Basic Information

Insect: Drosophila mimica
Gene Symbol: HIVEP2
Assembly: GCA_037043585.1
Location: JBAMBE010000984.1:192437-200946[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0016 0.1 13.1 0.4 2 23 279 300 279 300 0.98

2 8 0.00024 0.016 15.6 3.2 1 21 306 326 306 330 0.90

3 8 0.011 0.68 10.5 0.2 1 19 1001 1019 1001 1022 0.93

4 8 2.9e-06 0.00019 21.6 2.0 1 23 1777 1799 1777 1799 0.99

5 8 1.2e-05 0.0008 19.7 5.3 1 23 1805 1829 1805 1829 0.92

6 8 0.00056 0.036 14.5 3.5 2 23 2314 2335 2314 2335 0.97

7 8 0.00085 0.055 13.9 1.2 1 23 2341 2365 2341 2365 0.91

8 8 0.0027 0.18 12.3 2.7 1 23 2386 2410 2386 2410 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0016	0.1	13.1	0.4	2	23	279	300	279	300	0.98
2	8	0.00024	0.016	15.6	3.2	1	21	306	326	306	330	0.90
3	8	0.011	0.68	10.5	0.2	1	19	1001	1019	1001	1022	0.93
4	8	2.9e-06	0.00019	21.6	2.0	1	23	1777	1799	1777	1799	0.99
5	8	1.2e-05	0.0008	19.7	5.3	1	23	1805	1829	1805	1829	0.92
6	8	0.00056	0.036	14.5	3.5	2	23	2314	2335	2314	2335	0.97
7	8	0.00085	0.055	13.9	1.2	1	23	2341	2365	2341	2365	0.91
8	8	0.0027	0.18	12.3	2.7	1	23	2386	2410	2386	2410	0.92

