Basic Information

Insect: Drosophila mojavensis
Gene Symbol: Znf48_1
Assembly: GCA_018153725.1
Location: JAECYD010000036.1:12606241-12607671[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 9.6e-06 0.00075 19.8 1.0 2 23 12 33 12 33 0.97

2 11 0.023 1.8 9.2 4.1 1 23 39 62 39 62 0.95

3 11 7.9e-07 6.1e-05 23.3 1.1 1 23 150 172 150 172 0.99

4 11 0.0075 0.58 10.7 3.2 1 23 178 201 178 201 0.96

5 11 0.42 33 5.2 3.8 3 23 209 230 207 230 0.86

6 11 9.6e-05 0.0075 16.7 2.3 1 21 235 255 235 256 0.95

7 11 0.033 2.6 8.7 6.0 1 23 279 301 279 301 0.97

8 11 1.3e-06 0.0001 22.6 1.6 1 23 313 335 313 335 0.97

9 11 3.7e-05 0.0028 18.0 4.2 1 23 341 363 341 363 0.97

10 11 3.4e-06 0.00027 21.3 0.4 3 23 372 392 370 392 0.96

11 11 6.3e-06 0.00049 20.4 0.9 1 22 398 419 398 422 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	9.6e-06	0.00075	19.8	1.0	2	23	12	33	12	33	0.97
2	11	0.023	1.8	9.2	4.1	1	23	39	62	39	62	0.95
3	11	7.9e-07	6.1e-05	23.3	1.1	1	23	150	172	150	172	0.99
4	11	0.0075	0.58	10.7	3.2	1	23	178	201	178	201	0.96
5	11	0.42	33	5.2	3.8	3	23	209	230	207	230	0.86
6	11	9.6e-05	0.0075	16.7	2.3	1	21	235	255	235	256	0.95
7	11	0.033	2.6	8.7	6.0	1	23	279	301	279	301	0.97
8	11	1.3e-06	0.0001	22.6	1.6	1	23	313	335	313	335	0.97
9	11	3.7e-05	0.0028	18.0	4.2	1	23	341	363	341	363	0.97
10	11	3.4e-06	0.00027	21.3	0.4	3	23	372	392	370	392	0.96
11	11	6.3e-06	0.00049	20.4	0.9	1	22	398	419	398	422	0.92

Sequence Information

Coding Sequence: ATGAAAAAGATTGAAAAATCGAAAAGTTTAAACACCTGTGATACATGCGGCAAGTGCTTTATGAAGCCAGCTTTGCTCCGTCGGCATCTAGCTGTGCACAGTGGCGACAAGGCATTTCCATGCGAAAGCTGCTGCAGTCGCTTCTCTCAAAAAAGTTCACTGCTACGTCACAAACGCATCAAGCATGATGTGGCAAAGGAGTGCGACGACTCCGACGTAGCGCAACATGCACTGGCTGCGCTGAAGCTGTTGCAAGGCAGCCATACGCCTACAGATAATGCGATTGCTACCCAAATGAAATCATTAGGTTCGTTAGGCTCACTGCGCACTCTGGAAGAGAAAGCATCTTGTAATGTAGTAGAACTGAGGGACAAGCTCAATCCAGCTGGTGAAGTCCATATTCTCATCACACAGCGCATAGTGCGACAGAAGCCCAATCGATGCTACTATGTCTGTGAATATTGCGCTAAGGAATTCAGCAAGAGTTACGATTTGATAAGGCATCGTCGCTCGCACACCAAAGAGACGCCCTATCCGTGCAATCAGTGCTGCAAGCGGTTCGCCACTGAGAGCAAGCTCAACGAGCATAACAAACGCCTGCATGCTACTGTGAAAAAGCATGCATGCATCCAGTGTACTTCCAGTTTCAGCAGCAAGAGTAGGCTACACAAACATTTGGCTGAGAAACATCCTCATATGGTGCATAGCTGCACGCACTGTAGTCGAACCTTCCAATCGAAATCTGCCTATGAGGCACACATGAAACTAGAAGCAGATCCGATCAGAGGAAAACTCATCGAACTTTTGCCACAGCCAGTGCTGTCGCAGCGCAGCTACAAGTGCATCTACTGCGAAAAGCAATTTACACGCAAATTCAACTGCCGCACACACATGCTGCTGCATCTGCGGCGTTTGGTGGACCCAAAACAGATGAAACATAGTTGCCTGCAATGTGGCAAACAGTTCAAGCGACCCAACGACTTGGCCCGTCACTTGCTAACTCATTCGAAGCTTAAGCTGCACATATGCCACGTATGTCAAAGACGATTCACCCTAAAGTCCACATTGGCCAGACACCTGGAAACGCATCAGCCACAGCGGAGCAACGTTAATTGTCAAGTGTGCGGCAAGAGCTATGCCTCCAAGACATCACTGCAGCTACATCTGCGGTTGCACACCGGCGAACGACCCTTCAAATGTGAAATTTGCGGCGAAACCTTTCGTACATCAGGACACAGATTGGAGCATATGCGAGCCGAACGGCACAAGAATGCATCGTCCAATGCACTAATTCTTTGA
Protein Sequence: MKKIEKSKSLNTCDTCGKCFMKPALLRRHLAVHSGDKAFPCESCCSRFSQKSSLLRHKRIKHDVAKECDDSDVAQHALAALKLLQGSHTPTDNAIATQMKSLGSLGSLRTLEEKASCNVVELRDKLNPAGEVHILITQRIVRQKPNRCYYVCEYCAKEFSKSYDLIRHRRSHTKETPYPCNQCCKRFATESKLNEHNKRLHATVKKHACIQCTSSFSSKSRLHKHLAEKHPHMVHSCTHCSRTFQSKSAYEAHMKLEADPIRGKLIELLPQPVLSQRSYKCIYCEKQFTRKFNCRTHMLLHLRRLVDPKQMKHSCLQCGKQFKRPNDLARHLLTHSKLKLHICHVCQRRFTLKSTLARHLETHQPQRSNVNCQVCGKSYASKTSLQLHLRLHTGERPFKCEICGETFRTSGHRLEHMRAERHKNASSNALIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516414;
90% Identity: iTF_00551728;
80% Identity: -