Basic Information

Insect: Drosophila mimica
Gene Symbol: -
Assembly: GCA_037043585.1
Location: JBAMBE010000665.1:1613193-1617742[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.00052 0.034 14.6 0.9 1 23 214 236 214 236 0.97

2 25 0.0054 0.35 11.4 5.0 1 23 242 264 242 264 0.98

3 25 0.076 4.9 7.8 1.1 2 23 297 318 296 318 0.96

4 25 0.0013 0.085 13.3 1.7 1 23 393 416 393 416 0.94

5 25 0.2 13 6.4 0.6 2 22 426 446 426 446 0.96

6 25 4.2 2.7e+02 2.3 0.4 1 19 455 473 455 475 0.91

7 25 0.0046 0.3 11.6 0.5 1 23 597 620 597 620 0.96

8 25 0.008 0.52 10.8 0.1 1 22 629 650 629 650 0.95

9 25 0.0031 0.2 12.1 4.3 1 23 659 682 659 682 0.97

10 25 6.4e-05 0.0042 17.4 0.4 2 23 698 719 697 719 0.97

11 25 1.4e-05 0.00093 19.5 5.2 1 23 725 747 725 747 0.98

12 25 0.014 0.9 10.1 1.2 1 23 886 909 886 909 0.95

13 25 0.0049 0.32 11.5 2.2 1 22 916 937 916 937 0.96

14 25 0.29 19 5.9 0.7 1 23 946 969 946 969 0.88

15 25 5.9e-05 0.0038 17.5 1.6 1 23 993 1015 993 1015 0.97

16 25 0.00044 0.029 14.8 0.7 1 23 1022 1044 1022 1044 0.98

17 25 0.13 8.5 7.0 0.0 2 21 1071 1090 1070 1091 0.94

18 25 0.039 2.5 8.7 4.0 1 23 1136 1159 1136 1159 0.96

19 25 0.0045 0.29 11.6 1.5 1 23 1196 1219 1196 1219 0.96

20 25 0.014 0.92 10.1 3.1 1 23 1246 1269 1246 1269 0.97

21 25 1.3e-05 0.00087 19.6 0.1 2 23 1290 1311 1289 1311 0.95

22 25 4.6e-05 0.003 17.9 2.9 1 23 1317 1339 1317 1339 0.99

23 25 4.2e-06 0.00027 21.2 2.3 1 23 1345 1367 1345 1367 0.97

24 25 2.8e-07 1.8e-05 24.8 2.6 1 23 1373 1395 1373 1395 0.99

25 25 0.00068 0.044 14.2 0.3 1 21 1401 1421 1401 1425 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.00052	0.034	14.6	0.9	1	23	214	236	214	236	0.97
2	25	0.0054	0.35	11.4	5.0	1	23	242	264	242	264	0.98
3	25	0.076	4.9	7.8	1.1	2	23	297	318	296	318	0.96
4	25	0.0013	0.085	13.3	1.7	1	23	393	416	393	416	0.94
5	25	0.2	13	6.4	0.6	2	22	426	446	426	446	0.96
6	25	4.2	2.7e+02	2.3	0.4	1	19	455	473	455	475	0.91
7	25	0.0046	0.3	11.6	0.5	1	23	597	620	597	620	0.96
8	25	0.008	0.52	10.8	0.1	1	22	629	650	629	650	0.95
9	25	0.0031	0.2	12.1	4.3	1	23	659	682	659	682	0.97
10	25	6.4e-05	0.0042	17.4	0.4	2	23	698	719	697	719	0.97
11	25	1.4e-05	0.00093	19.5	5.2	1	23	725	747	725	747	0.98
12	25	0.014	0.9	10.1	1.2	1	23	886	909	886	909	0.95
13	25	0.0049	0.32	11.5	2.2	1	22	916	937	916	937	0.96
14	25	0.29	19	5.9	0.7	1	23	946	969	946	969	0.88
15	25	5.9e-05	0.0038	17.5	1.6	1	23	993	1015	993	1015	0.97
16	25	0.00044	0.029	14.8	0.7	1	23	1022	1044	1022	1044	0.98
17	25	0.13	8.5	7.0	0.0	2	21	1071	1090	1070	1091	0.94
18	25	0.039	2.5	8.7	4.0	1	23	1136	1159	1136	1159	0.96
19	25	0.0045	0.29	11.6	1.5	1	23	1196	1219	1196	1219	0.96
20	25	0.014	0.92	10.1	3.1	1	23	1246	1269	1246	1269	0.97
21	25	1.3e-05	0.00087	19.6	0.1	2	23	1290	1311	1289	1311	0.95
22	25	4.6e-05	0.003	17.9	2.9	1	23	1317	1339	1317	1339	0.99
23	25	4.2e-06	0.00027	21.2	2.3	1	23	1345	1367	1345	1367	0.97
24	25	2.8e-07	1.8e-05	24.8	2.6	1	23	1373	1395	1373	1395	0.99
25	25	0.00068	0.044	14.2	0.3	1	21	1401	1421	1401	1425	0.91

