Basic Information

Insect: Drosophila mulleri
Gene Symbol: ham
Assembly: GCA_035047565.1
Location: JAWNPK010000012.1:399298-423396[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.56 43 4.9 0.0 2 21 372 391 371 394 0.87

2 9 0.037 2.8 8.7 2.3 1 23 401 424 401 424 0.91

3 9 1.8e-07 1.4e-05 25.4 1.7 1 23 430 453 430 453 0.96

4 9 3.3e-07 2.6e-05 24.5 1.5 1 23 459 481 459 481 0.97

5 9 8.5e-05 0.0066 17.0 3.8 1 23 487 509 487 509 0.97

6 9 0.0055 0.42 11.3 2.0 2 21 517 536 516 537 0.94

7 9 6.6e-09 5.1e-07 29.9 1.3 1 23 1030 1052 1030 1052 0.99

8 9 3.5e-07 2.7e-05 24.5 0.9 1 23 1058 1081 1058 1081 0.97

9 9 1.5e-05 0.0011 19.4 3.9 1 23 1087 1109 1087 1109 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.56	43	4.9	0.0	2	21	372	391	371	394	0.87
2	9	0.037	2.8	8.7	2.3	1	23	401	424	401	424	0.91
3	9	1.8e-07	1.4e-05	25.4	1.7	1	23	430	453	430	453	0.96
4	9	3.3e-07	2.6e-05	24.5	1.5	1	23	459	481	459	481	0.97
5	9	8.5e-05	0.0066	17.0	3.8	1	23	487	509	487	509	0.97
6	9	0.0055	0.42	11.3	2.0	2	21	517	536	516	537	0.94
7	9	6.6e-09	5.1e-07	29.9	1.3	1	23	1030	1052	1030	1052	0.99
8	9	3.5e-07	2.7e-05	24.5	0.9	1	23	1058	1081	1058	1081	0.97
9	9	1.5e-05	0.0011	19.4	3.9	1	23	1087	1109	1087	1109	0.98

