Dmim002021.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mimetica
Gene Symbol
-
Assembly
GCA_037075245.1
Location
JBAMCH010000004.1:18870977-18872756[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00011 0.0085 16.7 0.1 3 23 232 252 230 252 0.97
2 12 1.2e-05 0.00094 19.7 2.4 3 23 264 284 262 284 0.96
3 12 3.9e-06 0.0003 21.2 0.1 1 23 290 312 290 312 0.99
4 12 7.3e-08 5.6e-06 26.7 1.1 2 23 319 340 319 340 0.98
5 12 6.3e-06 0.00049 20.6 0.7 1 23 346 368 346 368 0.98
6 12 3e-07 2.3e-05 24.7 1.1 1 23 374 396 374 396 0.99
7 12 1.8e-07 1.4e-05 25.4 4.7 1 23 402 424 402 424 0.99
8 12 8.9e-07 6.8e-05 23.2 5.9 1 23 430 452 430 452 0.99
9 12 1.5e-05 0.0011 19.4 0.8 1 23 458 480 458 480 0.98
10 12 3.4e-05 0.0026 18.3 0.8 1 23 488 510 488 510 0.97
11 12 0.00025 0.019 15.5 2.5 1 23 520 542 520 542 0.97
12 12 4.7e-05 0.0036 17.8 3.4 1 23 547 569 547 569 0.97

Sequence Information

Coding Sequence
ATGGAAAGACCGTCGGACGCCATCATGGGAAAGAACTGCAGGGCTTGCGCCGAACACTCGGCCATACTGGTGGACCTCTTCTCCACGGACATCTCCGATCCACCAATTTGGGAGATGCTGAACTCCTTTCTCCCCGAGAACTGCCGCGTCGACAAGGATGCAATGCCCCAGAAGATCTGTCCCACCTGCCTGGTGGCCGCCCAAAATGCCTTCTACTTCAGGAACAAGTGCGTGCAGAGTTTCCAGTATTTTACACATCTCCTCCTCCTGGACAAATCCGCCCCGAGTCAGGGTAGAACTCGGAGCAGAAAAGGTGACAAGAATCCTCTAAAGAACTTCGAGATGGTCGGCTGCGAGGACCCATTGGACACCAATGGTTCTGGAAAGGATGGGGATCAGCTTGTTTTGAAAACAGACATTGACTCCGAGCCAACAGATGGTTTGCTAACCAAAGAACAGGAGCCTCAACCGTTGCACGAAGTATTCGAAAtaACTATGGGCGATATAAAAACAGAAGAGGTAATGTGCAACGATGAGACATTCGAAGATGCCTTTGCAGAAGACGATAATAACGATGATTTTGAGGCCGAGTCTGATGAATGGTCAGCAGGGTCGTCGGAGGACGACGAAGAGACCTGGATGGCGGGCAGTGGAGAGCCGAAAGCGGGTGACGAGACGAACCAGTCGCTGCTGTGCACCGAGTGTGGCGTGACCTACCCGACGGCCAAGTCGCTGGCGAAGCACATAGCTAGGCACCGGGCGCAGGACGATCCGCAAAAGCCGCATCTGTGTGACTTTTGCGGCAGAGGATTCCGGACCAACGCTCAGCTGACAATCCACAGGCGCAAGCACACCGGAGAGCGTCCGTTTCAATGTCCTCTCTGCCCGAAAGCGTATACCCAGGGTCCTACTTTGAAGGCTCACATGCTCACCCACGAGGAGCAGAAGGGTGAGAAGTGCCCGGAGTGCGAGAAGACTTTTTACACCCGGGCCAACCTGAGGGCCCACATGAAGCGTCACTCCGGCGAAAGACCATACGAGTGTCCAGAATGTTCACAGACCTTCTCGAAGAATTCGGGCCTTAAGTTACACAGTCGACTGCATAGGCCGGATCGGCCCTTTAAGTGCGAGCTGTGCGGCAAGGGATTTGTCCAGAACCAGCATTTGATCACCCACCTGCGGGTCCACAACGGGGATCGCCAGTTCAAGTGCCCCGACTGCGACAAGTGCTTCTACGAGAAATCCAACATGCTGAAGCATCAGCGCACGCACTCGGGCATAAAGCCCTTTAAATGCGAAGAGTGCGGCCAGGCGTTTTCGCACAACCATCACCTGAAGAGTCACCTACGCATCCACACCGGAGAAAAGCCCTACAAGTGCGACCAGTGCGGCAAGGGCTTTTGTGCGAATCAGTCTCTTGCCAAGCATATCCTTTGGCATGTGGAAAACAATGATCGACCCTTCAAGTGCACCAAATGTCCCAAAGCCTTTGACTCGCAGCAGAGTTTAAAAGGGCACGAGAAGGCGCACAGAAAGCCGGAATTACCAAAGACGCTACATCAATGCCCACACTGCGACGTCAGCTTTGCCATCAAAAAGACCTTGGACAAGCATATCACTAGCCATAAGATTCGGCCCCACCCATGTCCGCATTGTACAGAAGGATTCTTCTCCCAGAAGAGCTTGGAAAGACATCTCAAATCGCACAAAACGAAAGAATAA
Protein Sequence
MERPSDAIMGKNCRACAEHSAILVDLFSTDISDPPIWEMLNSFLPENCRVDKDAMPQKICPTCLVAAQNAFYFRNKCVQSFQYFTHLLLLDKSAPSQGRTRSRKGDKNPLKNFEMVGCEDPLDTNGSGKDGDQLVLKTDIDSEPTDGLLTKEQEPQPLHEVFEITMGDIKTEEVMCNDETFEDAFAEDDNNDDFEAESDEWSAGSSEDDEETWMAGSGEPKAGDETNQSLLCTECGVTYPTAKSLAKHIARHRAQDDPQKPHLCDFCGRGFRTNAQLTIHRRKHTGERPFQCPLCPKAYTQGPTLKAHMLTHEEQKGEKCPECEKTFYTRANLRAHMKRHSGERPYECPECSQTFSKNSGLKLHSRLHRPDRPFKCELCGKGFVQNQHLITHLRVHNGDRQFKCPDCDKCFYEKSNMLKHQRTHSGIKPFKCEECGQAFSHNHHLKSHLRIHTGEKPYKCDQCGKGFCANQSLAKHILWHVENNDRPFKCTKCPKAFDSQQSLKGHEKAHRKPELPKTLHQCPHCDVSFAIKKTLDKHITSHKIRPHPCPHCTEGFFSQKSLERHLKSHKTKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00536909;
90% Identity
-
80% Identity
-