Sequence Information

Coding Sequence: ATGACGCTACAGCAGGTGGCAAGCAGCGCAACGAGCaacgtggcaacaacaacaaccacaataataCCAGCCACAGccaacaccaccagcaacaacaaccagaacaataacaacaacaacaaccagaacaacaatcacaatgtgttggccaacaacaacaacaacaacagcagcagcaacgagtATCAAACaacggtggcagcaacaattgtcgATGGCTGGGCGAGCTCAACCACTTTGcgttatttgcacaaaaagtTTAAGCGGCTGGCGAGCACCACCGAGCCGGAGTCGGTCGATGCAATGGAGGCGGTTCGCACCACATCGCTATCATCGAATAGCTCGCTGTCGCCACCGCTGCCAGTGGTGGCTGCTCCTCCTCTGCTCAATGGACATGTGACGGTGAAGGTTGCTCCCTTGCTGCCGGCAAGAAATTTAGAATTCAGTGCCAATTTTCGTAAAaacgacaacatcaacaacaacaacaacatcagtaataacaataacaacagtcACGatgagagcaacagcagcagcaagcatagcaatgttggtgttgctggtgaGCCTCGAACACGCACGCCCCTCAGCAACAgtaatagcaacagcaatattAACTATGCCAGCAATGCAACACTGTCGCCAGCAACATTCgcacagcatcagcaacaaacgcagccaacgccagcagcaacagctgttgtcgttgcagcaacaacaacaacaactgtagcagcaccaccagcagcagcagcagcaacaacaataatacaaacagcagcagcagcagcaacagcaacagttgcaggaTTAGGCGAGAAAACTAGTCGCCCCAAGTGCCCCTATTGCAATCTGATCTGTGCCAAGCCATCGGTGCTGGAGAAGCACATTCGTGCCCATACCAATGAGCGACCGTATCCGTGCAACAACTGTGGCATCGCCTTCAAAACGAAGAGCAACCTGTACAAACACTGCCGCTCCCGTTCCCATTTGGCGCGAATGCGCGGACTCGATGTGCCGGCCAACGAAACGGACGGACTCTCCGACCAGGATGGCGACGGGGAgctgagcaacagcagctccgAACTGCTAAGCGTCGAAGTGCTGAGTCGCACAGATTCGCCTTATGATGAGGCAATGGCTTCGCCAacgccatcgccatcgacGCTGTCGGCGGCGAAGAGTACGTATCTGCAACAgccgcaactgcaacagcatatgctgcaacagttgccgctGGGCTCACCTGCCGCCGGAACACTGCCGCCCGCCCCGCCCGCTGACTCGCTGCACTCGGCGACCGCCCAGCATCGCCAGTCCATCGACTACAAGCCATACAAGCCCAAGTTCCACAATGCATCCCTCTATGCGCCCGGCACCCtcaaggagcaacagcaacagcagcagcaacagcagcaacaacagcagcaacaacagcagcaggcactgcaacagcagcagacgctgctgcaaccacaacagcagcaacataagcTGTcagcgcagcaacagcagcagcagcagcaaccatcGCTGACGCATCCAACGCTTTCGCCCAGCACCCAGTTGAAGCTCAACAATCACATCAACTCGCatcagttgcaattgcagctgcagcaccaacaccagcagcagcagcagcagcacatgcACGCCCAGcaatcgctgctgctggctgcggCAGCAACCAATCCGGTTGCATTGTCAGCtttgccaccgccgccgccgggTGTTTATTATTTGGGGCAGCCGCAGTATTACAatccaactgcagctgcaatgCATCAGCATGCGATGGCCATTCAGCagatgcaactgcagcagcactttcagctgcaacagcaacagcagcaacagcagcagcaacaacaacagcagcagcaacagcagcagcaacaacaacagcagcagcagcagcagcatcaccaacagcatcagcaacaccagcaacagcatcagcaacaccagcagcagcagcagcaacactcgcCGTTGCTGAAGgcgccacagcaacaacagcaacagcagcagCTGTTGCGCTCCACTAGCCAACAACAGGCGGCAGccattgcaacaacagcaacgctgCCCGCACCTGCCACACCCAACCCGCCAACCAATCTGAGCAGCTTTGCCAGCACAAGCGGCGGCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCCAACCTGATCTCACAGAACGAGGCGATTGTGGAGAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGTTCGCGCAGCttcaacaatgccaacaacaacaacaatagcagcagcaacagcaacagcaacagtataCCAACAACAGCGcacgccaacagcaacagcagcaacagcaacaacagcaatcaacaGCTGGGCGAGACTAAAGTGAACCTGGCACAGGCCATAgtacaaaagcagcaacaacagttgcagcagcaacaataccaattatacttgcaacagcagcagcagcaacagcaactggaacCGCCAGTAAACGGCTGGCtgaagcgcagcagcagcagctctggGAGCAGTTCGGCCAGCAGCGGCTACGTCAGCGTCAAGGGCACAGCGACACCAACACCCACCGTCGCAGCCACGGCAAATGTgaaacagttgcaacaattgccgccgccgccatcgccgttgccgttgcaacagttgcagtatCGCCAGGATCCGTCGACGCCAGTGCCcaagctggagcagcagcagcagcagcatcagcagcagttgcagcaacccTTAGCACCCAATCATGCCCAGCCACTGAATTTGTCTGCCAAGCCCAAGCCACTGGCGATGCCAACAAAACCACAGCAaccggcagcaacaacagtcggagcaacaactgttgccaagttggcaacaacagcagcccagGCGGCTACACCGAATATATCGATAATCAAGAATCTGCTGTTGAATGCACGTGGCTTGGCGGTGCCAATTGGTGAGGGCGATGATGCCGTCTACTCCTGCCCCATCTGCGCCAACGAGTTTCGCAGCGCGGACGAGTTGAAGCACCACAACAGCACCTACTGCCAGGATGCAAACAGCAGTGCCCCGATCAGTCCAGCCTCATCGCCGAGCACCAAATACTTTCGCTCCAATTCCATATCGTTTACTCTGCCGGAGCTGCAGTCGCACATGGCCAACTCGAAGAATCCTTTGTCGCTAGCCAAGCTCGCCAAGGTCGCCTGGTCGCAGCTAAAAACCAAGCCGAGCAGCCTGGTTCTCAGTCGTCTCAGTGCGGCTCAATCACCCGCACGCACCTCAACCATCACAGCagccaccaacagcagcagcagcagcaacaacaacaaccaccacataaacagcaacatcagcagcagcagcagcggcagcaacatcaacaatcacataccaacagcagcagcagcagcaacaacagttgtaaTCCCGCCCAGCATCGATGCCTCCAGCGTTTCTTTGCGTTTTGTGGACGCACCGCTGCCATCGCCTGGTCCACTGCTCGGCAAGACACCGCTTGTGGATTATGCAGCGCCCCGCAAGGCGCCCGATGCCCAGGTGGTCATCACGAAAATGCACGAGGATCGCTTGGAGAACATCATCGTTGAGATGCCACCGAAACGTCTGAAACTGAGCAGACAACCAACATCGTTCACAACATCTATTGTCGATAGGCTCTTTGCTGGCAATCCGGAGTTGCAGTTCAGTGCCAAGGAGGAGCGTCTGCGTCGCTTTACCTCATCCGGCGGCACCATGATACCCATTTCCGAATGTCCCGAGCTGGACCAGAGTCCCAAAATGATACGCACTCCTCTGCTGTCCGGCGGCAGTTTCCAGGACCTCAAGGAGCGCAAACTTCTcgctgccaacaacaacaacaacaacaataataataataataataacggtTTTCTGCTCAGCGCCTCAAACGCGCCgcatcattttcaatttcccaTCAATTCGATAACCGCCTTCAATCCACTCACCCTGCCACccatgagcagcagcagcagcagcgccagcggcATCAACAGCAATCTTGTGGATAAGGCGATACCCTATGTGCCTGGCATACCCGGTCCGGGCAGCTTGTCGTTGCTGCCACCGCCACTGCAGATGCAGCGTGGACGCAGCCCCACTCGCAAACAGCCCAGTCCCAATTCGAATCCCAATCTTAATCTTAATCTCAATCCGCTGCTGGTAGTTGAGGGACCGCTCAAGGCACTCTCGCCCTTCGGTGGCGTTCAGAATTTGCCCAGCGAATTCAGTCGGCAGCCACCAACGCCAGCCCAGCGCAATGCGCTCCAAtggaccaacaacaacaacaacaacaacagcagcagcagcagcagcaataagaTGCCAGTGATTGTTGCTGACAAGAAGCAACCATTCAATTTTCTACGCATGGCGGACAATGTGAAGAACTCGACTGTGCAGGAGCAACAGACCCAATCCCAGGCAATGGGTTTGCCGGAGGTGCGTCACTTCAATTTCGATAATGTGAACAAATCGCAGGAGGCGCTGGCGCCGCTGCACGTGGACACGCCAGACGAGGcgactgcagcaacagcagcagcactcaaaacaacaactgctattccagcagcagcagctgcagcaggagcagcaacaaccaccacaACTAGCATCGCCAAGTCGAAATTCTTGAGACCCACCAGTCTGCCGCTGAAGCCGGGTACCTTTACGCCGAAGCGGCATCATGGCATCACCCCGACTGCGAATACCCTGCCCCTCATCTCACCGGAAACGCCGCGACCCTCCAAGTCGTGCGTGCAACTCTATCTGAATGGACACGCTTACACCTATCTGGGATTGAAGTGCAGCACAAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCGTCGTATGTCGCTGGGATGCACAAACTGTCGATGTACAGCGTGTGGCAGGTGTGCGAGGAGAATCAGCCGCATCCGCTCGGCTTCAAGCCCAAACAGGTGATGGCTCTGTACGATTCCCGGCAAAAGATGCTCGGCACTGGCTGCACCACAGCGATGGCGGGTGCCGGCAAACTGCAGTACTCCGTCTTCAGTTCACAGGAAACGGTTAGCACCTGCTCCACCATCGCCAACGGGCAGAGCAAGTTCTACCAGCACCAGTTGAAGCAGCCACCGGCAATTGGGGCGCTCAGCGAGGCGAATGTGGCGGCAAAGGCCAGCGAGGAGGCGGCTGCCAAGAAGCTGGAATCGGGTCAACTGCTGGTCGGCGGTTACGAGTCGCATGAGGATTACACGTACATACGTGGACGTGGGCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATACGCTGCAAGAAGCCCTCGATGCTCAAGAAGCATATACGCACCCACACGGATGTGCGTCCCTTCACCTGCAGTCACTGCAATTTCAGCTTCAAAACCAAGGGTAATCTCACCAAGCACATGCAGTCGAAGACGCACTTCAAGAAATGCATCGAGCTGGGCATCAATCCGGGTCCGATGCCCGCCGACGGCGAATTCCTTGATGTCGATGTGGACTTTGATCAGCAATCGTCGACATCGGCGGGCGGACGCACCTCCTCCATGGCCGGTGAATCCGATTCGGATGACTACAGCGACAACGAGTCCGAGAGCAGTGACACCGATGAGTCCAAGTCGCGCATGAAGGAGCACGAGGCGGCGCGTGgtctgctgtcgctgtcgatGACGCCACCGATACCGCAGAGTGTTTCACCGTATCCGGCACTGGTGCAGGATACGCCGGCTGCCAGTCCAGCGAACAGCATTGGTTCGTCGGCGGGCAGCGCAGCTGGCGGATCGCAGCCGAAGCGTCAGGTTTGCTCGTTTACGTCGCCGAAGCCGCCGTTTGACTACCAGAAGCAGGAACAGTATTACTCTAATCCCGAGGAGTCAAAACCCAAACGCGGTGTGCCCAACGACGAGAGCAGCGCACCCATGGATCTGACCAAGCCACGTCCAATGCCCAGCATTTCAGTTGCCGCCTCTTCGCCGGTGCCGGAGCAGACGCCCAAATCGCAGGCACAGCAGATGCGAGACGTCATCTTTGGGGCGGGCAACAATGAGTGTGGCTTCATGAAGACCCTGATCTCTGTTTCCGACAAGGTGCGCATCTCTGCCGAAATTGAGGAGCAGGCGAAGCGCGAAAGCGAAGGCGAAGATGTCCTCTTGCAGACCTACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAATTTAGTCGCAACTACCTAATtacctccaccaccaccaactccaactccaactgcatctccacaagcagcagcagcaccagctccagctgcatCTCCAGCACGAGCAGCATTAGCTGTGTGGTGACCACGCCCATTGTTAATAGCAAACCACTGTTGAACATCGCGGAGCTGCCCAGCATTGAGGTGCACGAGGTGAAGACACCAGAGTCGCCAACGTCAACGCCATGCCTCAAATCCGCCGAGGAGAGTGAGGAAAGCGAAACGCAATCGGATCAGGAAAAGCCAATCAAAATGTCGACCACTCCTGTCAATGTATCCGTGTCCGTTTCAGTCCCTGCACCCGTTGCCAACGCCAAGTGCAGCGCGGAGATTCAACAGCCGCACAATGCCAATTTGCCTGCTGCAGTGCAGCAGCCAGATGCCACCGATTTTAGTGGCgtactcagcagcagcagcagcagcagcaacaacaaaaatagcagcagcagcagtggatcAACTGCACCCACACGCATTGTGGTCGTCGGAGAGGATGGCTTCAAGACGACTCCAACCAGTGCCAGCAACGAATTGCAGtctgcaggagcagcagcaacagctgcaggagCAACTTATGCGAATCGTGTGGtggcaccaccaccgccgccaatAGCGAGCGATGCGCGACCCACTTGCACCGTTTGCAACAAGACGTTCCAGCGGACGCATCAGCTGTCGCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGCACCCAGGGTCATCTGCAGAAGCACGAGAGGAGCGAGGCGCACAGGAACAAGGTGATGATGACGTCGACATTTGGTGTGCCCACCACATCCAATCCGCGTCCCTTCGAGTGCACCGATTGCAAGATTGCGTTTCGCATCCACGGCCATCTGGCCAAGCATCTCCGCTCCAAGACGCATGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTTGGCACCTATGCGGAGATCGAACGTGCTGGCATCAGTCTGACGGAGATCGATACCAGCGACTGTGACAATTCGCTCATCTCGCTGAAGCTGCTGGCGCAAAAGCTGCTCGAGAAGGATCCCAACAAGCTGAGTGGCTACACAACGCCGTCGGGCATGCTGCAGCTGTCGGTGGATGCGCCGGCTGCCGGTCAGGATAGCGCTTCCGAGGATGGCTTTAGTGCGGCGAACAGTGCCGCCGCCTCGGCCATTGCCTCGCTGGACAACGACAGTGCGGGCAACACACCAAAGCGTGCCAGTTCCATGTCCGAGGATGAGACGCTCACCaacggactcggactcggactcggtcACAGTCACAGCCACGGCCACAGTCTAAAGCGACGTCTGCAGAACAGCAGCTTCAGCAGCAACGGCGATGAGAGCGACAATCCAACAGATGCCACCGGcgagaAGCGAGCGAGAAGCAACacaaatgaaatcattttgcCGACGCCGCCCACCTGA
