Basic Information

Insect: Drosophila murphyi
Gene Symbol: salm
Assembly: GCA_018904325.1
Location: JAEIFX010001243.1:19299511-19307504[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 2.2e-06 0.00015 21.9 1.7 1 23 367 389 367 389 0.98

2 8 3.1e-05 0.0022 18.2 3.5 1 23 395 417 395 417 0.98

3 8 2.2 1.5e+02 3.0 2.5 5 23 676 694 673 694 0.84

4 8 3.3e-08 2.2e-06 27.6 0.2 1 23 700 722 700 722 0.98

5 8 0.00098 0.068 13.5 0.9 1 23 732 754 732 754 0.98

6 8 0.049 3.4 8.2 0.1 2 23 972 994 972 994 0.96

7 8 1.1e-05 0.00073 19.7 5.0 1 23 1144 1166 1144 1166 0.96

8 8 8.5e-08 5.8e-06 26.3 0.7 1 23 1172 1194 1172 1194 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	2.2e-06	0.00015	21.9	1.7	1	23	367	389	367	389	0.98
2	8	3.1e-05	0.0022	18.2	3.5	1	23	395	417	395	417	0.98
3	8	2.2	1.5e+02	3.0	2.5	5	23	676	694	673	694	0.84
4	8	3.3e-08	2.2e-06	27.6	0.2	1	23	700	722	700	722	0.98
5	8	0.00098	0.068	13.5	0.9	1	23	732	754	732	754	0.98
6	8	0.049	3.4	8.2	0.1	2	23	972	994	972	994	0.96
7	8	1.1e-05	0.00073	19.7	5.0	1	23	1144	1166	1144	1166	0.96
8	8	8.5e-08	5.8e-06	26.3	0.7	1	23	1172	1194	1172	1194	0.98

