Basic Information

Insect: Drosophila multiciliata
Gene Symbol: ZNF212
Assembly: GCA_037043605.1
Location: JBAMBF010000578.1:6489951-6492172[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 9.9 6.6e+02 1.0 1.1 1 7 41 47 41 51 0.86

2 11 6.1 4.1e+02 1.7 2.5 1 19 152 170 152 172 0.89

3 11 0.00068 0.045 14.1 3.7 2 23 216 237 215 237 0.97

4 11 0.00027 0.018 15.4 1.1 1 23 263 284 263 284 0.97

5 11 0.0004 0.027 14.9 0.9 2 23 291 312 290 312 0.96

6 11 7.5e-06 0.00051 20.3 0.4 1 23 339 361 339 361 0.97

7 11 8.2e-08 5.5e-06 26.5 0.9 1 23 367 389 367 389 0.99

8 11 0.0019 0.13 12.7 6.8 1 23 395 417 395 417 0.98

9 11 7e-06 0.00047 20.4 0.7 1 23 423 445 423 445 0.98

10 11 4e-06 0.00027 21.1 0.4 1 23 449 471 449 471 0.99

11 11 0.0016 0.11 13.0 0.1 3 23 495 516 493 516 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	9.9	6.6e+02	1.0	1.1	1	7	41	47	41	51	0.86
2	11	6.1	4.1e+02	1.7	2.5	1	19	152	170	152	172	0.89
3	11	0.00068	0.045	14.1	3.7	2	23	216	237	215	237	0.97
4	11	0.00027	0.018	15.4	1.1	1	23	263	284	263	284	0.97
5	11	0.0004	0.027	14.9	0.9	2	23	291	312	290	312	0.96
6	11	7.5e-06	0.00051	20.3	0.4	1	23	339	361	339	361	0.97
7	11	8.2e-08	5.5e-06	26.5	0.9	1	23	367	389	367	389	0.99
8	11	0.0019	0.13	12.7	6.8	1	23	395	417	395	417	0.98
9	11	7e-06	0.00047	20.4	0.7	1	23	423	445	423	445	0.98
10	11	4e-06	0.00027	21.1	0.4	1	23	449	471	449	471	0.99
11	11	0.0016	0.11	13.0	0.1	3	23	495	516	493	516	0.95

Sequence Information

Coding Sequence: ATGTCAGcACACAATGGAAAAAAGGCTGAgtcgacaacaacagcgcTGCAATCGCACGTGGATGCCAATAGCCAAAACAATATTGatcattttgtaattgataCGCGTGCGGATGAATTATACTACTGTGAGGATTGTGGCAATGACTACGATTGTATCGAAGCGTACAACAATGCACACAGTGGCCTTGACGGCTACGCAGGCGTATGTTCCAAAATTTCTCTTCATGCCGTCGAGATTAAAAATGAACCACAAGAAGAATATGATCAAGTGGATGTTGAATCCCTTATACTAGAGGATGACCTAATTGAGGAAGTCGACGATGCAAGTGAACCGCAGCTCTGGGAGGTGCTCGATGAGAATGAGGAACTGCTGGCAGCCGAAGTCGAGGACGAGGTGCAAGCTGAAACTGATGAGCCTGAGGCAGAGCAAATAACTACCAAGTCAGAGCGTTACTTTTGCTTCGATTGCCACAACATATTCATGACACGCGACAGTGCCGAGGAGCACAGCTGCCCCCTAGCAGAAGtaacaacaaccactacaAAGGGTGGCAAACAGAGCAATTCCAACAAGTTGGGCAAAACACAGACGCCAGTGCGACGCAAAGTGGCATCAGCCACAGCAGTGAGCAGCACCGTTACGGTTTGCCACATTTGCAAAACCCAATTCAGTTCGTCCAGAAGCCTCAAGTTTCATATGCGCATCCACAACAAGCGTGCCTCAAAATCCATACAGGATGCACTGCCCGTTGGCGCTCACCAGCAGTACAGCGAACTGGATCAATTCTATTGCGAAATCTGCGACAAGAGCTTCGAAAAAAACCTGTTAACGGTGCACAAACAAATGCATCAGAGCCATAAACAGGTTATGTGCGGCACTTGCAACCGGAAATTCGATAATCTAACCAACTATAAGTTGCATCTGAAGATCCACGAACGCAACGcggtaaacaaaaacagcagcaacaagcccAGTAAAGAGCCCGCCAATATTAACAAGGATAAGCCAGGATTCGCCTGTCAGTACTGTGGGCGGGTCTTTTCGCGTCCCTATGAGAAGGTGAAGCACGAGCGAGTGCACACTGGGGAGAAGCCCTACAGCTGTGAGGTGTGTGGAAAAACCTTTCGTGTCTCCTACTCCCTCACGCTACACCTgcgcacacatacaaacatacggCCGTATGTGTGCACCACGTGCAACAAGCGCTTCAAGACGCATACGGTTTACTCGCACCATTTGCGCATTCACAGCTCGGAGCGTCAGTATGTTTGTGATAGCTGCCCGAAGTCCTTTCGCACATCCGTGCAACTCTACGCGCACAAGAATAGTCACACAAAACCGTATCAGTGCACCGTCTGCAATCGTCCCTTTGCCTCACTCTACTCTGTCAAGGCACACATGTCCACCCACAAAACAAGCGATCCAAAGAATACTGGCGGTCAGGTCACCAAGAGCCAGCTAATGTGCAATAAATACTGGTGTGCTACCTGCGGTGCAGAATACACGCGGCCCTTTGCGCTTCGCCTGCACATGAAGGAAACCCATGGACATCAAGATGATGCGGATACACGCTTTGCAAAAATCCCACCAGcagatgatgacgatgagaTTATTGTGCCCGATACGGAGACGGCGGTTCTCATAGCAGCGGCTAAGGCCGATTCTGCATATCTATGCGATGCGCCAGATGAAGTGGATATTATGGATGCGGTGCCCAAATACGAGGAATGCATTGAAGTATCAGCAGATGCGTTCGATGTGGAAACGTTTCACAACGAGGAGATCGTCACCGATTGGCTAAAATAG
Protein Sequence: MSAHNGKKAESTTTALQSHVDANSQNNIDHFVIDTRADELYYCEDCGNDYDCIEAYNNAHSGLDGYAGVCSKISLHAVEIKNEPQEEYDQVDVESLILEDDLIEEVDDASEPQLWEVLDENEELLAAEVEDEVQAETDEPEAEQITTKSERYFCFDCHNIFMTRDSAEEHSCPLAEVTTTTTKGGKQSNSNKLGKTQTPVRRKVASATAVSSTVTVCHICKTQFSSSRSLKFHMRIHNKRASKSIQDALPVGAHQQYSELDQFYCEICDKSFEKNLLTVHKQMHQSHKQVMCGTCNRKFDNLTNYKLHLKIHERNAVNKNSSNKPSKEPANINKDKPGFACQYCGRVFSRPYEKVKHERVHTGEKPYSCEVCGKTFRVSYSLTLHLRTHTNIRPYVCTTCNKRFKTHTVYSHHLRIHSSERQYVCDSCPKSFRTSVQLYAHKNSHTKPYQCTVCNRPFASLYSVKAHMSTHKTSDPKNTGGQVTKSQLMCNKYWCATCGAEYTRPFALRLHMKETHGHQDDADTRFAKIPPADDDDEIIVPDTETAVLIAAAKADSAYLCDAPDEVDIMDAVPKYEECIEVSADAFDVETFHNEEIVTDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00500492;
90% Identity: iTF_00500492; iTF_00499037; iTF_00511441; iTF_00535484; iTF_00543901;
80% Identity: -