Protein Sequence: MTLQQVASSATSNVATTTTTIIPATANTTSNNNQNNNNNNNQNNNHNVLANNNNNNSSSNEYQTTVAATIVDGWASSTTLRYLHKKFKRLASTTEPESVDAMEAVRTTSLSSNSSLSPPLPVVAAPPLLNGHVTVKVAPLLPARNLEFSANFRKNDNINNNNNISNNNNNSHDESNSSSKHSNVGVAGEPRTRTPLSNSNSNSNINYASNATLSPATFAQHQQQTQPTPAATAVVVAATTTTTVAAPPAAAAATTIIQTAAAAATATVAGLGEKTSRPKCPYCNLICAKPSVLEKHIRAHTNERPYPCNNCGIAFKTKSNLYKHCRSRSHLARMRGLDVPANETDGLSDQDGDGELSNSSSELLSVEVLSRTDSPYDEAMASPTPSPSTLSAAKSTYLQQPQLQQHMLQQLPLGSPAAGTLPPAPPADSLHSATAQHRQSIDYKPYKPKFHNASLYAPGTLKEQQQQQQQQQQQQQQQQQQALQQQQTLLQPQQQQHKLSAQQQQQQQQPSLTHPTLSPSTQLKLNNHINSHQLQLQLQHQHQQQQQQHMHAQQSLLLAAAATNPVALSALPPPPPGVYYLGQPQYYNPTAAAMHQHAMAIQQMQLQQHFQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHQQHQQHQQQHQQHQQQQQQHSPLLKAPQQQQQQQQLLRSTSQQQAAAIATTATLPAPATPNPPTNLSSFASTSGGMQVNVEKVQEHISNLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNNSSSNSNSNSIPTTAHANSNSSNSNNSNQQLGETKVNLAQAIVQKQQQQLQQQQYQLYLQQQQQQQQLEPPVNGWLKRSSSSSGSSSASSGYVSVKGTATPTPTVAATANVKQLQQLPPPPSPLPLQQLQYRQDPSTPVPKLEQQQQQHQQQLQQPLAPNHAQPLNLSAKPKPLAMPTKPQQPAATTVGATTVAKLATTAAQAATPNISIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKHHNSTYCQDANSSAPISPASSPSTKYFRSNSISFTLPELQSHMANSKNPLSLAKLAKVAWSQLKTKPSSLVLSRLSAAQSPARTSTITAATNSSSSSNNNNHHINSNISSSSSGSNINNHIPTAAAAATTVVIPPSIDASSVSLRFVDAPLPSPGPLLGKTPLVDYAAPRKAPDAQVVITKMHEDRLENIIVEMPPKRLKLSRQPTSFTTSIVDRLFAGNPELQFSAKEERLRRFTSSGGTMIPISECPELDQSPKMIRTPLLSGGSFQDLKERKLLAANNNNNNNNNNNNNGFLLSASNAPHHFQFPINSITAFNPLTLPPMSSSSSSASGINSNLVDKAIPYVPGIPGPGSLSLLPPPLQMQRGRSPTRKQPSPNSNPNLNLNLNPLLVVEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTNNNNNNNSSSSSSNKMPVIVADKKQPFNFLRMADNVKNSTVQEQQTQSQAMGLPEVRHFNFDNVNKSQEALAPLHVDTPDEATAATAAALKTTTAIPAAAAAAGAATTTTTSIAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGTGCTTAMAGAGKLQYSVFSSQETVSTCSTIANGQSKFYQHQLKQPPAIGALSEANVAAKASEEAAAKKLESGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPALVQDTPAASPANSIGSSAGSAAGGSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRGVPNDESSAPMDLTKPRPMPSISVAASSPVPEQTPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEIEEQAKRESEGEDVLLQTYIKEQALQHAKMKQSQFSRNYLITSTTTNSNSNCISTSSSSTSSSCISSTSSISCVVTTPIVNSKPLLNIAELPSIEVHEVKTPESPTSTPCLKSAEESEESETQSDQEKPIKMSTTPVNVSVSVSVPAPVANAKCSAEIQQPHNANLPAAVQQPDATDFSGVLSSSSSSSNNKNSSSSSGSTAPTRIVVVGEDGFKTTPTSASNELQSAGAAATAAGATYANRVVAPPPPPIASDARPTCTVCNKTFQRTHQLSLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCDNSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLSVDAPAAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPKRASSMSEDETLTNGLGLGLGHSHSHGHSLKRRLQNSSFSSNGDESDNPTDATGEKRARSNTNEIILPTPPT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00513682;
90% Identity: iTF_00522436;
80% Identity: -