Dnas008921.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila nasuta
Gene Symbol
-
Assembly
GCA_017165715.1
Location
Scf:5474-9845[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00023 0.015 15.4 5.0 2 23 143 164 142 164 0.98
2 9 5.1e-07 3.2e-05 23.7 3.1 1 23 170 192 170 192 0.99
3 9 3.4e-07 2.1e-05 24.3 1.0 1 23 198 220 198 220 0.99
4 9 9.7e-06 0.00061 19.7 3.3 1 23 287 309 287 309 0.99
5 9 8.7e-07 5.5e-05 23.0 0.9 1 23 315 337 315 337 0.98
6 9 8e-07 5.1e-05 23.1 5.8 1 23 343 365 343 365 0.99
7 9 5.8e-06 0.00037 20.4 1.0 3 23 478 498 476 498 0.98
8 9 5.3e-06 0.00034 20.5 0.5 1 23 504 526 504 526 0.99
9 9 9.9e-08 6.2e-06 26.0 2.2 1 23 532 554 532 554 0.98

Sequence Information

Coding Sequence
ATGCATTTGAACCATGCGACGGCCGCAACAGCTGCGATGGCCAACTATCAGCACTATGCGCCCGCCCAGCTTGCCACGCACGGCGTGGGCGGTGGCGGAGGCGGTGGTGGTGCAGGCGGTGGCAGCGGCGGAGGTGGTGCAGGTGGCAGTGGCCTCAACCCTAACAGCCTGCAACAACCGACGACCATAGCAAGTCTGCAGCAGAGTCCGTTTGCGCTGCATCAACTGACCGCTGTCCAGGCCATACAACATCCCACCCATCAGGCGATGCTGCATCCACAGCATCCGCTGGTGCACCTGCTCGACATCTCCACAACGACCACCAATAGCGGGGGCAATCATACGCCCATCTCACCGATGAAACAAGAGGTGCAGAGTGTGGTCAGTGAGGATGAGTCGGTGGTGGATGATCCGCGCAAGAAAAAACAATGCCACGTGTGCAAGAACAAGTTCCGGCAATTGACCACGTTACGCAACCACATGAAAATCCACACCGATGAGCGTCCCTACAAGTGCAAACACTGTGACAAGGCGTTCCGGCAAATCTCGACGCTAACGAATCATGTGAAGATCCATACCGGCGAGAAACCGTTCACGTGCAACATATGCGCCAAGGACTTTCGACAGCAGAGCACGCTCATCAATCACATCAAAACGCATAAGGCGGCTGAGTCAAGCACGCCAACATCGCTACTCAACTATCAGCCGCCGTCGTCGTCGGGCAAGCACAGCCGCAAATCGCAGAATCAGATGCACAACGCCTATCAGCAGCAGCATCAACAGCAGCGTGTACAAATCTCAAAGACTCTTTACACCGGCACCTATAGCTCACCACAGGCGGATGAGCTGGTGAAACCGTATCAGTGCAGTGTGTGCAAACGGCGCTTCCCACAGTTGAGTACGCTGCATAATCACGAGCGGACGCACATCGATCCCAAGCCGTATAAATGCGAGACATGCGACAAGTCCTTTAGCCAACTGGCAACGTTGGCCAATCACAAAAAGATCCATACGGGCGATAAGCCATACACGTGTTCCTATTGCCACATGCAGTTCCGGCAGCAGAGCACGCTCACCAATCACATGAAGACGCACACACATCTCGCCAGCCAGCCAGCTACAGTCACAGCCACAGCGGATCACTCAGCGATGCCAGCGCCCCTTGTACCCGGCACACAGCAATTGACGAGCGGTCTGCTGCCCAATAACCTGCACAGCACAACACCCAACATCCTACAGCTGGACCATCATCCGCTGCTGCATTTCCTCGATGGCAACACAACGGTTAGCTCTGTGGTTGCCAGCAATGTGGCGGCAGCGGCGGCAGCGAATAACACCAAAATCGAACACTATCAGACGGCGCATAGTGGACGCATGAGTGTGGGCAACATCAATATGCTGAAGGGTGAAAATCCAGATCGGCCATTCGGCTGTAGTGTCTGCAGTCGATTCTTTTCGCAGCAGAGCACACTGGTGAATCACATCAAGACGCATACGGGTGAGAAGCCATACAAATGCAAGATCTGTGAGGTGAATTTCCGGCAAGTGGCCACGCTCAACAATCACATGAAGATCCACACCGGAGAGAAGCCCTACAACTGTTCCTACTGTCCCAAGCAGTTCAGGCAGAAGAGCACGTTACAAAACCATTTGAGGGTCCACACGTGTTAA
Protein Sequence
MHLNHATAATAAMANYQHYAPAQLATHGVGGGGGGGGAGGGSGGGGAGGSGLNPNSLQQPTTIASLQQSPFALHQLTAVQAIQHPTHQAMLHPQHPLVHLLDISTTTTNSGGNHTPISPMKQEVQSVVSEDESVVDDPRKKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDKAFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPPSSSGKHSRKSQNQMHNAYQQQHQQQRVQISKTLYTGTYSSPQADELVKPYQCSVCKRRFPQLSTLHNHERTHIDPKPYKCETCDKSFSQLATLANHKKIHTGDKPYTCSYCHMQFRQQSTLTNHMKTHTHLASQPATVTATADHSAMPAPLVPGTQQLTSGLLPNNLHSTTPNILQLDHHPLLHFLDGNTTVSSVVASNVAAAAAANNTKIEHYQTAHSGRMSVGNINMLKGENPDRPFGCSVCSRFFSQQSTLVNHIKTHTGEKPYKCKICEVNFRQVATLNNHMKIHTGEKPYNCSYCPKQFRQKSTLQNHLRVHTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00901644;
90% Identity
iTF_00559629;
80% Identity
iTF_00556641;