Sequence Information

Coding Sequence: ATGTGTTCCATATTTCGCAATCGCATCAATTATCGGGGCACAGGAACACGCACAGGCACCTCCAATGGCAGTGGAGGAGGTGCAGGTGGCGGTGGAGGAGGCGGAGGCAGCAACAGCAGCAGCTCAGATCCAATTGGCGAACGGGAGAGTCTCCTGGCCAAGGAACTGAATGCGGACAGCAATAACAATGCGGCGGATGAGCCAATCGAGCCGGAAGTGGAGATGGAGCTGCAGCTGGAGAAGGAGAAGGAGAAGCAATCGGAGACATCAGTGCCCAGCTCCGATCAGCCAGAGAATAGCAATGAGGCATTGGATCTCTCGGTCATCTCGGGCAATCGGTTGCCCAACAGTGGGCATGTGGCACTAGAAGCTTTACAACATACCAAAGTGGCGGTGGCTCAGTTTGCGGCCACGGCGCTGGCGGCGGCATCCACAGATCCCAGTGATCTGGCCATGGTGCAGTCGACCATCTTTAATGTGCAGCGACAGCATCTGATGCAGCTGCAGCTCATCCAGCATCTGCAGAGTCAATTGAAGCGAGCGGGGGGCGTGGTCGCCGCCCTCAGCCGGCAGGGTCAAAACTATGCCGAGCAGGATGACGATGAAGCGGGAGAGGAGGCCGAAGACGTGGAGGAGTTGGAAGAGGAGCAGCAACTGTCGATGCCATCCAAAGAGCCGTCGCGAGTGAACGGTGAGCGAACCGAATTGGATCATGCAAGGCTGGAGGAGAGTTCAAAGACTGATGACGAGTGCAATAGGCTGGGCGAGAGACCAAGGCGTGCCTTGGCCAGGGAAAGATCGCGGGAGACGACGAAGACGGAGGCGGAGGCGGATGCTGAAGCCGAAGGCGAACACGAGCTGGCCGAGAGCGAGTACAAGCCACTGATGTGCGACATTAGCTCCAGTCTGGCGTCCAGCATCATCACCAATCATGATCCGCCGCCGGCGCCCAATGAGCCCAACTGCCTGGAGATGCTGCAGCGTCGCACCGAGGAGGTGCTGGACTCTGCATCGCAGAGTCTGCACGCCGCCCAGATGCAGGAGGAGTACTCGGAATATGCCAGCAAGGAGGCGCAGAGTCGCGGCGAGATCTTCAAGCATCGTTGCAAATATTGTGGCAAAATCTTCGGCAGCTATTCAGCCCTGCAAATCCATTTGCGTTCGCACACGGGCGAACGACCCTTCCACTGTAATGTTTGCGGCAGCAAGTTCACCACCAAGGGCAATCTCAAGGTGCACTATCAGCGGCACACGCAGATCTTTCCGCCCATGCTGATGCCACCCGTGGTCAACGGGGTCAGTGCACCCGAGCAGTTTGCTGCCATTCGGCTGCCGTTTGTGACACCACCAGCGGTGGCGGCAGCAGCAGCAGCACCACTGGCAGCACCACTACCACCCCCACCACCACCACCCCCGCCGCCAAGCAACGAACAGTCAGCGCTGGAACAGCTACAGGAGCCGACAGCTCTGGGACGACTGCAGCAGGCCGAGGATCTGAGCAAGCCACCAGCCACCAGAGAATTATCGCAGTCACCCGAGCAAGTCATGCAACCAACACCGTCAACCAAGTCGCTTATCGCGCCACCTGCGCTGGTGTCGCCCGAGAAACTGGACCAGGACAAGACAAAGGACAGTCCCAAGCCAACGACACCGCCAACGCCACCAGCTCCCTCGCCAACAACACCAACAACACCAACAACTCCAGCAGCAAGCAATCGTCGCAATGGCAGTGTCCGCAAGCGACAGACAAGCCAGGCGGGTAGTCCGCCTGGCGAGGAGCATCCTCATGCCGAGCATCACTCGCACCTGGTCAAGTTGGTGCGCCGCTCGTCGGCGAGCCGGGATGGGATGACAGCGATGCCTGGCGGTGGTTTGCCTGGCGAGTATTCGTTGGCGCAGATGGAGCGTATTATTGACAAGTCGTGGGAGGATCTCATTGAGATCGACAAGACGTCGGAGACATCGAAGCTGCAGCAGCTGGTCGATAATATTGAGAACAAGTTGACCGATCCCAATCAGTGCATCTTCTGCCAGAAGGTGATGTCCTGTCGCAGCTCCCTGCAGATGCACATACGCACCCATACCGGGGAGCGACCCTTTCGCTGCAAGATCTGCGGACGCGCCTTCGCCACCAAGGGCAACCTGAAGGCGCACATGAGCATCCACAAGATCAAGCCACCGATGCGCAGCCAGTTCAAGTGTCCGGTGTGCCATCAGAAGTTCTCCAACGGCATCATTCTGCAGCAGCACATACGCATCCATACCATGGACGATGGCAGCGCTGGTCATGCTCAGCTGCAGGGGCAGGGTGGCGATGTCGAACGCTTGGGCATCGAGGATCAGAACTCGAACAAATCGATGGGCACCTCAGACACGCTGGACTTCTCGACGACCGTCTCGGATCATTCGGGTCAGCGATCGGAGTCGTCGCAGGGTGGCGACTTCGATGAGTTCATGACCATGGACAGCACCGATGATTCGCGTGACAATTCCAGCGCACTGCTCGACAGGGAGAGGGAGCGAGATAGACGCCTGCCAGGGCACGATGATGAGCGCTCCCGGTCGGACGATGTGGAGGGCAGCGGACGTGAAAGTGCCAGCGGTGAGATGCCCGCCATGGATCTATCATCACCATCGCCATCGGCCACATCGCTGGCACGTCTCTTTGGTGTCGGTGGCGGCGGCAACAGCGGTGCAACGTGCTCAGGCGCTGGAGTTGCTGCTGCTGCTGCTGCTGCTGCTGCAGCCAATTCAGGCGGTTTGCCGATGTTGCATGGCATGCCGATGCCACCGAATCTGCTGCTGATGGCCGCGGCCAGGGAGGAGATGCATGCGCTGGGCCAGACGCATGCCAAGTTTCCGCTGTTGCCCTTCGGACCGCTCGGATTAATGGGACTGCAGCCGCCCCCAAATGTGTGCAATCTGTGCTTCAAGATGCTGCCCAGCCTGGCCGCCCTCGAGAGCCATCTGCAGAGCGAACATGCCAAAGAAGTGACGGCTCCTTCCGTTCGAGCCCACTGCAACGATGCGTTATCACCCTACGGTGCAAAGCTCACTCTCAATCCAAATCTGTTTGCCAAGAAGCCGAAGCCATCCTCAACGCTGGAGATGGCGCCTGCGGACTCAGTCACGCCATTGTCGGCACCCATTAAAGAGGAGCCCGAATCGGATCAGCAGCAGCAGCAGCAGCAGCTGCAGCTACTCGATGAGGGTGGCTGCGATAGTGGCACCAGTAGTGGTACTTCTGTGCCTGCTGCTGCTCCAGCTACTGCTGGCTATCAGCATGAGGCTGCCGCCGATGCGGAGCAATCCCTAATGAAGATGCAGTTGCATGCACATCGATTTCCAGCTGGTCCGCTGGACTTTCAGCAGGCCCTGATGTCGGCCGGCCCGCCCAGCTCTAGCTTGGATCCGCCGGTGAATAACAAGCACTTTTGTCACGTCTGTCGTCGCAATTTCAGTTCGAGTTCGGCACTCCAGATTCATATGCGCACCCACACCGGAGATAAGCCGTTTCAGTGCAATGTGTGTCAGAAGGCCTTCACCACGAAGGGTAACCTTAAGGTTCACATGGGCACGCATATGTGGACGAATCCGACATCGCGTCGAGGCCGTCGCATGTCCCTGGAGTTGCCGATGCGACCGGGACCTGGCCCGGGCCCAGGTGCCGCACATGGTGTACCAACGGCTGAGCAGGAGTTCATGCAGCGACGCCCAGAACTGTTCTTCCCATACTTGCCACCCTTCTTCAACGGAATGCCACCCAAGCCCGGCGAATTGAGTCCTGGCGCTTTTGCCAACATACCTCCACCGCATTTTGCAAATGGAGCCAAGTATCCATATCCACCGGGACTGCTCAGCTTTCCTGGCTTTCTGGGTGGTGCTGGCGGTCATCACCAGCATCCCTATGGCGGTGTGGAGCGAGGCAACAGCAAGTCACCCACATCGGAGCCGGCACAGAGTCCTGCTTCTCGTGAGGATGACTCGGGTCTCAGTAATAATATCTGGCATCCGCTGAGCAGCATTAAGATGGAGAGCAATCAAAATGAGAGCACTGGCAATCAGAGCGAGCAGGAACAGGAACAGGAACCGGAACCGGAACAAGAGCAGGATCAGGAGGATAATAAGAGTGTAGGCGTCGATGCGGATGGCGAGCCTGATCCGGATGCTGAGGATTCAGCTGAGAAGTAG
Protein Sequence: MCSIFRNRINYRGTGTRTGTSNGSGGGAGGGGGGGGSNSSSSDPIGERESLLAKELNADSNNNAADEPIEPEVEMELQLEKEKEKQSETSVPSSDQPENSNEALDLSVISGNRLPNSGHVALEALQHTKVAVAQFAATALAAASTDPSDLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAGGVVAALSRQGQNYAEQDDDEAGEEAEDVEELEEEQQLSMPSKEPSRVNGERTELDHARLEESSKTDDECNRLGERPRRALARERSRETTKTEAEADAEAEGEHELAESEYKPLMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFHCNVCGSKFTTKGNLKVHYQRHTQIFPPMLMPPVVNGVSAPEQFAAIRLPFVTPPAVAAAAAAPLAAPLPPPPPPPPPPSNEQSALEQLQEPTALGRLQQAEDLSKPPATRELSQSPEQVMQPTPSTKSLIAPPALVSPEKLDQDKTKDSPKPTTPPTPPAPSPTTPTTPTTPAASNRRNGSVRKRQTSQAGSPPGEEHPHAEHHSHLVKLVRRSSASRDGMTAMPGGGLPGEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSAGHAQLQGQGGDVERLGIEDQNSNKSMGTSDTLDFSTTVSDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSALLDRERERDRRLPGHDDERSRSDDVEGSGRESASGEMPAMDLSSPSPSATSLARLFGVGGGGNSGATCSGAGVAAAAAAAAAANSGGLPMLHGMPMPPNLLLMAAAREEMHALGQTHAKFPLLPFGPLGLMGLQPPPNVCNLCFKMLPSLAALESHLQSEHAKEVTAPSVRAHCNDALSPYGAKLTLNPNLFAKKPKPSSTLEMAPADSVTPLSAPIKEEPESDQQQQQQQLQLLDEGGCDSGTSSGTSVPAAAPATAGYQHEAAADAEQSLMKMQLHAHRFPAGPLDFQQALMSAGPPSSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPGPGPGAAHGVPTAEQEFMQRRPELFFPYLPPFFNGMPPKPGELSPGAFANIPPPHFANGAKYPYPPGLLSFPGFLGGAGGHHQHPYGGVERGNSKSPTSEPAQSPASREDDSGLSNNIWHPLSSIKMESNQNESTGNQSEQEQEQEPEPEQEQDQEDNKSVGVDADGEPDPDAEDSAEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00525326;
90% Identity: iTF_00514342;
80% Identity: -