Dmoj000623.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mojavensis
Gene Symbol
EGR3
Assembly
GCA_018153725.1
Location
JAECYD010000019.1:4086365-4145570[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 3e-07 2.3e-05 24.6 0.2 1 23 1014 1038 1014 1038 0.97
2 3 5.3e-06 0.00041 20.7 4.0 1 23 1044 1066 1044 1066 0.99
3 3 0.00014 0.011 16.1 0.3 1 21 1072 1092 1072 1093 0.94

Sequence Information

Coding Sequence
ATGTTGCTGACAATGAGGCGACAGAATGAAGTGATAAGCAGCCAGCAGCATTCCACGACGACAGCCCCAGCCACGCCCTCGCCGCCCACGGCCAGTCAATCAGCCACGCCCGGCTTGAGCCTGGTGCCCACTAGTCCAGCCGCGACGCAGGACTCCCTGAACACGCCCACCACGCCCCTCAGCCGCAATCCGCTGCAGTCCTTTGCTGCACCACCCGCACCGCCGCCCATTGCAGTGCCCGCCTCGGCGCCCGCCTTCGGCTACTACAATAGCACCACCAGCTCAGCTGCGACCAGCTCGCCCGCGCCCACTTACCTGCACCACGCGCCGACTCCTGCTGGCAAGGACTCCGCCGGCCATTCCGTGGAGCTTGACGAGTACGTGGATATTCTGCAAGTGCAACAGTTGCTGCTTGACTCTTCCGCGGCTGCGGCAGCGGCTGCCCTCCCGCCCCCCGACAACCAGCAGCAGCAGCAGCAGCAATTGCACCAGCAGGAGCAGCAGCTCGCTAAGCCGCGACCGCGCATCAATTTGCAGAAGGCATCGGAATATGCCGCTCAATTAGCGCAGGCTGAGACATCCTCGCCTGCCTCGCGCCGCGTTCTCCTCGACTATCCGAGCCCCTACTTATACGGCAATCACTATCACCACACGCCGCCAAGCGAGGACCTCGTGGCCCTTTGGTTTGGTAGCAATGGAACAGGCGGCGTAGCCCCTGGAACTCCATCAGCGGCCATGATCATGGAAGGGCTTGAAACCCTGGTGGCGCCCACGCATCACGCATTCCTGCTCACCGAAACGGCCGCCGCGGCCCACTTCAATGTGCTGAGCTTTGACACGTGCCTGTTCAAGACCAGCACGGCGCAGAGCGGCAGCCCCTCGGCTGCCAGTTACCTGGGCGCCGCGCAGTTCGGCGCGGCCAGCAGCTCCTCCGCGGCTGCCAGCAGCAGCGGTGGCCAGACTCTGCTGCACTACACGACAGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCGGTGCTGCGCGCACGCAATCAAACAGCCACGCCCACACAGGGCGGCAGTCCAGGCAGCGTGGCAGCCCAGCCAAGTGCAGGCAGCGCAGCAGCCGCCAGCAGCGGCCGCAGCTCCGCCTCGCACCTCAGCCTGCTGAACACCAGCCAGCAGAGTCCCGTCACAGCCAGCGAGCACGGCGTGGCCGTGGAGGCCAAACAGCTCATCGAGGCTCTGCCCGGCGATCTCAATACACCGGTGACCACGTCGAGCGACATTCCGTCGTTCTTTGGCCCATCCACAGTGGTTGAACCACCGCCAATAACCGGCTCCATTGCATCCGAGGATCTGTCGCTGGAGCCGCAGGTGGTGTCCGCTGCCAGCCCCGTGTTGTCCTCCTGCAGCCCGCTGAAGGAGGAGCGCAGCACGCCGCCCGCCCTCTCCATTGTCAAGGAAGAATCAAGTAATAATAGTTGTAACATGTACCCACTACANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTACGACGATGGACGCGCTGCCGTGACTGCGGCTCAGCACGCCGAGCTGTTGGGCCTCAGCATGGACTGCACGCCCCTGAAGCAGGCCTCGATCTACACCGGCGGCACCGTGTCGACCGCCAACTTTGCGGGCCTCGCCGAGCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCTAGCTCGAGCAACGCAGCGCTCGGCGTGCTCATACCCAAGCAGGAGACCTACACGGACATGCAGCCCAGCTCGAACGGCACAGGCTACTCCAGCGCCTCGGCTGCTGCGGCTGCCGCAGCCGCTGCTGCCGTCCAGCTGGCCGAGTACAGTCCGTCCACCAGCAAGGGCCACGAGATACTGTCGCAGGTCTACCAGCAGAGCAGTGTGCCGCTGAAGCTGGTGCCCGTCAAGCCCCGCAAGTACCCCAACCGGCCCAGCAAGACGCCCGTGCACGAGCGGCCGTACGCGTGCCCCGTGGAGAACTGCGACAGGCGCTTCTCGCGCTCGGACGAGCTCACCCGCCACATCCGCATACACACGGGCCAGAAGCCATTCCAGTGCCGCATCTGCATGCGCAGCTTCAGCCGCAGCGACCACCTGACCACCCACATCCGCACCCACACCGGCGAGAAGCCCTTCAGCTGCGACATCTGCGGCCGCAAGTTCGCCCGCTCCGACGAGAAGAAGCGCCACGCCAAGGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGCTTCCAGTGCGACCAGCATGTAG
Protein Sequence
MLLTMRRQNEVISSQQHSTTTAPATPSPPTASQSATPGLSLVPTSPAATQDSLNTPTTPLSRNPLQSFAAPPAPPPIAVPASAPAFGYYNSTTSSAATSSPAPTYLHHAPTPAGKDSAGHSVELDEYVDILQVQQLLLDSSAAAAAAALPPPDNQQQQQQQLHQQEQQLAKPRPRINLQKASEYAAQLAQAETSSPASRRVLLDYPSPYLYGNHYHHTPPSEDLVALWFGSNGTGGVAPGTPSAAMIMEGLETLVAPTHHAFLLTETAAAAHFNVLSFDTCLFKTSTAQSGSPSAASYLGAAQFGAASSSSAAASSSGGQTLLHYTTAXXXXXXXXXXXXXXXXXXXXXSVLRARNQTATPTQGGSPGSVAAQPSAGSAAAASSGRSSASHLSLLNTSQQSPVTASEHGVAVEAKQLIEALPGDLNTPVTTSSDIPSFFGPSTVVEPPPITGSIASEDLSLEPQVVSAASPVLSSCSPLKEERSTPPALSIVKEESSNNSCNMYPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYDDGRAAVTAAQHAELLGLSMDCTPLKQASIYTGGTVSTANFAGLAELXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASSSNAALGVLIPKQETYTDMQPSSNGTGYSSASAAAAAAAAAAVQLAEYSPSTSKGHEILSQVYQQSSVPLKLVPVKPRKYPNRPSKTPVHERPYACPVENCDRRFSRSDELTRHIRIHTGQKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFSCDICGRKFARSDEKKRHAKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASSATSM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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