Basic Information

Insect: Drosophila mulleri
Gene Symbol: L
Assembly: GCA_035047565.1
Location: JAWNPK010000060.1:12782021-12790771[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00079 19.9 2.9 1 23 168 190 168 190 0.98

2 17 0.35 27 5.6 6.2 1 23 196 218 196 218 0.97

3 17 1.7e-07 1.3e-05 25.5 3.2 1 23 224 246 224 246 0.99

4 17 1.2e-05 0.00096 19.6 0.4 1 23 252 274 252 274 0.99

5 17 0.014 1.1 10.0 0.2 2 23 355 379 354 379 0.93

6 17 0.00031 0.024 15.2 0.2 2 23 404 426 403 426 0.96

7 17 0.062 4.8 8.0 0.7 1 23 502 524 502 524 0.97

8 17 0.073 5.6 7.7 0.3 2 23 532 553 531 553 0.91

9 17 0.021 1.6 9.5 1.2 3 23 564 586 561 586 0.86

10 17 3.2 2.5e+02 2.6 1.0 2 23 622 644 621 644 0.95

11 17 0.0025 0.2 12.3 1.1 1 23 690 713 690 713 0.97

12 17 0.0064 0.5 11.1 1.6 2 23 895 917 894 917 0.96

13 17 0.11 8.8 7.1 0.1 1 23 923 945 923 945 0.92

14 17 0.25 20 6.0 0.6 2 23 953 974 952 974 0.96

15 17 0.31 24 5.8 1.3 1 23 1073 1095 1073 1095 0.94

16 17 0.0082 0.63 10.7 0.0 1 23 1105 1127 1105 1127 0.96

17 17 0.00022 0.017 15.7 1.2 1 23 1132 1154 1132 1154 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00079	19.9	2.9	1	23	168	190	168	190	0.98
2	17	0.35	27	5.6	6.2	1	23	196	218	196	218	0.97
3	17	1.7e-07	1.3e-05	25.5	3.2	1	23	224	246	224	246	0.99
4	17	1.2e-05	0.00096	19.6	0.4	1	23	252	274	252	274	0.99
5	17	0.014	1.1	10.0	0.2	2	23	355	379	354	379	0.93
6	17	0.00031	0.024	15.2	0.2	2	23	404	426	403	426	0.96
7	17	0.062	4.8	8.0	0.7	1	23	502	524	502	524	0.97
8	17	0.073	5.6	7.7	0.3	2	23	532	553	531	553	0.91
9	17	0.021	1.6	9.5	1.2	3	23	564	586	561	586	0.86
10	17	3.2	2.5e+02	2.6	1.0	2	23	622	644	621	644	0.95
11	17	0.0025	0.2	12.3	1.1	1	23	690	713	690	713	0.97
12	17	0.0064	0.5	11.1	1.6	2	23	895	917	894	917	0.96
13	17	0.11	8.8	7.1	0.1	1	23	923	945	923	945	0.92
14	17	0.25	20	6.0	0.6	2	23	953	974	952	974	0.96
15	17	0.31	24	5.8	1.3	1	23	1073	1095	1073	1095	0.94
16	17	0.0082	0.63	10.7	0.0	1	23	1105	1127	1105	1127	0.96
17	17	0.00022	0.017	15.7	1.2	1	23	1132	1154	1132	1154	