Basic Information

Insect: Drosophila montana
Gene Symbol: ken1
Assembly: GCA_003086615.1
Location: LUVX01052223.1:37137-39524[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00022 0.019 15.5 0.5 1 23 203 228 203 228 0.94

2 11 0.0014 0.12 12.9 1.2 1 23 235 260 235 260 0.93

3 11 0.00069 0.059 13.9 4.0 1 23 270 292 270 292 0.97

4 11 0.00096 0.083 13.4 2.1 1 23 299 321 299 321 0.97

5 11 0.0053 0.46 11.1 0.5 1 23 327 349 327 349 0.97

6 11 0.028 2.4 8.8 3.5 1 23 355 378 355 378 0.97

7 11 0.014 1.2 9.8 4.1 1 23 384 406 384 406 0.95

8 11 0.0068 0.59 10.8 2.3 2 23 413 434 412 434 0.96

9 11 0.00014 0.012 16.1 0.8 1 23 523 546 523 546 0.95

10 11 0.00027 0.024 15.2 0.8 1 23 552 574 552 574 0.95

11 11 7.3e-06 0.00063 20.1 2.3 1 23 580 602 580 602 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00022	0.019	15.5	0.5	1	23	203	228	203	228	0.94
2	11	0.0014	0.12	12.9	1.2	1	23	235	260	235	260	0.93
3	11	0.00069	0.059	13.9	4.0	1	23	270	292	270	292	0.97
4	11	0.00096	0.083	13.4	2.1	1	23	299	321	299	321	0.97
5	11	0.0053	0.46	11.1	0.5	1	23	327	349	327	349	0.97
6	11	0.028	2.4	8.8	3.5	1	23	355	378	355	378	0.97
7	11	0.014	1.2	9.8	4.1	1	23	384	406	384	406	0.95
8	11	0.0068	0.59	10.8	2.3	2	23	413	434	412	434	0.96
9	11	0.00014	0.012	16.1	0.8	1	23	523	546	523	546	0.95
10	11	0.00027	0.024	15.2	0.8	1	23	552	574	552	574	0.95
11	11	7.3e-06	0.00063	20.1	2.3	1	23	580	602	580	602	0.98

Sequence Information

Coding Sequence: ATGAATGAGGGGAGTGAATACTCCATACATTCGATATGTCGTGTTTGCTTGAACCACTTGCGAAACGACCCAGCCTACGACCTGTTTTTAGTCCCGGGTCTCGCTAAGAAACTTTGTGTGTGCACTTCGCTGTCTGTGGAACAGCACGATGGGTTCCCCAAAAACCTTTGCACCACTTGCTACACCCGGCTCAACGATTTACACGGATTTCAGAAACAGTGTGTGGACTCCGCCCAAAAGTTTCAAGAAATGGTGGCCAACAACTATTTCACGCCCGTTATTGCTGATATTAATCAAATTGACAATGTCGACATACTGCATGTACCGCCGCCGGATGGAGAAATGGACGAGGATCGTATCAATTTCGATCCGCTTCTGAATACTAAAATAGAGATAATCGAAAATGAGGAggatgtttttaaaatgttagaaGATGTCGACAAAGAAGTGGAGGAAGTAGAGAAAGAGAAGCAATCCTCCAGTGAAAGCGAACCCGacaatgacgatgatgataTTGACTTTGAAGCAAATAGCAGCGAATCCGACGACGCCATGCCCTTGTCTCGTTTACGAAAACACATGAAGCATCACAACGATCTGTTGCCATTCCAGTGCACTGTGGAGACCTGCAAGAAGGGTTTCACTACGGCTGGTGGTCTGCGACTTCATATGGATCACGCTCATTCGGAATTCTCTGAGGTACACGCCTGCACCTTTGAGGGATGTGACAAGACATTCCCACGATCTGTTTTGCTCACGTTCCATATGAAAAAGGTTCACAAAGTTGCTAAGGCCGACACACGGAATCATCCTTGCACGGAGTGTGAAAAAGTTTTCCGTTGCCCAACGGCGCtcaaaaaacatatgtataagcaCACGGGCGAGGAACTGCCTTATGCATGTGAAATTTGTGGCAAACGTTTCCACATACACAGCGTGCTAAGGGACCATCTATTGCGTCACGCCGGCGTGAAGAACCATGTTTGTCCCTATTGCGGTGTGGGCAAAACAACTCGACAGGAGTGGAACAAACACATATTGACGCATACCAGAGAAAAACAGTTCCAATGTCGTCAATGCGATCATTCATCCCACAACAAACAGGCACTCTCTAATCATGTTAAAGTGGTTCATATGAAGATTAAGAACTTTGCCTGTCAGTATTGCGGCAAAACGTTTGGAAAATCGCACGCATGCAAGATCCACGAGAGACTCCACACTGGCGAGAATTGTTGCGAGTGCAAAATCTGTGGTAAGATCTTCCTTTTCGAGAAGAGATTGACCAAGCATTTGCAGATTCACGAGAAACGCGAGGTACCACCCGCTGAAACCACTGTTAAATCTCAAGGCGATGGTGACGCACAAACTACCCAGAATTTGAACCAGGAATTGGCAGAGCCGGTGGACATAAAGCCCGTGCCAATAGTTCCTCCTAAGCCGAAGAATTCCCATAGAGTTGAACGTGTTGATATATCTCAATTGGCGGGAACCTCTGTTAATCCAATATCATCGGTTTCTGTACCATCTTGGTCGCCACAAGTCAACTTCACAAAGAAAGAAGGTCAGCACATTTGTCCGGGCTGCGGTCGTGGCTTTAACCACATTGGCAATATGAAACTTCACTACAAGATAATACACGAAAAGGTGAAGGACTTCGCCTGTCGCTATTGTCCCAAGCGCTTCGCCAAGGCGCAGTACCTGCGCaatcatgaatatatacatactggCGAAAAGCCTTTTGAATGCAAGATATGCGGCAAACATTTCCGTCAGGAGCAAGTGCTGAAGACACATTTGAAGGTGCACGACAAGCCGCCGAAACCCCCAAAAGCCAAGAAACCTCCAAAGCCTTCTGTTAGTAAAGCAAAGGGACTGAAGGTCGAACTCAACAAAAAGCAACCAAAGATTTTTGAGGAGTACCAGGATCCCGCTGCAGAACGTGCCGCAGCTACTGCTGCATTGCTAGCTCAACAGAGGGAGGAGAATGAGGCGAAGCGAAAGGCAGAAGAGGAAACTCGTAAGATTCAAGAGGCCGCTTGCGAGCAGCTCAATAGACTCCAAAGGCAAGTGCAGAATGAGAAGGGCTCCTATGATAGCTACTATGGACAAAAAGCTGAAGCTGACGGAACTAGCATTGATTCTCTTAAATTAGATCATGTATAA
Protein Sequence: MNEGSEYSIHSICRVCLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTTCYTRLNDLHGFQKQCVDSAQKFQEMVANNYFTPVIADINQIDNVDILHVPPPDGEMDEDRINFDPLLNTKIEIIENEEDVFKMLEDVDKEVEEVEKEKQSSSESEPDNDDDDIDFEANSSESDDAMPLSRLRKHMKHHNDLLPFQCTVETCKKGFTTAGGLRLHMDHAHSEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKADTRNHPCTECEKVFRCPTALKKHMYKHTGEELPYACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHSSHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKREVPPAETTVKSQGDGDAQTTQNLNQELAEPVDIKPVPIVPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKPPKAKKPPKPSVSKAKGLKVELNKKQPKIFEEYQDPAAERAAATAALLAQQREENEAKRKAEEETRKIQEAACEQLNRLQRQVQNEKGSYDSYYGQKAEADGTSIDSLKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00475414;
80% Identity: -