Basic Information

Insect: Drosophila monieri
Gene Symbol: ZFY
Assembly: GCA_035047585.1
Location: JAWNPJ010000061.1:1864306-1866240[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.9e-05 0.0031 18.0 1.4 1 23 194 217 194 217 0.98

2 14 8.8e-05 0.007 16.9 3.5 1 23 226 249 226 249 0.95

3 14 2.4e-07 1.9e-05 25.0 2.2 1 23 266 288 266 288 0.99

4 14 2.5e-06 0.0002 21.7 2.5 1 23 294 317 294 317 0.98

5 14 0.0001 0.0081 16.7 1.1 1 23 328 350 328 350 0.95

6 14 0.0059 0.47 11.1 0.6 1 20 356 375 356 377 0.94

7 14 0.00048 0.038 14.5 2.1 1 23 389 411 389 411 0.99

8 14 4.5e-06 0.00035 20.9 2.6 2 23 418 439 418 439 0.97

9 14 0.00012 0.0094 16.5 0.3 1 23 453 475 453 475 0.97

10 14 6.2e-05 0.0049 17.4 4.2 1 23 481 503 481 503 0.99

11 14 0.00011 0.009 16.5 1.3 1 23 509 532 509 532 0.90

12 14 2.8e-05 0.0022 18.4 1.9 1 23 538 560 538 560 0.99

13 14 0.00097 0.077 13.6 0.2 1 23 566 588 566 588 0.98

14 14 7.1e-06 0.00056 20.3 0.1 2 21 601 620 600 621 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.9e-05	0.0031	18.0	1.4	1	23	194	217	194	217	0.98
2	14	8.8e-05	0.007	16.9	3.5	1	23	226	249	226	249	0.95
3	14	2.4e-07	1.9e-05	25.0	2.2	1	23	266	288	266	288	0.99
4	14	2.5e-06	0.0002	21.7	2.5	1	23	294	317	294	317	0.98
5	14	0.0001	0.0081	16.7	1.1	1	23	328	350	328	350	0.95
6	14	0.0059	0.47	11.1	0.6	1	20	356	375	356	377	0.94
7	14	0.00048	0.038	14.5	2.1	1	23	389	411	389	411	0.99
8	14	4.5e-06	0.00035	20.9	2.6	2	23	418	439	418	439	0.97
9	14	0.00012	0.0094	16.5	0.3	1	23	453	475	453	475	0.97
10	14	6.2e-05	0.0049	17.4	4.2	1	23	481	503	481	503	0.99
11	14	0.00011	0.009	16.5	1.3	1	23	509	532	509	532	0.90
12	14	2.8e-05	0.0022	18.4	1.9	1	23	538	560	538	560	0.99
13	14	0.00097	0.077	13.6	0.2	1	23	566	588	566	588	0.98
14	14	7.1e-06	0.00056	20.3	0.1	2	21	601	620	600	621	0.94

