Dmul003499.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila multiciliata
Gene Symbol
-
Assembly
GCA_037043605.1
Location
JBAMBF010000288.1:18716-22075[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0016 0.1 13.0 0.5 2 23 143 165 142 165 0.90
2 12 7e-06 0.00047 20.4 0.4 2 23 179 201 179 201 0.94
3 12 0.35 24 5.6 8.8 2 23 470 491 470 491 0.97
4 12 1.2e-06 7.8e-05 22.8 2.8 1 23 497 520 497 520 0.96
5 12 0.00053 0.036 14.5 0.7 1 23 525 548 525 548 0.96
6 12 6e-05 0.0041 17.4 5.5 1 23 566 588 566 588 0.96
7 12 0.00012 0.0082 16.5 1.6 1 23 593 615 593 615 0.98
8 12 3.2e-05 0.0021 18.3 1.7 1 23 621 643 621 643 0.95
9 12 0.00011 0.0072 16.7 0.8 1 23 649 671 649 671 0.98
10 12 3.3e-07 2.2e-05 24.6 2.7 3 23 679 699 678 699 0.99
11 12 2.2e-08 1.5e-06 28.2 1.0 1 23 705 727 705 727 0.99
12 12 1.5 1e+02 3.6 5.2 1 19 732 750 732 755 0.88

Sequence Information

Coding Sequence
ATGCCTGACATTTATGATCAGTTCGATGCGGAGCGCGTCTGCCGTGTTTGTCTGCGCGAAGTGGGCGATTTTTACTTTATCTACGATGAAGCGCCCGTGGAGCAGGGCGCAAACATCGCTCAGATACTCAATGAATGCACACGGTATACGTGTGAGCGTTACGACAAGATGCCGCATAACATGTGTGACACCTGCATCAAGGCCGCCTGCCAGGCGTATCGCTTCAAGCGGGACGCTGAAAAGGCATATCGCTCGCTTGTTGACATATTGGGCCGCACACCCGTTAGCAGCCCGAACAGTACCGATATGTGCACCCAGACTGAACAGCTGCCCATGCTGCCGTGCGGCATCTGCAACGATAAGTTCTTAAGCATTATTGAAGTGCGCCTGCATAGGAATCGCCAGCACAAGAACATAGCGGAGCTCAAGTGCAAACTGTGCGACGAGAAATTCGAGCAATTGCGCCAGCTGCTTAACCATCTCGTAGAGCGACATGATCCCAAGTCGGCCACGTCGTTTTTGCGTCGCCGTCGCGAATGTCGCGACTGCCAACGCGTCTTCTCGCGACGCGATCTTTTGCTCCGTCATATGCAGGCTGTGCACAATGTGGTGGGCCGCGAGCGGACTCTGGCCGCGGAGCAGGAGCTGCAATCTGAAACGTGGCCGCCTGTCGACGAAGCAACCATGCACAGCGCCGACGAATTAATTTCGGCTGCCATCTTATTTAATGATCCAGCTGCGTGCTCCGATGACGAGAACGATAATACTAATAATGAAATGGGCTATCAACGCCATACGAATCCCATATCAAGCAACGACGACACTGAAGATGAAGAGATCCATGCGGAGGCTAAGCAATCTCTGTGGCTGCACATTAAGCCAGAGCCGGAAGCTGACCTCGATCCGTATCCCGAGTCATTTGTATCACCTGTAAATCGCGTGATGCAccgcaaaaaaacaaatatagaaCGTGCCACCCACATTGACGAGAATAAAGGATTCAACATCAAGAAAGTAGCGAGCAGTGATTTGGCAGCAGAGGTAAAAGAAGAGCCACTGGTCACGGGTAGCGAGCAAGTGTTACCGATTAAGCTGGAACGCCAGCGCACTGATAGCGTCAATGAGGATGGTGAGTATGAGATGGACGCCGGATCAGCCAACATTTATCACAGCGCCGATGAGGAGGACGGCGATGAAGAGTTTGTCAATGACGAAAGCGACATTGATGAATACGACGACGAAGATGACGACGAGCCGGGTGCCGAAAAAAAGCAGCGATCGGAGGACAAGTCCAAACAGACCCAAGCGAAAACTGTGCGCGATTATCTGCAGAAGCCGAATGCTGGCAAGCAGCGCCGTCGTCGCCGAAAAAAGCAGAGTGATTCTGCGGCACCCAACCCGGAGAATCGATGTGATGTCTGCATGCGCACATTTTCCCGCCACTGTCATTTGTTGCGCCACAAATTGTCACATTTGGAAAAGAAACCGCACAGCTGTCCGCATTGTCCCAAGGCGTTCGCGCGCAGCGATCATTTGAAAGCGCACGTGCAAAGTCTGCATGGCAACAAGGAGCACAAGTGTGTGCTGTGCGAGGCAGCATTTTCCCGCCTTGATGCCCTCGAGCGGCACAAGATGAGCAAGCACAATGGCGAGGGCCTGGACGCTAGCAGCGAGCTCAAACTGCAGATGAGCGAGCATACCTGCGAATACTGCTCTAAGCGATTCTCAAGCAAGACCTACCTGCGCAAGCACACGCTACTCCACACGGAATTCCTTTACGCCTGTAAGAGCTGCGACGAGACATTCAAGGAGCGCCAGCAGCTGCGCAGTCACGAGAAGACTCACACCGGTCAGCGCAATTTTCTCTGCTGCATTTGCGGCGATAGTTTTGCGCGCAACGATTATCTGCGCGTCCACATGCGTCGACATAATGGCGAAAAGCCATACAAGTGTCGTTTTTGCGTCAAGGCCTTTCCACGCGCCACGGATCTTAAAGTACATGAGCGCTATCACACCGGCACAAAGCCCAATCTGTGCAATACTTGCGGCAAGAGTTTCCACCGCGCATACAATCTGACCATACACATGCGCACCCATACTGGCGAACGTCCCTACAAGTGTGACCAGTGCCCAAAGAGCTTCAGCCAGAGCAACGACTTGAAGGCGCACATACGACGTCATACTGGTGAGCGCTACAAGTGCCCGCATTGCGATGCCTACTTTCTGCAGCTTTACCATATGCGCAATCATTGCCTCAGTGCCCATAACAAGCATATTGAGACTAAAACTGGTCGGCTACAGCGCACTGGTCTGTTGGACGAGTCCAGTCACACGCATCTTACCACTGTGGTCATGCCCGCAACACGTTCGCATTCATCAACGGGAGATCCGGCAGCGACAGTTGGCACACAATTGCCCGCATCGTCGACAGCGCCGGCGACGATTGCAACGACAATGATGCATTCCCCGGTGGCATATAACATAGCATCGCCAGCATCAGTGTCGGTGCCAGCGCCGGAAGCCGCCGGATTTGTAGGTGTAGCGAATAATGCAAGGGTGACGGCAACGGCCACGCCACCATTTTCGGCATATAATATACCTCCCGTGGTTATGGCGCAGTTAATGTACAATCATGGCAGCAACAGTCAGCAGAGCAATGTCAGCGGCAGCGAAACCGGAAAATAA
Protein Sequence
MPDIYDQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHNMCDTCIKAACQAYRFKRDAEKAYRSLVDILGRTPVSSPNSTDMCTQTEQLPMLPCGICNDKFLSIIEVRLHRNRQHKNIAELKCKLCDEKFEQLRQLLNHLVERHDPKSATSFLRRRRECRDCQRVFSRRDLLLRHMQAVHNVVGRERTLAAEQELQSETWPPVDEATMHSADELISAAILFNDPAACSDDENDNTNNEMGYQRHTNPISSNDDTEDEEIHAEAKQSLWLHIKPEPEADLDPYPESFVSPVNRVMHRKKTNIERATHIDENKGFNIKKVASSDLAAEVKEEPLVTGSEQVLPIKLERQRTDSVNEDGEYEMDAGSANIYHSADEEDGDEEFVNDESDIDEYDDEDDDEPGAEKKQRSEDKSKQTQAKTVRDYLQKPNAGKQRRRRRKKQSDSAAPNPENRCDVCMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCEAAFSRLDALERHKMSKHNGEGLDASSELKLQMSEHTCEYCSKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDESSHTHLTTVVMPATRSHSSTGDPAATVGTQLPASSTAPATIATTMMHSPVAYNIASPASVSVPAPEAAGFVGVANNARVTATATPPFSAYNIPPVVMAQLMYNHGSNSQQSNVSGSETGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00620004;
90% Identity
iTF_00511432;
80% Identity
-