Dmon006467.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Drosophila montana
Gene Symbol
-
Assembly
GCA_003086615.1
Location
LUVX01005438.1:2984-10575[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.00011 0.0094 16.4 3.7 2 23 337 358 336 358 0.97
2 14 0.00068 0.059 13.9 1.1 1 23 364 386 364 386 0.99
3 14 0.00011 0.0092 16.4 4.8 1 23 392 414 392 414 0.98
4 14 1.1e-06 9.5e-05 22.7 5.0 1 23 420 442 420 442 0.99
5 14 6.8e-07 5.9e-05 23.4 2.6 1 23 503 525 503 525 0.99
6 14 0.0003 0.026 15.0 1.8 1 23 531 553 531 553 0.98
7 14 0.027 2.3 8.9 3.3 1 23 559 581 559 581 0.98
8 14 3.6e-05 0.0031 17.9 2.3 1 23 587 609 587 609 0.99
9 14 3.4e-06 0.0003 21.1 1.2 1 23 634 656 634 656 0.98
10 14 0.11 9.3 7.0 3.7 1 23 662 684 662 684 0.97
11 14 0.00011 0.0097 16.4 1.6 1 23 690 712 690 712 0.97
12 14 8.3e-06 0.00072 19.9 1.4 1 23 793 815 793 815 0.98
13 14 1.3e-07 1.1e-05 25.6 1.8 2 23 822 843 821 843 0.97
14 14 3.7e-05 0.0032 17.9 3.9 1 23 877 898 877 898 0.99

Sequence Information

Coding Sequence
ATGNNNNNNNNTGACGCTCTTCGCCGCGAATGGATCGCGAGTTGTGGCTTACCCCAGGATATTGATACGCGCAATGCGTATCTTTGCgatatacattttgaaaaattctgttttcacaaaaagaaaataagatcAGAAGCAGTGCCTACCCTACATTTGCCAGACCCTTCGCTGATGCCTATAGACATTCCTAAAGCACCGGATAATATGGACGAAACCCCGTTTTGTAGGGAAGACAACGCAATTGCCAAAATTCCgATTTGCAGGAGCTTCGTGGACACAACACCAGCTGCGGAAGTATGCCGTGCTTGCATGACCAGCTCAGTGGCACTCGTGGATATCTTCGCCGATCAGAGGCAACCCAGTCTGGCAGATATGCTAAACGACTGTGTCGCCTCCATCTCAGTCCAACGAAACGATGAGCTACCGCAGAAAATGTGCCTCTCGTGCATTTGTGATCTGCAAACGGCATTTGCATTCCAGCGCAGGTGTGAGGAAAGCCACCAAAAGTTACGCGacaatctaaataaaaataggatGGTATCCACAATAAACATGGAAATGCCAGAGGAAGACATAGAGATAGTTCGGCTCAAGATGGAAATAGACGAATTGTTGAGCACTGGGGATCAAATGGAATTCATGCCTGAAGATGAATGCAAAGCAGATACCCATGATATTTGTACACCCATAAGTATTTTCAGTTCTCGGGATGTTAATACTATAAGCGCCTTTAGCTCCAATCAAAGACAGTCTAGCCTTCTGATGGATAGCACAAATCTAAGCAACAGCGAGATTAATGTCCGGTCCGAGCTACTTGAAATAGAAAACTGGGAGCTGGCCGAGCAAGGTTATGAAATAGGCTGTACCGAAGTAGTAAAGGATACAGAAGATATCATTAAGGAGCAACAAACTGAACTTAGCTCAAAGAGCTACGAAGAATGCACCGTGGAGCACAATTCTCTTGCTGTTGACGAGCCTAGAGTAGATGCTAcaaaaaatcaacttaaatGCCCTCACTGTACTAAAGTCTTTCTGCATAAATCTTACCTCGATATTCACATTCGTACGCATACGGTCGAACGACCGTATCGGTGTCTTCACTGCTCCCAAGCATTTAGCATGTTCGCCGGTCTGCGCTTACACATCCTTACTCATGAAGGGAAAAATGCCTTTAAGTGTCCTCACTGCAGAAAATACTTTTCAGACAAGGCCAAACTCGATCAACACACGCGCTATCATATTGGGCACCAGGCTTACAAATGTCTACACTGTCCAAAAATCTTTACTCattcttcaaattttaaagacCACATTAGAATTCATCTCGCAAATAACAGTAGCGCCCACTCTGAACGGGTTGAAAAAGGAAACTGTGAGCTGGCCGAGCAAGATAATGAAATAGGCTGTACCGAAGAAGTAAAGGATAGTGAGGAAACCATTAAGGAGCAACAAACTGAAGTAAGCTCTAAGAGCTTCGAAGAATGCAGCAAGAAAAAGAATAGATACTCGTGCCCACAATGTCGAAAAGCTTTTATGTATAAATCTACCCTCAAACGTCACCTTCGTACGCATACGGGCGAACGGCCGTATAAGTGTCCACACTGCCCCAAAGCCTATCGACTTTTCACGGGCTTGCAATCACACGTCTTTACTCATGAAGGTAAAACTGCCTTCAAGTGTCCTCACTGCAGAAGATACTTTTTAGAGAAAGCCAAACTCGATGAGCACATGCGCTATCATATTGGGCGCCAGGCTTACAAATGTCCACAGTGTCCAAAAATCTGTACTGCTTTTGTATATCTCAAAAAGCACATTAGAACGCATACCGTAGAGAAAAGCGAAGAGCTTGATCCCATTGCTGTTAACAATCCTATAATGGAAGCTAAAAATGGCCAATTTATGTGCCCACATTGCCCCAAAACATATAAACTGTCCTGGAATCTGCGCATACACCTCCTTACTCATGAAGGGAAAACTGCCTTCAAGTGTCCTCACTgcagaaaatactttttagaGAAGGCCAAACTCGATGAACACACGCGCTATCACATTGGCCGCCGGGCTTTCAAATGTCCACACTGTCTAAAAATCTATACTAATCCATCATTTTTTAAAGACCACATTTTAGCTCATACCGCAGATAACAGTGAGCCAAATGTCCAATCTGAACGGGTTGAAATAGAAAACTCGGAGCTGGCCGAGCAAGATAATGAAATAGGCTGCAGTAAAGAAGTAAAGGATACAGAAGAtaacattaaagaaaaacaaactgaactAAGCTCAAAGAACTACGAAGAATGCACCgtggagagagagaaaatttGTAACCGTCTTGCTGTTAACGAGCCTAGAATAGATGATAAAAcgaaacaatttatatgcccACATTGCCCAAAAGCCTATATGAATGAGTCTTCCCTCAAAACTCACAGTCGTACGCATTCGGACGAACCACCACTTCAGTGTCCACACTGCCCCAAAACCTTTAGAAATTCCTCAGCTTTGCGCTCACACATCTTTACGCATGCAGGTGAGACTCCCTTAAAGTGTCTTTACTgcagaaaatactttttagaGAAAGCCAAGCACGAAGAACACACGCGCTATCACGTTGGGCCCCGGGCTTACAAGTGTCCACACTGTCCAAAAGTCTGTAATCTTAGAAATTTGACAAAGCACATTAAAATTCATgccaagaaaaatgttaaggAATAA
Protein Sequence
MXXXDALRREWIASCGLPQDIDTRNAYLCDIHFEKFCFHKKKIRSEAVPTLHLPDPSLMPIDIPKAPDNMDETPFCREDNAIAKIPICRSFVDTTPAAEVCRACMTSSVALVDIFADQRQPSLADMLNDCVASISVQRNDELPQKMCLSCICDLQTAFAFQRRCEESHQKLRDNLNKNRMVSTINMEMPEEDIEIVRLKMEIDELLSTGDQMEFMPEDECKADTHDICTPISIFSSRDVNTISAFSSNQRQSSLLMDSTNLSNSEINVRSELLEIENWELAEQGYEIGCTEVVKDTEDIIKEQQTELSSKSYEECTVEHNSLAVDEPRVDATKNQLKCPHCTKVFLHKSYLDIHIRTHTVERPYRCLHCSQAFSMFAGLRLHILTHEGKNAFKCPHCRKYFSDKAKLDQHTRYHIGHQAYKCLHCPKIFTHSSNFKDHIRIHLANNSSAHSERVEKGNCELAEQDNEIGCTEEVKDSEETIKEQQTEVSSKSFEECSKKKNRYSCPQCRKAFMYKSTLKRHLRTHTGERPYKCPHCPKAYRLFTGLQSHVFTHEGKTAFKCPHCRRYFLEKAKLDEHMRYHIGRQAYKCPQCPKICTAFVYLKKHIRTHTVEKSEELDPIAVNNPIMEAKNGQFMCPHCPKTYKLSWNLRIHLLTHEGKTAFKCPHCRKYFLEKAKLDEHTRYHIGRRAFKCPHCLKIYTNPSFFKDHILAHTADNSEPNVQSERVEIENSELAEQDNEIGCSKEVKDTEDNIKEKQTELSSKNYEECTVEREKICNRLAVNEPRIDDKTKQFICPHCPKAYMNESSLKTHSRTHSDEPPLQCPHCPKTFRNSSALRSHIFTHAGETPLKCLYCRKYFLEKAKHEEHTRYHVGPRAYKCPHCPKVCNLRNLTKHIKIHAKKNVKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-