Basic Information

Insect: Drosophila monieri
Gene Symbol: PRDM5
Assembly: GCA_035047585.1
Location: JAWNPJ010000031.1:269569-271525[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.34 27 5.6 0.6 3 23 266 287 265 287 0.92

2 10 5e-05 0.0039 17.7 0.1 6 23 296 313 296 313 0.99

3 10 5.6e-06 0.00045 20.6 0.4 1 23 319 342 319 342 0.98

4 10 9.7e-05 0.0077 16.7 0.4 1 23 351 373 351 373 0.97

5 10 0.014 1.1 10.0 5.5 1 23 380 403 380 403 0.97

6 10 6.6e-05 0.0052 17.3 1.9 1 23 409 431 409 431 0.96

7 10 0.28 22 5.8 0.9 2 23 440 461 439 461 0.96

8 10 2.1e-05 0.0017 18.8 2.2 2 23 467 489 466 489 0.95

9 10 2e-07 1.5e-05 25.2 0.7 2 23 496 517 495 517 0.97

10 10 0.00017 0.013 16.0 4.4 1 23 523 546 523 546 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.34	27	5.6	0.6	3	23	266	287	265	287	0.92
2	10	5e-05	0.0039	17.7	0.1	6	23	296	313	296	313	0.99
3	10	5.6e-06	0.00045	20.6	0.4	1	23	319	342	319	342	0.98
4	10	9.7e-05	0.0077	16.7	0.4	1	23	351	373	351	373	0.97
5	10	0.014	1.1	10.0	5.5	1	23	380	403	380	403	0.97
6	10	6.6e-05	0.0052	17.3	1.9	1	23	409	431	409	431	0.96
7	10	0.28	22	5.8	0.9	2	23	440	461	439	461	0.96
8	10	2.1e-05	0.0017	18.8	2.2	2	23	467	489	466	489	0.95
9	10	2e-07	1.5e-05	25.2	0.7	2	23	496	517	495	517	0.97
10	10	0.00017	0.013	16.0	4.4	1	23	523	546	523	546	0.96

Sequence Information

Coding Sequence: ATGATCTGCCGCCTCTGCCTGCGCAGCCTGAGTCCCGGAACAGCAGTTTTTCTCTTTGAAACGAACGAGACTCTGGCGGAGACGCGCCTGGTGAAGATTATCGCTAAGTTTCTTCAAATGGAAATCGTTCCGGACGATGGAATCTCGACCAGCGTGTGCACAGAGTGCTGCGAGCATCTCGAGGACTTTCATAGCTTCTGGCAGCTGGTGGAGCAGAAACAGAGCACCATCATGAACGAGGAGTTCATATCCGTGGACGTGGACTGCGGCGACCTAAAGTGGACAGGAGGCGTGGACGTGAATCTAGACGAGCTGGCTCTGCCTGCGGGGGACGTCGATGAGAAGCCTCTGGACATGCACAACCTCAGTTTGCTGGGCAGCGTACTCGATGTGAATGTCGACAGTGTGGAGGTAACCGCCGCCAAGAAGCAGTcccaggaggaggagaagccaCTGGTGCAAAAAAGTGATAGTAGCGACTCGGAGCCCGAGCCCACATCGTTTCCCGCCGAAGATTCATCATCCGATgacgAGCCACTGGTCCGGCTGAAGGCAAAAATGAAGCCGAAGCGCAAGGTACGGTCCAAGGTCAAGCGCACAGTTTCACTGCAGCAGGAGCTTAAGGATCTACTAACCGATGGCAGCAAGCGGCGCACGAAGCGGTCTTCTACCGAGCCCACCGAGATGCAGGAGACCGAGCTACAGGCGGTGCTCGAACGCAAACCCAAGGGCTGTTCCCGCGCCCAGCTGGCCAAGCGCTACGAGGAGGCCATTGCCAGTTACATGAGCGCCAATTGCGATCTGTGCGAATTCAGCGCCCCGTACCTGTCCGACCTGAAACACCATTTCCAGGAGGTGCACCAGCGCGAATACTACATCAAGTGCTGTGGCAAGGTCTTCGCACGAGCGTCCAAGCTAATGGATCACATCCGGAAGCATGTCAACCCCAAGCTCTTCACATGCACCATCTGCCAGAAATCGCTGAACTCACAGGACTACCTTGCCACCCACATGGAGACGGTCCACAACAAGGTCGCCCAGGTTCTGAAGTTCCCCTGCGCCAAGTGCGATCGCACTTTCAGCAGCGAGCGCCGGCTGGCCAATCACTTGGCCAAGCACGACTCTGACCAGTTGGAACACACCTGCGAAATCTGCTGCAAGAGCTTTGCCAATGTACACCGTCTGCGGCGACACATTCAATCTATCCACGAAGATCTGCATCGTCACGTGTGCGACATCTGTGGAAAGAAGTTTAAGTTCAAGCCCTCCTTTGATCGCCACCTGCTGGAGCACCAGGGCGTGGTGGCGCCTGCGATGGAGTGCTCGGTTTGCGGCGTATGGCTGAAGAACGAGCACAGCCTGCGTCTGCATCGATTCACCCACGACAGCACGGACACAGTGTGTCCGCACTGCGGCAAGACCTGCTCATCCCGCACAGCACTGCGTGGCCACATCAAGTACGCCCACAAGCTGACAACGAACCTGCAGTGCACCTACTGCGAGAAGACGTTCAAACAGCAGCGCAACCTAGAGGAGCACATGGCCATCCACACGGGCCTCCAGCTTTACAACTGCCCGCACTGTCCCAAGGAGTGTCGATCCCGGTCCAACATGTACGTCCACATCAAGCAGCGGCACGCAGACGAGTGGCTGCGCGCCAAGATGGCCCGCTCTCACAATCCGCAATTCAAGCCAGGACCGGAGGCAACTGCGGTGCCATCCTGA
Protein Sequence: MICRLCLRSLSPGTAVFLFETNETLAETRLVKIIAKFLQMEIVPDDGISTSVCTECCEHLEDFHSFWQLVEQKQSTIMNEEFISVDVDCGDLKWTGGVDVNLDELALPAGDVDEKPLDMHNLSLLGSVLDVNVDSVEVTAAKKQSQEEEKPLVQKSDSSDSEPEPTSFPAEDSSSDDEPLVRLKAKMKPKRKVRSKVKRTVSLQQELKDLLTDGSKRRTKRSSTEPTEMQETELQAVLERKPKGCSRAQLAKRYEEAIASYMSANCDLCEFSAPYLSDLKHHFQEVHQREYYIKCCGKVFARASKLMDHIRKHVNPKLFTCTICQKSLNSQDYLATHMETVHNKVAQVLKFPCAKCDRTFSSERRLANHLAKHDSDQLEHTCEICCKSFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFDRHLLEHQGVVAPAMECSVCGVWLKNEHSLRLHRFTHDSTDTVCPHCGKTCSSRTALRGHIKYAHKLTTNLQCTYCEKTFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLRAKMARSHNPQFKPGPEATAVPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492388;
90% Identity: iTF_00481701;
80% Identity: -