Dmim006613.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mimetica
Gene Symbol
-
Assembly
GCA_037075245.1
Location
JBAMCH010000007.1:5901092-5903982[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.084 6.5 7.6 4.0 3 23 190 211 189 211 0.90
2 17 0.013 0.99 10.1 0.9 1 23 215 237 215 237 0.98
3 17 8.1e-05 0.0063 17.1 0.5 1 23 242 264 242 264 0.98
4 17 0.0016 0.12 13.0 8.6 1 23 268 290 268 290 0.98
5 17 7.3e-06 0.00056 20.4 5.6 1 23 296 318 296 318 0.98
6 17 9.5e-06 0.00073 20.0 8.3 1 21 324 344 324 346 0.96
7 17 1.3e-06 0.0001 22.7 1.2 1 23 352 374 352 374 0.98
8 17 1.5e-06 0.00012 22.5 3.6 1 23 379 401 379 401 0.98
9 17 0.077 6 7.7 3.3 3 23 586 607 585 607 0.90
10 17 0.0097 0.75 10.5 0.8 1 23 611 633 611 633 0.98
11 17 8.1e-05 0.0063 17.1 0.5 1 23 638 660 638 660 0.98
12 17 0.0016 0.12 13.0 8.6 1 23 664 686 664 686 0.98
13 17 4.3e-06 0.00033 21.1 2.2 3 23 694 714 692 714 0.98
14 17 1.7e-07 1.3e-05 25.5 5.6 1 21 720 740 720 742 0.96
15 17 9.5e-06 0.00073 20.0 8.3 1 21 748 768 748 770 0.96
16 17 1.3e-06 0.0001 22.7 1.2 1 23 776 798 776 798 0.98
17 17 1.5e-06 0.00012 22.5 3.6 1 23 803 825 803 825 0.98

Sequence Information

Coding Sequence
ATGGTGGCCTTGTGTCGCGTTTGCAATCGGAATCCGGGACGCCTGATAAACATATTTGATGGGACGCCGGATTTAGCCCTAATTGTTTCCCAATATATTGGATTGGAAGTTAAAAGAGGGGATTCATTTCCAGAGACGGTTTGCACTATGTGTCTGGAGGAAGCTCGGAATTCATATGGGAACGAAGAAGCCTGCGAGGATGAAGTCTTCGAAATCATAGAGTTCCATGATGAGGAAGATCACCACGAGGCGGACCCATTAGAGGAAGACGGCTGTCAAGAAGGGGATGAGGAGTTTCTGGAGGAGGATGTATCCATAACACCGGACTGCGAGTTGGGGGAATCAAGTGGTAACCAGGAATTTCAAGtgaaagaagaaaaattcAACAAGACACAGTCACTCcattcgaaaataaaaaacgaaccAATTGAAGATGACGGGTTGTTCGATGAGGAAGTCAGCCAGGTGGCGGATTGCCTGGTGAAGAACGAACCAATTGAAGACGATTTATCCGAGGATGAACTGTGCACAATGGCAGTGGAGCAAGCAAAGCTTCCCGAGAACaagtgccgctgctgccgaAAGTCCTTTCGTTCGGCTGCCCGCCTTAAACGACACGAGCGAGAAGTCCACAAGCGAACTTACCGATGTGTTTCTTGCAGTAAGAGATTTTTGACACAGGACTCTCTGGACTCGCACGTCCTGACTCACGAGGAAACCCCCTTCAGTTGTACTTTCTGCCCTAAGTATTTTCCGGATGATTCTACACTCAATGAGCACATTTCTACGCACTTGCGACCGCACAAGTGCTGTCACTGCCCGAAGTCCTTTCTTTCGTCATACGACCTTAAGAGACACACGCGGATCCACACGGGCGAACGACCCTACTGTTGTGAACACTGTCCGAAGACCTTTACGGATAGAACTTCCTTGACGTCGCACACAAGGATACACAAGGGGGAGAAGCCCTACAAGTGCACCGAATGCACGAAGTCCTTTTCACAGCAGTGCAACCTACAGAGGCACATGCGATGCCACACTGGAGAAAGACCCTACAAATGCCGCTTCTGCCCCAAGACCTTTACACAGCTTTCCAATCTGGGGCTGCACATGAGGGCTCATACGGGAGAGCGGTTCCATTGCACTATGTGCCCCAAGTCCTTTGCCTATAATAACGATCTTAAAAAACACCTGCGCACCCACTCCGAGGATAGAATCCAgGCTATGGTGGCCTTGTGTCGCGTTTGCAATCGGAATCCGGGACGCCTGATAAACATATTCGATGGGACGCCGGATTTAGCCCTAATTGTTTCCCAATATATTGGATTGGCAGTTCAACGCGGGGATTCATTTCCAGAGACTGTTTGCACTATGTGCCTGGAGGAAGCTCGGAATTCATATGGGAACGAAGAAGCCTGCGAGGATGAAGTCTTCGAAATCATAGAATTCCATGATGAGGAAGATCACCACGAGGCGGACCCATTAGAGGGAGACGGCTATCAAGAAGGCGATGAGGAGGATTTGATGGAGGAGGATGTATCCATAACACCGGACTGCGAGTTGGGGGAATCAAGTGGTAACCAGTCACTCcatgcgaaaataaaaaacgaaccAATTGAAGATGACGGGTTGTTCGATGAGGAAGTCAGCCAGGTGGCGGATTGCCTGGTGAAGAACGAACCAATTGAAGACGATTTATCCGAGGATGAACTGTGCACAATGGCAGTGGAGCAAGCAAAGCTTCCCGAGAACAAGTGCCGCTGCTGTCGAAAGGTTTTTCGTTCGGCTGCCCGCCTTAAACGACACGAGCGAGAAGTCCACAAGCGAACTTACCGATGTGCTTCTTGCAGTAAGAGATTTTTGACACAGGACTCTCTGGACTCGCACGTCCTGACTCACGAGGAAACCCCATTCAGTTGTACTTTCTGCCCTAAGTATTTTCCGGATGATTCTACACTCAATGAGCACATTTCTACGCACTTGCGACCGCACAAGTGCTGTCACTGCCCGAAGTCCTTTCTTTCGTCATATGACCTTAAGAGACACACGCGGATCCACACGGGCGAACGACCCTACGGTTGTGAACACTGTCCGAAGACCTTTACGGATAGAACTTCGTTGACGTCGCACACAAGGATACACAAGGGGGAGAAACCCTACAAGTGCACCGAATGCACGAAGTCCTTTTCACAGCAGAGCAACCTACAGAGGCACATGCGATGCCACAAGGGGGAGAAACCCTACAAGTGCACCGAATGCACGAAGTCCTTTTCACAGCAGTGCAACCTACAGAGGCACATGCGATGCCACACTGGAGAAAGACCCTACAAATGCCGCTTCTGCCCCAAGACCTTTACACAGCTTTCCAATCTGGGGCTGCACATGAGGGCTCATACGGGAGAACGGTTCCATTGCACCATGTGCCCCAAGTCCTTCGCCTATAATAACGATCTTAAAAAACACCTGCGCACCCACTCCGAGGATAGAATCCAGTGA
Protein Sequence
MVALCRVCNRNPGRLINIFDGTPDLALIVSQYIGLEVKRGDSFPETVCTMCLEEARNSYGNEEACEDEVFEIIEFHDEEDHHEADPLEEDGCQEGDEEFLEEDVSITPDCELGESSGNQEFQVKEEKFNKTQSLHSKIKNEPIEDDGLFDEEVSQVADCLVKNEPIEDDLSEDELCTMAVEQAKLPENKCRCCRKSFRSAARLKRHEREVHKRTYRCVSCSKRFLTQDSLDSHVLTHEETPFSCTFCPKYFPDDSTLNEHISTHLRPHKCCHCPKSFLSSYDLKRHTRIHTGERPYCCEHCPKTFTDRTSLTSHTRIHKGEKPYKCTECTKSFSQQCNLQRHMRCHTGERPYKCRFCPKTFTQLSNLGLHMRAHTGERFHCTMCPKSFAYNNDLKKHLRTHSEDRIQAMVALCRVCNRNPGRLINIFDGTPDLALIVSQYIGLAVQRGDSFPETVCTMCLEEARNSYGNEEACEDEVFEIIEFHDEEDHHEADPLEGDGYQEGDEEDLMEEDVSITPDCELGESSGNQSLHAKIKNEPIEDDGLFDEEVSQVADCLVKNEPIEDDLSEDELCTMAVEQAKLPENKCRCCRKVFRSAARLKRHEREVHKRTYRCASCSKRFLTQDSLDSHVLTHEETPFSCTFCPKYFPDDSTLNEHISTHLRPHKCCHCPKSFLSSYDLKRHTRIHTGERPYGCEHCPKTFTDRTSLTSHTRIHKGEKPYKCTECTKSFSQQSNLQRHMRCHKGEKPYKCTECTKSFSQQCNLQRHMRCHTGERPYKCRFCPKTFTQLSNLGLHMRAHTGERFHCTMCPKSFAYNNDLKKHLRTHSEDRIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-