Basic Information

Insect: Drosophila nasuta
Gene Symbol: ken1
Assembly: GCA_017165715.1
Location: Scf:64582-67700[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.056 3.5 7.9 5.9 3 23 252 272 250 272 0.96

2 12 0.00075 0.047 13.8 0.5 1 23 278 303 278 303 0.94

3 12 0.0016 0.1 12.7 1.2 1 23 310 335 310 335 0.93

4 12 0.0013 0.085 13.0 4.1 1 23 345 367 345 367 0.96

5 12 0.0016 0.098 12.8 2.2 1 23 374 396 374 396 0.97

6 12 0.006 0.38 10.9 0.5 1 23 402 424 402 424 0.97

7 12 0.044 2.8 8.2 2.6 1 23 430 453 430 453 0.97

8 12 0.016 1 9.6 4.1 1 23 459 481 459 481 0.95

9 12 0.0077 0.49 10.6 2.3 2 23 488 509 487 509 0.96

10 12 0.00015 0.0097 15.9 0.8 1 23 606 629 606 629 0.95

11 12 0.00031 0.02 15.0 0.8 1 23 635 657 635 657 0.95

12 12 8.2e-06 0.00052 19.9 2.3 1 23 663 685 663 685 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.056	3.5	7.9	5.9	3	23	252	272	250	272	0.96
2	12	0.00075	0.047	13.8	0.5	1	23	278	303	278	303	0.94
3	12	0.0016	0.1	12.7	1.2	1	23	310	335	310	335	0.93
4	12	0.0013	0.085	13.0	4.1	1	23	345	367	345	367	0.96
5	12	0.0016	0.098	12.8	2.2	1	23	374	396	374	396	0.97
6	12	0.006	0.38	10.9	0.5	1	23	402	424	402	424	0.97
7	12	0.044	2.8	8.2	2.6	1	23	430	453	430	453	0.97
8	12	0.016	1	9.6	4.1	1	23	459	481	459	481	0.95
9	12	0.0077	0.49	10.6	2.3	2	23	488	509	487	509	0.96
10	12	0.00015	0.0097	15.9	0.8	1	23	606	629	606	629	0.95
11	12	0.00031	0.02	15.0	0.8	1	23	635	657	635	657	0.95
12	12	8.2e-06	0.00052	19.9	2.3	1	23	663	685	663	685	0.98