Sequence Information

Coding Sequence: ATGTTATTCGAACGTTATATTATGCCAGGCTCTAACGGCGACGACTACGATCCGAGTGTCGTGCgccaccatcatcatcatcaccatcatttGGATCTCAGCAGTGGAGCGCCGCCCTTTGGTCCGCTGCCGCCGGCGCACTTGACCTCCAGCCAGGCTCGGCCCGAGGAGACGTTCGGCCGCCATCAGCCGCCAACGATATCTCCGCCTCCTGCAGCGCTGCTTCAGCaaccgtcgcagtcgcagtcgcagtcgctgcagcagcaaccatcgctgccgccgccgccgcatttatcattgcatttgcagcaacagcgactgcaacGCTCGCCGCCCGCTTCTGTCTCTGcctccggctctggctctggctcaggCTCCGGCTCTGGTTCCGGCAGCGGCACCAACATGGAGCACTTGTTCAGCGACAAGACGCAGGAGTTTCTAATGCAGATGGCGCGCCTGCGCGACCCCTTTTGTGATCTGGACATACGTGATAATGGCGTCTACGCCAAGACCGATTTGCCACGCGACTCCCGCTACGGACCCTTTCCCATGCACCTGTGCCAGCAGCCCAGCGATCGCCATCTGGCCTGGGAGGTAACTGCCGGACCGCTATTCCATGGCTGGCTGGAGCCCTCGGCGGATGTGGCCACATGGCTAAAAAAGATACGCAACGCCCAGATCGATGAGGCTGAAGAGGCTAATTTAAGGAATTTCATTGTCGATCGCTGTcTGTGGTACGAAACGAAACGGGATATTAGTGCTGGCGCTGAAATCGTGGTCGAGCCCCGCTCCCGCACGCCCTACGACATCAGCGACAGCCTACGGAAtggcagcatcagctgcagcagcagcggcagcagcagcgcggcagcagtggcagcaactgcagcagccgctgccgctgccgctgctgcagcagccgccatGGCCGCcgctagcaacaacaacaacagcatcaacaacaacaacaacaacaacaatagcgatGATCGCAGCGATCGTGATAACGgCTTTTACAGCGGCGACGAATTTGCGAAGGATAAGAAAAACATATCGATAAACAGTCAGGTCGATAACGATTTCACAGACGACGAGAACGGTTTCGATATACGCTGTGAGGTCTGTGATAATGTCTATACGGATTTAGAACGCCTGGACGATCATCTGGTGGGCGCGCATCACTTCAAACGTGGAGAATTCGCCTGTGAGCTCTGCTCCCAACATTTCTGCCATCGTCCGTTGCTGATCAAACACGGAGCGATCGCCCATAATAACATAAGGAAATATTCCTGCGAGAATTGTTCCAAGGTATTCTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCATCCGTGTCCGGAGTGCGGCAAAACATTCGCGACATCGTCCGGGCtgaagcagcaccagcacatCCACTCCTCGGTCAAGCCGTTCGCCTGCGAGGTCTGCTTCAAGGCCTACACGCAGTTCTCCAACCTCTGCCGGCACAAGCGCATGCACGCCGACTGCCGCATGCAGATCAAGTGCCAGAAGTGCAAGACGAGCTTCAGCACGGTCACCTCGCTCTCCAAGCACAAGAAGTTCTGCGACAGCTCCGACAGCTTTCGCAGCGGTCCACAGAGTCGCCTGgagcatcatcagcatcagcatcagcagcggcagcagcaccaccaccagcaccaccaacaccaccagcagtcgcagcagacGCAGGCGGGGCAACTGATTTTGCCACCTGGTGCGCATCAGCGactcgctgccgccgccgccgctgccgcagccagcagcaacagcagcgacacaTCTGCCATGGCCACGCCTCCGAATCACATGTTCACGATGCATCCCACGCACTCGTTCTTTCCGGGCTTTCCGCCGTACGCGCTGCCCAACTTCTTTACGAACTGCcggccgcagccgctgctgccgcccatGTTTCCCGGTCCGCATCTGGGCGAGATGGGGCGCGGCCTGGTGGCGCCGCTGGTCTCACCGAACGCGGccttccagcagcagctgcaggcggcGATGAGCCTGAAGTCGGAGTCGCCGCGCCTCAAGCGCGAGTCCAGCACGCCGGAGCGCAAGCATCCCATCAAGACCGAGCTGCAGCCCAGCgacgatgaggaggaggagcaggaggtgtCCAATGCCTATGAGCGGCTGGACTCGAGCAAGGAGTCGAGCAAGCCAACTGCGGAGTCAAAGCCGGAAGCTTCCGACCCACGGCCGGCACAGCACGACGATCAGGAGCAGGCCAAcgataatgacaatgacaatgacaatgacaatgataatgacaatgatattGACAACGATAGAAAATCCATTGACATAATGAGCACACCACCGCCCGCTGAAACGGAGGCGCAGCCGGAGCAGGATAAGAGCGGCGTGGATCTGCTGCCGCTGGATCTGTCCATCAGCCGCAAGCGCCGCAGCTCACTGTGCACGGCGAGCACGCCCGTGCCGCTGGCCATGTCGCTGTCCAGTCGCACGTCCACGCCCGCGCTGGAGATCGCGGAGGGCGCGGCCGGCCAGCCGCCCGTTAAGCTGATGAAGCACAGCTCCGGCGAATCGTCCACCTCGCATCAGTCCTTCAAGGGCAGCAGTCCCACGCCCAGTGTCAGCGCCTCGCCCGGACCcacgccctcgccctcgccgcCCATCAGCACGGGCGGCGAGCTGAGCAGCATGTCCGAGAGCGCGGCGTCCGCTGCCGCCGTGGGCGCTGCCtcggcggcggctgcggcggccTCGGTGATGGCCTGCCCGCGGCAGCTGCAtccccagctgctgctcgaggaGCTCTATCGCTCGCGCTTCAATACGCCACCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGCCACTCAAATCGCCGGCTGCTGgcatcagcagcggcagcagctcgcGTCATCTGCCGTTTCCGCCCGAGCACAATTTCCACGAGGCTCTGCGAGCCGCCGGCctggccgccgccgctgccaatgcctgcagcagcggcgccagcGTCGTCGCCGCCAACGGCGGCAAGCTCAAGGACCGCTACACCTGCAAGTTCTGCGGCAAGGTATTTCCGCGCTCCGCCAATCTCACCCGGCACCTGCGCACCCACACCGGCGAGCAGCCGTACACGTGCAAGTACTGCGATCGCGCCTTCAGCATCTCCTCGAATCTGCAGCGGCATGTGCGCAACATCCACAACAAGGAGCGTCCCTTCCGCTGTGAAATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCATCTGAAGAAGCATGAGGCGGATGCGGCTGGCTTCGAGTACAACGACTCGCCCAGCTCGAATGAGGCGGGCGATCGGGAGGAGGCCTGCTTCGATGACATTCGCTCCTTTATGAAGCGCGTCTATACGCCCACGAGTCTGGGCGGGGCGGATGGGGACACCGAGGAGTATGCGGGCAGCGATGATCAGTTGTCCGTGTCGACGCGTCACTCCGTTAGCTTTGACAaggagctgctggccaatggcaacaacaacaacaccaataacaacaacaacaacaacaacaacaataacaatagcagtagcagcagcagcaacaacaacaataacaacaacagcagcagcaatcagaCAGGTCTGGGCGAAACGATCGCCGTGAGCACTTAg
Protein Sequence: MLFERYIMPGSNGDDYDPSVVRHHHHHHHHLDLSSGAPPFGPLPPAHLTSSQARPEETFGRHQPPTISPPPAALLQQPSQSQSQSLQQQPSLPPPPHLSLHLQQQRLQRSPPASVSASGSGSGSGSGSGSGSGTNMEHLFSDKTQEFLMQMARLRDPFCDLDIRDNGVYAKTDLPRDSRYGPFPMHLCQQPSDRHLAWEVTAGPLFHGWLEPSADVATWLKKIRNAQIDEAEEANLRNFIVDRCLWYETKRDISAGAEIVVEPRSRTPYDISDSLRNGSISCSSSGSSSAAAVAATAAAAAAAAAAAAAMAAASNNNNSINNNNNNNNSDDRSDRDNGFYSGDEFAKDKKNISINSQVDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFACELCSQHFCHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCQKCKTSFSTVTSLSKHKKFCDSSDSFRSGPQSRLEHHQHQHQQRQQHHHQHHQHHQQSQQTQAGQLILPPGAHQRLAAAAAAAAASSNSSDTSAMATPPNHMFTMHPTHSFFPGFPPYALPNFFTNCRPQPLLPPMFPGPHLGEMGRGLVAPLVSPNAAFQQQLQAAMSLKSESPRLKRESSTPERKHPIKTELQPSDDEEEEQEVSNAYERLDSSKESSKPTAESKPEASDPRPAQHDDQEQANDNDNDNDNDNDNDNDIDNDRKSIDIMSTPPPAETEAQPEQDKSGVDLLPLDLSISRKRRSSLCTASTPVPLAMSLSSRTSTPALEIAEGAAGQPPVKLMKHSSGESSTSHQSFKGSSPTPSVSASPGPTPSPSPPISTGGELSSMSESAASAAAVGAASAAAAAASVMACPRQLHPQLLLEELYRSRFNTPPFHFLGQMGGRPGFEPLKSPAAGISSGSSSRHLPFPPEHNFHEALRAAGLAAAAANACSSGASVVAANGGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCEMCDRCFGQQTNLDRHLKKHEADAAGFEYNDSPSSNEAGDREEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRHSVSFDKELLANGNNNNTNNNNNNNNNNNNSSSSSSNNNNNNNSSSNQTGLGETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00568407;
90% Identity: iTF_00540519;
80% Identity: -