Basic Information

Insect: Drosophila mimetica
Gene Symbol: ham
Assembly: GCA_037075245.1
Location: JBAMCH010000007.1:12849850-12870504[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.015 1.1 10.0 0.0 2 22 341 361 340 363 0.88

2 9 0.03 2.3 9.0 2.1 3 23 372 393 370 393 0.93

3 9 1.6e-07 1.3e-05 25.6 1.7 1 23 399 422 399 422 0.96

4 9 1e-06 7.9e-05 23.0 1.6 1 23 428 450 428 450 0.97

5 9 6.7e-05 0.0052 17.3 2.5 1 23 456 478 456 478 0.97

6 9 0.0017 0.13 12.9 1.4 2 21 486 505 485 506 0.94

7 9 6.4e-08 4.9e-06 26.8 3.2 1 23 948 970 948 970 0.98

8 9 4.4e-07 3.4e-05 24.2 0.5 1 23 976 999 976 999 0.97

9 9 7e-06 0.00054 20.4 1.3 1 23 1005 1027 1005 1027 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.015	1.1	10.0	0.0	2	22	341	361	340	363	0.88
2	9	0.03	2.3	9.0	2.1	3	23	372	393	370	393	0.93
3	9	1.6e-07	1.3e-05	25.6	1.7	1	23	399	422	399	422	0.96
4	9	1e-06	7.9e-05	23.0	1.6	1	23	428	450	428	450	0.97
5	9	6.7e-05	0.0052	17.3	2.5	1	23	456	478	456	478	0.97
6	9	0.0017	0.13	12.9	1.4	2	21	486	505	485	506	0.94
7	9	6.4e-08	4.9e-06	26.8	3.2	1	23	948	970	948	970	0.98
8	9	4.4e-07	3.4e-05	24.2	0.5	1	23	976	999	976	999	0.97
9	9	7e-06	0.00054	20.4	1.3	1	23	1005	1027	1005	1027	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGATATGTCATATCAGGCTCCAGCGGCGACGACTTCGATCCGAGTGCGAGTGCAGTGCGTCACCATCATCATCTCCATCACCTGGATCTGAGTGCCAGGAGTCAGGGCTTCAACTCGCTGCCTGAGCCCCTTGAGGATTCATTTGCCGCCCGCCATCGTTTGCCGCAGCAGGAACCGGTGGAAGGATCGCCCACGCGGCGTGATCATCGGGATCTTCAGGATCAGGAGCTCCTGCATCATCATCCCAATcacctccagcagcagcagcagcagcagcttcagcgACAACAGCCACCGCCTCCGACGTTGCCAATGTCCTTGGATCCTTCTGCCGCCGCCGACGGCATGGAGGCCTATTTAAAGGAGCGCGTCCAGGCGGAGCACATCCTGCAGGAGTGGGCGCGAAGGCGCGAACCCGTCTGTGATCTGGACATCCGCGACAGCGGCGGTGTCTACGCGAAGACGCCGCTCCAGAGGGGCACCCGCTACGGACCCTTCCCCATGAAGCTTAGCCACCAGCCCAACGATCCGCAGCTGGCGTGGAAGGCCAATGGTAGACACTATAATGGATGGCTGGAGCCCACAGATGATGTGTCCACGTGgttgaaaaaaattcgaaacgTTCAGGACGATGGCATTGGCGAGGCTAATTTACAGAGTTACATTAATGGCGGTTATctgTGGTACGAGACGAATCGGTATGTGAATGCTGGCAGTGAAATGGTCGTCGACGGGCGACCCAAAAGTCCCGTTCAACTGAACGAGAACTTCATGAACGGCGGCAAAGTcctggcggcagcagcagcagcagccgccgcagtGGCAGCCGCCAACTCCTCGGGTGGAAAGAGCGGGGGAGGGGGCAGCTCCCTGCCCAGCGATGATCGCAGCGATCGTGATAATGGTTCTTTGTACAGTGGTGACGAATTCTCCAAAGACAAGAAAAACTCCTCGCTAATCAGCCACGGAGATATCGATTTCACAGACGACGAAAACGGTTTCGATATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACTCTTGGACGAACATCTGGTAGGCGCTCATCATTTCAAGCAGGACGAATTCGGCTGCAAGCAGTGCCCCTTACGATTCTGCCATCGTCCTCTGCTGATCAAGCACGAAGCAATCTCCCACAATAATATACGGAAATATTCCTGCGAGAATTGCAGCAAGGTATTTTGTGACCCCTCGAATTTACAGCGGCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCATCCGTGTCCGGAGTGCGGGAAAACGTTCGGTACCTCATCGGGCCTGAAGCAGCACCAGCACATCCACAGTTCCGTCAAGCCCTTCGCCTGCGAAGTGTGCGCCaaggcgtatacgcaattctCGAACCTGTGCCGGCACAAGCGAATGCACGCCACCTGCCGGATGCAGATCAAGTGCGACAAGTGCAACCAGAGCTTCAGCACCATCACCTCACTGAGCAAGCACAAAAAGTTCTGTGATTCGACGGGTCCCGTGTATCGCAACCAGCACGTGAATCGCcaccatccgcatccgcattcgCATCAGCAGCATCAGTCGCATCAGCATCAGACGCACTTGGCCGCCACTGCCACCGCCACCTGTCCGGCGCCACCAAGGGAATCCCCGGAATCCTCATCCtcagccgctgccgccgccgttgcCGCCATGTCGACGCCGCCGAATCCCTTCCTGATGTTCCGCACCGCGCCACCATTCTTTCCCGGATTTCATCCGTACGGATTGTCCGCCTTTATGCCACAAAATGCTCTGCATCCCTCGAACATTCCCAtgtttttctcgaaaaatcCCATGGACATGGGCTGTGCCGCGCCAGAAATCACTTCCCCCATCTCCGCCTTTGATCAGAAGCTACCATTTAGTTTTCTGAACGGTGAGGCCAATAATTCGCAGGCCTATGACAAAGTGAAGGAAAAGGAGTTGGCTTTCAAGGCGGAGGAGAAACTAAAGAAGGAACCACTGCTGCAGGTTTCTGAGGGCGAAGATGACGAGAGTCGTAATTCAATGGACCTGAAGATGAAATTGGAAGTTGAGAAAAGTGAAACGAAATCGGAGGATCAGGATGAGATGAAGCGGGAACCCGAGCGGGTAAACAGTCCCGATCAACAGCAGGCTGAAGATGATAGGAAATCCATTGACATTGTGAGCACTCCACCGCCCGCAGACACGCCCTCTGGCGGAGATGCCCCGCTGGACCTGTCGATCTGTCGCAAGCGATCATCCTCAACATGCTTCTATGCGCCGCTGGAAGAAAATCTCCTGCTGAATCGGTTCATGCCGGGAATACATGAGTTTGAGGCCGAAAGGGAGCCGCCACTAAAAATGCGAAAGTCACACAGTTCGGCGGAGTCGTCCATCTCGCAAAAGTCCTTCAGGGGCAGCAGTCCCACGCCCACCGCCTCGCCGGGCCCCACCCCCTCGCCGTCGCCGCCCACGAGTGCGGGCGGTGAGCTGAGCAGCACCTCCGAGGGTGGAGCAGTGCcggcaacgacgacgacgacgtcggctgcagcagcagcggctgcggcggcggcatctGCAGCGGCGGGAGCCGTGGACCTGGCCGCCCTGGCTCACCTGACCCATCCGCAGAACCAGCCCGCCATACATCCGCTCTTTCTGGAGGAGATCTACCGCTCCGGGTTTCCTTTTTTATGCCCAACGGGCGGACGGCGCAGCATTGAGGCGCTGCTGGCGGGAGCCgccaatgcagcagcagccccaaAGCGGCCGCTTCCGCCCGTGAAATTCTCAACGGGACTCAAGACGAAGGATCGTTACTGCTGCAAGTTCTGCGGCAAGGTGTTCCCCCGATCCGCGAACCTGACGCGCCACCTGAGGACGCACACGGGCGAGCAGCCGTATCCCTGCAAGTACTGCGATCGCGCCTTCAGCATCTCCTCGAATCTGCAGCGTCACGTACGGAATATCCACAATAAGGAGCGACCCTTTCGCTGCGAACTCTGTGACCGGTCCTTTGGGCAGCAGACGAATCTCGATCGACATGTGAAGAAGCACGAATCGGAGGGCAACAACTTCCGGGATTCGCCCAGTTCCAATGGCATCGCCGAGCGGGAGGAGTACTTTGATGATATACGCAAGTTCATGAACCGGGTTTACACCCCCAATAGCCTGGCGGGCAATGAGGGTGACACCGAGGAGTATCCCAACAGCGATGATCAATCGGTGAACCTGGAAAAggatagcaacagcaacttcaacaacaacagcagtaacatcagcaacaacaacagcaacagcgctggcaacaacaacaacagctccaAGGCCATAACAATAAGCTCTTAA
Protein Sequence: MLFDRYVISGSSGDDFDPSASAVRHHHHLHHLDLSARSQGFNSLPEPLEDSFAARHRLPQQEPVEGSPTRRDHRDLQDQELLHHHPNHLQQQQQQQLQRQQPPPPTLPMSLDPSAAADGMEAYLKERVQAEHILQEWARRREPVCDLDIRDSGGVYAKTPLQRGTRYGPFPMKLSHQPNDPQLAWKANGRHYNGWLEPTDDVSTWLKKIRNVQDDGIGEANLQSYINGGYLWYETNRYVNAGSEMVVDGRPKSPVQLNENFMNGGKVLAAAAAAAAAVAAANSSGGKSGGGGSSLPSDDRSDRDNGSLYSGDEFSKDKKNSSLISHGDIDFTDDENGFDIRCEVCDKVYPDLELLDEHLVGAHHFKQDEFGCKQCPLRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCAKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTITSLSKHKKFCDSTGPVYRNQHVNRHHPHPHSHQQHQSHQHQTHLAATATATCPAPPRESPESSSSAAAAAVAAMSTPPNPFLMFRTAPPFFPGFHPYGLSAFMPQNALHPSNIPMFFSKNPMDMGCAAPEITSPISAFDQKLPFSFLNGEANNSQAYDKVKEKELAFKAEEKLKKEPLLQVSEGEDDESRNSMDLKMKLEVEKSETKSEDQDEMKREPERVNSPDQQQAEDDRKSIDIVSTPPPADTPSGGDAPLDLSICRKRSSSTCFYAPLEENLLLNRFMPGIHEFEAEREPPLKMRKSHSSAESSISQKSFRGSSPTPTASPGPTPSPSPPTSAGGELSSTSEGGAVPATTTTTSAAAAAAAAAASAAAGAVDLAALAHLTHPQNQPAIHPLFLEEIYRSGFPFLCPTGGRRSIEALLAGAANAAAAPKRPLPPVKFSTGLKTKDRYCCKFCGKVFPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLDRHVKKHESEGNNFRDSPSSNGIAEREEYFDDIRKFMNRVYTPNSLAGNEGDTEEYPNSDDQSVNLEKDSNSNFNNNSSNISNNNSNSAGNNNNSSKAITISS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00578702;
90% Identity: iTF_00578702;
80% Identity: -