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTAgagaatttaattgaaaagatTCAAGCGACCAAGGAGATAACTAATAACGATATGTACAGCACGCACACATCGTCGAGCTATTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAActcacagctgcagcagccgcagcagcagcagcagtcgcagcagcagcagcagtcacagaCGAGCTCGGAGGAGGCGGGCGAGGAGTCGGCCAAGGCGAATGGCGATGCGGCACAGCAatcggagctggagcaggagctgggcaAAGCGAAGCGACCGGCACAtttgcatcatcatcatcatcatcattatcatcatcagcaggcgCTGAAAATAGCGAACAAGCTGCGCAAAATCAATAAGGATGCAAAGCTGGCTGcaggacaaggacaaggacatGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGGCTCGGCTACCTCAAGCATCACGTGCAGAGTCATGCCGAGCATTTGCCTTTCAAGTGCGAGTACTGCGCAAAGCTGTTCAAGCACAAACGCTCGCGAGATCGCCACAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGTGATCATCTGAAGATCCACATGAAGACGCACGATATACAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCCGCCCTCACCTCGCACATGCAGAAGCACAAGAAGAACGCCGCGATTCTCGCAGCTGGCGGCAATCCCAATGCGCTCAATTACAGTCCACGCTCCACGGGCTCCGCCTCCATATCGAGCAATGGGAGCCTGCATAAGCGTCGCTATGCCTTGGCGCTGGCCTCCGACAGTAGTCCCAGCCGGCTGGAGTTTCCCAAGCGGCCGCGTGGCCAGCtgacggccacgcccacggccACAGCGATGGCCACGCCGACGCCCACGCcgctgctgcgctgcagctACTGCCCCAAGGCAACGGAGTTCAGCAGTCTCGAGCAGCTCAACGCGCATCTGCAGAGCACgcacgagcagcagccgcagcagccgcagcagcagcagtcgaagGAGTCGGACGGCCAGACGAACGGCTTCCAGTTGAGCTGCGAATATTGCACGATGAAGTTTGTGAATATCGCCGCGCTGTTCCAGCACATGAGAGTCACGCACTTGGATCGCCTGAGCAGTCCCAATTCCTATTACGAGCACTTCAATCGGCTCGGTTCGCCGCAGTCGAAGCTGAAGTCGGATCTGGCGGCAGCGGAGAAGCCCGAGCAGGAGCTGCCCACCGATctgagcagcaacaagcgacGTCCGCTGACCTCgcccacgcagcagcagcagcagcagcagcagccggcgccGGCGCCAGCACCACCGCCGCCTCCTGGCATCTTCTTCTGCAATCAGTGCAACGCCGGCCTGCCGGACTTTGAGAGCTTCCGCAATCATCTGAAGAGCCACATAGCCGAGGGCATGCAGCTGATCTGTCCGCACTGCGGCCTCAGTCTGCCCGAGCAGTGCGAGTACGAGCGCCATGTGGTCGCCCACTTCCTGATCAGCAGCTCCGAGTTCAAttgctgcagcgccagctgcgGCAAGTCCTATGCCAAGGCGGAGGAGCTGCATCAGCATCTGCTGGCCGAGCACGTCCAGACGATGCTGAAGTGCGTCCTGTGCTCGGAGCTCTGCGAGAATCGCATGTCCATGCAGCTGCACCTGGCCTGCGCCCATAGCCAGGAGTCGAagctgctgcgctgcagcgCCTGCCTGGAGCTCTTCCGCAACGATGGCGACTTCCATGTGCATGTGAAGACGCGCCATCAGCTGGGCAACCAGGGCGCTCTGCCCGGAGGCAATCCTCCAGCGCCGGCCAATCCGCTGCAGTGCATGTTCTGCCGCGCCGTCTGCTCCTCGGAGCTGGAGatgcatttccatttggcgGCGCATGCGCGACAATTCCGCTGCCCCAGCTGCCCGGAGACGTTCCACGTGGAGTTCCTGCTCGACAGGCATATGCAGAGCCAGCACGGCGGCATCAAGGACAAGGAGTcgcccgttcccgttcccgttccggGCGGCATGGGCAGCTTGTATGTGAatgcgctgctgccgccgttggcagcggctgctgctgccgctgccgcagcaaacaatgtgaacaacaacaacaacaacaacaacaataataatattgattacAATGTCGCCTTCAAGGGTCTCTTTGGCGGCAGCAATCCGCCGAGCAAGTTCTACAACAGCCCGCTCCAGGTGGACACCAAGCAGAGTCCGCATCCCGCTCTCATGTACGGCCTGAGCCAGCGCTACCTGATGGAAATGTACGCCGCCAAGGCCAATTCGCCAGCCAATGCCAGCGCCGCGGCAGAGCTGACCACGCCGCAGGCCGTGCCGTCCGCGGCAGCAGcgagcggcagcaacagcagcggcggcggcggcggcagcaacagcaacagctacagctgtgGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCCGAGCTCCACTCACATCGCAAGCTCGCCCACAATCTGAAGACGGGCGTCAGCCTGCGCTGCGCGTACTGCTCCGGGAACTACAAGAGCCGGgccgagctggagcagcacatGAAGAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTCCCCTCGCCCGCCATTCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAGTCCGGCAAGTGCGCCCACTGcggccagcagctggagcacgTGGCCGCCTTCCGCGCCCACCTGAGCGAGCATGGCAACGATGGCAATCTGCCCATGGCCTGCATCTGCTGCCGCCAGACGCTGCACTCGGAGTTCGAGCTGAGTCTGCATGCCAAATTCCACACCAAGTCGCCCAGTTGCAACAGCCTGCAGGAGCCGGTCTGCGCCCTCTGCCTGGAGCCGCTGCCGGGGGCAGGCGAAACGGCCAAGCTGTGCGACAAATGCTGCCGCAAGCACAATCTGAATGGCAAGCGCAAGGAGCAggcgcagccacagccgccgGGCACCGCTGCCCCAGCGGCCGGCGCAGCTGGCGCCTATCTGGAGCACCGCTGCAATCTGTGCAAGATGATCCTGCCGCATGCCCAGAAGCTGCAGGAGCATCTCGTCGAGCACACCTTCGCGGGCACCGAGCAGCGCGGCTACAATTGCTACATCTGCTCGGCTGTGTTCACGGCGCCCGCTGGCCTGCTCGCCCACATGGCTGAGCACGGCACGCGCCCGTACGACTGCAACCTGTGCCCGGAGAAGTTCTACTTTCGTGCCGAGCTGGAGCACCATCAGCGAGCGCACGAGCTGCGCGCTCAGCcggcagcaatggcagcagcagcagcagccgcagcagccgcagcagcagcaacagcagcaacacgtcCACCTAAGCAGGAGGCGCACAGCTCGACGGCCAGCTCCCCGGTGACGCTCAGTCCCAGCCACGTCAAGCAGGAGCTATACGAATCGGAGCCAGCGAATTCGCCCAACGCCGCCGAGCTGCCTgcgcagcaggaggaggaggagtacATTGAGGTGGAGCAAATGCCGCAGGAGACGCTGCGAGCTGGCGAACTGCTAAGCACCGAGcgttccagcagcagcgcctaa
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQLQQPQQQQQSQQQQQSQTSSEEAGEESAKANGDAAQQSELEQELGKAKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRPRGQLTATPTATAMATPTPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQPQQPQQQQSKESDGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNSYYEHFNRLGSPQSKLKSDLAAAEKPEQELPTDLSSNKRRPLTSPTQQQQQQQQPAPAPAPPPPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRNDGDFHVHVKTRHQLGNQGALPGGNPPAPANPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVPVPVPGGMGSLYVNALLPPLAAAAAAAAAANNVNNNNNNNNNNNIDYNVAFKGLFGGSNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPANASAAAELTTPQAVPSAAAASGSNSSGGGGGSNSNSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLSEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCNSLQEPVCALCLEPLPGAGETAKLCDKCCRKHNLNGKRKEQAQPQPPGTAAPAAGAAGAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPAGLLAHMAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRAQPAAMAAAAAAAAAAAAATAATRPPKQEAHSSTASSPVTLSPSHVKQELYESEPANSPNAAELPAQQEEEEYIEVEQMPQETLRAGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: iTF_00502755;
80% Identity: -