Basic Information

Insect: Drosophila mojavensis
Gene Symbol: prg
Assembly: GCA_018153725.1
Location: JAECYD010000036.1:15579120-15580979[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.17 13 6.5 0.8 1 23 227 250 227 250 0.90

2 9 0.00036 0.028 14.9 0.1 1 23 256 279 256 279 0.96

3 9 8.6e-07 6.7e-05 23.1 1.4 1 23 285 307 285 307 0.98

4 9 9.7e-08 7.5e-06 26.1 4.3 1 23 313 335 313 335 0.98

5 9 1.3e-05 0.00098 19.5 0.8 1 23 341 363 341 363 0.98

6 9 0.0001 0.0081 16.6 1.1 1 23 369 391 369 391 0.98

7 9 2.9e-05 0.0023 18.3 0.5 1 23 464 486 464 486 0.96

8 9 5.1e-06 0.0004 20.7 0.3 1 23 491 514 491 514 0.91

9 9 0.0044 0.34 11.5 1.3 1 23 518 540 518 540 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.17	13	6.5	0.8	1	23	227	250	227	250	0.90
2	9	0.00036	0.028	14.9	0.1	1	23	256	279	256	279	0.96
3	9	8.6e-07	6.7e-05	23.1	1.4	1	23	285	307	285	307	0.98
4	9	9.7e-08	7.5e-06	26.1	4.3	1	23	313	335	313	335	0.98
5	9	1.3e-05	0.00098	19.5	0.8	1	23	341	363	341	363	0.98
6	9	0.0001	0.0081	16.6	1.1	1	23	369	391	369	391	0.98
7	9	2.9e-05	0.0023	18.3	0.5	1	23	464	486	464	486	0.96
8	9	5.1e-06	0.0004	20.7	0.3	1	23	491	514	491	514	0.91
9	9	0.0044	0.34	11.5	1.3	1	23	518	540	518	540	0.98

Sequence Information

Coding Sequence: ATGCTAAATCTAGGCATAGAAGAGGCAGTAGCTCCTGCCGGGGATAAAAAACATGATCGATCTGGTGGCACAGAAGCAATGCCATGTCGTCTATGCCATTCCCGTTCAGCGCTGACAAAAGAATCGCCAAACATCTATGAAGCATCTGTGGAGTTTATTAACGAAAATTCCGAGAATGAAAGCGAAAAGCTGCTGATTGCTGATGTGTGCGAAAGTGTTTGGGGTATAAAGTACAATCGCCATGAATTCCTGCCGGAACTCATTTGTGAGAATTGTTTGGAAATGTTGAAGGACTTCTATGAGCAACGCCGTTCCATGCAACAACGTGAAAACGGTCTGCAGCAGGATTTAAAGAACATCATTTCCCTGGACGCCAGATATCGACCAGGGTTAAATGGCAATCCTGGTGTATTTGAGTTTAAGGAGGGTGAAGAAGGTTGCGTCATTGTCGACGTGGATCCGGATCAGCTGTGCGAAACGACCGATGATGAGTTCATGGGCTCCGATGGCGAGGCCGAAAATGAAGATGAGGAATGGGACGATGAGGATGAGGAGGAAGCGCCAAATGATGAAGATGTAGAGATACCACTCGGCATGGACGCAGCGCAAATGGCACTCATGCAGGCTCATCTCTCAACCGATGCCGTTGTGAATGCCAATGCGCATCCCAAGAGTGCGTTCCTCTGTCAATATTGCGACCTGGCCTTCACCTTGCAGCCGGATTGCCAACAGCATGAGCTAACAGGACACGATCTTGCTGCCCCATATATCTGTAACTACTGCCAGCAGCGTTTGACGACGCGACCGGCATTGATAGCGCACATCAAGGAGCTGCACGACGCCGAGCGTCCGTATGTGTGCGCCCACTGCAACAAGGGATTCGTGCGACGTTCAGACCTGAAGAAGCACACTATTGTGCATACGGGCGTGCGTCCCTTCTCGTGCCACGTCTGCTCCAAGAGCTTCTCACGGAACACAAATCTAACCAAGCATTTGCGCATACATAGCAGCGTGAAACCCTTCGTTTGCCAGCAATGCCCTCGCTCTTTCCAGACGCCCCTTGAGCTGATGAAACACAGGCGCTCCCATGCCGAGGTCAAACCGTATCAGTGTGGTCGTTGTCCCGCCTCATTTGCACGCAAGGACAAGCTCTCCATGCACCAACACGTACACCTAAAGCGCGACGCCGAGCAGCAACAAGGTGTGCGCATGACGATGCCACCAGACCAAGTGCAGCTACCACTGCATCCTTACGTTGACAACGATGCAGCCGTAACAGGAGCAGGAGCAGCAGCACAGCCACAGACGCAAACACAGCCGGCGGCGCCGCCTTATTCGTATCCACCAGTGCAGGCAAAGATTAAGCCATCATCGAAGATGTCACGCAACTTTCGCTGCGATGTCTGTGACAGGGGATTCCAGCGAGAACGAGATCTTCAGCGTCATCGAGCGCTGCACTTGGACAGCCTGTTTGCATGCAAAATTTGCGGACAGAACTTCAATCGGCGCGAGCAACTGCAACGCCACGAGCTGGAGGTGCATGGCCCCAACTATACCTGTCCGATCTGCTGCATCAACTTCCTGCAGCAGAGCGAGCTGCAGACCCATCTAAAAGTGCACGAGCTGCAGCATAGCGTGGCCAAGAGCACCCAGGAGGCTCTCTTAGCAGCCTCATCAGTGCCGCTGACTCATTCAATGGCGGGGGAGCAAGCCGGTGCTGGCAAGCCTCCCGTCATACCGGAACCGGTGCCCATGCCCAATTTGAGAGCTGCGGAATTGTCATTCTACAGCAATATGATACCGACGATGAATTTGGGCTTTTACAGCGAGACACGACCCGAGGAGCGCAATGGAGTTTGA
Protein Sequence: MLNLGIEEAVAPAGDKKHDRSGGTEAMPCRLCHSRSALTKESPNIYEASVEFINENSENESEKLLIADVCESVWGIKYNRHEFLPELICENCLEMLKDFYEQRRSMQQRENGLQQDLKNIISLDARYRPGLNGNPGVFEFKEGEEGCVIVDVDPDQLCETTDDEFMGSDGEAENEDEEWDDEDEEEAPNDEDVEIPLGMDAAQMALMQAHLSTDAVVNANAHPKSAFLCQYCDLAFTLQPDCQQHELTGHDLAAPYICNYCQQRLTTRPALIAHIKELHDAERPYVCAHCNKGFVRRSDLKKHTIVHTGVRPFSCHVCSKSFSRNTNLTKHLRIHSSVKPFVCQQCPRSFQTPLELMKHRRSHAEVKPYQCGRCPASFARKDKLSMHQHVHLKRDAEQQQGVRMTMPPDQVQLPLHPYVDNDAAVTGAGAAAQPQTQTQPAAPPYSYPPVQAKIKPSSKMSRNFRCDVCDRGFQRERDLQRHRALHLDSLFACKICGQNFNRREQLQRHELEVHGPNYTCPICCINFLQQSELQTHLKVHELQHSVAKSTQEALLAASSVPLTHSMAGEQAGAGKPPVIPEPVPMPNLRAAELSFYSNMIPTMNLGFYSETRPEERNGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502679;
90% Identity: iTF_00479628;
80% Identity: -