Sequence Information

Coding Sequence: ATGAATGAGGGGAGTGAATACTCCATACACTCGATATGCCGCGTATGCCTAAATCATCTGCGCAACGATGCCGTCTACGATCTATTCATGGTCCCAGGTCTGGCCAAAAAGTTGTGTGTGTGCACTTCGCTGTCCGTGGAACAACACGATGGATTCCCCAAAAACCTTTGCACCTCTTGCTACACAAAGCTCAACGATTTGCATGGCTTTCAAAAGATGTGCGTGGACTCAGTGCAAAAGTTTCAGGATATGGTAGCAAATAATTATTTCACTCCCGTCGGCATCTCGGATATTAATCAAATCGACAATGTTGATGTTCTCAATATTGCGCCACCCGAAAATGAAATGGAGGAGGATCGCATTAACTTTGATCCGCTATTGAATACGAAAATTGAAATAATCGAGAATGAAGACGATGTCTTCAAAATGCTTGAAGATGTGGACAAAGATGTCGAAGATGTAGAAAAGGACAAGGAATCATCGAGTGAAAGCGAAGCGGAAAATGAAGAAGAGGATGCAGACTTTGATGCGAATAGCAGCGAATCCGAGGACGCAGCGCCTCTATCACGATTGCGTGGCAACACCCGAGCCAGCAAGGCCAAGGGACGCAAGGCTGCCGCTTCTAACACCCGCGACGACGATGACGATGAATCCTCCAGCTCTGAGTCGTCGGATGACGACGATAGACCCAGCACGAAATCCAAACGCAAACGCATTCCAGCTGGCGAACGGGATCGACATAAGCTCATCGATTGTCACATCTGTCATCAGAAGTTCAAAAAGGCCATTCGATACGAGGAGCACATGAAGCACCATAACGATCTGTTGCCATTCCAGTGCACGGTAGAGTCGTGCAAGAAGGGCTTCACCACAGCCGGTGGCCTGCGCCTGCACATGGACCATGCGCACTCCGAGTTCTCCGAAGTACACGCCTGCACCTTTGAGGGATGCGACAAGACATTCCCCCGCTCCGTCTTGCTCACGTTCCACATGAAGAAGGTGCATAAGGTGGCCAAACCGGATGTGAAGCGACACGCGTGCACTGAATGCGAGAAGGTCTTCCGCTGTCCCACCGCACTCAAAAAGCACATGTACAAGCACACGGGTGAAGAGCTGCCCTTTGCATGCGAAATCTGCGGCAAACGATTCCACATACACAGCGTGCTCCGCGATCATCTGCTGCGTCACGCGGGTGTCAAGAATCATGTGTGTCCGTACTGTGGAGTGGGCAAGACAACGCGACAGGAGTGGAACAAGCACATCTTGACGCACACCCGCGAGAAACAGTTCCAGTGTCGACAATGTGATCATGCCTCGCACAACAAACAGGCCTTATCCAATCACGTCAAGGTGGTGCACATGAAAATCAAGAACTTTGCCTGTCAATACTGTGGCAAGACCTTTGGCAAGTCGCATGCATGCAAGATCCATGAAAGATTACATACTGGCGAAAACTGTTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTCTTCGAGAAACGTCTCACTAAGCACTTGCAGATCCACGAGAAACGAGATATTCCACCGCCAGCTACGGCGACGGCTGTTAAGCCGCCCGGCGAAGGTGATGGCCAAAACAATGTAAATCTCGGTCAGGGTGGAGAGCAGCAGAGTCATTTGGCAGAGCCAATGGACGTGAAACCCATACCGGTGATACCACCCAAGCCGAAGCCATCGCATCGTGTGGAACGCGTGGACATCTCTCAACTGGCGGGCACCTCGGTCAATCCCATATCATCGGTGTCGGTGCCTTCGTGGTCGCCGCAGGTGAACTTCACTAAGAAGGAGGGTCAGCACATTTGTCCGGGCTGTGGGCGTGGCTTCAATCATATTGGCAATATGAAGTTGCACTACAAGATCATACACGAGAAGGTCAAGGATTTCGCCTGTCGCTATTGTCCCAAACGCTTTGCCAAGGCTCAATACTTGCGCAATCATGAGTACATCCATACAGGCGAGAAACCATTCGAGTGTAAGATCTGTGGCAAACACTTCAGGCAGGAGCAGGTGCTTAAGACGCATCTAAAGGTGCACGATAAACCACCAAAGCCACCGAAGGAAAAGAAGCCGCCAAAGCCATCAGTTAGCAAGGCCAAGGGATTAAAGGTTGAGCTCAACAAAAAACAACCAAAGATTCATGAGGAATACCAGGATCCAGCGGCAGAGCGAGCAGCGGCCACCGCTGCGCTGCTCGCCCAGCAGATCGAGGAGAATGAGGCAAAGCGAAAGCAGGAGGAGGCGAATCGTAAAATACAGGAAGCCGCATGTGAGCAGCTGAATCGATTGCAAAAGCAAATACAAAGCGAAAAGGGCTCCTATGATAGCTATTACGGTCAGAAGGCTGAAGCCGAGGGCATTGACCCGGATGGTCTCAAATTAGATCACGTGTAA
Protein Sequence: MNEGSEYSIHSICRVCLNHLRNDAVYDLFMVPGLAKKLCVCTSLSVEQHDGFPKNLCTSCYTKLNDLHGFQKMCVDSVQKFQDMVANNYFTPVGISDINQIDNVDVLNIAPPENEMEEDRINFDPLLNTKIEIIENEDDVFKMLEDVDKDVEDVEKDKESSSESEAENEEEDADFDANSSESEDAAPLSRLRGNTRASKAKGRKAAASNTRDDDDDESSSSESSDDDDRPSTKSKRKRIPAGERDRHKLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCKKGFTTAGGLRLHMDHAHSEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKPDVKRHACTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKRDIPPPATATAVKPPGEGDGQNNVNLGQGGEQQSHLAEPMDVKPIPVIPPKPKPSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKPPKEKKPPKPSVSKAKGLKVELNKKQPKIHEEYQDPAAERAAATAALLAQQIEENEAKRKQEEANRKIQEAACEQLNRLQKQIQSEKGSYDSYYGQKAEAEGIDPDGLKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00608675;
80% Identity: iTF_00556698;