Sequence Information

Coding Sequence: atgttgcCGACGAATGTTTGTCGCACGTGTGCTCTCCAAGATGACAACTTGTTTGCACTGGCAACGCGGAGTGAGAAATACGCAAAGAAAAGTATTTGCGACATGCTGCACGAACTAACACAAAACGATCCACTGCTGGAGCATACATATGATAAGCTACCGCAGCATTTGTGCGGTCAATGCTTGAGTCAGTTGGAAGCTGCTTATGCATTTGTGCTGCAGGCCCGCGTGGCGCaggagcaactgttgctgcagctacGTAATGGATTGCAGACACAGTGCCTGGACGAAACACCGATCGATATAAGCATAGAACACATCAAAATCGAAACAGACATTGACCTACATGCGGACACAGCTGATGCAGTCGATGCCGAGTTGGAGGATGAGCAGGAGAAGCAGGTTGTCTTAAAATGTCAGCCGGAAACTGATAGCGACAGCAGTCAGGTTATTTTGAAAGACCATGACGTTGATATCAGAATACCGCAGCTGCGGCGCAGTGCACGGCGAGCCAAACTGAGCACAGACAGCGAAAATGACTCAATCTCTGAACAAGTGAAACCGTTGCCTGTTAAGCGTGGACGCGGTCGTCCCGCACGTCTAGCCAAGACGGAGACGACCACCAACGAAAATGGGCGACATGTGTGCGAGGTATGTGGCAAGACCTTCTCTTGGTATCGCGACATGCAGCGCCATGCGCGCATCCACTTCGAGCAGGCGGGATTTGTGTGCGAGCACTGCAGCAAGAAGTTTCTGCGGAAGGACAAGTACATGACCCATCTGCGATCGCACAAGAAGCACGTGGCCACAGATGGACACACACTGCCACGGAGCAGCGAGTGGCGCTACGCGGAGCGTCTATACAGCTCTGGCAGATTAATGCGTGTGGAGTGCAAACTGTGCGGATTGAATTGCCAGCGCATTCGGGAGTTGCGCGAGCACCTGTCGAGTCATGTTCACATTGAAACATTGTCGAATCTCAGCATGGACAATGATGTCATCCGGGAGCATTTTGGAAGCCAATTGGATATGCAGCAAATTAAGGAACAGGTGTGCACGCAAATTGCCAAAGGTCGCGAACAACTGGAGAATTACGGCGCCGTGGTGAATGCCTACGGCTATGAGCTGTGCCTCAGCGACTCGGATGAGGAGGACGATGAGGAGCTGGCTGACAAATATCAATGTCTGCGTTGCAATGTTAACTTTGCACGCAAGCATCAACTCGTCCGTCACACACTCGAGGAGCACACGGACAGAAAAGAGACTCCTTTGGAACGCTGCAATATATGTCAAATTGGCTTTGTTTGCGCCAAGCTGCTGGAACAGCATCAGCGCACGCAGTGCCTCAATCCGTTGAAGCGTTACAGTTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAATCTGCAGCAGCATGCATGCTGCAGACTGCAACAGGATCTGCAGCAGGAATTGCAGCATTCGcatcaggagcagcaacaggcacCTCATCGCCAGATCCAATGTTGTCTGTGCAATAACCAACCCGCCAGCATGGCTGCCCTACGATCTCATTTACTCACTCATCGCGATGGACACACGGACATCGATCCGCACCAGCAGTCTGCTTTCTTTCGCACCTATTACCAGGACGACGGCACCAGCAGCCTGTCGGAAATCGGGGCACGCATCGCTGGCGACTTTGAGGCGCAGCTTTATGGAAGATATTTCAATGCGTGCACGGACAGCGGTCAGGAACTGGACTTCAACGACTCCGACAAGGAGTGGAGCGATGCGCCCGCTCTGCACAGCTGTGCCGTGTGTGGCGAGAGTAGAATCCGCCTCGATCAACTGCTCCAGCATCAGCAGAGCCAGCACATTGAGCTGGCGGGCGGACTGCCTCATGTATGCTCAGATTGTGGATTGGGCTATGTGGCAGAGTCGCTGCTGAAGCAGCATCGTCGTCGCATCTGCGCTAAGCTGCATGCCAAGTACCAGTGTCCACATTGCAGTCAGCGCTTCTATTGGCATTCCAACTACGAGCGCCACATTCAGGTGCAACATCCTGCGGATAGGCACCATgggcaggagcaggagaagaGCAAGTTGCAGTGCAGCGAGTGCGATAAGGTGTTCATCTGGCCTAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCACAGGTGCAGTTCGAATGCGCCCACTGCGATCGCAAGTTTCATCGCAAGGATGGTCTCAAGTCGCACATGCGGATGCACGGCGAGCTGCCGACGTCATCTCTCAGTGAGCAACTGCAGCGCCTGCCGATGGTCTTGGGCCAGCTGTGTCGCCCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTGTCCCAGCACACAAAGATCTCCGATTTGCGTACGCACTTGACTAGCCATCAGTTGACCCTGTTTTTGGCCGAGGAGCGAGGCATCACAAACATTTGTCGGGCTCTCTATCCGGAGTTGAACACGCCATTGGATCAGCAGGCATTAATGACGCGGATCCAACGTGATCTGGCCAATGGCCGGGAGCTGGAGAGATTCGTTTCGATAACCAACGAGGCGGGCATCGAACTAAGCCTGGACAGCAGCGAAACGGACACGGATTCGGATTGTGCAGCAGATACCGAACGGAGCAGCACGGAACGCCGTTACAGCTGTGAACTGTGCCAGGTGCAGGTGACGCGCAAACATCAGCTCTATGCCCACCAGCTGGAACAGCACACGTGGCACCGGACGACGCACGTCTGTAGCCATTGCCAGGCGAGATTCGTGAAtgagcagctgctggagcATCACTATCGCACCCTCTGCCGCAATGCCCAGCGGCGTTTCCTGTGTCGCAAGTGTCCGTTACGCTTTCGCTGGCGCGATAATCTCAAGCTGCATAATACTGTTGCGCATCAGGAGCAAGGGAATGTCGAACAGCAGTCCAATGTGGACATTCAGTTGCGTATGCTGCCCGTGGTTAGCTACGACTGTGTCGAGTGCAAGCGTAgcttcaaaatgcaaaaggatCTCACACGGCACACCCTGATGCATGCCCAGGAGTCGAGCATATATCGGTGTCGCTGGTGCGCTCGACGCTTCTATCGGGAGGCGAATCTGCTGCAGCATATCGAGCGCCATGGCATCAGCGCCGACCAGCTGCCCTATGCGGAGGCCCTGCTCAACGCCAGTCGTCATCCGCACGGCCCGAAGTGTATTCAGTGTCGCGTGTGTGAATTATCCTTTGGCAGCATTGCGGCACTGCGATCCCACCTGCAATCGTCGCCAGTTGGCACTCATCATCCGATTGAGTCCATGGCCAACTATTCGATCACCAATCAGCTGGGCTATGAGCTGCACCTGGATGATTCCGAAACGGATGAGGAAGCCAAGCCGGGAGGCACTCCGGCGCATTACACGTGCGGCATGTGCCAGCTGCGCTGTGTTCGCAAATTTGAActacatcagcatcagcaggccATGCATCGCCTGGAGCGCATCGCCGACGGCTGTGATCTGTGCATCTTCAAGAGCGTATCTCCCGATCTGATTGCGTATCATCGGCGTGTGCTGTGCGAAAACACGGAGAAGCAGTTCAAGTGCACTAAATGCAGCTACAAGTTCATGTGGCAATCGAATCTGGCACAACACATCCAACTGCAGCATCCCAGCAGCGATGAGTCgacatcaaaaacaacaatgccCATGCCCGTAGCCGACATTGACAACGTCGAGAGCACCGTCTTCCAGTGTGGTCAGTGTCCAAGTAAATACAATCGCAAGGATCGCCTCACCGCCCATGTGAAAAAGTGCCACACAGCTGGCGCAACTGCATCAACAAAATCACCAGCTGTTGCCAAGCAGCAGAAGAGTTTCCTGTGTGCCTTTTGCGGCAAGGCGGTGAGCTCATCCTCAAATTTAATCATACACATACGTCGGCACACCGGCGAGAAGCCGTTTAAGTGTGATTACTGCGACATGGCCTTTCCGCGCTCCTCAGATCTCCAATGCCATCGACGCACCCACACCGGCGAAAGGCCTCACATTTGCACCGTCTGCAAGAAGGGTTTCGCTCGCTCCTacaagctgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACCCTCCACATCCGCCGCCACACGGGCGAGCGACCTTATCAGTGCAATACTTGCGGCGAGCGATTCATTCAAGGCACAGCGCTCAAGAACCATCGACTGCAGAATGGCCACTATGAGACGGAAGTGGATCAATCGAAAGATGACTAA
Protein Sequence: MLPTNVCRTCALQDDNLFALATRSEKYAKKSICDMLHELTQNDPLLEHTYDKLPQHLCGQCLSQLEAAYAFVLQARVAQEQLLLQLRNGLQTQCLDETPIDISIEHIKIETDIDLHADTADAVDAELEDEQEKQVVLKCQPETDSDSSQVILKDHDVDIRIPQLRRSARRAKLSTDSENDSISEQVKPLPVKRGRGRPARLAKTETTTNENGRHVCEVCGKTFSWYRDMQRHARIHFEQAGFVCEHCSKKFLRKDKYMTHLRSHKKHVATDGHTLPRSSEWRYAERLYSSGRLMRVECKLCGLNCQRIRELREHLSSHVHIETLSNLSMDNDVIREHFGSQLDMQQIKEQVCTQIAKGREQLENYGAVVNAYGYELCLSDSDEEDDEELADKYQCLRCNVNFARKHQLVRHTLEEHTDRKETPLERCNICQIGFVCAKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLQQHACCRLQQDLQQELQHSHQEQQQAPHRQIQCCLCNNQPASMAALRSHLLTHRDGHTDIDPHQQSAFFRTYYQDDGTSSLSEIGARIAGDFEAQLYGRYFNACTDSGQELDFNDSDKEWSDAPALHSCAVCGESRIRLDQLLQHQQSQHIELAGGLPHVCSDCGLGYVAESLLKQHRRRICAKLHAKYQCPHCSQRFYWHSNYERHIQVQHPADRHHGQEQEKSKLQCSECDKVFIWPKDLTRHKRMHQSQVQFECAHCDRKFHRKDGLKSHMRMHGELPTSSLSEQLQRLPMVLGQLCRPNGCKQIKCMICLSQHTKISDLRTHLTSHQLTLFLAEERGITNICRALYPELNTPLDQQALMTRIQRDLANGRELERFVSITNEAGIELSLDSSETDTDSDCAADTERSSTERRYSCELCQVQVTRKHQLYAHQLEQHTWHRTTHVCSHCQARFVNEQLLEHHYRTLCRNAQRRFLCRKCPLRFRWRDNLKLHNTVAHQEQGNVEQQSNVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGPKCIQCRVCELSFGSIAALRSHLQSSPVGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPGGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCDLCIFKSVSPDLIAYHRRVLCENTEKQFKCTKCSYKFMWQSNLAQHIQLQHPSSDESTSKTTMPMPVADIDNVESTVFQCGQCPSKYNRKDRLTAHVKKCHTAGATASTKSPAVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQNGHYETEVDQSKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00610043;
80% Identity: -