Basic Information

Gene Symbol
ZNF131
Assembly
GCA_037075245.1
Location
JBAMCH010000023.1:11715191-11717283[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 1.5e-06 0.00011 22.5 0.8 1 23 391 413 391 413 0.98
2 7 2e-05 0.0015 19.0 0.8 1 23 419 442 419 442 0.98
3 7 0.17 13 6.6 0.2 1 23 448 471 448 471 0.89
4 7 8.5e-05 0.0065 17.0 1.4 1 23 496 518 496 518 0.98
5 7 3.7e-07 2.8e-05 24.5 1.3 1 23 524 546 524 546 0.99
6 7 0.0079 0.61 10.8 0.4 2 23 552 573 551 573 0.96
7 7 0.0076 0.58 10.9 1.6 3 21 581 599 579 603 0.90

Sequence Information

Coding Sequence
ATGAGATGTGCGGTGCCGAATTGCCGGAACGCCTTTGTCTGCCGATCCAAAAGGAATCCGGATCAGCAGCCACAGGTGGGTTTCTTTCGGTTCCCCAAGTGCCCGGAAACATTCAAACTTTGGCTCGCATTCTGTGGTCTTACGGAGGACACCCTGAAACTGAAGAATCCCTGCGTTTGCATTGAGCACTTCAAGGACGAGGACATCGAGGGATCCTTGAAGTTCGAGATGGGTCTGGCCAAAAAGAGAACCTTGCGACCGGGAGCGGTTCCCTGCATAAACAGAAACCAAGAAAGTCCTTCGGAAAGAGCGCGTGAGGAAAGGACTCGGCGGCGCAGGAACCAAAAGCTGGTGGCCCAACTCCTGGCGGAAGATGAGGCCGAGTCGAGTGCTTCAGCGGCCTGTACGTTTGCCAGTCCACAGCCGGATAAAGTGGATCTATCAGAGGCTATAGCAATGGACTTTGATCCGCTAATGGGCAAGGATGAGCGAAAAGAACTGGAAAAGTGCCGCATCTGCTACAAGGACTTTGCTGTGGACTCCAGTGCCCGGGATCTCTTCGACGAGGCCAACAGCGTCCTGCTCTTCCATATAGAAGTCATTAGCGGCGTTTGGATCAGCCAGAAACCAGACGAACCCCAGCTCATGTGCCCTGCTTGCATTCTATCCCTCAACCAGGCCATTGATTTCCGGGAGATGTGCATTAGCACAGAGCTCAGGATCAGCCAAACCAAGTCCTTAGCCGAAACGGAACCAGTTAAATCGAAGATCTATGCTATAAGCGAAGATTCCGCTACTTCAGAGCCTGATTTGCACTCCGATTCAGAGTACACTCATATAGAAGCGATCGAGGATCCAGAGAAAGAGCCTGCGGAAGATGGCGCCACAAAGGAAGACCAATTAAGTCAAGTGCCAGCCGTAGAATCCACTGACCCCACCACTCAAGATCCACTCAGCGTGACCCTGGGGGCCAAGATTTTCAAGGAACTGATAGACCAATACACGGGACACGAAAAAAGTAGgccaaaaaaagaggcttCAATAGTTAAGAAGCCCAAGATCATAAAACCTGCTGTTCATGAACAGAAGCCAAAGCGCAGGGCCAATCCCAAGACGAAAGAGGAGAGAAACCTCATACGACGGGCCCAACTGCGGGCTAAAGCGCCGAACTTTGTGTGCGACCAGTGCGGACAGGCCTTTCGCATGGCGCACAACCTGAGGATACACATGCTGCGGCACAGCCGCACCAAGAACTACCAGTGCAGCGAGTGTCCGAAGACTTTCTACGACGCCTACATGCGCAACATGCACATCCGGATCAAGCACCGCGGGGAATCTCCCTTCGCATGCCGTTTCTGCAGCGAAACGTTTGCCTATGCGGGTGCGCGCCAAAAGCATGAAAGTGAGATCCACAATGCTGCTCCCCGTCTGATTGTAAAGCGAATCAATCCCAAGCCCATGCCCAAGCCACCAGAGGATGTGCGCTATCAGTGCAAACTGTGCCACAAGGATTACGCCTCCAAGTATGCACTAAGCTGGCATGTGAAGGCGCACACCGAAGCAAATCAATTCAAGTGCCAGCAGTGCAACAAGAGCTACTCGGATCCCAACGGGCTAAGGCGCCACTTGATGACCCACGAGAAGAGGCCGCTGCAATGCGATGTTTGCTTGAAAGGATTCTATCAGCGCACACGACTGCGGGAGCACGAGCTCATCCACACCGGAGAGCGTCCCTATTGGTGCGAGATCTGCAATGTTCACTTCCGCTACAAGTACAACATGAAGACTCATGCGAGCAGTAAAATGCATCAGGAAAACGCTCGTAAAATGGGCCAAGAACAATTAGTTGAAGACGAATGA
Protein Sequence
MRCAVPNCRNAFVCRSKRNPDQQPQVGFFRFPKCPETFKLWLAFCGLTEDTLKLKNPCVCIEHFKDEDIEGSLKFEMGLAKKRTLRPGAVPCINRNQESPSERAREERTRRRRNQKLVAQLLAEDEAESSASAACTFASPQPDKVDLSEAIAMDFDPLMGKDERKELEKCRICYKDFAVDSSARDLFDEANSVLLFHIEVISGVWISQKPDEPQLMCPACILSLNQAIDFREMCISTELRISQTKSLAETEPVKSKIYAISEDSATSEPDLHSDSEYTHIEAIEDPEKEPAEDGATKEDQLSQVPAVESTDPTTQDPLSVTLGAKIFKELIDQYTGHEKSRPKKEASIVKKPKIIKPAVHEQKPKRRANPKTKEERNLIRRAQLRAKAPNFVCDQCGQAFRMAHNLRIHMLRHSRTKNYQCSECPKTFYDAYMRNMHIRIKHRGESPFACRFCSETFAYAGARQKHESEIHNAAPRLIVKRINPKPMPKPPEDVRYQCKLCHKDYASKYALSWHVKAHTEANQFKCQQCNKSYSDPNGLRRHLMTHEKRPLQCDVCLKGFYQRTRLREHELIHTGERPYWCEICNVHFRYKYNMKTHASSKMHQENARKMGQEQLVEDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00602872;
90% Identity
iTF_00548101;
80% Identity
iTF_00548101;