATCGAAAAAGTCTATATCGTAGAAGATGAAACCGCCAAGGAAACGTTGGGTAAGGAGCGGATTCCCACTTCCCAACGAGCCCGTGGCGTACGCAACAAAACGGAATGTCACATCTGCGGACGTGGCTTCTACAAAATGTCCTTGTACGAGGCGCACATGCAGAAGCATCGCGGCGAACAGCCCTACAAGTGCACCTTTGATGAATGCGGAAAGACATATGCACGAGCCAATTTGCTGACTGCTCATCTCCGCGAGGTTCATCAGAACAGCACAAGGATTTATGCCTGCCTCGAACCCAATTGTAACAAGGTTTACACGGCGGCACGCAGTCTCAACTATCACATACGGCGGGGTCATCGCAAGGAGGAGTCGAGTGCTGCACACATTTGTGACAAGTGTGGAAAGTCGTATGGTCGCCGAGCTCACCTTACACGTCATCAATGGGTGCACAAGAGCAAGGGCGAGCGAAAGTTTGAGTGTAGCTATTGCACACAGCGTTTCTATACGAATCAGAATATGAAGGATCATCTAAAGCGACGTCATAGTCATAAGCCAGCTTTGCGTTGTCGTCGTTGTGGACGCATCTTTGAATCTCGCGCTGCGCTGAGCAATCACACTATGAAGAAGCATGCGAAACTGCGAAACAAAATGAAATGA
Protein Sequence: MFKSERNSSACRALADTTTTTNIIEPTSACNSLSRMSLCRACLVLLGSQDVSYDLCREKDLAVKFLGCMGNRAKGFPQALLDSSLSCNVVLQCICECCYQLVQKFHDFQCMCEESQRNFDKIMLQVNAKDVEEIQENTIVETSLESPKNVEEIAQIQSSLVIEEIEKVYIVEDETAKETLGKERIPTSQRARGVRNKTECHICGRGFYKMSLYEAHMQKHRGEQPYKCTFDECGKTYARANLLTAHLREVHQNSTRIYACLEPNCNKVYTAARSLNYHIRRGHRKEESSAAHICDKCGKSYGRRAHLTRHQWVHKSKGERKFECSYCTQRFYTNQNMKDHLKRRHSHKPALRCRRCGRIFESRAALSNHTMKKHAKLRNKMK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509319;
90% Identity: iTF_00472566;
80% Identity: iTF_00556716;