Sequence Information

Coding Sequence: ATGGACTTTGTTGCCAAGTCGGAAAATCTTCTGCAGCTGCCGGACAACGGGAGACAGGAGATGGCCCATCCGGCAATCCTGAGGCGCTACGTCCCGGTAAGGGGCGAGACGACCGAAGAGGAGTACATTCTGGAGGAGGCGTTCATACGAGTGGCGGCCGAAAACGAGGCGCTGGTCAAAAAACTTAAGAGGCGGAGAAGTGAAGAGGCGGCGCCGGGATTCGAGGACAGCGGCCTGGGAAACCCATTCCGGGTGAAAAACGAGCCCATTGATGAAGAGTACCCGCCGTACAACAATTCAGAGCTAGAACAGCCTCCCAGTCCAAGTGAGAGCATCCACTTCGATACCATCATTAAGGAAGAGGACCCTGATTTCACGGTTAACGTCGAAGAACACTGCGACTATGCGGCGTCTGAGAGTGAGGAAAGTTTGCTGGAAAGAGTAGGTTATAGAGGGAGTAGCTACCACGATAACGAAGAGTATGGCAACGAAGAGGATGTCAACGAAGAGGACGACGAGGATGAGGACGAAGTAGAATCTCAAAATTATTCTGAGCACTCCAACGAAGACTCGAGTTCTTACAGATGCCCCCGTTGTCCTAAGAGCTTTAAGTTGGCCAAGAACCGTAACAAGCATCGGCTAACCGCCCACCCACCCAACACCGGAAAGCGCACCTACCAGTGCAAGCACTGCAAAAAGGTCTACGCGCAAAGGGCAGGCTACAAAAGGCACCTGACCAACAATCACAATGATGAGGACTCGGAACTAGAATATGACTCTGACGAGGAGAAGATTTACAAATGCGCTCGTTGCCCAAAGAGTTTCAAATATTTGTCAAACCTACGGAAACACGCCCGGACGCACACCAGCGGGCTTCCCTACAAATGCAAACGCTGTAATATGAGCTTCTCCCAGAAGGCACGTTACCAAAGACACATGCGTGTTCCCCACAAGGCGGACGGAACACCAATGGATCGCCCATTCAATTGCTCAAAGTGTGGGAAGGGGTTTATAACAGAAAAAGACTTGGATCGGCATCGCTTTCTCCACGCCGAAGGTCATCCCTATAAGTGCGATCTATGCGAGGCGACCTTCAGGAACGAAAAACGCTATCAAAATCACTTGACGATGATCAGTCGTGATGGAAAGTGCCCGTCGGTTACTTTTCAATGCACTCACTGTCTGGTGATTTATAAATCTAAGAGGGCTCTTGCTCGCCACGCCCGGAGACATGACCCCAACTGGTGGCCCACATGCCCCATATGccagaaaatttttaagaacGCCACCACCCTCCGGAGACATCACAAAGTTCACGTTTTTCCCAGAGAACCGccaaagaaaaaggaaatttCGCACTATTGCAGCGTTTGTTCGAAAGGCTTCCCCGCAGCTCGGTACCTGATCATCCACATGCGAGTGCATACGGGCGAAAGACCATTCCAATGTATGCATTGTACGAAGAATTACAAGCAGAGAGGACAACTCTCCGTGCACCTGAAAACCCACACCGGAGAGAAAACTTACAATTGTTTACAGTGTACTATGACGTTCACATACAAGTCCTCGCTCAAGCGCCATGTTGGTAACGTACACAGTGAGGGGCGGCCGTTCAAATGTCCGGAGTGCGATAAAACCTTTGCTTCCATGTATAGGATGCGCGAGCACAAGAAAACCCACACCACAGAGCGCCCTTTCAAGTGCCCCGAATGCCCAATGGCCTTTATATCGGAACATGGCCAGAAGGTCCATAGACTCATTCACTTAAAAGAACCTGTTGATGCTCCATCCAAACGAGTCAAATGCCCTCTGTGTCCCAAGACCTTTGCAAGGAATCAAGGGCTGAAGGCCCACATGTTGAAACAAGGGTTGAAGGACCATGAGGAGCCTAACtcttccaaaataaaattggaaGAGGACGCAACCGAATCTTGA
Protein Sequence: MDFVAKSENLLQLPDNGRQEMAHPAILRRYVPVRGETTEEEYILEEAFIRVAAENEALVKKLKRRRSEEAAPGFEDSGLGNPFRVKNEPIDEEYPPYNNSELEQPPSPSESIHFDTIIKEEDPDFTVNVEEHCDYAASESEESLLERVGYRGSSYHDNEEYGNEEDVNEEDDEDEDEVESQNYSEHSNEDSSSYRCPRCPKSFKLAKNRNKHRLTAHPPNTGKRTYQCKHCKKVYAQRAGYKRHLTNNHNDEDSELEYDSDEEKIYKCARCPKSFKYLSNLRKHARTHTSGLPYKCKRCNMSFSQKARYQRHMRVPHKADGTPMDRPFNCSKCGKGFITEKDLDRHRFLHAEGHPYKCDLCEATFRNEKRYQNHLTMISRDGKCPSVTFQCTHCLVIYKSKRALARHARRHDPNWWPTCPICQKIFKNATTLRRHHKVHVFPREPPKKKEISHYCSVCSKGFPAARYLIIHMRVHTGERPFQCMHCTKNYKQRGQLSVHLKTHTGEKTYNCLQCTMTFTYKSSLKRHVGNVHSEGRPFKCPECDKTFASMYRMREHKKTHTTERPFKCPECPMAFISEHGQKVHRLIHLKEPVDAPSKRVKCPLCPKTFARNQGLKAHMLKQGLKDHEEPNSSKIKLEEDATES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -