Dmim001224.1
Basic Information
- Insect
- Drosophila mimetica
- Gene Symbol
- -
- Assembly
- GCA_037075245.1
- Location
- JBAMCH010000004.1:11713846-11715063[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0021 0.16 12.6 4.7 1 23 103 127 103 127 0.97 2 11 3.9e-05 0.003 18.1 0.9 1 23 132 154 132 154 0.98 3 11 5.2e-06 0.0004 20.8 0.3 1 23 158 180 158 180 0.97 4 11 2.3e-06 0.00018 21.9 1.8 2 23 183 205 183 205 0.96 5 11 3.5e-06 0.00027 21.4 0.2 1 23 211 233 211 233 0.97 6 11 2.9e-05 0.0022 18.5 4.7 1 23 240 262 240 262 0.99 7 11 1.4e-06 0.00011 22.6 0.8 1 23 266 288 266 288 0.97 8 11 0.0013 0.1 13.3 0.4 2 23 293 315 292 315 0.93 9 11 8.7e-05 0.0067 17.0 6.2 1 23 321 343 321 343 0.98 10 11 4.6e-06 0.00036 21.0 2.2 1 23 349 371 349 371 0.99 11 11 9.8e-06 0.00075 20.0 3.1 1 23 377 399 377 399 0.99
Sequence Information
- Coding Sequence
- ATGGAGTCTTCAACAAGTCTGCAGGATGAATTTATCAAGGAAGAAGTGTCGGAAAACGAGATGGAAGAAGAAGCTCCTGAAGATTTGGTAGGCCAGAATTCCCCAAGAGAAGAATTCCAAGACGAAGACGAATGCATAGTGAAGAACGAGCCACTGGAagatgacgatgacgaggaTGAATACTCCTCCATTTCAAACGGCGACATCGATATAACCTACGACGAAGTGAAAATCGAGGAAGCAGAAGATGATATCCTTGATTCACcctctgaatctgaatcttcTAACAATGCAACTAAGCTCCCGCATAAATGCTCTCAGTGTGGACTGAACTTGCAGTGTAAAACCGAGTCGGGTCTCAGGCGACACATGCGAACCCATACGGACCACAAGTTCATGTGTGCCCACTGCCCAAGGACATTTATACGGGCTGCCAATCGGAACAGACATGCTCTCACCCACCAAGGATCGTTTCAGTGTGCCAAATGTCCCAAGACATTTAACCAGGACGCAGATCTTCAGGCACACCAACAAGATCACTTAAGGCAGTGTTCCCAGTGCCCGAAGACATTCAAGAATAAAACCTATCTCAGGCAGCACATACAGCAAGTGCACGCAGAAGGACGATTATTTGAGTGTACCCTCTGCCCGAAGTCCTTCAGCTATCCGGCTGGACTTCGGAAACATTCGCTAGTCCACACAAAAGAGCCCACCATCTACAAGTGTTCCCACTGCCCAAAGACCTATACAATGGGttacaactttaaaaaacatcTTCTCACCCACGAACGAACGTTTCAGTGCTCTAAATGTCCACGATCTTTCAGCACGGACTCGGAACTTCAGGCACACCGGGAAAATCATGCTAAGGAGATACCGTGCACGCGGTGTTCCAGGACATTTACCTCTAATCTAGGTCTCAAACTGCACTTATTGCAGGTGCACTCGGAAGAAGGCACATTTAAGTGTACCCACTGCCCAAGGACCTTTATCCATGTATCCAGACTTCAGAGACATTCCCGGAGCCACACAGGAGAGCGGCCCTTCAAGTGCACCCAATGCGAGAAGGGCTTTACAACGAGACTGTATCTACGCGTACATCTAAGATCGCATACCGGAGAACGACCCTACAAGTGTCCGCAGTGCTCAAAGGACTTCTGCGACCGCGGCAGTATGAAGCGACACCTGGACACCCACAAAAGGATTAGTGTAGCATAG
- Protein Sequence
- MESSTSLQDEFIKEEVSENEMEEEAPEDLVGQNSPREEFQDEDECIVKNEPLEDDDDEDEYSSISNGDIDITYDEVKIEEAEDDILDSPSESESSNNATKLPHKCSQCGLNLQCKTESGLRRHMRTHTDHKFMCAHCPRTFIRAANRNRHALTHQGSFQCAKCPKTFNQDADLQAHQQDHLRQCSQCPKTFKNKTYLRQHIQQVHAEGRLFECTLCPKSFSYPAGLRKHSLVHTKEPTIYKCSHCPKTYTMGYNFKKHLLTHERTFQCSKCPRSFSTDSELQAHRENHAKEIPCTRCSRTFTSNLGLKLHLLQVHSEEGTFKCTHCPRTFIHVSRLQRHSRSHTGERPFKCTQCEKGFTTRLYLRVHLRSHTGERPYKCPQCSKDFCDRGSMKRHLDTHKRISVA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -